Pulivarthi H Rao

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma
    Pulivarthi H Rao
    Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX, USA
    BMC Cancer 4:5. 2004
  2. ncbi request reprint Deletion of 1p32-p36 is the most frequent genetic change and poor prognostic marker in adenoid cystic carcinoma of the salivary glands
    Pulivarthi H Rao
    Texas Children s Cancer Center, Baylor College of Medicine, The University of Texas M D Anderson Cancer Center and Spectral Genomics, Houston, Texas, USA
    Clin Cancer Res 14:5181-7. 2008
  3. pmc Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcoma
    Xin Yan Lu
    Texas Children s Cancer Center, Baylor College of Medicine, 6621 Fannin Street, MC 3 3320, Houston, TX 77030, USA
    Mol Cancer Res 6:937-46. 2008
  4. pmc Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance
    Li Zhang
    Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Pathol 182:2048-57. 2013
  5. ncbi request reprint Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma
    Ching C Lau
    Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Genes Chromosomes Cancer 39:11-21. 2004
  6. pmc Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcoma
    Tsz Kwong Man
    Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX, USA
    BMC Cancer 4:45. 2004
  7. pmc Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8
    Massimiliano De Bortoli
    Texas Children s Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    BMC Cancer 6:223. 2006
  8. ncbi request reprint Comprehensive molecular cytogenetic characterization of cervical cancer cell lines
    Charles P Harris
    Laboratory of Molecular Cytogenetics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Genes Chromosomes Cancer 36:233-41. 2003
  9. pmc Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome
    Yoshitsugu Mitani
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 17:7003-14. 2011
  10. pmc Overexpression of Separase induces aneuploidy and mammary tumorigenesis
    Nenggang Zhang
    Department of Pediatric Hematology Oncology, Texas Children s Cancer Center, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 105:13033-8. 2008

Collaborators

Detail Information

Publications47

  1. pmc Chromosomal amplifications, 3q gain and deletions of 2q33-q37 are the frequent genetic changes in cervical carcinoma
    Pulivarthi H Rao
    Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX, USA
    BMC Cancer 4:5. 2004
    ..Therefore, genetic characterization is essential for understanding the biology and clinical heterogeneity in cervical cancer (CC)...
  2. ncbi request reprint Deletion of 1p32-p36 is the most frequent genetic change and poor prognostic marker in adenoid cystic carcinoma of the salivary glands
    Pulivarthi H Rao
    Texas Children s Cancer Center, Baylor College of Medicine, The University of Texas M D Anderson Cancer Center and Spectral Genomics, Houston, Texas, USA
    Clin Cancer Res 14:5181-7. 2008
    ..The purpose of this study is to identify prognostic factors other than tumor stage that can be used to predict the outcome of the patients with ACC...
  3. pmc Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcoma
    Xin Yan Lu
    Texas Children s Cancer Center, Baylor College of Medicine, 6621 Fannin Street, MC 3 3320, Houston, TX 77030, USA
    Mol Cancer Res 6:937-46. 2008
    ..These results indicate that CDC5L, a cell cycle regulator important for the G2-M transition, is the most likely candidate oncogene for the 6p12-p21 amplicon found in osteosarcoma...
  4. pmc Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance
    Li Zhang
    Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Pathol 182:2048-57. 2013
    ..These findings support the pathogenetic segregation of these entities and define novel chromosomal sites for future identification of biomarkers and therapeutic targets...
  5. ncbi request reprint Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma
    Ching C Lau
    Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Genes Chromosomes Cancer 39:11-21. 2004
    ....
  6. pmc Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcoma
    Tsz Kwong Man
    Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX, USA
    BMC Cancer 4:45. 2004
    ..Therefore, a better understanding of the underlying molecular genetic events leading to tumor initiation and progression could result in the identification of potential diagnostic and therapeutic targets...
  7. pmc Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8
    Massimiliano De Bortoli
    Texas Children s Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    BMC Cancer 6:223. 2006
    ..In the present study, we applied cytogenetic characterization to guide the identification of biologically significant genes from gene expression microarray profiles of medulloblastoma...
  8. ncbi request reprint Comprehensive molecular cytogenetic characterization of cervical cancer cell lines
    Charles P Harris
    Laboratory of Molecular Cytogenetics, Texas Children s Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Genes Chromosomes Cancer 36:233-41. 2003
    ..This comprehensive cytogenetic characterization of eight CC cell lines enhances their utility in experimental studies aimed at gene discovery and functional analysis...
  9. pmc Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome
    Yoshitsugu Mitani
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 17:7003-14. 2011
    ..To investigate the molecular genetic heterogeneity associated with the t(6:9) in adenoid cystic carcinoma (ACC) and correlate the findings with patient clinical outcome...
