Frederick A Moore

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. doi request reprint Is there a role for aggressive use of fresh frozen plasma in massive transfusion of civilian trauma patients?
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston, TX, USA
    Am J Surg 196:948-58; discussion 958-60. 2008
  2. doi request reprint Evidence-based medical information technology: the next generation
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston, Texas, USA
    J Trauma 63:1195-205. 2007
  3. doi request reprint Massive transfusion in trauma patients: tissue hemoglobin oxygen saturation predicts poor outcome
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston Texas, USA
    J Trauma 64:1010-23. 2008
  4. doi request reprint Intestinal ischemic preconditioning after ischemia/reperfusion injury in rat intestine: profiling global gene expression patterns
    Stacey D Moore-Olufemi
    Department of Pediatric Surgery, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Dig Dis Sci 55:1866-77. 2010
  5. ncbi request reprint Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion
    Norio Sato
    Department of Surgery, University of Texas Houston, Houston, Texas 77030, USA
    J Trauma 58:455-61; discussion 461. 2005
  6. ncbi request reprint Patients with impending abdominal compartment syndrome do not respond to early volume loading
    Zsolt Balogh
    Department of Surgery, Division of General Surgery, University of Texas at Houston Medical School, Houston, TX 77030, USA
    Am J Surg 186:602-7; discussion 607-8. 2003
  7. doi request reprint Computer protocol facilitates evidence-based care of sepsis in the surgical intensive care unit
    Bruce A McKinley
    Department of Surgery, The Methodist Hospital Research Institute, Houston, Texas, USA
    J Trauma 70:1153-66; discussion 1166-7. 2011
  8. ncbi request reprint Fresh frozen plasma should be given earlier to patients requiring massive transfusion
    Ernest A Gonzalez
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas, USA
    J Trauma 62:112-9. 2007
  9. ncbi request reprint Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome
    Zsolt Balogh
    Department of Surgery, Intensive Care Unit, Memorial Hermann Hospital, University of Texas Houston Medical School, Houston, USA
    Arch Surg 138:637-42; discussion 642-3. 2003
  10. ncbi request reprint Abdominal compartment syndrome: the cause or effect of postinjury multiple organ failure
    Zsolt Balogh
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas 77030, USA
    Shock 20:483-92. 2003

Detail Information

Publications88

  1. doi request reprint Is there a role for aggressive use of fresh frozen plasma in massive transfusion of civilian trauma patients?
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston, TX, USA
    Am J Surg 196:948-58; discussion 958-60. 2008
    ..Damage control resuscitation (DCR) with early plasma in combat casualties requiring massive transfusion (MT) decreases early deaths from bleeding...
  2. doi request reprint Evidence-based medical information technology: the next generation
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston, Texas, USA
    J Trauma 63:1195-205. 2007
  3. doi request reprint Massive transfusion in trauma patients: tissue hemoglobin oxygen saturation predicts poor outcome
    Frederick A Moore
    Department of Surgery, The Methodist Hospital, Houston Texas, USA
    J Trauma 64:1010-23. 2008
    ....
  4. doi request reprint Intestinal ischemic preconditioning after ischemia/reperfusion injury in rat intestine: profiling global gene expression patterns
    Stacey D Moore-Olufemi
    Department of Pediatric Surgery, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Dig Dis Sci 55:1866-77. 2010
    ..In an effort to investigate the molecular mechanisms responsible for the protective effects afforded by IPC, we sought to characterize the global gene expression pattern in rats subjected to IPC in the setting of IR injury...
  5. ncbi request reprint Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion
    Norio Sato
    Department of Surgery, University of Texas Houston, Houston, Texas 77030, USA
    J Trauma 58:455-61; discussion 461. 2005
    ..We now hypothesize that arginine and glutamine differentially modulate the early proinflammatory transcription factors activated by gut I/R...
  6. ncbi request reprint Patients with impending abdominal compartment syndrome do not respond to early volume loading
    Zsolt Balogh
    Department of Surgery, Division of General Surgery, University of Texas at Houston Medical School, Houston, TX 77030, USA
    Am J Surg 186:602-7; discussion 607-8. 2003
    ..We evaluated our prospective resuscitation database to determine how patients who developed ACS differ from non-ACS patients in response to early volume loading...
  7. doi request reprint Computer protocol facilitates evidence-based care of sepsis in the surgical intensive care unit
    Bruce A McKinley
    Department of Surgery, The Methodist Hospital Research Institute, Houston, Texas, USA
    J Trauma 70:1153-66; discussion 1166-7. 2011
    ....
