SUSAN LYNNE PAYNE
Affiliation: Texas A and M University
- Birds and bornavirusesSusan L Payne
Department of Veterinary Pathobiology, Texas A and M University, College of Veterinary Medicine and Biomedical Sciences, College Station, 77843, USA
Anim Health Res Rev 13:145-56. 2012....
- Influence of long terminal repeat and env on the virulence phenotype of equine infectious anemia virusSusan L Payne
Department of Veterinary Pathobiology, Texas A and M University, College Station, Texas 77843 4467, USA
J Virol 78:2478-85. 2004..All chimeric clones replicated in primary equine monocyte-derived macrophages, and there was no apparent correlation between macrophage tropism and virulence phenotype...
- Virulence determinants of equine infectious anemia virusSusan L Payne
Department of Pathobiology, College of Veterinary Medicine, Texas A and M University, 4467 TAMU, College Station, TX 77843 4467, USA
Curr HIV Res 8:66-72. 2010..The V6 region of the viral env protein is an example of one identified region that may interact with the ELR-1 receptor in an important way and we are currently identifying S2 protein motifs required for disease expression...
- Unusual and severe lesions of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) acting as healthy carriers of avian bornavirus (ABV) and subsequently infected with a virulent strain of ABVS Payne
Department of Veterinary Pathobiology, Texas A and M University, College Station, TX, USA
Avian Pathol 40:15-22. 2011..Prior infection with ABV did not therefore confer significant immunity on these birds, and may have resulted in increased disease severity following challenge...
- Detection and characterization of a distinct bornavirus lineage from healthy Canada geese (Branta canadensis)Susan Payne
Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, MS 4467, Texas A and M University, College Station, TX 77843, USA
J Virol 85:12053-6. 2011..Phylogenetic analyses placed goose isolates in an independent cluster, and more notably, important regulatory sequences present in Borna disease virus but lacking in psittacine ABVs were present in goose isolates...
- The S2 accessory gene of equine infectious anemia virus is essential for expression of disease in poniesAngela J Fagerness
Department of Public Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606 8401, USA
Virology 349:22-30. 2006..0 logs at 15 days post-infection. The S2 deleted virus failed to produce any detectable clinical signs during a 5-month observation period. These results demonstrate that S2 gene expression is essential for disease expression of EIAV...
- EIAV S2 enhances pro-inflammatory cytokine and chemokine response in infected macrophagesLina Covaleda
Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, MS4467, College Station, TX 77843 4467, USA
Virology 397:217-23. 2010..Taken together, these results may help explain the effect of cytokine and chemokine dysregulation in EIAV pathogenesis and suggest a role of S2 in optimizing the host cell environment to promote viral dissemination and replication...
- Validation of quantitative polymerase chain reaction assays for measuring cytokine expression in equine macrophagesCharlotte A Allen
Department of Veterinary Pathobiology, Texas A and M University, MS 4467, College Station, TX 77843 4467, USA
J Immunol Methods 328:59-69. 2007..The primers and probes have been rigorously analyzed, and we demonstrate that they are specific for the desired genes, have a high amplification efficiency and the assays are highly reproducible...
- Identification of cellular proteins interacting with equine infectious anemia virus S2 proteinLina Covaleda
Department of Pathobiology, Texas A and M University, Texas Veterinary Medical College, MS4467, College Station, TX 77843 4467, USA
Virus Res 151:235-9. 2010..The roles of these cellular proteins during EIAV infection have not been determined...
- Lentiviral Diseases: EIAV PathogenesisSUSAN LYNNE PAYNE; Fiscal Year: 2010....
- EVOLUTION OF VIRULENCE OF EQUINE INFECTIOUS ANEMIA VIRUSSusan Payne; Fiscal Year: 2002..The EIAV system provides an excellent and tractable experimental model for study of evolutionary change in retroviruses, and for understanding the evolution and determinants of virulence. ..