V N Potaman

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. ncbi request reprint Stabilization of intramolecular triple/single-strand structure by cationic peptides
    V N Potaman
    Institute of Biosciences and Technology, Texas A and M University, Houston 77030 3303, USA
    Biochemistry 37:12952-61. 1998
  2. pmc Overcoming a barrier for DNA polymerization in triplex-forming sequences
    V N Potaman
    Institute of Biosciences and Technology, The Texas A and M University System Health Science Center, 2121 West Holcombe Boulevard, Houston, TX 77030, USA
    Nucleic Acids Res 27:e5. 1999
  3. ncbi request reprint Applications of triple-stranded nucleic acid structures to DNA purification, detection and analysis
    Vladimir N Potaman
    Institute of Biosciences and Technology, Texas A and M University Health Sciences Center, Houston 77030 3303, USA
    Expert Rev Mol Diagn 3:481-96. 2003
  4. ncbi request reprint Site-specific labeling of supercoiled DNA at the A+T rich sequences
    Vladimir N Potaman
    Center for Genome Research, Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, Houston, Texas 77030 3303, USA
    Biochemistry 41:13198-206. 2002
  5. ncbi request reprint Involvement of the nucleotide excision repair protein UvrA in instability of CAG*CTG repeat sequences in Escherichia coli
    E A Oussatcheva
    Institute of Biosciences and Technology, Texas A and M University System Health Science Center, Houston, Texas 77030, USA
    J Biol Chem 276:30878-84. 2001
  6. pmc Length-dependent structure formation in Friedreich ataxia (GAA)n*(TTC)n repeats at neutral pH
    V N Potaman
    Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, Houston, TX 77030, USA
    Nucleic Acids Res 32:1224-31. 2004
  7. ncbi request reprint Unpaired structures in SCA10 (ATTCT)n.(AGAAT)n repeats
    Vladimir N Potaman
    Laboratory of DNA Structure and Function, Center for Genome Research, Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, Houston, TX 77030 3303, USA
    J Mol Biol 326:1095-111. 2003
  8. pmc Site-specific labeling of supercoiled DNA
    Alexander Y Lushnikov
    Department of Pharmaceutical Sciences, College of Pharmacy University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, NE 68198 6025, USA
    Nucleic Acids Res 34:e111. 2006
  9. pmc DNA strand arrangement within the SfiI-DNA complex: atomic force microscopy analysis
    Alexander Y Lushnikov
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198 6025, USA
    Biochemistry 45:152-8. 2006
  10. ncbi request reprint Specific binding of poly(ADP-ribose) polymerase-1 to cruciform hairpins
    Vladimir N Potaman
    Institute of Biosciences and Technology, Texas A and M University System Health Science Center, 2121 W Holcombe Blvd, Houston, TX 77030, USA
    J Mol Biol 348:609-15. 2005

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Stabilization of intramolecular triple/single-strand structure by cationic peptides
    V N Potaman
    Institute of Biosciences and Technology, Texas A and M University, Houston 77030 3303, USA
    Biochemistry 37:12952-61. 1998
    ..It is possible that Arg-rich peptides interact with the unpaired single strand in H-DNA and stabilize its unpaired conformation...
  2. pmc Overcoming a barrier for DNA polymerization in triplex-forming sequences
    V N Potaman
    Institute of Biosciences and Technology, The Texas A and M University System Health Science Center, 2121 West Holcombe Boulevard, Houston, TX 77030, USA
    Nucleic Acids Res 27:e5. 1999
    ..The described approach is potentially useful for sequencing and analysis of chemical adducts and point mutations in a variety of sequences prone to the formation of folded structures, such as long hairpins and quadruplexes...
  3. ncbi request reprint Applications of triple-stranded nucleic acid structures to DNA purification, detection and analysis
    Vladimir N Potaman
    Institute of Biosciences and Technology, Texas A and M University Health Sciences Center, Houston 77030 3303, USA
    Expert Rev Mol Diagn 3:481-96. 2003
    ..Adaptations of triplex methodology to molecular diagnostics (DNA purification, detection and analysis) are reviewed in greater detail...
  4. ncbi request reprint Site-specific labeling of supercoiled DNA at the A+T rich sequences
    Vladimir N Potaman
    Center for Genome Research, Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, Houston, Texas 77030 3303, USA
    Biochemistry 41:13198-206. 2002
    ..Site-specific oligonucleotide reactions with DNA may also have application in biotechnology and gene therapy...
  5. ncbi request reprint Involvement of the nucleotide excision repair protein UvrA in instability of CAG*CTG repeat sequences in Escherichia coli
    E A Oussatcheva
    Institute of Biosciences and Technology, Texas A and M University System Health Science Center, Houston, Texas 77030, USA
    J Biol Chem 276:30878-84. 2001
    ..These results imply a more comprehensive role for UvrA, in addition to the recognition of DNA damage, in maintaining the integrity of the genome...
  6. pmc Length-dependent structure formation in Friedreich ataxia (GAA)n*(TTC)n repeats at neutral pH
    V N Potaman
    Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, Houston, TX 77030, USA
    Nucleic Acids Res 32:1224-31. 2004
    ..At the premutation repeat length (n = 42) and higher negative supercoiling, the formation of a single H-DNA structure becomes less favorable and the data are consistent with the formation of a bi-triplex structure...