  8. ncbi request reprint Fresh frozen plasma should be given earlier to patients requiring massive transfusion
    Ernest A Gonzalez
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas, USA
    J Trauma 62:112-9. 2007
    ..The hypothesis for this study is that our pre-intensive care unit (ICU) massive transfusion (MT) protocol does not adequately correct coagulopathy, and that early uncorrected coagulopathy is predictive of mortality...
  9. ncbi request reprint Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome
    Zsolt Balogh
    Department of Surgery, Intensive Care Unit, Memorial Hermann Hospital, University of Texas Houston Medical School, Houston, USA
    Arch Surg 138:637-42; discussion 642-3. 2003
    ....
  10. ncbi request reprint Abdominal compartment syndrome: the cause or effect of postinjury multiple organ failure
    Zsolt Balogh
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas 77030, USA
    Shock 20:483-92. 2003
    ..This review summarizes our findings...
  11. doi request reprint The epidemiology of sepsis in general surgery patients
    Laura J Moore
    From the Methodist Hospital Research Institute Weill Cornell Medical College, Houston, Texas 77030, USA
    J Trauma 70:672-80. 2011
    ..Our purpose is to describe its current epidemiology in a general surgery (GS) intensive care unit (ICU) where patients are routinely screened and aggressively treated for sepsis by an established protocol...
  12. ncbi request reprint Effects of primary and secondary intra-abdominal hypertension on mesenteric lymph flow: implications for the abdominal compartment syndrome
    Stacey D Moore-Olufemi
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas 77030, USA
    Shock 23:571-5. 2005
    ..Modest elevations in IAP significantly affect mesenteric QL and the development of gut edema. The principle of early abdominal decompression to reduce mesenteric/IVC venous hypertension and capillary pressure is supported by these data...
  13. ncbi request reprint Conventional dose hypertonic saline provides optimal gut protection and limits remote organ injury after gut ischemia reperfusion
    Ernest A Gonzalez
    Department of Surgery, The University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Trauma 61:66-73; discussion 73-4. 2006
    ..We hypothesized that a dose dependent effect exists related to increasing tonicity and that the optimal gut protective dose would provide better protection against remote organ injury than large volume isotonic crystalloids...
  14. ncbi request reprint Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats
    Rosemary A Kozar
    Department of Surgery, University of Texas Houston School of Medicine, Houston, Texas 77030, USA
    Shock 21:433-7. 2004
    ..The individual components of enteral diets may differentially modulate intestinal barrier function, which could have important implications when administered to critically injured patients...
  15. doi request reprint Performance of a computerized protocol for trauma shock resuscitation
    Joseph F Sucher
    Department of Surgery, The Methodist Hospital, 6550 Fannin Street, Smith Tower 1661A, Houston, TX 77030, USA
    World J Surg 34:216-22. 2010
    ....
  16. ncbi request reprint Peroxisome proliferator-activated receptor gamma mediates protection against cyclooxygenase-2-induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion
    Norio Sato
    Department of Surgery, The University of Texas Medical School, Houston, Texas 77030, USA
    Shock 24:462-9. 2005
    ..Reversal of gut inflammation, injury, and impaired transit by high-dose NS-398 is associated with PPAR activation, suggesting a potential role for PPAR-gamma in shock-induced gut protection...
  17. ncbi request reprint Ischemic preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury
    Stacey D Moore-Olufemi
    Department of Surgery, University of Texas Medical School, Houston, TX 77030, USA
    Shock 23:258-63. 2005
    ..Our results show that IR-induced gut dysfunction can be improved by IPC. Both phases of IPC can potentially be useful in the clinical setting of surgical patient care...
  18. ncbi request reprint Hypertonic saline reverses stiffness in a Sprague-Dawley rat model of acute intestinal edema, leading to improved intestinal function
    Ravi S Radhakrishnan
    Department of Surgery, University of Texas Houston Medical School, Houston, TX, USA
    Crit Care Med 35:538-43. 2007
    ..Furthermore, HS administration will abolish these detrimental effects of edema...
  19. ncbi request reprint Both primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of multiple organ failure
    Zsolt Balogh
    Department of Surgery, Memorial Hermann Hospital, University of Texas at Houston Medical School, 77030, USA
    J Trauma 54:848-59; discussion 859-61. 2003
    ..The purpose of this study was to compare the epidemiology of primary and secondary ACS and develop early prediction models in a high-risk cohort who were treated in a similar fashion...
