Jing Liu

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint A novel mutation in GJA3 (connexin46) for autosomal dominant congenital nuclear pulverulent cataract
    Haisong Jiang
    Health Science Center, Shanghai Institute for Biological Sciences, Chinese Academy of Science and Shanghai Second Medical University, Shanghai, People s Republic of China
    Mol Vis 9:579-83. 2003
  2. ncbi request reprint The DNA sequence, annotation and analysis of human chromosome 3
    Donna M Muzny
    Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 440:1194-8. 2006
  3. pmc Morphoproteomic confirmation of an activated nuclear factor-кBp65 pathway in follicular thyroid carcinoma
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School Houston, Texas, USA
    Int J Clin Exp Pathol 5:216-23. 2012
  4. pmc Immunohistochemical expressions of fatty acid synthase and phosphorylated c-Met in thyroid carcinomas of follicular origin
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School Houston, TX 77030, USA
    Int J Clin Exp Pathol 4:755-64. 2011
  5. doi request reprint Morphoproteomics demonstrates activation of mammalian target of rapamycin pathway in papillary thyroid carcinomas with nuclear translocation of MTOR in aggressive histological variants
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, TX, USA
    Mod Pathol 24:1553-9. 2011
  6. ncbi request reprint Thyroid transcription factor-1 immunocytochemical staining of pleural fluid cytocentrifuge preparations for detection of small cell lung carcinoma
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA
    Acta Cytol 48:635-40. 2004
  7. ncbi request reprint Immunostaining for thyroid transcription factor-1 on fine-needle aspiration specimens of lung tumors: a comparison of direct smears and cell block preparations
    Jing Liu
    Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA
    Cancer 102:109-14. 2004
  8. ncbi request reprint Morphoproteomics demonstrates activation of mTOR pathway in anaplastic thyroid carcinoma: a preliminary observation
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, Texas, USA
    Ann Clin Lab Sci 40:211-7. 2010
  9. pmc Immunohistochemical detection of epithelialmesenchymal transition associated with stemness phenotype in anaplastic thyroid carcinoma
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School Houston, Texas 77030, USA
    Int J Clin Exp Pathol 3:755-62. 2010
  10. pmc The importance of fine needle aspiration in conjunction with radiologic examination in the evaluation of granular cell tumor presenting as a thyroid mass: a case report
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA
    Int J Clin Exp Pathol 4:197-9. 2011

Collaborators

Detail Information

Publications69

  1. ncbi request reprint A novel mutation in GJA3 (connexin46) for autosomal dominant congenital nuclear pulverulent cataract
    Haisong Jiang
    Health Science Center, Shanghai Institute for Biological Sciences, Chinese Academy of Science and Shanghai Second Medical University, Shanghai, People s Republic of China
    Mol Vis 9:579-83. 2003
    ..Here, we described a six-generation Chinese family presenting with morphologically homogeneous "nuclear pulverulent" cataracts...
  2. ncbi request reprint The DNA sequence, annotation and analysis of human chromosome 3
    Donna M Muzny
    Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 440:1194-8. 2006
    ....
  3. pmc Morphoproteomic confirmation of an activated nuclear factor-кBp65 pathway in follicular thyroid carcinoma
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School Houston, Texas, USA
    Int J Clin Exp Pathol 5:216-23. 2012
    ..This observation may provide a molecular basis for the tumor biology and targeted therapies for follicular thyroid carcinoma...
  4. pmc Immunohistochemical expressions of fatty acid synthase and phosphorylated c-Met in thyroid carcinomas of follicular origin
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School Houston, TX 77030, USA
    Int J Clin Exp Pathol 4:755-64. 2011
    ....
  5. doi request reprint Morphoproteomics demonstrates activation of mammalian target of rapamycin pathway in papillary thyroid carcinomas with nuclear translocation of MTOR in aggressive histological variants
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, TX, USA
    Mod Pathol 24:1553-9. 2011
    ..The pattern of expression of p-MTOR in papillary thyroid carcinomas may serve as a diagnostic/prognostic marker and a potential therapeutic target...
  6. ncbi request reprint Thyroid transcription factor-1 immunocytochemical staining of pleural fluid cytocentrifuge preparations for detection of small cell lung carcinoma
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA
    Acta Cytol 48:635-40. 2004
    ..To assess whether thyroid transcription factor-1 (TTF-1) immunostaining of cytocentrifuge slides previously stained by the Papanicolaou technique is feasible and useful in diagnosing small cell lung carcinoma (SCLC) in pleural fluid...
