M M Matzuk


Affiliation: Texas Medical Center
Country: USA


  1. CastaƱeda J, Matzuk M. DEVELOPMENTAL BIOLOGY. Toward a rapid and reversible male pill. Science. 2015;350:385-6 pubmed publisher
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    Matzuk M, Dionne L, Guo Q, Kumar T, Lebovitz R. Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinology. 1998;139:4008-11 pubmed
    ..These studies support an important role of SOD1 in female reproductive function and suggest that SOD2 is not essential for ovarian function. ..
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    Chang H, Huylebroeck D, Verschueren K, Guo Q, Matzuk M, Zwijsen A. Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development. 1999;126:1631-42 pubmed
    ..Despite the expression of Smad5 from gastrulation onwards, and in contrast to knockouts of Smad2 and Smad4, Smad5 only becomes essential later in extraembryonic and embryonic development. ..
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    Matzuk M. Revelations of ovarian follicle biology from gene knockout mice. Mol Cell Endocrinol. 2000;163:61-6 pubmed
    ..Thus, GDF-9 functions as an oocyte-secreted growth and differentiation factor during early and late folliculogenesis and at ovulation to regulate several key somatic cell functions essential for female reproduction. ..
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    Matzuk M, Lamb D. Genetic dissection of mammalian fertility pathways. Nat Cell Biol. 2002;4 Suppl:s41-9 pubmed