  20. ncbi request reprint Hypertonic saline resuscitation prevents hydrostatically induced intestinal edema and ileus
    Ravi S Radhakrishnan
    Department of Surgery, University of Texas Houston Medical School, Houston, TX, USA
    Crit Care Med 34:1713-8. 2006
    ..We hypothesized that hypertonic saline (7.5%) would reverse these detrimental effects of acute edema...
  21. ncbi request reprint Tissue oxygen saturation predicts the development of organ dysfunction during traumatic shock resuscitation
    Stephen M Cohn
    Department of Surgery, University of Texas Health Science Center, San Antonio, Texas 78229, USA
    J Trauma 62:44-54; discussion 54-5. 2007
    ..Our purpose was to evaluate how well StO2 predicted outcome in high-risk torso trauma patients presenting in shock...
  22. doi request reprint Identification of cardiac dysfunction in sepsis with B-type natriuretic peptide
    Krista L Turner
    Department of Surgery, The Methodist Hospital, Weill Cornell Medical College, 6550 Fannin St, Smith Tower 1661, Houston, TX 77030, USA
    J Am Coll Surg 213:139-46; discussion 146-7. 2011
    ..More recently, BNP elevation has been demonstrated with septic shock and is predictive of death. How BNP levels relate to cardiac function in sepsis remains to be established...
  23. ncbi request reprint The immune-enhancing enteral agents arginine and glutamine differentially modulate gut barrier function following mesenteric ischemia/reperfusion
    Rosemary A Kozar
    Departments of Surgery, University of Texas Houston, Houston, Texas, USA
    J Trauma 57:1150-6. 2004
    ..While recent data has shown that glutamine is beneficial, arginine may be harmful. We therefore hypothesized that the immune-enhancing agents, glutamine and arginine, differentially modulate gut barrier function...
  24. doi request reprint Human polymerized hemoglobin for the treatment of hemorrhagic shock when blood is unavailable: the USA multicenter trial
    Ernest E Moore
    Department of Surgery, Denver Health Medical Center, University of Colorado, Denver, CO, USA
    J Am Coll Surg 208:1-13. 2009
    ..This multicenter phase III trial was the first US study to assess survival of patients resuscitated with a hemoglobin-based oxygen carrier starting at the scene of injury...
  25. pmc Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care
    Lori F Gentile
    Department of Surgery, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Trauma Acute Care Surg 72:1491-501. 2012
    ..Therapy for PICS will involve innovative interventions for immune system rebalance and nutritional support to regain physical function and well-being...
  26. doi request reprint Computerized clinical decision support for traumatic shock resuscitation
    Rachel J Santora
    The Methodist Hospital Houston Weill Medical College of Cornell University, Houston, Texas, USA
    Curr Opin Crit Care 14:679-84. 2008
    ..To review what we learned through implementation of computerized decision support for ICU resuscitation of major torso trauma patients who arrive in shock...
  27. ncbi request reprint The next generation in shock resuscitation
    Frederick A Moore
    Department of Surgery, University of Texas Houston Medical School, Houston, TX 77030, USA
    Lancet 363:1988-96. 2004
    ....
  28. ncbi request reprint Regional hypothermia reduces mucosal NF-kappaB and PMN priming via gut lymph during canine mesenteric ischemia/reperfusion
    Heitham T Hassoun
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas 77030, USA
    J Surg Res 115:121-6. 2003
    ....
  29. ncbi request reprint Preload optimization using "starling curve" generation during shock resuscitation: can it be done?
    Alan B Marr
    University of Texas Houston Medical School, Houston, Texas 77030, USA
    Shock 21:300-5. 2004
    ....
  30. doi request reprint Early cytokine production risk stratifies trauma patients for multiple organ failure
    Kenneth M Jastrow
    Department of Surgery, University of Texas Medical School at Houston, Houston, TX
    J Am Coll Surg 209:320-31. 2009
    ..In animal models of hemorrhagic shock, early (< 24 hours) changes in cytokine production are an index of the systemic inflammatory response syndrome. However, their predictive value in trauma patients remains to be fully elucidated...
  31. doi request reprint Alpha-melanocyte stimulating hormone in critically injured trauma patients
    S Rob Todd
    Department of Surgery, Weill Medical College of Cornell University, Houston, Texas 77030, USA
    J Trauma 66:465-9. 2009
    ..We hypothesized that alpha-MSH levels would be decreased in critically injured patients and that this would correlate with poor outcome...