  7. ncbi request reprint Immunostaining for thyroid transcription factor-1 on fine-needle aspiration specimens of lung tumors: a comparison of direct smears and cell block preparations
    Jing Liu
    Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA
    Cancer 102:109-14. 2004
    ....
  8. ncbi request reprint Morphoproteomics demonstrates activation of mTOR pathway in anaplastic thyroid carcinoma: a preliminary observation
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, Texas, USA
    Ann Clin Lab Sci 40:211-7. 2010
    ..These preliminary findings warrant future studies in a large series of patients with ATC to evaluate a possible molecular basis for treating chemoradioresistant ATC...
  9. pmc Immunohistochemical detection of epithelialmesenchymal transition associated with stemness phenotype in anaplastic thyroid carcinoma
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School Houston, Texas 77030, USA
    Int J Clin Exp Pathol 3:755-62. 2010
    ..The results warrant future studies on a large series of cases in order to gain the understanding of the tumor biology and to provide molecular basis for restoring the sensitivities to clinical therapies...
  10. pmc The importance of fine needle aspiration in conjunction with radiologic examination in the evaluation of granular cell tumor presenting as a thyroid mass: a case report
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, Texas 77030, USA
    Int J Clin Exp Pathol 4:197-9. 2011
    ....
  11. ncbi request reprint TTF-1 and p63 for distinguishing pulmonary small-cell carcinoma from poorly differentiated squamous cell carcinoma in previously pap-stained cytologic material
    Neda Kalhor
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, 77030, USA
    Mod Pathol 19:1117-23. 2006
    ..p63 immunostaining, however, must be interpreted in conjunction with cytomorphology to distinguish between poorly differentiated pulmonary squamous cell carcinomas and benign cellular constituents of the lung...
  12. ncbi request reprint Fine needle aspiration biopsy and immunostaining findings in an aggressive inflammatory myofibroblastic tumor of the lung: a case report
    Christina D Hannah
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School 77030, USA
    Acta Cytol 51:239-43. 2007
    ..Here we present FNA biopsy findings in conjunction with immunohistochemical studies in a case of primary and recurrent pulmonary IMT...
  13. ncbi request reprint Distinction of pulmonary small cell carcinoma from poorly differentiated squamous cell carcinoma: an immunohistochemical approach
    Hong Zhang
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, TX 77030, USA
    Mod Pathol 18:111-8. 2005
    ..This panel also facilitates diagnosis of combined small cell and non-small cell carcinomas...
  14. pmc Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution
    Stephen Richards
    Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston Texas 77030, USA
    Genome Res 15:1-18. 2005
    ..Overall, a pattern of repeat-mediated chromosomal rearrangement, and high coadaptation of both male genes and cis-regulatory sequences emerges as important themes of genome divergence between these species of Drosophila...
  15. ncbi request reprint The finished DNA sequence of human chromosome 12
    Steven E Scherer
    Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 440:346-51. 2006
    ..The rate of base substitutions in recent evolutionary history shows an overall slowing in hominids compared with primates and rodents...
  16. pmc RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression
    Jing Liu
    Departments of Pharmacology and Biochemistry, UT Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390 9041, USA, Department of Chemistry and Institute for Life Sciences, University of Southampton, Highfield, Southampton, SO17 1BJ, UK and Alnylam Pharmaceuticals, 300 Third St, Cambridge, MA 02142, USA
    Nucleic Acids Res 41:8788-801. 2013
    ..Several different abasic duplexes achieve potent and selective inhibition, providing a broad platform for subsequent development. These findings introduce abasic substitutions as a tool for tailoring RNA duplexes for gene silencing. ..
  17. ncbi request reprint Use of mailed urine specimens in diagnosing urothelial carcinoma by cytology and DNA image analysis
    Jing Liu
    Department of Pathology and Laboratory Medicine, University of Texas at Houston Medical School, Houston, Texas, USA
    Acta Cytol 49:157-62. 2005
    ..To evaluate the usefulness of urine specimens collected via a mailer system and analyzed by cytology and DNA ploidy for the detection of urothelial carcinoma (UC)...
