Blanca I Restrepo

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Host-pathogen interactions in tuberculosis patients with type 2 diabetes mellitus
    Blanca I Restrepo
    UTHealth Houston, School of Public Health at Brownsville, 80 Fort Brown, Brownsville, Texas 78520, USA Electronic address
    Tuberculosis (Edinb) 93:S10-4. 2013
  2. pmc Cross-sectional assessment reveals high diabetes prevalence among newly-diagnosed tuberculosis cases
    Blanca I Restrepo
    School of Public Health in Brownsville, University of Texas Health Science Center at Houston, Brownsville, 78520, USA
    Bull World Health Organ 89:352-9. 2011
  3. pmc Systematic interpretation of molecular beacon polymerase chain reaction for identifying rpoB mutations in Mycobacterium tuberculosis isolates with mixed resistant and susceptible bacteria
    Diana I Gomez
    The University of Texas Health Science Center Houston, School of Public Health at Brownsville, Brownsville, TX 78520, USA
    Diagn Microbiol Infect Dis 67:37-46. 2010
  4. pmc Rapid DNA extraction for specific detection and quantitation of Mycobacterium tuberculosis DNA in sputum specimens using Taqman assays
    Diana I Gomez
    Division of Epidemiology, School of Public Health in Brownsville, University of Texas Health Science Center at Houston, 80 Fort Brown, SPH Bldg, Brownsville, Texas 78520, USA
    Tuberculosis (Edinb) 91:S43-8. 2011
  5. pmc Type 2 diabetes and multidrug-resistant tuberculosis
    Susan P Fisher-Hoch
    University of Texas School of Public Health Regional Campus, Brownsville, TX 78520, USA
    Scand J Infect Dis 40:888-93. 2008
  6. pmc Tuberculosis in poorly controlled type 2 diabetes: altered cytokine expression in peripheral white blood cells
    Blanca I Restrepo
    Division of Epidemiology, University of Texas Health Science Center at Houston, School of Public Health, University of Texas at Brownsville, 80 Fort Brown, SPH Bldg, Brownsville, TX 78520, USA
    Clin Infect Dis 47:634-41. 2008
  7. pmc Mycobacterial clearance from sputum is delayed during the first phase of treatment in patients with diabetes
    Blanca I Restrepo
    Division of Epidemiology, University of Texas School of Public Health, Brownsville, Texas 78520, USA
    Am J Trop Med Hyg 79:541-4. 2008
  8. pmc Reduced Mycobacterium tuberculosis association with monocytes from diabetes patients that have poor glucose control
    Diana I Gomez
    Division of Epidemiology, University of Texas Health Science Center at Houston, School of Public Health at Brownsville, 80 Fort Brown, SPH Bldg, Brownsville, TX 78520, USA
    Tuberculosis (Edinb) 93:192-7. 2013
  9. pmc Socioeconomic status and prevalence of obesity and diabetes in a Mexican American community, Cameron County, Texas, 2004-2007
    Susan P Fisher-Hoch
    Division of Epidemiology, University of Texas School of Public Health, Brownsville Campus, 80 Fort Brown, Brownsville, TX 78520, USA
    Prev Chronic Dis 7:A53. 2010
  10. pmc Association between tuberculosis and diabetes in the Mexican border and non-border regions of Texas
    Adriana Perez
    Division of Biostatistics, School of Public Health, The University of Texas at Houston Health Science Center, Brownsville, Texas 78520, USA
    Am J Trop Med Hyg 74:604-11. 2006