  32. pmc The USA Multicenter Prehosptial Hemoglobin-based Oxygen Carrier Resuscitation Trial: scientific rationale, study design, and results
    Ernest E Moore
    Department of Surgery, Denver Health Medical Center, University of Colorado Health Sciences Center, 777 Bannock Street, Denver, CO 80204, USA
    Crit Care Clin 25:325-56, Table of Contents. 2009
    ..The benefit-to-risk ratio of PolyHeme is favorable when blood is needed but is not available or an option...
  33. ncbi request reprint Normal versus supranormal oxygen delivery goals in shock resuscitation: the response is the same
    Bruce A McKinley
    Department of Surgery, University of Texas Houston Medical School, 77030, USA
    J Trauma 53:825-32. 2002
    ..Our hypothesis was that by decreasing the Do I endpoint, less crystalloid would be administered. We compare resuscitation responses to the protocol with goals of Do I > or = 600 versus 500 in two patient cohorts...
  34. doi request reprint Sepsis in general surgery: the 2005-2007 national surgical quality improvement program perspective
    Laura J Moore
    Department of Surgery, The Methodist Hospital, Weill Cornell Medical College, 6550 Fannin Street, Houston, TX 77030, USA
    Arch Surg 145:695-700. 2010
    ..To document the incidence, mortality rate, and risk factors for sepsis and septic shock compared with pulmonary embolism and myocardial infarction in the general-surgery population...
  35. ncbi request reprint Vacuum-assisted wound closure achieves early fascial closure of open abdomens after severe trauma
    James W Suliburk
    Department of Surgery, University of Texas Houston Medical School, 77030, USA
    J Trauma 55:1155-60; discussion 1160-1. 2003
    ..This study reviews the efficacy of vacuum-assisted wound closure (VAWC) to obtain primary fascial closure of open abdomens after severe trauma...
  36. ncbi request reprint Resuscitation-induced intestinal edema decreases the stiffness and residual stress of the intestine
    Ravi S Radhakrishnan
    Department of Surgery, University of Texas, Houston Medical School, 77030, USA
    Shock 24:165-70. 2005
    ..Acute intestinal edema leads to a significant loss in stiffness and residual stress and is a plausible explanation for how acute edema impairs intestinal transit...
  37. ncbi request reprint Resuscitation-induced gut edema and intestinal dysfunction
    Stacey D Moore-Olufemi
    Department of Surgery, University of Texas Houston Medical School, Houston, and The Michael E DeBakey Institute, Texas A and M University, College Station, TX 77030, USA
    J Trauma 58:264-70. 2005
    ..The purpose of this study was to create a model of acute hydrostatic gut edema and to evaluate its effect on gut motility and barrier function...
  38. doi request reprint Central venous pressure versus pulmonary artery catheter-directed shock resuscitation
    Bruce A McKinley
    Department of Surgery, The Methodist Hospital and The Methodist Hospital Research Institute, Houston, Texas 77030, USA
    Shock 32:463-70. 2009
    ..Computerized decision support provides a technique to implement complex protocol care processes and analyze patient response...
  39. ncbi request reprint A multidisciplinary clinical pathway decreases rib fracture-associated infectious morbidity and mortality in high-risk trauma patients
    S Rob Todd
    Department of Surgery, The Methodist Hospital, 6550 Fannin Street, Smith Tower 1661, Houston, TX 77030, USA
    Am J Surg 192:806-11. 2006
    ..The purpose of the current study was to evaluate the effect of this pathway on infectious morbidity and mortality...
  40. pmc Monitoring trauma and intensive care unit resuscitation with tissue hemoglobin oxygen saturation
    Rachel J Santora
    Department of Surgery, The Methodist Hospital, 6550 Fannin Street, SM 1661, Houston, TX 77030, USA
    Crit Care 13:S10. 2009
    ..The purpose of the present review is to review our experience with near-infrared spectroscopy (NIRS) monitoring in shock resuscitation and predicting clinical outcomes...
  41. doi request reprint A multidisciplinary protocol improves electrolyte replacement and its effectiveness
    S Rob Todd
    Department of Surgery, The Methodist Hospital, Weill Cornell Medical College, 6550 Fannin Street, Smith Tower 1661, Houston, TX 77030, USA
    Am J Surg 198:911-5. 2009
    ..We implemented a multidisciplinary electrolyte replacement protocol in a tertiary referral center surgical intensive care unit. The purpose of this study was to evaluate its efficacy...
