Steve A Maxwell

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. ncbi request reprint Analysis of phosphorylated isoforms of the p53 tumor suppressor protein in human lung carcinoma cells undergoing apoptosis
    S A Maxwell
    Department of Pathology, Texas A and M Health Science Center, College Station 77843 1114, USA
    Electrophoresis 17:1772-5. 1996
  2. ncbi request reprint Telomerase activity in immortalized endothelial cells undergoing p53-mediated apoptosis
    S A Maxwell
    Department of Pathology and Laboratory Medicine, Texas A and M Health Science Center, College Station, USA
    Biochem Biophys Res Commun 241:642-5. 1997
  3. pmc Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines
    S A Maxwell
    Department of Pathology and Laboratory Medicine, Texas A and M University Health Science Center, College Station, TX 77843 1114, USA
    Proc Natl Acad Sci U S A 97:13009-14. 2000
  4. ncbi request reprint Biological and molecular characterization of an ECV-304-derived cell line resistant to p53-mediated apoptosis
    S A Maxwell
    Department of Pathology and Laboratory Medicine, College of Medicine, Texas A and M University System Health Science Center, College Station 77843 1114, USA
    Apoptosis 5:277-90. 2000
  5. ncbi request reprint Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas
    Steve A Maxwell
    Texas A and M University System Health Science Center, Department of Pathology and Laboratory Medicine, College Station, Texas 77843 1114, USA
    J Biol Chem 278:9784-9. 2003
  6. ncbi request reprint Gene expression profiling of p53-sensitive and -resistant tumor cells using DNA microarray
    S A Maxwell
    Texas A and M University System Health Science Center, Department of Pathology and Laboratory Medicine, College Station, TX 77843 1114, USA
    Apoptosis 9:171-9. 2004
  7. ncbi request reprint The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway
    Armando Rivera
    Department of Pathology and Laboratory Medicine, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
    J Biol Chem 280:29346-54. 2005
  8. pmc Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK)
    Jui M Dave
    From the Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas 77843
    J Biol Chem 288:30720-33. 2013
  9. pmc Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation
    Hyeong Il Kwak
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Angiogenesis 15:287-303. 2012
  10. doi request reprint Akt, 14-3-3ζ, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma
    Steve A Maxwell
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Leuk Lymphoma 52:849-64. 2011

Collaborators

  • Kayla J Bayless
  • Jui M Dave
  • Shih Chi Su
  • Hojin Kang
  • Hyeong Il Kwak
  • Armando Rivera
  • Colette A Abbey
  • E Adriana Mendoza