  10. pmc Overexpression of Separase induces aneuploidy and mammary tumorigenesis
    Nenggang Zhang
    Department of Pediatric Hematology Oncology, Texas Children s Cancer Center, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 105:13033-8. 2008
    ..These results collectively suggest that Separase is an oncogene, whose overexpression alone in mammary epithelial cells is sufficient to induce aneuploidy and tumorigenesis in a p53 mutant background...
  11. ncbi request reprint Clinical utility of array comparative genomic hybridization for detection of chromosomal abnormalities in pediatric acute lymphoblastic leukemia
    Karen R Rabin
    Department of Pediatric Hematology Oncology, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Blood Cancer 51:171-7. 2008
    ..Accurate detection of recurrent chromosomal abnormalities is critical to assign patients to risk-based therapeutic regimens for pediatric acute lymphoblastic leukemia (ALL)...
  12. doi request reprint Comprehensive analysis of the MYB-NFIB gene fusion in salivary adenoid cystic carcinoma: Incidence, variability, and clinicopathologic significance
    Yoshitsugu Mitani
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, 77030 4009, USA
    Clin Cancer Res 16:4722-31. 2010
    ....
  13. pmc Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D
    Robert C Castellino
    Department of Pediatrics, Texas Children s Cancer Center, Baylor College of Medicine, 6621 Fannin Street, MC 3 3320, Houston, TX 77030, USA
    J Neurooncol 86:245-56. 2008
    ..These results indicate that medulloblastoma express significant levels of WIP1 that modulate genotoxic responsiveness by negatively regulating p53...
  14. pmc A systems biology approach reveals common metastatic pathways in osteosarcoma
    Ricardo J Flores
    Texas Children s Cancer Center, Texas Children s Hospital, Houston, TX, USA
    BMC Syst Biol 6:50. 2012
    ..In this study, we used a systems biology approach to identify common metastatic pathways that are jointly supported by both mRNA and protein expression data in two distinct human metastatic OS models...
  15. ncbi request reprint Molecular cytogenetic applications in analysis of the cancer genome
    Pulivarthi H Rao
    Baylor College of Medicine, Texas Children s Cancer Center, Houston, USA
    Methods Mol Biol 383:165-85. 2007
    ..The opportunities to detect genetic alterations in cancer cells continue to evolve with the use of these methodologies both in diagnosis and research...
  16. ncbi request reprint Amplification of MGC2177, PLAG1, PSMC6P, and LYN in a malignant mixed tumor of salivary gland detected by cDNA microarray with tyramide signal amplification
    Yvonne T M Tsang
    Texas Children s Cancer Center, Cancer Genomics Group, MC3 3320, Department of Pediatrics, Baylor College of Medicine, 6621 Fannin Street, Houston, TX 77030, USA
    Cancer Genet Cytogenet 152:124-8. 2004
    ..2 approximately q13: MGC2177, PLAG1, PSMC6P, and LYN. The amplification was further validated with real-time quantitative polymerase chain reaction...
  17. pmc A handcuff model for the cohesin complex
    Nenggang Zhang
    Department of Pediatric Hematology Oncology, Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
    J Cell Biol 183:1019-31. 2008
    ..These data support a two-ring handcuff model for the cohesin complex, which is flexible enough to establish and maintain sister chromatid cohesion as well as ensure the fidelity of chromosome segregation in higher eukaryotes...
  18. doi request reprint Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells
    Yihui Fan
    Texas Children s Cancer Center, Baylor College of Medicine, Houston, TX, USA Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    J Pathol 232:75-86. 2014
    ....
  19. ncbi request reprint Comparative genomic hybridization for analysis of changes in DNA copy number in multiple myeloma
    Pulivarthi H Rao
    Texas Childrens Cancer Centre, Baylor College of Medicine, Houston TX, USA
    Methods Mol Med 113:71-83. 2005
    ..The detailed procedures for CGH, including DNA labeling, hybridization, fluorescence microscopy, digital image analysis, and data interpretation, as well as the limitations of CGH are discussed in this chapter...
  20. pmc Translocation t(6;14) as the sole chromosomal abnormality in adenoid cystic carcinoma of the base of tongue
    Diana Bell
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Head Neck Pathol 1:165-8. 2007
    ..This finding supports a critical role for this event in the development of this tumor. The implications of chromosome 6q translocation in this case and in previously reported adenoid cystic carcinomas are highlighted and discussed...
  21. doi request reprint t(3;8) as the sole chromosomal abnormality in a myoepithelial carcinoma ex pleomorphic adenoma: a putative progression event
    Diana Bell
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Head Neck 35:E181-3. 2013
    ..Carcinoma ex pleomorphic adenoma (Ca ex-PA) is defined as a carcinoma arising from a primary (de novo) or recurrent benign pleomorphic adenoma (PA)...