  18. pmc Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless
    Edwin J Ostrin
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
    Genome Res 16:466-76. 2006
    ..These results suggest that the integrated strategy of computational biology, genomics, and genetics is a powerful approach to identify direct downstream targets for any transcription factor genome-wide...
  19. ncbi request reprint Cloning, characterization and promoter analysis of common carp hairy/Enhancer-of-split-related gene, her6
    Jing Liu
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China
    J Genet 85:171-8. 2006
    ....
  20. ncbi request reprint A draft sequence of the rice genome (Oryza sativa L. ssp. indica)
    Jun Yu
    Beijing Genomics Institute Center of Genomics and Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China
    Science 296:79-92. 2002
    ..4% of predicted rice genes had a homolog in A. thaliana. The large proportion of rice genes with no recognizable homologs is due to a gradient in the GC content of rice coding sequences...
  21. ncbi request reprint Molecular characterization of common carp (Cyprinus carpio) Sonic Hedgehog and discovery of its maternal expression
    Na Wang
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China
    Dev Genes Evol 217:299-305. 2007
    ....
  22. ncbi request reprint Expression and localization of SWAP-70 in human fetomaternal interface and placenta during tubal pregnancy and normal placentation
    Jing Liu
    State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 25 Bei Si Huan Xi Road, Beijing 100080, China
    J Histochem Cytochem 55:701-8. 2007
    ..Our results suggest that SWAP-70 may be involved in regulating migration and invasion of trophoblast cells during the processes of embryonic implantation and placentation in primates...
  23. ncbi request reprint [Expression of Daxx in children with acute leukemia]
    Jing Liu
    Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Zhongguo Dang Dai Er Ke Za Zhi 9:33-6. 2007
    ..To investigate Daxx expression and its clinical significance in children with acute leukemia...
  24. ncbi request reprint Identification and characterization of a biomineralization related gene PFMG1 highly expressed in the mantle of Pinctada fucata
    Hai Luo Liu
    Medical School, Tsinghua University, Beijing 100084, People s Republic of China
    Biochemistry 46:844-51. 2007
    ..fucata and may accelerate research on the mechanism of pearl formation...
  25. ncbi request reprint Diagnostic accuracy of human telomerase reverse transcriptase mRNA in malignant pleural effusions: A preliminary report for in situ hybridization detection
    Jun Shu
    Division of Respiratory Medicine, Department of Geriatrics, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China
    Clin Chim Acta 381:131-5. 2007
    ..We assessed the diagnostic performance of hTERT mRNA in cells from pleural fluid in malignant pleural effusions (PEs)...
  26. pmc Thermus thermophilus bacteriophage phiYS40 genome and proteomic characterization of virions
    Tatyana Naryshkina
    Waksman Institute for Microbiology, Kansas City, MO 64110, USA
    J Mol Biol 364:667-77. 2006
    ..phiYS40 has apparently arisen through multiple acts of recombination between different phage genomes as well as through acquisition of bacterial genes...
  27. pmc sli-3 negatively regulates the LET-23/epidermal growth factor receptor-mediated vulval induction pathway in Caenorhabditis elegans
    Bhagwati P Gupta
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Genetics 174:1315-26. 2006
    ..We provide evidence that sli-3 interacts with the EGF signaling pathway components during vulval induction but not during viability and ovulation processes. Thus, sli-3 helps define specificity of the EGF signaling to induce the vulva...
  28. ncbi request reprint [Background study of HIV-1 drug resistant mutations in treatment-naive patients in liaoning province]
    Xiao Xu Han
    Key Laboratory of AIDS Immunology of Ministry of Health, The First Affiliated Hospital, China Medical University, Shenyang 110001, China
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:632-6. 2006
    ..To collect background information on drug resistance mutations in treatment-naïve HIV-1 infected individuals in Liaoning Province...
  29. ncbi request reprint Association of the neuropilin-2 (NRP2) gene polymorphisms with autism in Chinese Han population
    Suping Wu
    Institute of Mental Health, Peking University, Beijing, China
    Am J Med Genet B Neuropsychiatr Genet 144:492-5. 2007
    ..004 and 0.017, respectively). The polymorphisms in the NRP2 gene are associated with autism, implying that the NRP2 gene may render individuals to be predisposed to autism...
