Research Topics
Species | T NeliusSummaryAffiliation: Texas Tech University Health Sciences Center Country: USA Publications
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Publications
Oral/metronomic cyclophosphamide-based chemotherapy as option for patients with castration-refractory prostate cancer: review of the literatureT Nelius
Department of Urology, Texas Tech University Health Sciences Center, Lubbock, USA
Cancer Treat Rev 37:444-55. 2011..The intention of this review is to evaluate the efficacy and toxicity of oral/metronomic cyclophosphamide in the treatment of patients with castration-refractory prostate cancer...
PSA surge/flare-up in patients with castration-refractory prostate cancer during the initial phase of chemotherapyT Nelius
Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX 79430 7260, USA
Prostate 69:1802-7. 2009..The cause and the impact of this phenomenon are discussed controversially. The intention of this review is to define the significance of initial PSA surge/flare-up and to increase awareness to this phenomenon in the urological community...
Leiomyosarcoma of the urinary bladder presenting as life threatening gross hematuriaThomas Nelius
Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Suite 260, 3502 9th Street, Lubbock, TX 79415, USA
Med Oncol 27:562-7. 2010..A life threatening episode of gross hematuria guided to the final diagnosis and treatment. Due to the rarity of this malignancy, we present this case including a review of the existing literature relative to the diagnosis and treatment...
Impact of PSA flare-up in patients with hormone-refractory prostate cancer undergoing chemotherapyThomas Nelius
Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Suite 260, 3502 9th Street, Lubbock, TX 79415, USA
Int Urol Nephrol 40:97-104. 2008....
Clinical outcome of patients with docetaxel-resistant hormone-refractory prostate cancer treated with second-line cyclophosphamide-based metronomic chemotherapyThomas Nelius
Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 7260, Lubbock, TX 79430 7260, USA
Med Oncol 27:363-7. 2010..These attributes in combination with immunoregulatory and antiangiogenic potentials make CP also a prime candidate for combination with other treatment regimens...
Characterization of PEDF: a multi-functional serpin family proteinS Filleur
Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, Texas 79430 6591, USA
J Cell Biochem 106:769-75. 2009....
Androgen receptor targets NFkappaB and TSP1 to suppress prostate tumor growth in vivoThomas Nelius
Department of Urology, Texas Tech University Health Sciences Center, Texas Tech University, Lubbock, TX
Int J Cancer 121:999-1008. 2007..Our data indicate that intermittent androgen ablation is preferable to continuous withdrawal, a standard treatment for early-stage prostate cancer. (c) 2007 Wiley-Liss, Inc...
Extraluminal colonic carcinoma invading into kidney: a case report and review of the literatureJ Nelson
Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX 79430 7260, USA
ISRN Urol 2011:707154. 2011..Due to the rarity of this event, we present this case including a review of the existing literature relative to the diagnosis and treatment...
Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancerStephanie Filleur
Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Cancer Res 65:5144-52. 2005..Our results map active regions for the two PEDF functions, signaling via distinct receptors, identify candidate peptides, and provide their mechanism of action for future development of PEDF-based tumor therapies...
A randomized study of docetaxel and dexamethasone with low- or high-dose estramustine for patients with advanced hormone-refractory prostate cancerThomas Nelius
Department of Urology, Otto von Guericke University Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
BJU Int 98:580-5. 2006....
Characterization of prognostic factors and efficacy in a phase-II study with docetaxel and estramustine for advanced hormone refractory prostate cancerThomas Nelius
Department of Urology, Otto von Guericke University Magdeburg, Magdeburg, Germany
Onkologie 28:573-8. 2005..We investigated the combination of docetaxel and estramustine in patients with HRPC regarding efficacy and prognostic parameters...
Alpha1-antitrypsin inhibits angiogenesis and tumor growthHanhua Huang
Department of Urology and Robert H. Lurie Comprehensive Cancer Center, Northwestern University Medical School, Chicago, IL 60611, USA
Int J Cancer 112:1042-8. 2004..Comparative analysis of the human tumors and normal tissues of origin showed correlation between reduced local alpha(1)-antitrypsin expression and more aggressive tumor growth...
