Alan R Parrish

Summary

Affiliation: Texas A and M Health Science Center
Country: USA

Publications

  1. pmc Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase
    Alan R Parrish
    Department of Systems Biology and Translational Medicine, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843, USA
    Cell Biol Toxicol 25:217-25. 2009
  2. ncbi request reprint Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney
    Adebayo D Akintola
    Department of Systems Biology and Translational Medicine, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Am J Physiol Renal Physiol 294:F170-6. 2008
  3. ncbi request reprint Ischemia-induced cleavage of cadherins in NRK cells is not sufficient for beta-catenin transcriptional activity
    Gang Chen
    Department of Systems Biology and Translational Medicine, College of Medicine, Texas A and M University System Health Science Center, Texas, USA
    Cell Commun Adhes 14:111-23. 2007
  4. pmc Structural equation modeling highlights the potential of Kim-1 as a biomarker for chronic kidney disease
    Lesley Gardiner
    College of Medicine, Texas A and M Health Science Center, Bryan, TX, USA
    Am J Nephrol 35:152-63. 2012
  5. ncbi request reprint Loss of N-cadherin and alpha-catenin in the proximal tubules of aging male Fischer 344 rats
    Ki Yoon Jung
    Department of Medical Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
    Mech Ageing Dev 125:445-53. 2004
  6. ncbi request reprint Reduction of drug toxicity using dendrimers based on melamine
    Michael F Neerman
    Department of Chemistry, Texas A and M University, College Station, Texas 77843, USA
    Mol Pharm 1:390-3. 2004
  7. ncbi request reprint Ischemia-induced cleavage of cadherins in NRK cells requires MT1-MMP (MMP-14)
    Marisa D Covington
    Department of Medical Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station, Texas, USA
    Am J Physiol Renal Physiol 290:F43-51. 2006
  8. pmc Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line
    Rola Barhoumi
    Department of Veterinary Integrative Biosciences, Texas A and M University, College Station, TX 77843 4458, USA
    Toxicol Appl Pharmacol 253:45-56. 2011
  9. ncbi request reprint Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases
    Marisa D Covington
    Department of Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station, 77843 1114, USA
    Am J Physiol Renal Physiol 289:F280-8. 2005
  10. pmc Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in breast epithelial cell lines
    Rola Barhoumi
    Department of Veterinary Integrative Biosciences, Texas A and M University, College Station, TX 77843 4458, USA
    J Toxicol Sci 34:13-25. 2009

Collaborators

  • Robert C Burghardt
  • Gang Chen
  • Rola Barhoumi
  • Bruce D Hammock
  • George E Davis
  • H Wayne Sampson
  • Jing Jiang
  • Marisa D Covington
  • Lesley Gardiner
  • Hui Ting Chen
  • Michael F Neerman
  • Andy Michael Laughlin
  • Jeffrey M Catania
  • Adebayo D Akintola
  • Dana Dean
  • Eric E Simanek
  • Ki Yoon Jung
  • William H Griffith
  • Sun Ho Han
  • Brian A McCool
  • Adebayo Akintola
  • Jerome Trzeciakowski
  • Joseph V Bonventre
  • Vishal Vaidya
  • David W Forrest
  • Thomas H Welsh
  • Nancy H Ing
  • Dickson D Varner
  • Charles C Love
  • Zachary L Crislip
  • Warren E Zimmer
  • Kayla J Bayless
  • Susan Gaylor
  • David Murchison
  • Sang Soep Nahm