  30. pmc A betaPix Pak2a signaling pathway regulates cerebral vascular stability in zebrafish
    Jing Liu
    Department of Biochemistry and Molecular Biology, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, Canada T2N 4N1
    Proc Natl Acad Sci U S A 104:13990-5. 2007
    ..These data identify an essential in vivo role for betaPix and Pak2a during embryonic development and illuminate a previously unrecognized pathway specifically involved in cerebrovascular stabilization...
  31. pmc Assessing the spatial extent of breast tumor intrinsic optical contrast using ultrasound and diffuse optical spectroscopy
    Ang Li
    University of California, Irvine, Beckman Laser Institute and Medical Clinic, Laser Microbeam and Medical Program, Irvine, California 92612, USA
    J Biomed Opt 13:030504. 2008
    ..Analysis indicates that invasive breast tumors with anatomical dimensions of 1 cm may still be detectable at depths of 30 mm or more (the center of the lesion to the surface of tissue) using DOS in a reflectance geometry...
  32. pmc The C. elegans SYS-1 protein is a bona fide beta-catenin
    Jing Liu
    Department of Biological Structure, University of Washington, Seattle, WA 98195 7420, USA
    Dev Cell 14:751-61. 2008
    ..We conclude that the SYS-1 protein belongs to the beta-catenin family and suggest that additional divergent beta-catenins await discovery...
  33. doi request reprint C-banding analysis of eight species of Kengyilia (Poaceae: Triticeae)
    Jian Zeng
    Triticeae Research Institute, Sichuan Agricultural University, Dujiangyan, Sichuan, China
    J Appl Genet 49:11-21. 2008
    ..batalinii had distinct centromeric bands and no banded chromosomes, while K. hirsuta, K. longiglumis, K. melanthera, K. rigidula and K. thoroldiana had more abundant and diagnostic C-bands with interstitial and terminal bands...
  34. doi request reprint Effect and mechanism of ginsenoside Rg3 on postoperative life span of patients with non-small cell lung cancer
    Ping Lu
    Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
    Chin J Integr Med 14:33-6. 2008
    ..To explore the effect and mechanism of ginsenoside Rg3 (Shenyi Capsule) on the postoperative life span of patients with non-small cell lung cancer (NSCLC)...
  35. ncbi request reprint Clinical utility of vascular endothelial growth factor in diagnosing malignant pleural effusions
    Jun Shu
    Division of Respiratory Medicine, Department of Geriatrics, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
    Acta Oncol 46:1004-11. 2007
    ..These findings suggest that VEGF could be used in diagnosing malignant PE as a useful adjunct of conventional algorithm. Different VEGF test strategies, including test on PF, serum and both, may be selected according to practical needs...
  36. ncbi request reprint Antigen-binding characteristics of AbCD71 and its inhibitory effect on PHA-induced lymphoproliferation
    Ping Lei
    Department of Immunology and Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Acta Pharmacol Sin 28:1659-64. 2007
    ....
  37. ncbi request reprint Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism
    Siyi Hu
    Lab of Cellular and Molecular Immunology, School of Life Sciences, University of Science and Technology of China, Hefei 230027, People s Republic of China
    Proteins 70:938-49. 2008
    ..It suggested that the A21 epitope may be another valuable target for designing new anti-ErbB2 therapeutics...
  38. ncbi request reprint Functional characterization of the promoter of human kinetochore protein HEC1: novel link between regulation of the cell cycle protein and CREB family transcription factors
    Liansheng Cheng
    Anhui Province Key Laboratory of Molecular Medicine, School of Life Science, University of Science and Technology of China, Hefei, Anhui, 230027, China
    Biochim Biophys Acta 1769:593-602. 2007
    ..Our study provided a new insight into a potential mechanism of how transcription factors of CREB family are involved in the regulation of kinetochore protein HEC1 in cancer-related cells...
  39. ncbi request reprint Feasibility study on using an infrared thermometer for evaluation and administration of cryosurgery
    Jing Fu Yan
    Cryogenics Lab, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, PR China
    Minim Invasive Ther Allied Technol 16:173-80. 2007
    ..This study may help push forward a novel, low-cost and non-contact way for an efficient performance of cryosurgery...
  40. ncbi request reprint [Impact of multi-layer spiral CT angiography of bronchial artery and pulmonary artery in assessment of the main blood supply to the primary lung cancer]
    Xiang sheng Xiao
    Department of Radiological Diagnosis, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
    Zhonghua Zhong Liu Za Zhi 28:302-5. 2006
    ..To investigate the blood supply of primary lung cancer (PLC) using CT angiography for bronchial artery (BA) and pulmonary artery (PA)...
