Research Topics
Species | David N McMurraySummaryAffiliation: Texas A and M Health Science Center Country: USA Publications
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Publications
Altered cellular infiltration and cytokine levels during early Mycobacterium tuberculosis sigC mutant infection are associated with late-stage disease attenuation and milder immunopathology in miceKhairul Bariah Abdul-Majid
Center for Tuberculosis Research, Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, MD 21231 1001, USA
BMC Microbiol 8:151. 2008..The antigenic properties of these strains may alter the progression of disease due to a reduction in host immune cell recruitment to the lungs resulting in disease attenuation and prolonged host survival...- n-3 Fatty acids uniquely affect anti-microbial resistance and immune cell plasma membrane organizationDavid N McMurray
Department of Microbial and Molecular Pathogenesis, Texas A and M Health Science Center, College Station, TX 77843 1313, USA
Chem Phys Lipids 164:626-35. 2011..We conclude that the outcomes of n-3 PUFA-mediated immune cell alterations may be beneficial (e.g., anti-inflammatory) or detrimental (e.g., loss of microbial immunity) depending upon the cell type interrogated... 
Do new TB vaccines have a place in the Expanded Program on Immunization?David N McMurray
Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
Expert Rev Vaccines 10:1675-7. 2011..This study highlights a potentially important issue, which should be addressed prior to the introduction of new TB vaccines and, perhaps, other vaccines that require the induction of a so-called Type 1 T-cell-mediated immune response...- n-3 polyunsaturated fatty acids suppress the localization and activation of signaling proteins at the immunological synapse in murine CD4+ T cells by affecting lipid raft formationWooki Kim
Faculty of Nutrition, Texas A and M University, College Station, TX 77843, USA
J Immunol 181:6236-43. 2008..These data imply that lipid rafts may be targets for the development of dietary agents for the treatment of autoimmune and chronic inflammatory diseases... - Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in miceWooki Kim
Program in Integrative Nutrition and Complex Diseases, Texas A and M University, College Station, TX 77843, USA
J Nutr 139:1042-8. 2009..05) of Cur or Lim with respect to CD4(+) T-cell proliferation in response to anti-CD3/28 mAb. These results suggest that combination chemotherapy (FO+Cur or Lim) may favorably modulate CD4(+) T-cell-mediated inflammation... 
Altered inflammatory responses following transforming growth factor-beta neutralization in experimental guinea pig tuberculous pleurisyShannon Sedberry Allen
Department of Microbial and Molecular Pathogenesis, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 88:430-6. 2008..While TGF-beta is generally thought of as an immunosuppressive cytokine, the results of this study demonstrate its importance in promoting an inflammatory response, and highlight its bipolar nature...- Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesisJennifer M Monk
Program in Integrative Nutrition and Complex Diseases, Texas A and M University, College Station, Texas 77843 2253, USA
Am J Physiol Gastrointest Liver Physiol 302:G153-67. 2012..Moreover, we provide new evidence that dietary n-3 PUFAs attenuate intestinal inflammation in an intestinal epithelial cell PPARδ-independent manner... - Dietary polyunsaturated fatty acids modulate resistance to Mycobacterium tuberculosis in guinea pigsChristine T McFarland
Department of Microbial and Molecular Pathogenesis, Texas A and M Health Science Center, College Station, TX 77843, USA
J Nutr 138:2123-8. 2008..The loss of antigen-specific T-cell functions in addition to impaired resistance to mycobacterial disease suggests a susceptible phenotype in (n-3) fatty acid-fed guinea pigs... - Differential activation of alveolar and peritoneal macrophages from BCG-vaccinated guinea pigsHyosun Cho
Department of Microbial and Molecular Pathogenesis, College of Medicine, The Texas A and M University System Health Science Center, 463 Reynolds Medical Building, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 88:307-16. 2008..tuberculosis. BCG vaccination results in the differential activation of guinea pig AM and PM to promote a Type 1 cytokine milieu and control intracellular mycobacteria... - Transgenic mice enriched in omega-3 fatty acids are more susceptible to pulmonary tuberculosis: impaired resistance to tuberculosis in fat-1 miceDiana L Bonilla
Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M Health Science Center, Texas A and M University, College Station, Texas, USA