  22. ncbi request reprint Genomic segmental polymorphisms in inbred mouse strains
    Jiangzhen Li
    Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nat Genet 36:952-4. 2004
    ..The identification of these apparently common segmental polymorphisms suggests that these differences can contribute to genetic variability and pathologic susceptibility...
  23. ncbi request reprint Disruption of scaffold attachment factor B1 leads to TBX2 up-regulation, lack of p19ARF induction, lack of senescence, and cell immortalization
    Klaudia M Dobrzycka
    Department of Medicine, The Breast Center, Baylor College of Medicine, Houston, TX 77030, USA
    Cancer Res 66:7859-63. 2006
    ..SAFB1 loss also caused lack of contact inhibition, increased foci formation, and increased oncogene-induced anchorage-independent growth. These findings suggest that SAFB1 is a novel player in cellular immortalization and transformation...
  24. pmc A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo
    Litian Yu
    Laboratory of Molecular Neuro Oncology, Texas Children s Cancer Center, Texas Children s Hospital, Baylor College of Medicine, 6621 Fannin Street, MC 3 3320, Houston, TX 77030, USA
    Neuro Oncol 12:580-94. 2010
    ..This cell line and model will facilitate the biological studies and preclinical drug screenings for pediatric ependymomas...
  25. pmc piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies
    Pallavi V Raja Manuri
    Division of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Hum Gene Ther 21:427-37. 2010
    ..PB transposition for generating human T cells with redirected specificity to a desired target such as CD19 is a new genetic approach with therapeutic implications...
  26. pmc Amplification of the 3q26.3 locus is associated with progression to invasive cancer and is a negative prognostic factor in head and neck squamous cell carcinomas
    Bhuvanesh Singh
    Laboratory of Epithelial Cancer Biology, The Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Am J Pathol 161:365-71. 2002
    ..6; 95% confidence interval = 1.9 to 29.6). The findings suggest that the 3q copy number status is an important marker for tumor progression and prognostication in patients with head and neck squamous cell carcinoma...
  27. pmc Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure
    Bhuvanesh Singh
    Laboratory of Epithelial Cancer Biology, Biology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, USA
    BMC Genet 3:22. 2002
    ..We used comparative genomic hybridization (CGH) to screen for the genetic aberrations in 71 patients with head and neck squamous cell carcinoma and stratified the findings by the status of tobacco/alcohol exposure...
  28. ncbi request reprint Follicular variant of papillary thyroid carcinoma: genome-wide appraisal of a controversial entity
    Volkert B Wreesmann
    Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Genes Chromosomes Cancer 40:355-64. 2004
    ..Our findings suggest a stronger relationship between the FVPTC and FTA/FTC than previously appreciated and support further consideration of the current classification of thyroid neoplasms...
  29. ncbi request reprint Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes
    Veronique Bourdon
    Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 62:6218-23. 2002
    ..Combined array comparative genomic hybridization and array expression analysis is a valid approach for gene discovery in large chromosomal amplicons...
  30. ncbi request reprint Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma
    Guido B van den Broek
    Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Clin Cancer Res 13:4386-91. 2007
    ..To identify reliable predictors of chemoradiation resistance of advanced head and neck squamous cell carcinoma (HNSCC)...
  31. ncbi request reprint Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: identification of candidate amplified and overexpressed genes
    Gopeshwar Narayan
    Department of Pathology, Columbia University Medical Center, NY 10032, USA
    Genes Chromosomes Cancer 46:373-84. 2007
    ..These data, thus, form an important step toward the identification of biologically relevant genes in CC pathogenesis. This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat...
  32. ncbi request reprint Spectral karyotyping identifies new rearrangements, translocations, and clinical associations in diffuse large B-cell lymphoma
    Gouri Nanjangud
    Cell Biology Program, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Blood 99:2554-61. 2002
    ..These studies emphasize the value of SKY analysis for redefinition of chromosomal instability in DLBCL to enhance gene discovery as well as clinical correlation analysis...
  33. pmc p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas
    Bhuvanesh Singh
    Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Genes Dev 16:984-93. 2002
    ..Thus, p53 regulates cell survival by inhibiting the PI3K/AKT prosurvival signal independent of PTEN in epithelial tumors. This inhibition is required for p53-mediated apoptosis in malignant cells...
  34. pmc Genome-wide appraisal of thyroid cancer progression
    Volkert B Wreesmann
    Laboratory of Epithelial Cancer Biology, Head and Neck Service, New York, New York 10021, USA
    Am J Pathol 161:1549-56. 2002
    ..Our data suggests that the development of chromosomal instability underlies the progression to more aggressive phenotypes of thyroid cancer and sheds light on the possible genomic aberrations that may be selected for during this process...