  7. ncbi request reprint Unpaired structures in SCA10 (ATTCT)n.(AGAAT)n repeats
    Vladimir N Potaman
    Laboratory of DNA Structure and Function, Center for Genome Research, Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, Houston, TX 77030 3303, USA
    J Mol Biol 326:1095-111. 2003
    ..A model is proposed in which unscheduled or aberrant DNA replication is a critical step in the expansion mutation...
  8. pmc Site-specific labeling of supercoiled DNA
    Alexander Y Lushnikov
    Department of Pharmaceutical Sciences, College of Pharmacy University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, NE 68198 6025, USA
    Nucleic Acids Res 34:e111. 2006
    ..The complex is relatively stable at low and high pH (pH 5 and 9) making the developed approach attractive for use at conditions requiring the pH change...
  9. pmc DNA strand arrangement within the SfiI-DNA complex: atomic force microscopy analysis
    Alexander Y Lushnikov
    Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198 6025, USA
    Biochemistry 45:152-8. 2006
    ..This suggests no preferential orientation of the DNA cognate site within the complex, suggesting that the central part of the DNA binding site does not form strong sequence specific contacts with the protein...
  10. ncbi request reprint Specific binding of poly(ADP-ribose) polymerase-1 to cruciform hairpins
    Vladimir N Potaman
    Institute of Biosciences and Technology, Texas A and M University System Health Science Center, 2121 W Holcombe Blvd, Houston, TX 77030, USA
    J Mol Biol 348:609-15. 2005
    ..Furthermore, our data indicate that PARP-1 can interact with the gene regulatory sequences by binding to the promoter-localized cruciforms...
  11. ncbi request reprint Regulation of poly(ADP-ribose) polymerase-1 by DNA structure-specific binding
    Irina Lonskaya
    Department of Radiation Medicine, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D C 20057, USA
    J Biol Chem 280:17076-83. 2005
    ..These data suggest a link between PARP-1 binding to non-B DNA structures in genome and its function in the dynamics of local modulation of chromatin structure in the normal physiology of the cell...
  12. pmc Interaction of the Zalpha domain of human ADAR1 with a negatively supercoiled plasmid visualized by atomic force microscopy
    Alexander Y Lushnikov
    School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA
    Nucleic Acids Res 32:4704-12. 2004
    ..These results indicate that Zalpha(ADAR1) binding facilities the B-to-Z transition and provides additional support to the model that Z-DNA binding proteins may regulate biological processes through structure-specific recognition...
  13. ncbi request reprint Supercoiling-induced DNA bending
    Jeffrey W Pavlicek
    School of Life Sciences, Arizona State University, Tempe, Arizona 85287, USA
    Biochemistry 43:10664-8. 2004
    ..This is consistent with increased helical distortion at an apical bend...
  14. ncbi request reprint Influence of global DNA topology on cruciform formation in supercoiled DNA
    Elena A Oussatcheva
    Center for Genome Research, Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, 2121 W Holcombe Blvd, Houston, TX 77030, USA
    J Mol Biol 338:735-43. 2004
    ..As structural transitions can be involved in biological processes, localization of alternative conformation-forming sequences to specific locations within a domain provides an additional means for gene regulation...
  15. ncbi request reprint Triplet repeat DNA structures and human genetic disease: dynamic mutations from dynamic DNA
    Richard R Sinden
    Laboratory of DNA Structure and Mutagenesis, Center for Genome Research, Institute of Biosciences and Technology, Texas A and M University System Health Sciences Center, 2121 West Holcombe Blvd, Houston, TX 77030 3303, USA
    J Biosci 27:53-65. 2002
    ..The remarkable stability of slipped strand DNA may, in part, be due to loop-loop interactions facilitated by the sequence complementarity of the loops and the dynamic structure of three-way junctions formed at the loop-outs...
  16. ncbi request reprint Intersegmental interactions in supercoiled DNA: atomic force microscope study
    Luda S Shlyakhtenko
    Department of Microbiology, Arizona State University, Tempe, AZ 85287, USA
    Ultramicroscopy 97:263-70. 2003
    ..Implications of the observed effect for understanding DNA compaction in the cell and for regulation DNA transactions via interaction of distantly separated DNA regions are discussed...
  17. ncbi request reprint Slipped strand DNA structures
    Richard R Sinden
    Laboratory of DNA Structure and Mutagenesis, Department of Biological Sciences, Florida Institute of Technology, Melbourne, FL 32901 6975, USA
    Front Biosci 12:4788-99. 2007
    ..This alternative DNA structure, or a similar slipped intermediate DNA that may form during DNA replication or repair, may be a causative factor in the instability of the DNA sequences that can form these structures...
  18. ncbi request reprint Transcriptional repression by binding of poly(ADP-ribose) polymerase to promoter sequences
    Viatcheslav A Soldatenkov
    Department of Radiation Medicine, Georgetown University Medical Center, Washington, DC 20007, USA
    J Biol Chem 277:665-70. 2002
    ..These data provide support for PARP protein as a potent regulator of transcription including down-regulation of its own promoter...