J Infect Dis 201:399-408. 2010..These data suggest that n-3 PUFA-supplemented diets might have a detrimental effect on immunity to M. tuberculosis and raise concerns regarding the safety of omega-3 dietary supplementation in humans... - Incorporation of a dietary omega 3 fatty acid impairs murine macrophage responses to Mycobacterium tuberculosisDiana L Bonilla
Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M Health Science Center, College Station, Texas, United States of America
PLoS ONE 5:e10878. 2010..We hypothesized that incorporation of n-3 PUFA suppresses activation of macrophage antimycobacterial responses and favors bacterial growth, in part, by modulating the IFNgamma-mediated signaling pathway... - Neutralization of tumor necrosis factor alpha suppresses antigen-specific type 1 cytokine responses and reverses the inhibition of mycobacterial survival in cocultures of immune guinea pig T lymphocytes and infected macrophagesHyosun Cho
Department of Microbial and Molecular Pathogenesis, The Texas A and M University System Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843 1114, USA
Infect Immun 73:8437-41. 2005..This suggests the crucial role of TNF-alpha in the activation of a type 1 T-cell response against Mycobacterium tuberculosis infection... - Mycobacterium bovis BCG vaccination modulates TNF-alpha production after pulmonary challenge with virulent Mycobacterium tuberculosis in guinea pigsToshiko Yamamoto
Department of Microbial and Molecular Pathogenesis, The Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 87:155-65. 2007..Thus, BCG vaccination allows guinea pigs to modulate TNF-alpha levels in conjunction with a reduction in bacillary loads in their tissues... - fat-1 transgene expression prevents cell culture-induced loss of membrane n-3 fatty acids in activated CD4+ T-cellsYang Yi Fan
Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843 2253, USA
Prostaglandins Leukot Essent Fatty Acids 79:209-14. 2008..05) number of cell divisions. We conclude that fat-1-containing CD4+ T-cells express a physiologically relevant, n-3 PUFA enriched, membrane fatty acid composition which is resistant to conventional cell culture-induced depletion... - Dietary fish oil inhibits antigen-specific murine Th1 cell development by suppression of clonal expansionPing Zhang
Department of Microbial and Molecular Pathogenesis, Texas A and M University System Health Science Center, College Station, TX, USA
J Nutr 136:2391-8. 2006..05) the number of cell divisions in vivo. These studies suggest that the attenuated inflammatory response which accompanies FO feeding may be explained, at least in part, by suppression of Th1 clonal expansion... - Neutralization of TNFalpha alters inflammation in guinea pig tuberculous pleuritisLan H Ly
Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M Health Science Center, 463 Reynolds Medical Building, College Station, TX, USA
Microbes Infect 11:680-8. 2009..Neutralization of TNFalpha hastened the transition to an anti-inflammatory cytokine response in guinea pig pleural granulomas and exudate cells... - Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact culturesKirti V Sawant
Department of Microbial and Molecular Pathogenesis, The Texas A and M University System Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843 1114, USA
Infect Immun 75:1870-7. 2007..tuberculosis infection during the early period of infection... - Cytokine profiles in primary and secondary pulmonary granulomas of Guinea pigs with tuberculosisLan H Ly
Texas A and M Health Science Center, Microbial and Molecular Pathogenesis, 463 Reynolds Medical Building, College Station, TX 77843, USA
Am J Respir Cell Mol Biol 38:455-62. 2008.... - Microdissection of the cytokine milieu of pulmonary granulomas from tuberculous guinea pigsLan H Ly
Department of Microbial and Molecular Pathogenesis, Texas A and M University System Health Science Center, College Station, TX 77843, USA
Cell Microbiol 9:1127-36. 2007..Moreover, analysis of the individual lung lobes at 6 weeks post infection suggests that heterogeneity exists in the cytokine profile between the lobes of the lung... - Dietary eicosapentaenoic acid modulates CTLA-4 expression in murine CD4+ T-cellsLan H Ly
Department of Nutrition and Food Science, Texas A and M University System Health Science Center, College Station, TX, USA
Prostaglandins Leukot Essent Fatty Acids 74:29-37. 2006..01). Therefore, we conclude that dietary EPA may suppress CD4(+) T-cell activation by enhancing the downregulatory co-receptor CTLA-4, while not altering the levels of CD28... - Vaccination with Bacille-Calmette Guérin promotes mycobacterial control in guinea pig macrophages infected in vivoLan H Ly
Department of Microbial and Molecular Pathogenesis, Texas A and M University System Health Science Center, College Station, Texas 77843, USA
J Infect Dis 198:768-71. 2008..Furthermore, significant increases in interferon-gamma, transforming growth factor-beta, tumor necrosis factor-alpha, and interleukin-12p40 cytokine mRNA were seen in the pleural cells of the BCG-vaccinated guinea pigs... - Bioactive dietary long-chain fatty acids: emerging mechanisms of actionRobert S Chapkin