  42. ncbi request reprint Measurement of intestinal edema using an impedance analyzer circuit
    Ravi S Radhakrishnan
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas 77030, USA
    J Surg Res 138:106-10. 2007
    ..However, there is no simple method to measure intestinal tissue water without biopsy. We sought to develop a tissue impedance analyzer to measure tissue edema, without the need for invasive biopsy...
  43. ncbi request reprint Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis
    Ernest A Gonzalez
    Department of Surgery, The University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Trauma 59:1092-8. 2005
    ..In contrast to I/R cell necrosis, apoptosis provides controlled cell death that minimizes inflammation. We therefore hypothesized that HS resuscitation after mesenteric I/R would induce apoptosis and decrease mucosal injury...
  44. ncbi request reprint The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats
    Rosemary A Kozar
    Department of Surgery, University of Texas Houston School of Medicine, Houston, Texas 77030, USA
    Gastroenterology 123:810-6. 2002
    ..The purpose of this study was to determine how different sodium-coupled solutes modulate gut function after ischemia/reperfusion (I/R) in a rodent model...
  45. ncbi request reprint Superior mesenteric artery occlusion models shock-induced gut ischemia-reperfusion
    Rosemary A Kozar
    Department of Surgery, University of Texas Houston, Houston, TX 77030, USA
    J Surg Res 116:145-50. 2004
    ..The purpose of the current study was to compare SMAO to a standard model of controlled hemorrhage (CH) and uncontrolled hemorrhage (UH)...
  46. doi request reprint Gastric alkalinization after major trauma
    Christine S Cocanour
    Department of Surgery, UC Davis Medical Center, Sacramento, California, USA
    J Trauma 64:681-7. 2008
    ..Therefore, we hypothesized that trauma patients have an alkaline gastric environment that may be because of bile reflux...
  47. ncbi request reprint Hypothermia protects against gut ischemia/reperfusion-induced impaired intestinal transit by inducing heme oxygenase-1
    Bashir O Attuwaybi
    Department of Surgery, Trauma Research Center, University of Texas Houston Medical School, Houston, Texas, USA
    J Surg Res 115:48-55. 2003
    ..HO-1 provides cytoprotection in various models of oxidant stress. We, therefore, tested the hypothesis that IH protects against gut I/R-induced impaired intestinal transit via HO-1 induction...
  48. pmc TNFR1-dependent pulmonary apoptosis during ischemic acute kidney injury
    Laura E White
    Department of Surgery and Research Institute, The Methodist Hospital, Houston, Texas, USA
    Am J Physiol Lung Cell Mol Physiol 303:L449-59. 2012
    ..Kidney-lung crosstalk after ischemic AKI represents a complex pathological process, yet focusing on specific biological pathways may yield potential future therapeutic targets...
  49. ncbi request reprint Goal-oriented shock resuscitation for major torso trauma: what are we learning?
    Bruce A McKinley
    Department of Surgery, University of Texas Health Science Center at Houston, Medical School, Houston, Texas 77030, USA
    Curr Opin Crit Care 9:292-9. 2003
    ....
  50. ncbi request reprint Hypertonic saline prevents inflammation, injury, and impaired intestinal transit after gut ischemia/reperfusion by inducing heme oxygenase 1 enzyme
    Bashir Attuwaybi
    Department of Surgery, University of Texas Houston, Houston, Texas 77030, USA
    J Trauma 56:749-58; discussion 758-9. 2004
    ..We therefore hypothesized that HTS prevents gut inflammation, injury, and impaired transit by inducing HO-1 in a model of gut I/R...
  51. ncbi request reprint Early predictors of prolonged mechanical ventilation in major torso trauma patients who require resuscitation
    Steven C Agle
    Department of Surgery, Eastern Carolina University, Greenville, NC, USA
    Am J Surg 192:822-7. 2006
    ..The study purpose was to identify early predictors of prolonged mechanical ventilation in major torso trauma patients...
  52. ncbi request reprint Ketamine inhibits lipopolysacharide (LPS) induced gastric luminal fluid accumulation
    James W Suliburk
    Department of General Surgery, The University of Texas Medical School at Houston, Houston, Texas 77026, USA
    J Surg Res 127:203-7. 2005
    ..The purpose of this study was to determine if the anti-inflammatory properties of ketamine improve impaired gastric emptying and gastrointestinal transit because of LPS...
