Jianwu Pei

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. pmc Toll-like receptors are critical for clearance of Brucella and play different roles in development of adaptive immunity following aerosol challenge in mice
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University, College Station TX, USA
    Front Cell Infect Microbiol 2:115. 2012
  2. pmc Mariner mutagenesis of Brucella melitensis reveals genes with previously uncharacterized roles in virulence and survival
    Qingmin Wu
    Department of Preventive Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China
    BMC Microbiol 6:102. 2006
  3. pmc Cytotoxicity in macrophages infected with rough Brucella mutants is type IV secretion system dependent
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University, College Station, TX 77843 4467, USA
    Infect Immun 76:30-7. 2008
  4. pmc Evidence of Brucella abortus OPS dictating uptake and restricting NF-kappaB activation in murine macrophages
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University and Texas Agricultural Experiment Station, College Station, TX 77843 4467, USA
    Microbes Infect 10:582-90. 2008
  5. pmc Immunogenic and invasive properties of Brucella melitensis 16M outer membrane protein vaccine candidates identified via a reverse vaccinology approach
    Gabriel Gomez
    Department of Veterinary Pathobiology, Texas A and M University, College Station, Texas, United States of America
    PLoS ONE 8:e59751. 2013
  6. doi request reprint In vitro mutagenesis of Brucella species
    Thomas A Ficht
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX, USA
    Methods Mol Biol 634:15-35. 2010
  7. pmc Brucella dissociation is essential for macrophage egress and bacterial dissemination
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University and Texas Agricultural Experiment Station College Station, TX, USA
    Front Cell Infect Microbiol 4:23. 2014
  8. ncbi request reprint Specific antibody secreting cells from chickens can be detected by three days and memory B cells by three weeks post-infection with the avian respiratory coronavirus
    Jianwu Pei
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843 4467, USA
    Dev Comp Immunol 29:153-60. 2005
  9. pmc Brucella abortus rough mutants induce macrophage oncosis that requires bacterial protein synthesis and direct interaction with the macrophage
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University, College Station, TX 77843 4467, USA
    Infect Immun 74:2667-75. 2006

Collaborators

Detail Information

Publications9

  1. pmc Toll-like receptors are critical for clearance of Brucella and play different roles in development of adaptive immunity following aerosol challenge in mice
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University, College Station TX, USA
    Front Cell Infect Microbiol 2:115. 2012
    ..In addition, although TLR4 and TLR2 contribute little to control of spleen infection, a significant contribution to clearance of lung infection is described...
  2. pmc Mariner mutagenesis of Brucella melitensis reveals genes with previously uncharacterized roles in virulence and survival
    Qingmin Wu
    Department of Preventive Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China
    BMC Microbiol 6:102. 2006
    ..melitensis genome. Conjugation was performed efficiently and rapidly in less than one generation in order to minimize the formation of siblings while assuring the highest level of genome coverage...
  3. pmc Cytotoxicity in macrophages infected with rough Brucella mutants is type IV secretion system dependent
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University, College Station, TX 77843 4467, USA
    Infect Immun 76:30-7. 2008
    ..Taken together, these results demonstrate that Brucella cytotoxicity in macrophages is T4SS dependent...
  4. pmc Evidence of Brucella abortus OPS dictating uptake and restricting NF-kappaB activation in murine macrophages
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University and Texas Agricultural Experiment Station, College Station, TX 77843 4467, USA
    Microbes Infect 10:582-90. 2008
    ..These results provide evidence that the presence of B. abortus OPS dictates the interactions between Brucella and specific cell surface receptors minimizing macrophage activation and enhancing Brucella survival and/or persistence...
  5. pmc Immunogenic and invasive properties of Brucella melitensis 16M outer membrane protein vaccine candidates identified via a reverse vaccinology approach
    Gabriel Gomez
    Department of Veterinary Pathobiology, Texas A and M University, College Station, Texas, United States of America
    PLoS ONE 8:e59751. 2013
    ..Studies to assess immunogenicity and protective efficacy of individual proteins in the mouse are currently underway...
  6. doi request reprint In vitro mutagenesis of Brucella species
    Thomas A Ficht
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX, USA
    Methods Mol Biol 634:15-35. 2010
    ..Toward this goal, this chapter describes current approaches used to mutagenize Brucella spp...
  7. pmc Brucella dissociation is essential for macrophage egress and bacterial dissemination
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University and Texas Agricultural Experiment Station College Station, TX, USA
    Front Cell Infect Microbiol 4:23. 2014
    ..Taken together, these results demonstrate that Brucella-induced cytotoxicity is critical for Brucella egress and dissemination. ..
  8. ncbi request reprint Specific antibody secreting cells from chickens can be detected by three days and memory B cells by three weeks post-infection with the avian respiratory coronavirus
    Jianwu Pei
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843 4467, USA
    Dev Comp Immunol 29:153-60. 2005
    ..i. ELISPOT detection of primary B cells could be useful in the early detection of infection following infection with respiratory coronaviruses...
  9. pmc Brucella abortus rough mutants induce macrophage oncosis that requires bacterial protein synthesis and direct interaction with the macrophage
    Jianwu Pei
    Department of Veterinary Pathobiology, Texas A and M University, College Station, TX 77843 4467, USA
    Infect Immun 74:2667-75. 2006
    ..In conclusion, Brucella rough mutant infection induces necrotic and oncotic macrophage cell death that requires bacterial protein synthesis and direct interaction of bacteria with the target cells...