Faculty of Nutrition, Texas A and M University, College Station, TX, USA
Br J Nutr 100:1152-7. 2008.... - Recombinant guinea pig TNF-alpha enhances antigen-specific type 1 T lymphocyte activation in guinea pig splenocytesHyosun Cho
Department of Medical Microbiology and Immunology, The Texas A and M University System Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 87:87-93. 2007..This suggests that TNF-alpha plays an important role in the regulation of Type 1 T cell-mediated immune responses in the guinea pig... - BCG vaccination of guinea pigs modulates Mycobacterium tuberculosis-induced CCL5 (RANTES) production in vitro and in vivoTroy A Skwor
Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 86:419-29. 2006.... - Recombinant guinea pig tumor necrosis factor alpha stimulates the expression of interleukin-12 and the inhibition of Mycobacterium tuberculosis growth in macrophagesHyosun Cho
Department of Medical Microbiology and Immunology, The Texas A and M University System Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843 1114, USA
Infect Immun 73:1367-76. 2005..tuberculosis... - Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated miceQian Jia
Program in Integrative Nutrition and Complex Diseases, Texas A and M University, College Station, TX, USA
Br J Nutr 106:519-29. 2011..These results suggest that dietary lipids and curcumin interact to regulate mucosal homeostasis and the resolution of chronic inflammation in the colon... - Cloning of guinea pig IL-4: reduced IL-4 mRNA after vaccination or Mycobacterium tuberculosis infectionAmminikutty Jeevan
Department of Microbial and Molecular Pathogenesis, Texas A and M Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843 1114, United States
Tuberculosis (Edinb) 91:47-56. 2011..tuberculosis infection modulates IL-4 mRNA expression in the guinea pig. Cloning of guinea pig IL-4 will allow us to address the role of IL-4 in vaccine-induced resistance to pulmonary TB in a highly relevant animal model... - Th17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 miceJennifer M Monk
Program in Integrative Nutrition and Complex Diseases, Texas A and M University System Health Science Center, Texas A and M University, College Station, TX, USA
J Nutr 142:117-24. 2012.... - Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammationRobert S Chapkin
Department of Nutrition and Food Science, Faculty of Nutrition, Kleberg Biotechnology Center, MS 2253, Texas A and M University, College Station, TX 77843 2253, USA
Prostaglandins Leukot Essent Fatty Acids 81:187-91. 2009..We propose that lipid rafts may be targets for the development of n-3 PUFA-containing dietary bioactive agents to down-modulate inflammatory and immune responses and for the treatment of autoimmune and chronic inflammatory diseases... - n-3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activationTim Y Hou
Department of Biochemistry and Biophysics, Texas A and M University, College Station, Texas, USA
Biochem J 443:27-37. 2012..Collectively, these data demonstrate that n-3 PUFA, such as DHA, alter PtdIns(4,5)P2 in CD4+ T-cells, thereby suppressing the recruitment of WASP to the immunological synapse, and impairing actin remodelling in CD4+ T-cells... - Molecular cloning and expression of the IL-10 gene from guinea pigsVijaya R Dirisala
Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
Gene 498:120-7. 2012..The newly cloned guinea pig IL-10 cDNA and recombinant proteins will serve as valuable resources for immunological studies in the guinea pig model of TB and other diseases... - Guinea pig neutrophil-macrophage interactions during infection with Mycobacterium tuberculosisKirti V Sawant
Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M University System Health Science Center, 463 Reynolds Medical Building, College Station, TX 77843 1114, USA
Microbes Infect 12:828-37. 2010..tuberculosis H37Rv alone. Taken together, these data suggest that neutrophil-macrophage interactions may contribute to host defense against M. tuberculosis infection... - Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancerRobert S Chapkin
Faculty of Nutrition, Center for Environmental and Rural Health, Texas A and M University, College Station, TX 77843, USA
J Nutr 137:200S-204S. 2007..Precisely how the immunomodulatory effects of (n-3) PUFAs influence inflammation-associated colonic tumor development is the subject of an ongoing investigation... - Mycobacterium bovis BCG vaccination augments interleukin-8 mRNA expression and protein production in guinea pig alveolar macrophages infected with Mycobacterium tuberculosisMark J Lyons
Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, College Station, Texas 77843, USA