Collaborators

Detail Information

Publications16

  1. pmc Host-pathogen interactions in tuberculosis patients with type 2 diabetes mellitus
    Blanca I Restrepo
    UTHealth Houston, School of Public Health at Brownsville, 80 Fort Brown, Brownsville, Texas 78520, USA Electronic address
    Tuberculosis (Edinb) 93:S10-4. 2013
    ....
  2. pmc Cross-sectional assessment reveals high diabetes prevalence among newly-diagnosed tuberculosis cases
    Blanca I Restrepo
    School of Public Health in Brownsville, University of Texas Health Science Center at Houston, Brownsville, 78520, USA
    Bull World Health Organ 89:352-9. 2011
    ..To estimate the contribution of clinically-confirmed diabetes mellitus to tuberculosis (TB) rates in communities where both diseases are prevalent as a way to identify opportunities for TB prevention among diabetic patients...
  3. pmc Systematic interpretation of molecular beacon polymerase chain reaction for identifying rpoB mutations in Mycobacterium tuberculosis isolates with mixed resistant and susceptible bacteria
    Diana I Gomez
    The University of Texas Health Science Center Houston, School of Public Health at Brownsville, Brownsville, TX 78520, USA
    Diagn Microbiol Infect Dis 67:37-46. 2010
    ....
  4. pmc Rapid DNA extraction for specific detection and quantitation of Mycobacterium tuberculosis DNA in sputum specimens using Taqman assays
    Diana I Gomez
    Division of Epidemiology, School of Public Health in Brownsville, University of Texas Health Science Center at Houston, 80 Fort Brown, SPH Bldg, Brownsville, Texas 78520, USA
    Tuberculosis (Edinb) 91:S43-8. 2011
    ..Together, our protocol provides rapid, specific, inexpensive and quantitative detection of Mtb DNA in fresh or stored sputa making it a robust tool for prompt TB diagnosis, and with potential use for clinical and epidemiologic studies...
  5. pmc Type 2 diabetes and multidrug-resistant tuberculosis
    Susan P Fisher-Hoch
    University of Texas School of Public Health Regional Campus, Brownsville, TX 78520, USA
    Scand J Infect Dis 40:888-93. 2008
    ..In Texas, all but 3 of the T2DM patients with MDR TB were resistant at their first culture at the time of diagnosis. It is possible that impaired immunity in T2DM increases susceptibility to infection with resistant strains...
  6. pmc Tuberculosis in poorly controlled type 2 diabetes: altered cytokine expression in peripheral white blood cells
    Blanca I Restrepo
    Division of Epidemiology, University of Texas Health Science Center at Houston, School of Public Health, University of Texas at Brownsville, 80 Fort Brown, SPH Bldg, Brownsville, TX 78520, USA
    Clin Infect Dis 47:634-41. 2008
    ....
  7. pmc Mycobacterial clearance from sputum is delayed during the first phase of treatment in patients with diabetes
    Blanca I Restrepo
    Division of Epidemiology, University of Texas School of Public Health, Brownsville, Texas 78520, USA
    Am J Trop Med Hyg 79:541-4. 2008
    ....
  8. pmc Reduced Mycobacterium tuberculosis association with monocytes from diabetes patients that have poor glucose control
    Diana I Gomez
    Division of Epidemiology, University of Texas Health Science Center at Houston, School of Public Health at Brownsville, 80 Fort Brown, SPH Bldg, Brownsville, TX 78520, USA
    Tuberculosis (Edinb) 93:192-7. 2013
    ..These findings suggest an altered route of entry of the pathogen in DM patients that may influence the downstream activation of signaling pathways in the monocyte and the survival of mycobacteria...
  9. pmc Socioeconomic status and prevalence of obesity and diabetes in a Mexican American community, Cameron County, Texas, 2004-2007
    Susan P Fisher-Hoch
    Division of Epidemiology, University of Texas School of Public Health, Brownsville Campus, 80 Fort Brown, Brownsville, TX 78520, USA
    Prev Chronic Dis 7:A53. 2010
    ..We established a cohort on the United States-Mexico border to determine the prevalence of obesity and diabetes in this Mexican American population and to see whether minor economic advantages had any effect on health...
  10. pmc Association between tuberculosis and diabetes in the Mexican border and non-border regions of Texas
    Adriana Perez
    Division of Biostatistics, School of Public Health, The University of Texas at Houston Health Science Center, Brownsville, Texas 78520, USA
    Am J Trop Med Hyg 74:604-11. 2006
    ..82; 95% CI = 1.57-2.12) compared with non-border counties (OR(adj) = 1.51; 95% CI = 1.36-1.67)...
  11. pmc Phagocytosis via complement or Fc-gamma receptors is compromised in monocytes from type 2 diabetes patients with chronic hyperglycemia
    Blanca I Restrepo
    Division of Epidemiology, UTHealth Houston, School of Public Health at Brownsville, Brownsville, Texas, United States of America
    PLoS ONE 9:e92977. 2014
    ..Given that phagocytosis is linked to activation of effector mechanisms for bacterial killing, it is likely that this defect is one factor contributing to the higher susceptibility of DM2 patients to pathogens like M. tuberculosis. ..
  12. pmc Dipstick urinalysis for diabetes screening in TB patients
    Blanca I Restrepo
    Division of Epidemiology, School of Public Health in Brownsville, University of Texas Health Science Center at Houston, 80 Fort Brown, SPH Building, Brownsville, TX 78520, USA
    Int Health 5:157-9. 2013
    ..Given its low cost, the sensitivity of urine glucose dipsticks for diabetes screening in TB patients was assessed...
  13. pmc Selective enrichment and detection of mycobacterial DNA in paucibacillary specimens
    Blanca I Restrepo
    The University of Texas Health Science Center Houston, School of Public Health at Brownsville, Brownsville, Texas, United States
    J Microbiol Methods 67:220-9. 2006
    ..This tool is useful to study the pathophysiology of early pulmonary or occult tuberculosis, and for more rapid and accurate diagnosis in difficult to diagnose infections...
  14. pmc Differential expression of monocyte surface markers among TB patients with diabetes co-morbidity
    Samuel S Stew
    UT Health Houston, School of Public Health at Brownsville, 80 Fort Brown, Brownsville, Texas 78520, USA The Advisory Board Company, Austin, Texas, USA
    Tuberculosis (Edinb) 93:S78-82. 2013
    ..Given that DM2 patients are more likely to be older and obese, their monocytes are predicted to be altered in function in ways that affect their interaction with Mycobacterium tuberculosis. ..
  15. pmc Convergence of the tuberculosis and diabetes epidemics: renewal of old acquaintances
    Blanca I Restrepo
    Clin Infect Dis 45:436-8. 2007
  16. ncbi request reprint Serological screening for cysticercosis in mentally altered individuals
    Fernando Sanzón
    Universidad de Nariño, Centro de Estudios en Salud, San Juan de Pasto, Colombia
    Trop Med Int Health 7:532-8. 2002
    ..The data analysis indicated a weak association between the cases and a positive serology for neurocysticercosis (odds ratio > 2; P > 0.05). The lower education level of the cases influenced this association...

Research Grants1

  1. Rapid characterization of mycobacteria and drug resistance in paucibacillary TB
    BLANCA RESTREPO; Fiscal Year: 2007
    ..Funding of this R21 is critical to generate preliminary data that will strengthen future, more complex studies of the pathogenesis and evolution of MDR- TB in high-risk populations. ..