Minako Oshima

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Vaccination with a MHC class II peptide attenuates cellular and humoral responses against tAChR and suppresses clinical EAMG
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 35:183-90. 2002
  2. ncbi request reprint Targeting the antigen-binding site of HLA-restricting alleles in treatment of autoimmune disease
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Crit Rev Immunol 27:271-88. 2007
  3. ncbi request reprint Suppression by mAbs against DQB1 peptides of in vitro proliferation of AChR-specific T cells from myasthenia gravis patients
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 38:161-9. 2005
  4. ncbi request reprint Vaccination with a MHC class II peptide in Alum and inactive pertussis strongly ameliorates clinical MG in C57BL/6 mice
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Neuroimmunol 171:8-16. 2006
  5. ncbi request reprint Subtle differences in HLA DQ haplotype-associated presentation of AChR alpha-chain peptides may suffice to mediate myasthenia gravis
    Philip R Deitiker
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 39:277-88. 2006
  6. doi request reprint T-cell recognition of acetylcholine receptor provides a reliable means for monitoring autoimmunity to acetylcholine receptor in antibody-negative myasthenia gravis patients
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 45:153-60. 2012
  7. doi request reprint Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Neuroimmunol 240:121-8. 2011
  8. ncbi request reprint Use of alum and inactive Bordetella pertussis for generation of antibodies against synthetic peptides in mice
    Takahiro Maruta
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Immunol Invest 35:137-48. 2006
  9. ncbi request reprint Responses in vitro of peripheral blood lymphocytes from patients with myasthenia gravis to stimulation with human acetylcholine receptor alpha-chain peptides: analysis in relation to age, thymic abnormality, and ethnicity
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Immunol 66:32-42. 2005
  10. doi request reprint Association of HLA Class II alleles and haplotypes with cervical dystonia: HLA DR13-DQ6 (DQB1*0604) homozygotes are at greatly increased risk of cervical dystonia in Caucasian Americans
    Philip R Deitiker
    Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 44:167-76. 2011

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Vaccination with a MHC class II peptide attenuates cellular and humoral responses against tAChR and suppresses clinical EAMG
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 35:183-90. 2002
    ..In addition, the Ab responses in the vaccinated group was also lower against tAChR and some of the B-cell epitope-containing tAChR alpha-chain peptides...
  2. ncbi request reprint Targeting the antigen-binding site of HLA-restricting alleles in treatment of autoimmune disease
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Crit Rev Immunol 27:271-88. 2007
    ..The strategy could provide an effective means for immunointervention in other autoimmune and allergic responses...
  3. ncbi request reprint Suppression by mAbs against DQB1 peptides of in vitro proliferation of AChR-specific T cells from myasthenia gravis patients
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 38:161-9. 2005
    ..It may also potentially be adapted for down-regulation of undesirable immune responses such as in other autoimmune diseases, allergic reactions, or clinical conditions where immune responses to a therapeutic protein develop...
  4. ncbi request reprint Vaccination with a MHC class II peptide in Alum and inactive pertussis strongly ameliorates clinical MG in C57BL/6 mice
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    J Neuroimmunol 171:8-16. 2006
    ..It also reduced antibody and T-cell responses against tAChR. The results have important implications for the possible immunotherapy of MG by targeting disease-associated MHC...
  5. ncbi request reprint Subtle differences in HLA DQ haplotype-associated presentation of AChR alpha-chain peptides may suffice to mediate myasthenia gravis
    Philip R Deitiker
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 39:277-88. 2006
    ..Groups of A1*0301:B1*0302, A1*0501:B1*0201 and A1*0102:B1*0604 showed earlier ages of disease onset relative to those of A1*0102:B1*0602 or A1*0505:B1*0301...
  6. doi request reprint T-cell recognition of acetylcholine receptor provides a reliable means for monitoring autoimmunity to acetylcholine receptor in antibody-negative myasthenia gravis patients
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 45:153-60. 2012
    ..The proliferative assay was equally efficient using a mixture of eight peptides frequently recognized by MG T cells. This T-cell proliferative assay should provide a reliable method for monitoring seronegative MG patients...
  7. doi request reprint Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Neuroimmunol 240:121-8. 2011
    ..1/year) were associated with a significantly higher T-cell response to BoNT/A in CD. T cell responses to BoNT/A did not differ between CD patients who had clinically responsive and non-responsive status at the time of enrollment...
  8. ncbi request reprint Use of alum and inactive Bordetella pertussis for generation of antibodies against synthetic peptides in mice
    Takahiro Maruta
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Immunol Invest 35:137-48. 2006
    ..Use of Alum + iBP greatly increased the production of antibodies for most of the peptides. The results have important implications for human vaccine formulation involving peptides...
  9. ncbi request reprint Responses in vitro of peripheral blood lymphocytes from patients with myasthenia gravis to stimulation with human acetylcholine receptor alpha-chain peptides: analysis in relation to age, thymic abnormality, and ethnicity
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Immunol 66:32-42. 2005
    ..015) and alpha 78-93 (p = 0.053), and in recognition of residues alpha 12-27, alpha 56-71, alpha 134-150, and alpha 146-162 (0.0072 < p < 0.064) when two ethnic groups were compared with each other...
  10. doi request reprint Association of HLA Class II alleles and haplotypes with cervical dystonia: HLA DR13-DQ6 (DQB1*0604) homozygotes are at greatly increased risk of cervical dystonia in Caucasian Americans
    Philip R Deitiker
    Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA
    Autoimmunity 44:167-76. 2011
    ..However, longer distance associations within an extended and conserved DQB1*0604 bearing haplotype leave a possibility that a locus proximal to DQB1 might be involved...
  11. doi request reprint Human T-cell responses to botulinum neurotoxin: proliferative responses in vitro of lymphocytes from botulinum neurotoxin A-treated movement disorder patients
    Minako Oshima
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    J Neuroimmunol 237:66-72. 2011
    ..BoNT-treated patients gave significantly higher in vitro T-cell responses to TeNT than did the controls...
  12. doi request reprint Antibody and T cell recognition of the light chain of botulinum neurotoxin A in two high-responder mouse strains
    M Zouhair Atassi
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Immunobiology 217:1-7. 2012
    ..Responses to each T cell or Ab epitope were under separate genetic control. T and B (antibody) cell recognition regions may coincide, but there were also regions recognized only by Abs or by T cells...
  13. ncbi request reprint Myasthenia gravis induced in mice by immunization with the recombinant extracellular domain of rat muscle-specific kinase (MuSK)
    Smita Jha
    Department of Biology and Biochemistry, University of Houston, TX 77204, USA
    J Neuroimmunol 175:107-17. 2006
    ..Myasthenic sera inhibited agrin-induced AChR aggregation in C2C12 myotubes. Conclusion: Anti-MuSK Abs induce MG, which might also result from blocking the agrin-signaling pathway...