Infect Immun 70:5471-8. 2002..These observations indicate that prior vaccination may alter very early events in the M. tuberculosis-infected lung... - Ultraviolet radiation reduces resistance to Mycobacterium tuberculosis infection in BCG-vaccinated guinea pigsAmminikutty Jeevan
Department of Microbial and Molecular Pathogenesis, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 89:431-8. 2009..tuberculosis in guinea pigs possibly by altering cytokine responses in a UVR dose-dependent manner... - n-3 polyunsaturated fatty acids--physiological relevance of doseWooki Kim
Program in Integrative Nutrition and Complex Diseases, Texas A and M University, College Station, TX 77843, USA
Prostaglandins Leukot Essent Fatty Acids 82:155-8. 2010.... - The Yin-Yang of TNFalpha in the guinea pig model of tuberculosisLan H Ly
Department of Microbial and Molecular Pathogenesis, Texas A and M System Health Science Center, College Station, Texas, 77843 1114, USA
Indian J Exp Biol 47:432-9. 2009..Furthermore, BCG vaccination modulates TNFalpha responses directly in the pulmonary granulomas to reduce tissue damage. The bipolar nature of TNFalpha should be considered as knowledge of this critical molecule continues to grow... - Evaluating the role of tumor necrosis factor-alpha in experimental pulmonary tuberculosis in the guinea pigTodd M Lasco
Department of Medical Microbiology and Immunology, The Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 85:245-58. 2005..Conversely, abrogating TNF-alpha activity in the context of a hyperinflammatory response in non-vaccinated guinea pigs may, in fact, rescue them from immunopathological consequences of overproducing TNF-alpha... - Hematogenous reseeding of the lung in low-dose, aerosol-infected guinea pigs: unique features of the host-pathogen interface in secondary tuberclesDavid N McMurray
Department of Medical Microbiology and Immunology, Reynolds Medical Building, Texas A and M University System Health Science Center, Room 463, College Station, TX 77843 1114, USA
Tuberculosis (Edinb) 83:131-4. 2003..The guinea pig model provides a unique opportunity to examine both the microbial and host factors which constitute that interface... - Effect of Mycobacterium bovis BCG vaccination on Mycobacterium-specific cellular proliferation and tumor necrosis factor alpha production from distinct guinea pig leukocyte populationsTodd M Lasco
Department of Medical Microbiology and Immunology, The Texas A and M University System Health Science Center, College Station, Texas 77843, USA
Infect Immun 71:7035-42. 2003..These results showed that production of bioactive TNF-alpha from mycobacterium-stimulated guinea pig cell cultures positively correlates with the vaccination status of the host and with the virulence of the mycobacterial strain... - Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitisJennifer M Monk
Program in Integrative Nutrition and Complex Diseases, Texas A and M University, College Station, Texas, USA
PLoS ONE 7:e49739. 2012.... - Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 productionYang-Yi Fan
Molecular and Cell Biology Section, Faculty of Nutrition, Texas A and M University Health Science Center, College Station, TX 77843-2471, USA
J Immunol 173:6151-60. 2004..Similar results were obtained when purified DHA was fed. These data demonstrate for the first time that dietary DHA alters T cell membrane microdomain composition and suppresses the PKCtheta; signaling axis... - Tuberculosis: vaccines in the pipelineLan H Ly
Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
Expert Rev Vaccines 7:635-50. 2008..Some of these new vaccines may eventually be recommended for travelers to TB high-burden countries. This paper summarizes the progress of vaccine candidates in animal models to improve, replace or augment BCG vaccination... - Recombinant guinea pig CCL5 (RANTES) differentially modulates cytokine production in alveolar and peritoneal macrophagesTroy A Skwor
Texas A and M University System Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843 1114, USA
J Leukoc Biol 76:1229-39. 2004.... - n-3 PUFA and membrane microdomains: a new frontier in bioactive lipid researchDavid W L Ma
Molecular and Cell Biology Section, Faculty of Nutrition, Texas A and M University, College Station, TX 77843-2471, USA
J Nutr Biochem 15:700-6. 2004..This review examines the role of n-3 PUFA in modulating the lipid composition and functionality of lipid microdomains and its potential significance to human health... - Effects of dietary n-3 polyunsaturated fatty acids on T-cell membrane composition and functionKirsten C Switzer
Molecular and Cell Biology Section, Faculty of Nutrition, Texas A and M University Health Science Center, College Station, Texas 77843-2471, USA