  53. ncbi request reprint Poloxamer 188 inhibition of ischemia/reperfusion injury: evidence for a novel anti-adhesive mechanism
    Robert L Hunter
    Department of Pathology, University of Texas Medical School Houston, 6431 Fannin Street, MSB 2 136, Houston, TX 77030, USA
    Ann Clin Lab Sci 40:115-25. 2010
    ..The unique structure of P188 facilitates its rapid, but gentle, binding to any exposed hydrophobic domain, restoring normal non-adhesive surfaces and thereby preventing activation of the entire spectrum of deleterious reactions...
  54. doi request reprint Robotic telepresence: a helpful adjunct that is viewed favorably by critically ill surgical patients
    Joseph F Sucher
    Department of Surgery, The Methodist Hospital, Weill Cornell Medical College, Houston, TX 77030, USA
    Am J Surg 202:843-7. 2011
    ..The purpose of this study was to assess how surgical intensive care unit (SICU) patients and their families would perceive robotic telepresence. We hypothesized that they would view such technology positively...
  55. pmc Therapeutic distant organ effects of regional hypothermia during mesenteric ischemia-reperfusion injury
    Rachel J Santora
    Department of Surgery, The Methodist Hospital and Research Institute, Houston, Tex, USA
    J Vasc Surg 52:1003-14. 2010
    ....
  56. doi request reprint Poloxamer 188 prolongs survival of hypotensive resuscitation and decreases vital tissue injury after full resuscitation
    Rongzhen Zhang
    Department of Pathology, University of Texas Houston Medical School, Houston, Texas, USA
    Shock 32:442-50. 2009
    ..Because P188 prolongs survival, decreases fluid requirements, and reduces tissue damage, it deserves further consideration as an adjunct to hypotensive resuscitation...
  57. ncbi request reprint Secondary abdominal compartment syndrome is an elusive early complication of traumatic shock resuscitation
    Zsolt Balogh
    Department of Surgery, Division of General Surgery, University of Texas at Houston Medical School, 6431 Fannin, Suite 4 264, 77030, USA
    Am J Surg 184:538-43; discussion 543-4. 2002
    ..The purpose of this study was to describe major trauma victims who developed secondary ACS during standardized shock resuscitation...
  58. doi request reprint Computerized clinical decision support: a technology to implement and validate evidence based guidelines
    Joseph F Sucher
    Department of Surgery, The Methodist Hospital, Houston Texas, USA
    J Trauma 64:520-37. 2008
    ..The resulting logical process is readily computerized, and, when properly implemented, provides a stable platform for systematic review and study of the process and interventions...
  59. doi request reprint Just say no to intensive care unit starvation: a nutrition education program for surgery residents
    Shawn Spear
    The Methodist Hospital, Houston, Texas, USA
    Nutr Clin Pract 28:387-91. 2013
    ..The purpose of this pilot study was to assess its effectiveness. We hypothesized that our nutrition education program would improve our residents' knowledge of ICU nutrition...
  60. ncbi request reprint Inflammation and the Host Response to Injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care. III. Guidelines for shock resuscitation
    Frederick A Moore
    Department of Surgery, University of Texas at Houston, 77030, USA
    J Trauma 61:82-9. 2006
  61. doi request reprint Epidemiology of sepsis in surgical patients
    Laura J Moore
    Department of Surgery, The University of Texas Health Science Center, Houston, TX 77030, USA
    Surg Clin North Am 92:1425-43. 2012
    ..The article provides definitions and guidelines for the screening and management of sepsis and septic shock...
  62. doi request reprint Availability of acute care surgeons improves outcomes in patients requiring emergent colon surgery
    Laura J Moore
    Department of Surgery, The University of Texas Health Science Center, Houston, TX 77030, USA
    Am J Surg 202:837-42. 2011
    ..We hypothesized that having acute care surgeons to provide comprehensive perioperative care and rapid source control surgery would improve outcome...
  63. ncbi request reprint Intraischemic hypothermia differentially modulates oxidative stress proteins during mesenteric ischemia/reperfusion
    Heitham T Hassoun
    Department of Surgery, UT Houston Medical School, 77030, USA
    Surgery 132:369-76. 2002
    ..We examined the effects of regional intraischemic hypothermia on mesenteric I/R-induced mucosal injury, NF-kappaB activation, and expression of iNOS and HO-1...
  64. doi request reprint Effects of poloxamer 188 on human PMN cells
    Matthew T Harting
    Department of Pediatric Surgery, University of Texas Medical School, Houston, TX 77030, USA
    Surgery 144:198-203. 2008
    ..We studied human PMN oxidative burst and adhesion molecule expression when exposed to P188...
