DOODIPALA REDDY

Summary

Affiliation: Texas A and M Health Science Center
Country: USA

Publications

  1. ncbi The pathophysiological and pharmacological basis of current drug treatment of migraine headache
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M University Health Science Center, 8447 State Highway 47, Medical Research and Education Building, Bryan, TX 77807, USA
    Expert Rev Clin Pharmacol 6:271-88. 2013
  2. ncbi Neuroendocrine aspects of catamenial epilepsy
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, 8447 State Highway 47, MREB Building, Bryan, TX 77807, USA Electronic address
    Horm Behav 63:254-66. 2013
  3. ncbi Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, Bryan, TX 77807, USA
    Epilepsy Behav 25:92-7. 2012
  4. ncbi A mouse kindling model of perimenstrual catamenial epilepsy
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M University Health Science Center, 8447 State Highway 47, MREB Building Room 1005, Bryan, TX 77807 3260, USA
    J Pharmacol Exp Ther 341:784-93. 2012
  5. ncbi Development and persistence of limbic epileptogenesis are impaired in mice lacking progesterone receptors
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, College Station, Texas 77843, USA
    J Neurosci 31:650-8. 2011
  6. ncbi Neurosteroids: endogenous role in the human brain and therapeutic potentials
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, College Station, TX, USA
    Prog Brain Res 186:113-37. 2010
  7. ncbi Disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843, USA
    Neuropharmacology 59:573-81. 2010
  8. ncbi The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, 228 Reynolds Medical Bldg, College Station, TX 77843 1114, USA
    J Pharmacol Exp Ther 334:1031-41. 2010
  9. ncbi Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model
    Doodipala S Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M System Health Science Center, College Station, TX 77843 1114, USA
    Epilepsy Res 89:254-60. 2010
  10. ncbi The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, 228 Reynolds Medical Building, College Station, TX 77843 1114, USA
    Epilepsy Res 85:1-30. 2009

Research Grants

  1. Progesterone Receptors and Seizure Susceptibility
    DOODIPALA REDDY; Fiscal Year: 2009
  2. Progesterone Receptors and Seizure Susceptibility
    Doodipala Samba Reddy; Fiscal Year: 2010

Collaborators

Detail Information

Publications12

  1. ncbi The pathophysiological and pharmacological basis of current drug treatment of migraine headache
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M University Health Science Center, 8447 State Highway 47, Medical Research and Education Building, Bryan, TX 77807, USA
    Expert Rev Clin Pharmacol 6:271-88. 2013
    ..New drugs with improved efficacy and reduced side effects are needed for effective treatment and prevention of migraine...
  2. ncbi Neuroendocrine aspects of catamenial epilepsy
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, 8447 State Highway 47, MREB Building, Bryan, TX 77807, USA Electronic address
    Horm Behav 63:254-66. 2013
    ..Neurosteroid analogs with favorable profile may be useful in the treatment of catamenial epilepsy...
  3. ncbi Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, Bryan, TX 77807, USA
    Epilepsy Behav 25:92-7. 2012
    ....
  4. ncbi A mouse kindling model of perimenstrual catamenial epilepsy
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M University Health Science Center, 8447 State Highway 47, MREB Building Room 1005, Bryan, TX 77807 3260, USA
    J Pharmacol Exp Ther 341:784-93. 2012
    ....
  5. ncbi Development and persistence of limbic epileptogenesis are impaired in mice lacking progesterone receptors
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, College Station, Texas 77843, USA
    J Neurosci 31:650-8. 2011
    ..The PR pathway may represent a unique target for preventing or retarding epileptogenesis in females...
  6. ncbi Neurosteroids: endogenous role in the human brain and therapeutic potentials
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, College Station, TX, USA
    Prog Brain Res 186:113-37. 2010
    ..Neurosteroidogenic agents that lack benzodiazepine-like side effects show promise in the treatment of anxiety and depression...
  7. ncbi Disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843, USA
    Neuropharmacology 59:573-81. 2010
    ....
  8. ncbi The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, 228 Reynolds Medical Bldg, College Station, TX 77843 1114, USA
    J Pharmacol Exp Ther 334:1031-41. 2010
    ....
  9. ncbi Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model
    Doodipala S Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M System Health Science Center, College Station, TX 77843 1114, USA
    Epilepsy Res 89:254-60. 2010
    ..1 mg/kg, s.c.). To the extent that amygdala kindling represents a model of mesial temporal lobe epilepsy, this study supports the utility of ganaxolone in the treatment of patients with temporal lobe seizures...
  10. ncbi The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy
    Doodipala Samba Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M Health Science Center, 228 Reynolds Medical Building, College Station, TX 77843 1114, USA
    Epilepsy Res 85:1-30. 2009
    ..Synthetic neurosteroids, which enhance the tonic GABA-A receptor function, might provide an effective approach for the catamenial epilepsy therapy without producing hormonal side effects...
  11. ncbi Neurosteroid replacement therapy for catamenial epilepsy
    Doodipala S Reddy
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M System Health Science Center, College Station, Texas 77843, USA
    Neurotherapeutics 6:392-401. 2009
    ..Positive allosteric modulatory neurosteroids and synthetic analogs such as ganaxolone may be administered to prevent catamenial seizure exacerbations, in what we call neurosteroid replacement therapy...
  12. ncbi The optimization of TaqMan real-time RT-PCR assay for transcriptional profiling of GABA-A receptor subunit plasticity
    Omkaram Gangisetty
    Department of Neuroscience and Experimental Therapeutics, College of Medicine, Texas A and M System Health Science Center, College Station, TX 77843 1114, USA
    J Neurosci Methods 181:58-66. 2009
    ....

Research Grants3

  1. Progesterone Receptors and Seizure Susceptibility
    DOODIPALA REDDY; Fiscal Year: 2009
    ....
  2. Progesterone Receptors and Seizure Susceptibility
    Doodipala Samba Reddy; Fiscal Year: 2010
    ....