CHARLES PATRICK REYNOLDS

Summary

Affiliation: Texas Tech University Health Sciences Center
Country: USA

Publications

  1. doi request reprint Initial testing (stage 1) of the phosphatidylinositol 3' kinase inhibitor, SAR245408 (XL147) by the pediatric preclinical testing program
    C Patrick Reynolds
    Cancer Center, Cancer Center, Texas Tech University Health Sciences Center, Lubbock, Texas 79430 6450, USA
    Pediatr Blood Cancer 60:791-8. 2013
  2. pmc The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA
    Philipp Kapranov
    Helicos BioSciences Corporation, One Kendall Square, Building 700, Cambridge, MA 02139, USA
    BMC Biol 8:149. 2010
  3. pmc Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins
    Michael D Hadjidaniel
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 79430 6450, USA
    Mol Cancer Ther 9:3164-74. 2010
  4. doi request reprint Initial testing of lenalidomide by the pediatric preclinical testing program
    C Patrick Reynolds
    Texas Tech University Health Sciences Center, Lubbock, Texas, USA
    Pediatr Blood Cancer 57:606-11. 2011

Research Grants

  1. ENHANCING ACTIVITY OF ALKYLATING AGENTS IN NEUROBLASTOMA
    Charles Reynolds; Fiscal Year: 2001
  2. ENHANCING ACTIVITY OF ALKYLATING AGENTS IN NEUROBLASTOMA
    CHARLES PATRICK REYNOLDS; Fiscal Year: 2010

Collaborators

Detail Information

Publications4

  1. doi request reprint Initial testing (stage 1) of the phosphatidylinositol 3' kinase inhibitor, SAR245408 (XL147) by the pediatric preclinical testing program
    C Patrick Reynolds
    Cancer Center, Cancer Center, Texas Tech University Health Sciences Center, Lubbock, Texas 79430 6450, USA
    Pediatr Blood Cancer 60:791-8. 2013
    ..However, less is known regarding the relevance of this pathway in pediatric cancers. Here we have evaluated SAR245408, a novel small molecule PI3K inhibitor, against childhood cancer cell lines and xenografts...
  2. pmc The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA
    Philipp Kapranov
    Helicos BioSciences Corporation, One Kendall Square, Building 700, Cambridge, MA 02139, USA
    BMC Biol 8:149. 2010
    ..For example, efforts to elucidate how non-coding RNAs (ncRNAs) regulate genome function will be compromised if that class of RNAs is dismissed as simply 'transcriptional noise'...
  3. pmc Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins
    Michael D Hadjidaniel
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 79430 6450, USA
    Mol Cancer Ther 9:3164-74. 2010
    ..Thus, combining 13-cis-RA with cytotoxic chemotherapy significantly reduced the cytotoxicity for neuroblastoma in vitro, mediated at least in part via the antiapoptotic Bcl-2 family of proteins...
  4. doi request reprint Initial testing of lenalidomide by the pediatric preclinical testing program
    C Patrick Reynolds
    Texas Tech University Health Sciences Center, Lubbock, Texas, USA
    Pediatr Blood Cancer 57:606-11. 2011
    ..On the basis of this varied pharmacological profile, lenalidomide is under investigation as a treatment for a range of oncologic indications...

Research Grants7

  1. ENHANCING ACTIVITY OF ALKYLATING AGENTS IN NEUROBLASTOMA
    Charles Reynolds; Fiscal Year: 2001
    ..TdT-labeling/flow cytometry and caspase activation. We anticipate that this research will contribute to the understanding of alkylator resistance in neuroblastoma and will result in more effective treatment modalities. ..
  2. ENHANCING ACTIVITY OF ALKYLATING AGENTS IN NEUROBLASTOMA
    CHARLES PATRICK REYNOLDS; Fiscal Year: 2010
    ....