  65. doi request reprint Computerized clinical decision support improves mortality in intra abdominal surgical sepsis
    Laura Jane Moore
    Weill Cornell Medical College, Surgical Critical Care and Acute Care Surgery, Department of Surgery, Houston, TX, USA
    Am J Surg 200:839-43; discussion 843-4. 2010
    ..The authors therefore created a computerized clinical decision support program to facilitate this process, with the goal of improving abdominal sepsis mortality...
  66. ncbi request reprint Complications of nonoperative management of high-grade blunt hepatic injuries
    Rosemary A Kozar
    Department of Surgery, University of Texas Houston, Houston, TX 77030, USA
    J Trauma 59:1066-71. 2005
    ..The purpose of the present study was therefore to define hepatic-related complications and associated treatment modalities in patients undergoing nonoperative management of high-grade blunt hepatic injuries...
  67. doi request reprint Validation of a screening tool for the early identification of sepsis
    Laura J Moore
    Division of Acute Care Surgery, Department of Surgery, The Methodist Hospital, Houston, Texas 77030, USA
    J Trauma 66:1539-46; discussion 1546-7. 2009
    ..We hypothesized that aggressive screening for sepsis would improve early recognition of sepsis and decrease sepsis-related mortality by insuring early appropriate interventions...
  68. ncbi request reprint The two-event construct of postinjury multiple organ failure
    Ernest E Moore
    Department of Surgery, Denver Health Medical Center and University of Colorado Health Sciences Center, Denver, CO 80204, USA
    Shock 24:71-4. 2005
  69. ncbi request reprint Morbidity from rib fractures increases after age 45
    John B Holcomb
    Department of Surgery, University of Texas Health Sciences Center, Houston, TX, USA
    J Am Coll Surg 196:549-55. 2003
    ....
  70. ncbi request reprint Treatment of aspiration in intensive care unit patients
    Frederick A Moore
    Department of Surgery, University of Texas, Houston Medical School 77030, USA
    JPEN J Parenter Enteral Nutr 26:S69-74; discussion S74. 2002
    ..The primary determinants are the nature of the aspirated material and the host response to it. The purpose of this paper is to present treatment algorithms that should be employed in critically ill patients who experience aspiration...
  71. pmc Distal aortic perfusion and cerebrospinal fluid drainage for thoracoabdominal and descending thoracic aortic repair: ten years of organ protection
    Hazim J Safi
    Department of Cardiothoracic and Vascular Surgery, The University of Texas Health Science Center at Houston Medical School, 6410 Fannin Street, Suite 450, Houston, TX 77030, USA
    Ann Surg 238:372-80; discussion 380-1. 2003
    ..To report the long-term results of our experience using cerebrospinal fluid drainage and distal aortic perfusion in descending thoracic and thoracoabdominal aortic repair...
  72. ncbi request reprint Postinjury enteral tolerance is reliably achieved by a standardized protocol
    Rosemary A Kozar
    Department of Surgery, University of Texas Houston, Houston, Texas, USA
    J Surg Res 104:70-5. 2002
    ....
  73. ncbi request reprint Practice management guidelines for nutritional support of the trauma patient
    David G Jacobs
    Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA
    J Trauma 57:660-78; discussion 679. 2004
  74. ncbi request reprint Specific intraluminal nutrients alter mucosal blood flow during gut ischemia/reperfusion
    Rosemary A Kozar
    Department of Surgery, University of Texas Houston, Health Science Center, 77030, USA
    JPEN J Parenter Enteral Nutr 26:226-9. 2002
    ..The objective of this study was to determine whether these specific nutrients are associated with alterations in mucosal perfusion during gut I/R...
  75. ncbi request reprint Unsafe at any age: a retrospective review of all-terrain vehicle injuries in two level I trauma centers from 1995 to 2003
    Lou M Smith
    Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
    J Trauma 58:783-8. 2005
    ..In 1984, Cogbill published an article regarding three-wheelers. These are no longer manufactured, but the injury and death rate with four-wheeled ATVs is high and disproportionately affects young riders...
  76. ncbi request reprint Standardized trauma resuscitation: female hearts respond better
    Bruce A McKinley
    Department of Surgery, University of Texas Houston Medical School, 6431 Fannin, MSB 4 266, Houston, TX 77030, USA
    Arch Surg 137:578-83; discussion 583-4. 2002
    ..Women respond better to standardized shock resuscitation compared with similarly severely injured men...