  35. ncbi request reprint Relationship of XIST expression and responses of ovarian cancer to chemotherapy
    Kuan Chun Huang
    Laboratory of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cancer Ther 1:769-76. 2002
    ..Our data suggest that XIST expression may be a potential marker for chemotherapeutic responses in ovarian cancer...
  36. ncbi request reprint Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification
    Davide Ruggero
    Molecular Biology Program, Department of Pathology, Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute, 1275 York Avenue, New York, NY 10021, USA
    Science 299:259-62. 2003
    ..These results suggest that deregulated ribosome function is important in the initiation of DC, whereas telomere shortening may modify and/or exacerbate DC...
  37. ncbi request reprint Molecular determinants of tumor differentiation in papillary serous ovarian carcinoma
    Amir A Jazaeri
    Center for Cancer Research of the National Cancer Institute, Gaithersburg, Maryland, USA
    Mol Carcinog 36:53-9. 2003
    ..Dysregulation of centrosome function is one potential mechanistic link between genetic/epigenetic changes and the poorly differentiated phenotype in ovarian cancer...
  38. ncbi request reprint Genetic analysis identifies putative tumor suppressor sites at 2q35-q36.1 and 2q36.3-q37.1 involved in cervical cancer progression
    Gopeshwar Narayan
    Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Oncogene 22:3489-99. 2003
    ..Thus, these data identify frequent chromosomal amplifications in CC, and sites of TSGs at 2q35-q36.1 and 2q36.3-q37.1 that are critical in CC development...
  39. pmc The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability
    Michael Overholtzer
    Laboratory of Cancer Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:11547-52. 2003
    ..These results demonstrate that the inactivation of p53 in osteosarcomas directly by mutation versus indirectly by HDM2 amplification may have different cellular consequences with respect to the stability of the genome...
  40. ncbi request reprint Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud's syndrome: a case report emphasizing the cytological and cytogenetic findings
    Darshana N Jhala
    Department of Pathology, University of Alabama, Birmingham 35233, USA
    Hum Pathol 34:1354-7. 2003
    ..We are unaware of any previous reports of the cytogenetic findings in the tissue of this rare condition, and argue for the value of FNA in the evaluation of such patients under selected conditions...
  41. ncbi request reprint Overexpression of E2F-1 in lung and liver metastases of human colon cancer is associated with gene amplification
    Marian Iwamoto
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer Biol Ther 3:395-9. 2004
    ..In as much as TS is transcriptionally regulated by E2F-1, these results provide an explanation for the high levels of TS mRNA noted in some tumor samples...
  42. ncbi request reprint Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker
    Volkert B Wreesmann
    Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer Res 64:3780-9. 2004
    ..3; 95% confidence interval, 1.1-5.5; P = 0.03). Our data suggest that MUC1 dysregulation is associated with aggressive behavior of PTC and may serve as a prognostic marker and potential therapeutic target in this disease...
  43. ncbi request reprint Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck
    Volkert B Wreesmann
    Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    J Clin Oncol 22:3965-72. 2004
    ..The goal of this study was to identify chromosomal aberrations associated with poor outcome in patients with head and neck squamous cell carcinoma (HNSCC)...
  44. ncbi request reprint The p73 locus is commonly deleted in non-Hodgkin's lymphomas
    Archontoula Stoffel
    Laboratory for Cancer Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Leuk Res 28:1341-5. 2004
    ..Our results demonstrate a high proportion of p73 locus specific deletions in NHL and suggest that deletion of this locus may play a role in the progression of NHL...
  45. ncbi request reprint Identification of DNA copy number changes in microdissected serous ovarian cancer tissue using a cDNA microarray platform
    Hiroshi Tsuda
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Laboratory of Gynecologic Oncology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Harvard Medical School, BLI 447, 221 Longwood Avenue, Boston, MA 02115, USA
    Cancer Genet Cytogenet 155:97-107. 2004
    ..These results show the feasibility of using the cDNA array platform to identify changes in DNA and mRNA copy number simultaneously in microdissected tumor tissues...
  46. ncbi request reprint Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas
    Inderpal Sarkaria
    Laboratory of Epithelial Cancer Biology, Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Res 66:9437-44. 2006
    ..Collectively, these data suggest that SCCRO is a novel component of the HH signaling pathway involved in the malignant transformation of squamous cell lineage...
  47. ncbi request reprint Similar patterns of genomic alterations characterize primary mediastinal large-B-cell lymphoma and diffuse large-B-cell lymphoma
    Nallasivam Palanisamy
    Laboratory of Cancer Genetics, Cell Biology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Genes Chromosomes Cancer 33:114-22. 2002
    ..Based on these data, we conclude that PMLBCL is a distinct entity among GC-derived high-grade DLBCLs...