Research Topics
| SUSAN LYNNE PAYNESummaryAffiliation: Texas A and M University Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Birds and bornavirusesSusan L Payne
Department of Veterinary Pathobiology, Texas A and M University, College of Veterinary Medicine and Biomedical Sciences, College Station, 77843, USA
Anim Health Res Rev 13:145-56. 2012....
Influence of long terminal repeat and env on the virulence phenotype of equine infectious anemia virusSusan L Payne
Department of Veterinary Pathobiology, Texas A and M University, College Station, Texas 77843 4467, USA
J Virol 78:2478-85. 2004..All chimeric clones replicated in primary equine monocyte-derived macrophages, and there was no apparent correlation between macrophage tropism and virulence phenotype...
Virulence determinants of equine infectious anemia virusSusan L Payne
Department of Pathobiology, College of Veterinary Medicine, Texas A and M University, 4467 TAMU, College Station, TX 77843 4467, USA
Curr HIV Res 8:66-72. 2010..The V6 region of the viral env protein is an example of one identified region that may interact with the ELR-1 receptor in an important way and we are currently identifying S2 protein motifs required for disease expression...
Unusual and severe lesions of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) acting as healthy carriers of avian bornavirus (ABV) and subsequently infected with a virulent strain of ABVS Payne
Department of Veterinary Pathobiology, Texas A and M University, College Station, TX, USA
Avian Pathol 40:15-22. 2011..Prior infection with ABV did not therefore confer significant immunity on these birds, and may have resulted in increased disease severity following challenge...
Detection and characterization of a distinct bornavirus lineage from healthy Canada geese (Branta canadensis)Susan Payne
Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, MS 4467, Texas A and M University, College Station, TX 77843, USA
J Virol 85:12053-6. 2011..Phylogenetic analyses placed goose isolates in an independent cluster, and more notably, important regulatory sequences present in Borna disease virus but lacking in psittacine ABVs were present in goose isolates...
The S2 accessory gene of equine infectious anemia virus is essential for expression of disease in poniesAngela J Fagerness
Department of Public Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606 8401, USA
Virology 349:22-30. 2006..0 logs at 15 days post-infection. The S2 deleted virus failed to produce any detectable clinical signs during a 5-month observation period. These results demonstrate that S2 gene expression is essential for disease expression of EIAV...
EIAV S2 enhances pro-inflammatory cytokine and chemokine response in infected macrophagesLina Covaleda
Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, MS4467, College Station, TX 77843 4467, USA
Virology 397:217-23. 2010..Taken together, these results may help explain the effect of cytokine and chemokine dysregulation in EIAV pathogenesis and suggest a role of S2 in optimizing the host cell environment to promote viral dissemination and replication...
Validation of quantitative polymerase chain reaction assays for measuring cytokine expression in equine macrophagesCharlotte A Allen
Department of Veterinary Pathobiology, Texas A and M University, MS 4467, College Station, TX 77843 4467, USA
J Immunol Methods 328:59-69. 2007..The primers and probes have been rigorously analyzed, and we demonstrate that they are specific for the desired genes, have a high amplification efficiency and the assays are highly reproducible...
Identification of cellular proteins interacting with equine infectious anemia virus S2 proteinLina Covaleda
Department of Pathobiology, Texas A and M University, Texas Veterinary Medical College, MS4467, College Station, TX 77843 4467, USA
Virus Res 151:235-9. 2010..The roles of these cellular proteins during EIAV infection have not been determined...
Research Grants
- Lentiviral Diseases: EIAV PathogenesisSUSAN LYNNE PAYNE; Fiscal Year: 2010....
- Lentiviral Diseases: EIAV PathogenesisSusan Payne; Fiscal Year: 2009....
- Lentiviral Diseases: EIAV PathogenesisSusan Payne; Fiscal Year: 2007..abstract_text> ..
- Lentiviral Diseases: EIAV PathogenesisSusan Payne; Fiscal Year: 2007....
- EVOLUTION OF VIRULENCE OF EQUINE INFECTIOUS ANEMIA VIRUSSusan Payne; Fiscal Year: 2002..The EIAV system provides an excellent and tractable experimental model for study of evolutionary change in retroviruses, and for understanding the evolution and determinants of virulence. ..
