T Nelius

Summary

Affiliation: Texas Tech University Health Sciences Center
Country: USA

Publications

  1. pmc Extraluminal colonic carcinoma invading into kidney: a case report and review of the literature
    J Nelson
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX 79430 7260, USA
    ISRN Urol 2011:707154. 2011
  2. pmc TFE3 Translocation-Associated Renal Cell Carcinoma Presenting as Avascular Necrosis of the Femur in a 19-Year-Old Patient: Case Report and Review of the Literature
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Lubbock, TX 79415, USA
    Case Report Med 2011:432917. 2011
  3. doi request reprint Clinical outcome of patients with docetaxel-resistant hormone-refractory prostate cancer treated with second-line cyclophosphamide-based metronomic chemotherapy
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 7260, Lubbock, TX 79430 7260, USA
    Med Oncol 27:363-7. 2010
  4. ncbi request reprint Oral/metronomic cyclophosphamide-based chemotherapy as option for patients with castration-refractory prostate cancer: review of the literature
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, USA
    Cancer Treat Rev 37:444-55. 2011
  5. doi request reprint PSA surge/flare-up in patients with castration-refractory prostate cancer during the initial phase of chemotherapy
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX 79430 7260, USA
    Prostate 69:1802-7. 2009
  6. ncbi request reprint Impact of PSA flare-up in patients with hormone-refractory prostate cancer undergoing chemotherapy
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Suite 260, 3502 9th Street, Lubbock, TX 79415, USA
    Int Urol Nephrol 40:97-104. 2008
  7. doi request reprint Leiomyosarcoma of the urinary bladder presenting as life threatening gross hematuria
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Suite 260, 3502 9th Street, Lubbock, TX 79415, USA
    Med Oncol 27:562-7. 2010
  8. doi request reprint Characterization of PEDF: a multi-functional serpin family protein
    S Filleur
    Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, Texas 79430 6591, USA
    J Cell Biochem 106:769-75. 2009
  9. ncbi request reprint Pigment epithelium-derived factor expression prolongs survival and enhances the cytotoxicity of low-dose chemotherapy in castration-refractory prostate cancer
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX, USA
    Cell Death Dis 5:e1210. 2014
  10. pmc Androgen receptor targets NFkappaB and TSP1 to suppress prostate tumor growth in vivo
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Texas Tech University, Lubbock, TX
    Int J Cancer 121:999-1008. 2007

Collaborators

  • S Filleur
  • T Kalinski
  • J Nelson
  • A Haynes
  • J Paddack
  • Hanhua Huang
  • K Rinard
  • C Samathanam
  • D E Leocádio
  • Dorina Veliceasa
  • Noel P Bouck
  • Steven C Campbell
  • Olga V Volpert
  • Dhugal F Bedford

