J Marc Rhoads

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Lactobacillus reuteri DSM 17938 changes the frequency of Foxp3+ regulatory T cells in the intestine and mesenteric lymph node in experimental necrotizing enterocolitis
    Yuying Liu
    Divisions of Gastroenterology and Allergy Immunology, Department of Pediatrics, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, USA
    PLoS ONE 8:e56547. 2013
  2. pmc Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine
    Yuying Liu
    Department of Pediatrics, Division of Gastroenterology, University of Texas Health Science Center at Houston Medical School, USA
    Am J Physiol Gastrointest Liver Physiol 302:G608-17. 2012
  3. doi request reprint Glutamine, arginine, and leucine signaling in the intestine
    J Marc Rhoads
    Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Amino Acids 37:111-22. 2009
  4. ncbi request reprint Arginine stimulates cdx2-transformed intestinal epithelial cell migration via a mechanism requiring both nitric oxide and phosphorylation of p70 S6 kinase
    J Marc Rhoads
    Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA
    J Nutr 138:1652-7. 2008
  5. doi request reprint Altered fecal microflora and increased fecal calprotectin in infants with colic
    J Marc Rhoads
    Department of Pediatrics, University of Texas Health Sciences Center at Houston School of Medicine, Houston, TX 77030, USA
    J Pediatr 155:823-828.e1. 2009
  6. pmc Role of mTOR signaling in intestinal cell migration
    J Marc Rhoads
    Div of Gastroenterology, Dept of Pediatrics, Univ of Texas Medical School at Houston, 6431 Fannin St, MSB 7 137, Houston, TX 77030, USA
    Am J Physiol Gastrointest Liver Physiol 291:G510-7. 2006
  7. ncbi request reprint Intestinal ribosomal p70(S6K) signaling is increased in piglet rotavirus enteritis
    J Marc Rhoads
    Department of Pediatrics, Ochsner Clinic Foundation and Ochsner Children s Research Institute, New Orleans, Louisiana, USA
    Am J Physiol Gastrointest Liver Physiol 292:G913-22. 2007
  8. pmc Safety and tolerability of Lactobacillus reuteri DSM 17938 and effects on biomarkers in healthy adults: results from a randomized masked trial
    Nisha Mangalat
    Department of Pediatrics, University of Texas Medical School at Houston, Houston, Texas, United States of America
    PLoS ONE 7:e43910. 2012
  9. pmc FoxP3⁺ regulatory T cells attenuate experimental necrotizing enterocolitis
    Bridgette M Dingle
    Department of Pediatrics, The University of Texas Medical School, Houston, Texas, United States of America
    PLoS ONE 8:e82963. 2013
  10. doi request reprint Arginine and citrulline protect intestinal cell monolayer tight junctions from hypoxia-induced injury in piglets
    John C Chapman
    Department of Pediatrics, Division of Neonatology, University of Texas Health Science Center, Houston, Texas, USA
    Pediatr Res 72:576-82. 2012