Detail Information

Publications16

  1. pmc Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase
    Alan R Parrish
    Department of Systems Biology and Translational Medicine, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843, USA
    Cell Biol Toxicol 25:217-25. 2009
    ..This is the first report of the use of sEH inhibitors to protect against acute nephrotoxicity and suggests a therapeutic potential of these compounds...
  2. ncbi request reprint Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney
    Adebayo D Akintola
    Department of Systems Biology and Translational Medicine, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Am J Physiol Renal Physiol 294:F170-6. 2008
    ....
  3. ncbi request reprint Ischemia-induced cleavage of cadherins in NRK cells is not sufficient for beta-catenin transcriptional activity
    Gang Chen
    Department of Systems Biology and Translational Medicine, College of Medicine, Texas A and M University System Health Science Center, Texas, USA
    Cell Commun Adhes 14:111-23. 2007
    ..These results suggest that ischemia-induced disruption of cadherin/catenin complexes is not sufficient to stimulate beta-catenin transcriptional activity in NRK cells...
  4. pmc Structural equation modeling highlights the potential of Kim-1 as a biomarker for chronic kidney disease
    Lesley Gardiner
    College of Medicine, Texas A and M Health Science Center, Bryan, TX, USA
    Am J Nephrol 35:152-63. 2012
    ..SEM's ability to investigate complex relationships in an efficient, single model could be utilized to understand the progression of CKD, as well as to develop a predictive model to assess kidney status in the patient...
  5. ncbi request reprint Loss of N-cadherin and alpha-catenin in the proximal tubules of aging male Fischer 344 rats
    Ki Yoon Jung
    Department of Medical Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
    Mech Ageing Dev 125:445-53. 2004
    ..Taken together, these data suggest that aging is associated with decreased expression of N-cadherin and alpha-catenin and is associated with a loss of cell polarity...
  6. ncbi request reprint Reduction of drug toxicity using dendrimers based on melamine
    Michael F Neerman
    Department of Chemistry, Texas A and M University, College Station, Texas 77843, USA
    Mol Pharm 1:390-3. 2004
    ....
  7. ncbi request reprint Ischemia-induced cleavage of cadherins in NRK cells requires MT1-MMP (MMP-14)
    Marisa D Covington
    Department of Medical Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station, Texas, USA
    Am J Physiol Renal Physiol 290:F43-51. 2006
    ..These results demonstrate that ischemia induces increased expression of active MT1-MMP and subsequent disruption of cadherin/catenin complexes, implying that MT1-MMP plays a role in ischemia-induced ARF...
  8. pmc Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line
    Rola Barhoumi
    Department of Veterinary Integrative Biosciences, Texas A and M University, College Station, TX 77843 4458, USA
    Toxicol Appl Pharmacol 253:45-56. 2011
    ..Therefore, the combination of the two-photon acquisition with the unmixing process should provide important insights into the cellular and molecular mechanisms by which BaP and other PAHs alter cellular homeostasis...
  9. ncbi request reprint Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases
    Marisa D Covington
    Department of Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station, 77843 1114, USA
    Am J Physiol Renal Physiol 289:F280-8. 2005
    ..These results demonstrate that ischemia induces a selective metalloproteinase-dependent cleavage of E-cadherin and decrease in N-cadherin that are associated with a disruption of junctional contacts...
  10. pmc Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in breast epithelial cell lines
    Rola Barhoumi
    Department of Veterinary Integrative Biosciences, Texas A and M University, College Station, TX 77843 4458, USA
    J Toxicol Sci 34:13-25. 2009
    ..These results demonstrate the feasibility of analyzing BaP metabolism in situ by multiphoton spectral analysis and also identifying cell-type differences in BaP accumulation and metabolism...
  11. doi request reprint In vitro culture of precision-cut testicular tissue as a novel tool for the study of responses to LH
    Andy Michael Laughlin
    Department of Animal Science, College of Agriculture and Life Sciences, Texas A and M University, College Station, TX 77843, USA
    In Vitro Cell Dev Biol Anim 46:45-53. 2010
    ..These results demonstrate the value of in vitro culture of the precision-cut tissue slices for studies of the regulation of steroidogenesis and gene expression in the stallion testes...
  12. ncbi request reprint Immunohistochemical localization of cadherin and catenin adhesion molecules in the murine growth plate
    H Wayne Sampson
    Department of Systems Biology and Translational Medicine, Texas A and M Health Science Center College of Medicine, 336 Reynolds Building, College Station, TX 77843 1114, USA
    J Histochem Cytochem 55:845-52. 2007
    ..Only alpha-catenin and E-, P-, R-, and VE-cadherin were found in all regions of the growth plate. The results for T-cadherin were inconclusive...
  13. ncbi request reprint Disruption of cadherin/catenin expression, localization, and interactions during HgCl2-induced nephrotoxicity
    Jing Jiang
    Department of Medical Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station 77843 1114, USA
    Toxicol Sci 80:170-82. 2004
    ..Taken together, these data suggest that alterations in cadherin and catenin expression, localization, and interaction are associated with nephrotoxicity...
  14. ncbi request reprint Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery
    Hui Ting Chen
    Department of Chemistry, Texas A and M University, College Station, Texas 77843 3255, USA
    J Am Chem Soc 126:10044-8. 2004
    ..No toxicity--neither mortality nor abnormal blood chemistry based on blood urea nitrogen levels or alanine transaminase activity--was observed in doses up to 2.56 g/kg i.p. and 1.28 g/kg i.v...
  15. ncbi request reprint Cadmium- and mercury-induced intercellular adhesion molecule-1 expression in immortalized proximal tubule cells: evidence for a role of decreased transforming growth factor-beta1
    Jing Jiang
    Department of Medical Pharmacology and Toxicology, Texas A and M University System Health Science Center, College Station, Texas 77843 1114, USA
    Toxicol Appl Pharmacol 179:13-20. 2002
    ..The mechanism of this induction may involve the decreased TGF-beta1 in the conditioned media following metal challenge. Taken together, these studies suggest a link between cytokine and adhesion molecule expression in renal injury...
  16. ncbi request reprint Single-cell RT-PCR detects shifts in mRNA expression profiles of basal forebrain neurons during aging
    Sun Ho Han
    Department of Medical Pharmacology and Toxicology, College of Medicine, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
    Brain Res Mol Brain Res 98:67-80. 2002
    ..These results suggest a shift in the mRNA expression profiles of MS/nDB neuronal populations during aging and exemplify the molecular diversity of cholinergic and GABAergic cells...