Genomes and Genes
I I Ouspenski
Affiliation: Texas Medical Center
- Chromosome condensation factor Brn1p is required for chromatid separation in mitosisI I Ouspenski
Department of Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Mol Biol Cell 11:1305-13. 2000..Overexpression of SMC2, a gene necessary for chromosome condensation, and a homologue of the XCAP-E condensin, does not suppress brn1, pointing to functional specialization of components of the condensin complex...
- A RanBP1 mutation which does not visibly affect nuclear import may reveal additional functions of the ran GTPase systemI I Ouspenski
Department of Cell Biology, Baylor College of Medicine, Houston, Texas, 77030, USA
Exp Cell Res 244:171-83. 1998..These features are shared, in part, by a mutation in RanGEF1, but not in RanGAP1. The yrb1-21 allele suppresses a RanGEF1 mutation, indicating that RanGEF1 and RanBP1 may be involved in the same essential function...
- New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stabilityI I Ouspenski
Department of Cell Biology, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030, USA
Nucleic Acids Res 27:3001-8. 1999..This work shows that analysis of dosage effects is complementary to mutational analysis of chromosome transmission fidelity, as it allows the identification of chromosome stability genes that have not been detected in mutational screens...
- Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeastI I Ouspenski
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030
J Biol Chem 270:1975-8. 1995..Thus RanBP1 is a functional component of a highly conserved molecular system that affects diverse cellular processes. The availability of this gene in S. cerevisiae provides a genetic system for the analysis of RanBP1 function in vivo...
- Specification of kinetochore-forming chromatin by the histone H3 variant CENP-AA A Van Hooser
Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
J Cell Sci 114:3529-42. 2001....
- Molecular cloning of CaYRB1, the Candida albicans RanBP1/YRB1 homologueM Clement
Department of Microbiology and Immunology, Universite de Montreal, C P 6128, Succ Centre Ville, Montreal, Quebec H3C 3J7, Canada
Yeast 18:915-22. 2001..7 kDa. We show that it can complement a S. cerevisiae yrb1 null mutant and that its mRNA does not appear to be regulated in response to conditions inducing morphological changes in C. albicans...