Collaborators

Detail Information

Publications17

  1. pmc Lactobacillus reuteri DSM 17938 changes the frequency of Foxp3+ regulatory T cells in the intestine and mesenteric lymph node in experimental necrotizing enterocolitis
    Yuying Liu
    Divisions of Gastroenterology and Allergy Immunology, Department of Pediatrics, The University of Texas Health Science Center at Houston Medical School, Houston, Texas, USA
    PLoS ONE 8:e56547. 2013
    ..Probiotic-facilitated development of Tregs might play an important role in the prevention of NEC...
  2. pmc Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine
    Yuying Liu
    Department of Pediatrics, Division of Gastroenterology, University of Texas Health Science Center at Houston Medical School, USA
    Am J Physiol Gastrointest Liver Physiol 302:G608-17. 2012
    ..reuteri strains has potential therapeutic value in our NEC model and in enteritis associated with cow milk feeding. These results support the concept that L. reuteri may represent a valuable treatment to prevent NEC...
  3. doi request reprint Glutamine, arginine, and leucine signaling in the intestine
    J Marc Rhoads
    Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Amino Acids 37:111-22. 2009
    ..Therefore, through cellular signaling mechanisms, arginine, glutamine, and leucine play crucial roles in intestinal growth, integrity, and function...
  4. ncbi request reprint Arginine stimulates cdx2-transformed intestinal epithelial cell migration via a mechanism requiring both nitric oxide and phosphorylation of p70 S6 kinase
    J Marc Rhoads
    Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA
    J Nutr 138:1652-7. 2008
    ....
  5. doi request reprint Altered fecal microflora and increased fecal calprotectin in infants with colic
    J Marc Rhoads
    Department of Pediatrics, University of Texas Health Sciences Center at Houston School of Medicine, Houston, TX 77030, USA
    J Pediatr 155:823-828.e1. 2009
    ..We explored whether gut inflammation, colonic fermentation, and/or an altered colonic flora could provide a pathophysiological mechanism for colic...
  6. pmc Role of mTOR signaling in intestinal cell migration
    J Marc Rhoads
    Div of Gastroenterology, Dept of Pediatrics, Univ of Texas Medical School at Houston, 6431 Fannin St, MSB 7 137, Houston, TX 77030, USA
    Am J Physiol Gastrointest Liver Physiol 291:G510-7. 2006
    ..We conclude that mTOR/p70(s6k) signaling is essential to intestinal cell migration, is activated by ARG, involves both nuclear and cytoplasmic events, and may play a role in intestinal repair...
  7. ncbi request reprint Intestinal ribosomal p70(S6K) signaling is increased in piglet rotavirus enteritis
    J Marc Rhoads
    Department of Pediatrics, Ochsner Clinic Foundation and Ochsner Children s Research Institute, New Orleans, Louisiana, USA
    Am J Physiol Gastrointest Liver Physiol 292:G913-22. 2007
    ..In conclusion, intestinal activation of p70(S6K) was not inhibited by malnutrition but was strongly activated during an active state of mucosal regeneration...
  8. pmc Safety and tolerability of Lactobacillus reuteri DSM 17938 and effects on biomarkers in healthy adults: results from a randomized masked trial
    Nisha Mangalat
    Department of Pediatrics, University of Texas Medical School at Houston, Houston, Texas, United States of America
    PLoS ONE 7:e43910. 2012
    ..There are few carefully-designed studies investigating the safety of individual probiotics approved under Investigational New Drug policies...
  9. pmc FoxP3⁺ regulatory T cells attenuate experimental necrotizing enterocolitis
    Bridgette M Dingle
    Department of Pediatrics, The University of Texas Medical School, Houston, Texas, United States of America
    PLoS ONE 8:e82963. 2013
    ..Adoptive transfer of Tregs attenuates the severity of NEC by limiting the immune response. Strategies to enhance Tregs have a therapeutic potential in controlling the development of NEC. ..
  10. doi request reprint Arginine and citrulline protect intestinal cell monolayer tight junctions from hypoxia-induced injury in piglets
    John C Chapman
    Department of Pediatrics, Division of Neonatology, University of Texas Health Science Center, Houston, Texas, USA
    Pediatr Res 72:576-82. 2012
    ..We investigated whether Arg or its precursor, citrulline (Cit), protects intestinal tight junctions (TJs) from hypoxia (HX) and determined whether inducible nitric oxide (NO) plays a role...
  11. ncbi request reprint Corticosteroid-responsive enteropathy of infancy
    Steven N Lichtman
    Department of Pediatrics, University of North Carolina at Chapel Hill, 27599 7220, USA
    J Health Popul Nutr 23:331-8. 2005
    ..Corticosteroids were uneventfully weaned over a four-month period. The results suggest that a trial of corticosteroids in infants with unresponsive persistent diarrhoea of unknown origin is beneficial and deserves prospective evaluation...
  12. ncbi request reprint Arginine activates intestinal p70(S6k) and protein synthesis in piglet rotavirus enteritis
    Benjamin A Corl
    Department of Animal Sciences, North Carolina State University, Raleigh, NC 27695, USA
    J Nutr 138:24-9. 2008
    ....
  13. ncbi request reprint Research agenda for pediatric gastroenterology, hepatology and nutrition: secretion and diarrhea. Report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition for the Children's Digestive Health and Nutrition Foundation
    Wayne I Lencer
    Children s Digestive Health and Nutrition Foundation, PO Box 6, Flourtown, PA 19031, USA
    J Pediatr Gastroenterol Nutr 35:S246-9. 2002
  14. ncbi request reprint Inducible nitric oxide synthase mediates early epithelial repair of porcine ileum
    Jody L Gookin
    Department of Anatomy, Physiological Sciences, and Radiology, School of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, USA
    Am J Physiol Gastrointest Liver Physiol 283:G157-68. 2002
    ..These results demonstrate that iNOS-derived NO is a key mediator of early villous reepithelialization following acute mucosal injury...
  15. ncbi request reprint Oral bovine serum concentrate improves cryptosporidial enteritis in calves
    Elaine Hunt
    Department of Anatomy, Physiology, and Radiological Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, USA
    Pediatr Res 51:370-6. 2002
    ..05). BSC should be studied as a treatment for human cryptosporidiosis...
  16. ncbi request reprint Arginine deficiency in preterm infants: biochemical mechanisms and nutritional implications
    Guoyao Wu
    Faculty of Nutrition, Texas A and M University, College Station, TX 77843, USA
    J Nutr Biochem 15:442-51. 2004
    ..This new knowledge will be beneficial for designing the next generation of enteral and parenteral amino acid solutions to optimize nutrition and health in this compromised population...
  17. ncbi request reprint Persistent and chronic diarrhea and malabsorption: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition
    Zulfiqar A Bhutta
    J Pediatr Gastroenterol Nutr 39:S711-6. 2004