Detail Information

Publications16

  1. pmc Extraluminal colonic carcinoma invading into kidney: a case report and review of the literature
    J Nelson
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX 79430 7260, USA
    ISRN Urol 2011:707154. 2011
    ..Due to the rarity of this event, we present this case including a review of the existing literature relative to the diagnosis and treatment...
  2. pmc TFE3 Translocation-Associated Renal Cell Carcinoma Presenting as Avascular Necrosis of the Femur in a 19-Year-Old Patient: Case Report and Review of the Literature
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Lubbock, TX 79415, USA
    Case Report Med 2011:432917. 2011
    ..Due to the rarity of this malignancy, we present this case including a review of the existing literature relative to diagnosis and treatment...
  3. doi request reprint Clinical outcome of patients with docetaxel-resistant hormone-refractory prostate cancer treated with second-line cyclophosphamide-based metronomic chemotherapy
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 7260, Lubbock, TX 79430 7260, USA
    Med Oncol 27:363-7. 2010
    ..These attributes in combination with immunoregulatory and antiangiogenic potentials make CP also a prime candidate for combination with other treatment regimens...
  4. ncbi request reprint Oral/metronomic cyclophosphamide-based chemotherapy as option for patients with castration-refractory prostate cancer: review of the literature
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, USA
    Cancer Treat Rev 37:444-55. 2011
    ..The intention of this review is to evaluate the efficacy and toxicity of oral/metronomic cyclophosphamide in the treatment of patients with castration-refractory prostate cancer...
  5. doi request reprint PSA surge/flare-up in patients with castration-refractory prostate cancer during the initial phase of chemotherapy
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, TX 79430 7260, USA
    Prostate 69:1802-7. 2009
    ..The cause and the impact of this phenomenon are discussed controversially. The intention of this review is to define the significance of initial PSA surge/flare-up and to increase awareness to this phenomenon in the urological community...
  6. ncbi request reprint Impact of PSA flare-up in patients with hormone-refractory prostate cancer undergoing chemotherapy
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Suite 260, 3502 9th Street, Lubbock, TX 79415, USA
    Int Urol Nephrol 40:97-104. 2008
    ....
  7. doi request reprint Leiomyosarcoma of the urinary bladder presenting as life threatening gross hematuria
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Medical Office Plaza, Suite 260, 3502 9th Street, Lubbock, TX 79415, USA
    Med Oncol 27:562-7. 2010
    ..A life threatening episode of gross hematuria guided to the final diagnosis and treatment. Due to the rarity of this malignancy, we present this case including a review of the existing literature relative to the diagnosis and treatment...
  8. doi request reprint Characterization of PEDF: a multi-functional serpin family protein
    S Filleur
    Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, Texas 79430 6591, USA
    J Cell Biochem 106:769-75. 2009
    ....
  9. ncbi request reprint Pigment epithelium-derived factor expression prolongs survival and enhances the cytotoxicity of low-dose chemotherapy in castration-refractory prostate cancer
    T Nelius
    Department of Urology, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX, USA
    Cell Death Dis 5:e1210. 2014
    ..Metastases were reduced in PEDF-DTX-5 mg/kg compared with other treatments, suggesting that PEDF-DTX delayed metastases formation. Our results advocate that PEDF/low-dose chemotherapy may represent a new therapeutic alternative for CRPC...
  10. pmc Androgen receptor targets NFkappaB and TSP1 to suppress prostate tumor growth in vivo
    Thomas Nelius
    Department of Urology, Texas Tech University Health Sciences Center, Texas Tech University, Lubbock, TX
    Int J Cancer 121:999-1008. 2007
    ..Our data indicate that intermittent androgen ablation is preferable to continuous withdrawal, a standard treatment for early-stage prostate cancer. (c) 2007 Wiley-Liss, Inc...
  11. doi request reprint Transitional cell carcinoma due to chronic UroLume stent irritation
    J Paddack
    Department of Urology, Texas Tech University Health Sciences Center, Lubbock, Texas 79415, USA
    Urology 73:995-6. 2009
    ..We report a case of high-grade urothelial carcinoma associated with chronic UroLume application...
  12. doi request reprint [Self-inflicted penile strangulation]
    T Nelius
    Texas Tech University Health Sciences Center, Department of Urology
    Aktuelle Urol 41:64-6. 2010
    ..They can lead to edema, maceration, to local infections up to Fournier gangrene or penile necrosis with or without involvement of the urethra. Injuries by these means are often challenging for the treating urologist...
  13. ncbi request reprint Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer
    Stephanie Filleur
    Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Cancer Res 65:5144-52. 2005
    ..Our results map active regions for the two PEDF functions, signaling via distinct receptors, identify candidate peptides, and provide their mechanism of action for future development of PEDF-based tumor therapies...
  14. ncbi request reprint A randomized study of docetaxel and dexamethasone with low- or high-dose estramustine for patients with advanced hormone-refractory prostate cancer
    Thomas Nelius
    Department of Urology, Otto von Guericke University Magdeburg, Leipziger Str 44, D 39120 Magdeburg, Germany
    BJU Int 98:580-5. 2006
    ....
  15. ncbi request reprint Characterization of prognostic factors and efficacy in a phase-II study with docetaxel and estramustine for advanced hormone refractory prostate cancer
    Thomas Nelius
    Department of Urology, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Onkologie 28:573-8. 2005
    ..We investigated the combination of docetaxel and estramustine in patients with HRPC regarding efficacy and prognostic parameters...
  16. ncbi request reprint Alpha1-antitrypsin inhibits angiogenesis and tumor growth
    Hanhua Huang
    Department of Urology and Robert H Lurie Comprehensive Cancer Center, Northwestern University Medical School, Chicago, IL 60611, USA
    Int J Cancer 112:1042-8. 2004
    ..Comparative analysis of the human tumors and normal tissues of origin showed correlation between reduced local alpha(1)-antitrypsin expression and more aggressive tumor growth...