Lipids 39:1163-70. 2004.... - Effect of neutralizing transforming growth factor beta1 on the immune response against Mycobacterium tuberculosis in guinea pigsShannon Sedberry Allen
Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, College Station, Texas 77843, USA
Infect Immun 72:1358-63. 2004..Thus, TGF-beta1 may be involved in the resolution of this local, mycobacterial antigen-specific inflammatory response... - Effect of Mycobacterium bovis BCG vaccination on interleukin-1 beta and RANTES mRNA expression in guinea pig cells exposed to attenuated and virulent mycobacteriaAmminikutty Jeevan
Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, College Station, Texas 77843 1114, USA
Infect Immun 70:1245-53. 2002..tuberculosis. These initial studies indicate that BCG vaccination has a positive effect on IL-1 beta and RANTES mRNA expression by host cells in a highly relevant animal tuberculosis model... - Coordinate cytokine gene expression in vivo following induction of tuberculous pleurisy in guinea pigsShannon Sedberry Allen
Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, College Station, Texas 77843, USA
Infect Immun 71:4271-7. 2003..Analysis of cytokine expression during tuberculous pleurisy may lead to a better understanding of the self-healing nature of this manifestation of tuberculosis... - Recent progress in the development and testing of vaccines against human tuberculosisDavid N McMurray
Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, Reynolds Medical Building, Room 463, College Station, TX 77843 1114, USA
Int J Parasitol 33:547-54. 2003..This review will summarise the most recent progress made toward the development and preclinical evaluation of novel vaccines for human tuberculosis... - Differential expression of gamma interferon mRNA induced by attenuated and virulent Mycobacterium tuberculosis in guinea pig cells after Mycobacterium bovis BCG vaccinationAmminikutty Jeevan
Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, College Station, Texas 77843, USA
Infect Immun 71:354-64. 2003..The mechanism by which virulent mycobacteria suppress IFN-gamma mRNA accumulation is currently under investigation... - Colon cancer, fatty acids and anti-inflammatory compoundsRobert S Chapkin
Faculty of Nutrition, Texas A and M University System Health Science Center, College Station, Texas 77843, USA
Curr Opin Gastroenterol 23:48-54. 2007..To outline recent findings on the efficacy of n-3 polyunsaturated fatty acids in the prevention/treatment of inflammatory bowel disease and colorectal cancer... - Interleukin (IL)-8 (CXCL8) induces cytokine expression and superoxide formation by guinea pig neutrophils infected with Mycobacterium tuberculosisMark J Lyons
Department of Medical Microbiology and Immunology, Texas A and M University, System Health Science Center, Reynolds Medical Building Room 463, University Drive, College Station, TX 77843-1114, USA
Tuberculosis (Edinb) 84:283-92. 2004..CONCLUSIONS: The presence of IL-8 early in the host response to M. tuberculosis infection may be an important contributor to a successful immune response. How essential a role IL-8 plays remains unknown and merits further study... - Dietary n-3 polyunsaturated fatty acids promote activation-induced cell death in Th1-polarized murine CD4+ T-cellsKirsten C Switzer
Molecular and Cell Biology Section, Faculty of Nutrition, Texas A and M University, College Station, TX, USA
J Lipid Res 45:1482-92. 2004..In conclusion, n-3 PUFAs enhance the polarization and deletion of proinflammatory Th1 cells, possibly as a result of alterations in membrane microdomain fatty acid composition... - (n-3) Polyunsaturated fatty acids promote activation-induced cell death in murine T lymphocytesKirsten C Switzer
Molecular and Cell Biology Section, Faculty of Nutrition, Texas A and M University, College Station, TX, USA
J Nutr 133:496-503. 2003..In conclusion, we have identified a novel mechanism by which (n-3) PUFA modulate T cell-mediated immunity by selective deletion of Th1-like cells while maintaining or enhancing the Th2-mediated humoral immune response... - Upregulation of thymosin beta-10 by Mycobacterium bovis infection of bovine macrophages is associated with apoptosisJosé A Gutiérrez-Pabello
Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, Texas 77843, USA
Infect Immun 70:2121-7. 2002..01) and parental cells (P < 0.001). Our evidence suggests that upregulation of thymosin beta-10 in M. bovis-infected macrophages is linked with increased cell death due to apoptosis... - Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid raftsYang-Yi Fan
Faculty of Nutrition, Center for Environmental and Rural Health, Texas A and M University System, Health Science Center, College Station, TX, USA
J Nutr 133:1913-20. 2003..These data indicate for the first time that dietary (n-3) PUFA differentially modulate T-cell raft and soluble membrane phospholipid and fatty acyl composition...