Detail Information

Publications14

  1. ncbi request reprint Analysis of phosphorylated isoforms of the p53 tumor suppressor protein in human lung carcinoma cells undergoing apoptosis
    S A Maxwell
    Department of Pathology, Texas A and M Health Science Center, College Station 77843 1114, USA
    Electrophoresis 17:1772-5. 1996
    ..The differential expression of isoforms 1, 4, and 7 in apoptotic cells suggests that one or more specific phosphorylation events generating these forms of p53 could play a role in regulating the function of p53 in apoptosis...
  2. ncbi request reprint Telomerase activity in immortalized endothelial cells undergoing p53-mediated apoptosis
    S A Maxwell
    Department of Pathology and Laboratory Medicine, Texas A and M Health Science Center, College Station, USA
    Biochem Biophys Res Commun 241:642-5. 1997
    ..Telomerase activity was measured by a PCR-based telomeric repeat amplification protocol (TRAP). Telomerase activity was found to be unaffected by overexpression of p53 and apoptosis in immortalized endothelial cells...
  3. pmc Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines
    S A Maxwell
    Department of Pathology and Laboratory Medicine, Texas A and M University Health Science Center, College Station, TX 77843 1114, USA
    Proc Natl Acad Sci U S A 97:13009-14. 2000
    ..The results directly implicate proline oxidase and the proline/P5C pathway in p53-induced growth suppression and apoptosis...
  4. ncbi request reprint Biological and molecular characterization of an ECV-304-derived cell line resistant to p53-mediated apoptosis
    S A Maxwell
    Department of Pathology and Laboratory Medicine, College of Medicine, Texas A and M University System Health Science Center, College Station 77843 1114, USA
    Apoptosis 5:277-90. 2000
    ..DECV cells should prove to be a useful tool in future studies to elucidate mechanisms of p53-mediated apoptosis and differentiation...
  5. ncbi request reprint Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas
    Steve A Maxwell
    Texas A and M University System Health Science Center, Department of Pathology and Laboratory Medicine, College Station, Texas 77843 1114, USA
    J Biol Chem 278:9784-9. 2003
    ..The presence of proline oxidase in mitochondria, a primary organelle that regulates apoptosis, places this molecule in a subcellular localization that can directly influence the apoptotic pathway and thus tumorigenesis...
  6. ncbi request reprint Gene expression profiling of p53-sensitive and -resistant tumor cells using DNA microarray
    S A Maxwell
    Texas A and M University System Health Science Center, Department of Pathology and Laboratory Medicine, College Station, TX 77843 1114, USA
    Apoptosis 9:171-9. 2004
    ..Our analysis identifies many new potential targets for p53 that play roles in cell cycle regulation, DNA repair, redox control, cell adhesion, apoptosis, and differentiation...
  7. ncbi request reprint The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway
    Armando Rivera
    Department of Pathology and Laboratory Medicine, Texas A and M University System Health Science Center, College Station, TX 77843 1114, USA
    J Biol Chem 280:29346-54. 2005
    ..The activation of calcineurin-regulated transcription factor pathways by proline oxidase might affect gene expression events important to p53 regulation of cell growth and apoptosis...
  8. pmc Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK)
    Jui M Dave
    From the Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas 77843
    J Biol Chem 288:30720-33. 2013
    ....
  9. pmc Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation
    Hyeong Il Kwak
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Angiogenesis 15:287-303. 2012
    ..These findings help explain why S1P and GF synergize to stimulate robust sprouting in 3D collagen matrices...
  10. doi request reprint Akt, 14-3-3ζ, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma
    Steve A Maxwell
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Leuk Lymphoma 52:849-64. 2011
    ..The data implicate activation of an Akt-14-3-3ζ signaling pathway in promoting a multidrug-resistant phenotype associated with a vimentin-dependent invasive behavior in DLBCL cells...
  11. pmc 14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimen
    Steve A Maxwell
    Department of Molecular and Cellular Medicine, The Texas A and M Health Science Center, College Station, Texas 77840 1114, USA
    J Biol Chem 284:22379-89. 2009
    ..Our study implicates 14-3-3zeta in the pathogenesis of DLBCL and suggests a promising combination strategy with a 14-3-3 inhibitor for the treatment of refractory DLBCL...
  12. doi request reprint Non-Hodgkin's B-cell lymphoma: advances in molecular strategies targeting drug resistance
    Steve A Maxwell
    Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Exp Biol Med (Maywood) 238:971-90. 2013
    ..This review highlights the new insights into the molecular basis of chemorefractory B-cell NHL that are facilitating the rational design of novel strategies to overcome drug resistance. ..
  13. pmc Annexin 2 regulates endothelial morphogenesis by controlling AKT activation and junctional integrity
    Shih Chi Su
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas 77843 1114, USA
    J Biol Chem 285:40624-34. 2010
    ..Collectively, we report that annexin 2 regulates endothelial morphogenesis through an adherens junction-mediated pathway upstream of Akt...
  14. doi request reprint Identification of a p53-response element in the promoter of the proline oxidase gene
    Steve A Maxwell
    Department of Molecular and Cellular Medicine, Room 252, College of Medicine, Texas A and M Health Science Center, College Station, TX 77843 1114, USA
    Biochem Biophys Res Commun 369:308-13. 2008
    ..We concluded from these experiments that a p53-binding site is positioned at -1161 to -1188bp upstream of the POX transcriptional start site...