  77. ncbi request reprint Risk factors for hepatic morbidity following nonoperative management: multicenter study
    Rosemary A Kozar
    University of Texas, Houston 77030, USA
    Arch Surg 141:451-8; discussion 458-9. 2006
    ..Early risk factors for hepatic-related morbidity in patients undergoing initial nonoperative management of complex blunt hepatic injuries can be accurately identified...
  78. ncbi request reprint Nutrition support in adult trauma patients
    S Rob Todd
    Acute Care Surgery, The Methodist Hospital Houston Weill Medical College of Cornell University, 6550 Fannin Street, Smith Tower 1661, TX 77030, USA
    Nutr Clin Pract 21:421-9. 2006
    ..Evidence-based recommendations for clinical practice are presented when available...
  79. ncbi request reprint Secondary abdominal compartment syndrome: a potential threat for all trauma clinicians
    Zsolt Balogh
    Department of Trauma, Division of Surgery, John Hunter Hospital and University of Newcastle, Locked Bag 1, Hunter Region Mail Centre, Newcastle, NSW, Australia
    Injury 38:272-9. 2007
    ..With a reliable, predictive model and new monitoring techniques, trauma clinicians should be able to identify the high-risk patient and attenuate the impact of this syndrome...
  80. ncbi request reprint The impact of diabetes on outcome in traumatically injured patients: an analysis of the National Trauma Data Bank
    Lillian S Kao
    Department of Surgery, University of Texas Health Science Center at Houston, 5656 Kelley St, Suite 30S 62008, Houston, TX 77026, USA
    Am J Surg 192:710-4. 2006
    ..Studies on stress hyperglycemia in trauma patients have largely ignored diabetes, a potential confounder. The purpose of this study was to assess the relationship between diabetes and outcome in trauma patients...
  81. ncbi request reprint Alpha-melanocyte-stimulating hormone protects against mesenteric ischemia-reperfusion injury
    Heitham T Hassoun
    Department of Surgery, University of Texas Medical School at Houston, Houston, Texas 77030, USA
    Am J Physiol Gastrointest Liver Physiol 282:G1059-68. 2002
    ..We conclude that alpha-MSH significantly limits postischemic injury to the rat small intestine...
  82. ncbi request reprint Acute lower extremity compartment syndrome (ALECS) screening protocol in critically ill trauma patients
    Roman Kosir
    Department of Surgery, General and Teaching Hospital, Maribor, Slovenia
    J Trauma 63:268-75. 2007
    ..Acute lower extremity compartment syndrome (ALECS) is a devastating complication that often presents silently in critically injured patients; therefore, we developed a protocol to screen high-risk patients...
  83. ncbi request reprint North American Summit on Aspiration in the Critically Ill Patient: consensus statement
    Stephen A McClave
    Department of Medicine, University of Louisville School of Medicine, Kentucky 40202, USA
    JPEN J Parenter Enteral Nutr 26:S80-5. 2002
    ..Management strategies for treating aspiration pneumonia are based on degree of diagnostic certainty, time of onset, and host factors...
  84. ncbi request reprint Blunt cardiac injuries that require operative intervention: an unsuspected injury
    Alicia Mangram
    Department of Surgery, University of Texas, Houston Medical School, 77020, USA
    J Trauma 54:286-8. 2003
  85. ncbi request reprint Gut dysfunction and intolerance to enteral nutrition in critically ill patients
    Frederick A Moore
    Department of Surgery, University of Texas Houston Medical School, Houston, Tex, USA
    Nestle Nutr Workshop Ser Clin Perform Programme 8:149-65; discussion 165-70. 2003
  86. ncbi request reprint Intra-abdominal hypertension: not just a surgical critical care curiosity
    Zsolt Balogh
    Crit Care Med 33:447-9. 2005
  87. ncbi request reprint The practice of venous thromboembolism prophylaxis in the major trauma patient
    Avery B Nathens
    Department of Surgery, Univeristy of Toronto, Canada
    J Trauma 62:557-62; discussion 562-3. 2007
    ..As the effect of delays in the initiation of prophylaxis on VTE rates is unknown, we set out to evaluate the relationship between late initiation of prophylaxis and VTE...
  88. doi request reprint Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients
    Aman Russom
    Surgical Services and Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospital for Children, Boston, MA, USA
    Clin Chem 54:891-900. 2008
    ..Here, we report the clinical validation of a novel microfluidic leukocyte nucleic acid isolation technique for gene expression analysis from critically ill, hospitalized patients that can be readily used on small volumes of blood...