Charles A Roessner

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. ncbi request reprint Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii)
    Charles A Roessner
    Center for Biological NMR, Department of Chemistry, Texas A and M University, College Station, TX 77843 3255, USA
    Microbiology 148:1845-53. 2002
  2. ncbi request reprint Mutagenesis identifies a conserved tyrosine residue important for the activity of uroporphyrinogen III synthase from Anacystis nidulans
    Charles A Roessner
    Center for Biological NMR, Department of Chemsitry, P O Box 30012, Texas A and M University, College Station, TX 77842 3012, USA
    FEBS Lett 525:25-8. 2002
  3. ncbi request reprint Genetically engineered production of 1-desmethylcobyrinic acid, 1-desmethylcobyrinic acid a,c-diamide, and cobyrinic acid a,c-diamide in Escherichia coli implies a role for CbiD in C-1 methylation in the anaerobic pathway to cobalamin
    Charles A Roessner
    Center for Biological NMR, Department of Chemistry, Texas A and M University, College Station, Texas 77843 3255, USA
    J Biol Chem 280:16748-53. 2005
  4. pmc Fine-tuning our knowledge of the anaerobic route to cobalamin (vitamin B12)
    Charles A Roessner
    Department of Chemistry, Center for Biological NMR, Texas A and M University, College Station, 77843 3255, USA
    J Bacteriol 188:7331-4. 2006
  5. ncbi request reprint Genetically engineered synthesis and structural characterization of cobalt-precorrin 5A and -5B, two new intermediates on the anaerobic pathway to vitamin B12: definition of the roles of the CbiF and CbiG enzymes
    Yasuhiro Kajiwara
    Center for Biological NMR, Department of Chemistry, Texas A and M University, P O Box 30012, College Station, Texas 77842 3012, USA
    J Am Chem Soc 128:9971-8. 2006
  6. ncbi request reprint Use of cobA and cysGA as red fluorescent indicators
    Charles A Roessner
    Department of Chemistry, Texas A and M University, College Station, TX, USA
    Methods Mol Biol 183:19-30. 2002
  7. pmc Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium
    Evelyne Raux
    School of Biological Sciences, Queen Mary, University of London, Mile End Road, London E1 4NS, UK
    Biochem J 370:505-16. 2003
  8. ncbi request reprint Structure/function studies on a S-adenosyl-L-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis
    Jitka Vévodová
    Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, UK
    J Mol Biol 344:419-33. 2004
  9. ncbi request reprint Identification and characterization of a novel vitamin B12 (cobalamin) biosynthetic enzyme (CobZ) from Rhodobacter capsulatus, containing flavin, heme, and Fe-S cofactors
    Helen M McGoldrick
    School of Biological Sciences, Queen Mary, University of London, Mile End Road, London E1 4NS, United Kingdom
    J Biol Chem 280:1086-94. 2005

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii)
    Charles A Roessner
    Center for Biological NMR, Department of Chemistry, Texas A and M University, College Station, TX 77843 3255, USA
    Microbiology 148:1845-53. 2002
    ..The functions of the P. freudenreichii B12 pathway genes are discussed, and a mechanism for the regulation of cobalamin and propionic acid production by oxygen in this organism is proposed...
  2. ncbi request reprint Mutagenesis identifies a conserved tyrosine residue important for the activity of uroporphyrinogen III synthase from Anacystis nidulans
    Charles A Roessner
    Center for Biological NMR, Department of Chemsitry, P O Box 30012, Texas A and M University, College Station, TX 77842 3012, USA
    FEBS Lett 525:25-8. 2002
    ..Of the nine conserved amino acids altered, only a single tyrosine mutant (Y166F) showed any significant decrease in activity suggesting this residue is critical for proper substrate binding and/or catalysis...
  3. ncbi request reprint Genetically engineered production of 1-desmethylcobyrinic acid, 1-desmethylcobyrinic acid a,c-diamide, and cobyrinic acid a,c-diamide in Escherichia coli implies a role for CbiD in C-1 methylation in the anaerobic pathway to cobalamin
    Charles A Roessner
    Center for Biological NMR, Department of Chemistry, Texas A and M University, College Station, Texas 77843 3255, USA
    J Biol Chem 280:16748-53. 2005
    ....
  4. pmc Fine-tuning our knowledge of the anaerobic route to cobalamin (vitamin B12)
    Charles A Roessner
    Department of Chemistry, Center for Biological NMR, Texas A and M University, College Station, 77843 3255, USA
    J Bacteriol 188:7331-4. 2006
  5. ncbi request reprint Genetically engineered synthesis and structural characterization of cobalt-precorrin 5A and -5B, two new intermediates on the anaerobic pathway to vitamin B12: definition of the roles of the CbiF and CbiG enzymes
    Yasuhiro Kajiwara
    Center for Biological NMR, Department of Chemistry, Texas A and M University, P O Box 30012, College Station, Texas 77842 3012, USA
    J Am Chem Soc 128:9971-8. 2006
    ....
  6. ncbi request reprint Use of cobA and cysGA as red fluorescent indicators
    Charles A Roessner
    Department of Chemistry, Texas A and M University, College Station, TX, USA
    Methods Mol Biol 183:19-30. 2002
  7. pmc Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium
    Evelyne Raux
    School of Biological Sciences, Queen Mary, University of London, Mile End Road, London E1 4NS, UK
    Biochem J 370:505-16. 2003
    ..Sequence alignments suggest that SirB and CbiX share a similar active site to the cobaltochelatase, CbiK, from Salmonella enterica...
  8. ncbi request reprint Structure/function studies on a S-adenosyl-L-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis
    Jitka Vévodová
    Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, UK
    J Mol Biol 344:419-33. 2004
    ..The activity of these variants is interpreted with respect to the structure of the enzyme...
  9. ncbi request reprint Identification and characterization of a novel vitamin B12 (cobalamin) biosynthetic enzyme (CobZ) from Rhodobacter capsulatus, containing flavin, heme, and Fe-S cofactors
    Helen M McGoldrick
    School of Biological Sciences, Queen Mary, University of London, Mile End Road, London E1 4NS, United Kingdom
    J Biol Chem 280:1086-94. 2005
    ..A mechanism for Orf663 (CobZ) in cobalamin biosynthesis is proposed...