J L Pool

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. doi request reprint The role of baseline blood pressure in guiding treatment choice: a secondary analysis of the use of valsartan/hydrochlorothiazide as initial therapy in hypertensive adults in a randomized, double-blind, placebo-controlled trial
    James L Pool
    Center for Experimental Therapeutics, Baylor College of Medicine Faculty Center, 1709 Dryden Road, Suite 632, Houston, TX 77030, USA
    Clin Drug Investig 29:791-802. 2009
  2. ncbi request reprint Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension
    J L Pool
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Hypertens 11:462-70. 1998
  3. ncbi request reprint Clinical significance of alpha1-adrenoceptor selectivity in the management of benign prostatic hyperplasia
    J L Pool
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Int Urol Nephrol 33:407-12. 2001
  4. ncbi request reprint Is it time to move to multidrug combinations?
    James L Pool
    Departments of Medicine and Pharmacology, Center for Experimental Therapeutics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Hypertens 16:36S-40S. 2003
  5. ncbi request reprint Comparison of valsartan/hydrochlorothiazide combination therapy at doses up to 320/25 mg versus monotherapy: a double-blind, placebo-controlled study followed by long-term combination therapy in hypertensive adults
    James L Pool
    Center for Experimental Therapeutics, Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Ther 29:61-73. 2007
  6. ncbi request reprint Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan
    James L Pool
    Center for Experimental Therapeutics, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hypertens 20:11-20. 2007
  7. ncbi request reprint Use of the factorial design and quadratic response surface models to evaluate the fosinopril and hydrochlorothiazide combination therapy in hypertension
    J L Pool
    Section on Hypertension and Clinical Pharmacology, Baylor College of Medicine, Houston, Texas, USA
    Am J Hypertens 10:117-23. 1997
  8. ncbi request reprint Prolonged fenoldopam infusions in patients with mild to moderate hypertension: pharmacodynamic and pharmacokinetic effects
    A A Taylor
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Hypertens 12:906-14. 1999
  9. ncbi request reprint Combined terazosin and verapamil therapy in essential hypertension. Hemodynamic and pharmacokinetic interactions
    M L Lenz
    Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Am J Hypertens 8:133-45. 1995
  10. ncbi request reprint Direct renin inhibition: focus on aliskiren
    James L Pool
    Baylor College of Medicine, Houston, TX 77030, USA
    J Manag Care Pharm 13:21-33. 2007

Detail Information

Publications12

  1. doi request reprint The role of baseline blood pressure in guiding treatment choice: a secondary analysis of the use of valsartan/hydrochlorothiazide as initial therapy in hypertensive adults in a randomized, double-blind, placebo-controlled trial
    James L Pool
    Center for Experimental Therapeutics, Baylor College of Medicine Faculty Center, 1709 Dryden Road, Suite 632, Houston, TX 77030, USA
    Clin Drug Investig 29:791-802. 2009
    ..The objective of this study was to evaluate the role of baseline BP as a determinant of systolic BP (SBP) and treatment outcome to assist in the choice of initial therapy...
  2. ncbi request reprint Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension
    J L Pool
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Hypertens 11:462-70. 1998
    ..Withdrawal of irbesartan did not result in rebound hypertension or adverse events. Thus, once-daily irbesartan is both an effective and safe antihypertensive agent for the treatment of mild-to-moderate hypertension...
  3. ncbi request reprint Clinical significance of alpha1-adrenoceptor selectivity in the management of benign prostatic hyperplasia
    J L Pool
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Int Urol Nephrol 33:407-12. 2001
    ....
  4. ncbi request reprint Is it time to move to multidrug combinations?
    James L Pool
    Departments of Medicine and Pharmacology, Center for Experimental Therapeutics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Hypertens 16:36S-40S. 2003
    ..Knowing how specific combinations can be used effectively will be an important component of the treatment strategy for hypertension...
  5. ncbi request reprint Comparison of valsartan/hydrochlorothiazide combination therapy at doses up to 320/25 mg versus monotherapy: a double-blind, placebo-controlled study followed by long-term combination therapy in hypertensive adults
    James L Pool
    Center for Experimental Therapeutics, Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Ther 29:61-73. 2007
    ..Given the lifelong nature of hypertension, there is a need to evaluate the long-term efficacy and tolerability of higher doses of combination anti-hypertensive therapies...
  6. ncbi request reprint Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan
    James L Pool
    Center for Experimental Therapeutics, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Hypertens 20:11-20. 2007
    ..We investigated the blood pressure (BP)-lowering effects of the oral direct renin inhibitor aliskiren, alone or in combination with the angiotensin receptor blocker valsartan...
  7. ncbi request reprint Use of the factorial design and quadratic response surface models to evaluate the fosinopril and hydrochlorothiazide combination therapy in hypertension
    J L Pool
    Section on Hypertension and Clinical Pharmacology, Baylor College of Medicine, Houston, Texas, USA
    Am J Hypertens 10:117-23. 1997
    ..This study of combination agents for hypertension using a factorial design with QRSM accurately predicts dose responses and is a valuable clinical trial methodology...
  8. ncbi request reprint Prolonged fenoldopam infusions in patients with mild to moderate hypertension: pharmacodynamic and pharmacokinetic effects
    A A Taylor
    Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Hypertens 12:906-14. 1999
    ..The pharmacodynamic effects of the drug are best predicted by pharmacokinetics of racemic and R-fenoldopam...
  9. ncbi request reprint Combined terazosin and verapamil therapy in essential hypertension. Hemodynamic and pharmacokinetic interactions
    M L Lenz
    Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Am J Hypertens 8:133-45. 1995
    ..The orthostasis seen in some patients appears to be due to the combined vasodilatory effects rather than negative ionotropic or chronotropic effects...
  10. ncbi request reprint Direct renin inhibition: focus on aliskiren
    James L Pool
    Baylor College of Medicine, Houston, TX 77030, USA
    J Manag Care Pharm 13:21-33. 2007
    ..Aliskiren is the first direct renin inhibitor (DRI) to be approved by the U.S. Food and Drug Administration and the European Medicines Agency for treating hypertension...
  11. ncbi request reprint Clinical pharmacology of antihypertensive therapy
    Addison A Taylor
    Section on Hypertension and Clinical Pharmacology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Semin Nephrol 25:215-26. 2005
    ....
  12. ncbi request reprint The editor's roundtable: concurrent hypertension and dyslipidemia
    Vincent E Friedewald
    University of Texas Health Sciences Center at Houston, Houston, TX, USA
    Am J Cardiol 99:134-44. 2007