  41. ncbi request reprint Testosterone is required for delayed cardioprotection and enhanced heat shock protein 70 expression induced by preconditioning
    Jing Liu
    Department of Physiology, Faculty of Medicine, The University of Hong Kong, 4 F Laboratory Block, Faculty of Medicine Buildings, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China
    Endocrinology 147:4569-77. 2006
    ..In conclusion, preconditioning requires testosterone to increase heat shock protein 70 synthesis, which mediates delayed cardioprotection in the male. These effects of testosterone are mediated by the androgen receptor...
  42. ncbi request reprint Expression of SWAP-70 in the uterus and feto-maternal interface during embryonic implantation and pregnancy in the rhesus monkey (Macaca mulatta)
    Jing Liu
    State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 25 Bei Si Huan Xi Road, Beijing 100080, China
    Histochem Cell Biol 126:695-704. 2006
    ..The data indicate that SWAP-70 may be involved in regulating motility of trophoblast cells during embryonic implantation and placentation...
  43. ncbi request reprint A candidate DNA vaccine elicits HCV specific humoral and cellular immune responses
    Li Xin Zhu
    State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Yue Yang Road 320, Shanghai 200031, China
    World J Gastroenterol 10:2488-92. 2004
    ....
  44. ncbi request reprint [CD25 monoclonal antibody for GVHD prophylaxis in non-T-cell depleted haploidentical bone marrow transplantation for treatment of childhood leukemia]
    Hui Ren Chen
    Department of Hematology, The General Hospital of PLA Air Force, Beijing 100036, China
    Zhonghua Er Ke Za Zhi 42:294-8. 2004
    ..The purpose of this study was to explore the effects of CD25 monoclonal antibody on reducing the incidence of severe acute GVHD in haploidentical bone marrow transplantation for the treatment of childhood leukemia...
  45. ncbi request reprint A new recombinant single chain trispecific antibody recruits T lymphocytes to kill CEA (carcinoma embryonic antigen) positive tumor cells in vitro efficiently
    Xiang Bin Wang
    The Institute of Genetics and Developmental Biology, Chinese Academy of Science, 100101, Beijing, China
    J Biochem 135:555-65. 2004
    ....
  46. ncbi request reprint Association between the FOXP2 gene and autistic disorder in Chinese population
    Xiaohong Gong
    Institute of Mental Health, Peking University, Beijing, China
    Am J Med Genet B Neuropsychiatr Genet 127:113-6. 2004
    ..Our findings suggest that the FOXP2 gene may be involved in the pathogenesis of autism in Chinese population...
  47. ncbi request reprint [Clinical study of a new protocol for acute graft-versus host disease prophylaxis in HLA-haploidentical bone marrow transplantation (BMT)]
    Shu Quan Ji
    Department of Hematology, The General Hospital of Air Force PLA, Beijing 100036, China
    Zhonghua Xue Ye Xue Za Zhi 24:416-9. 2003
    ..To explore the feasibility of a new protocol for acute graft versus host disease (aGVHD) prophylaxis in haploidentical bone marrow transplantation...
  48. ncbi request reprint Humanized anti-CD25 monoclonal antibody for prophylaxis of graft-vs-host disease (GVHD) in haploidentical bone marrow transplantation without ex vivo T-cell depletion
    Hui Ren Chen
    Research Institution Of Air Force Hematology PLA, Beijing, China
    Exp Hematol 31:1019-25. 2003
    ..To investigate the effects of a novel anti-IL-2 receptor (CD25) monoclonal antibody, basiliximab, on graft-vs-host disease (GVHD) and engraftment in haploidentical bone marrow transplantation (BMT)...
  49. ncbi request reprint [An efficient approach to the synthesis of a high-quality random peptide repertoire]
    Chang Cheng Yin
    Institute of Genetics and Developmental Biology, The Chinese Academy of Sciences, Beijing 100101, China
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35:921-4. 2003
    ....
  50. pmc Three monophyletic superfamilies account for the majority of the known glycosyltransferases
    Jing Liu
    Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110, USA
    Protein Sci 12:1418-31. 2003
    ....
  51. ncbi request reprint Construction, expression and characterization of the engineered antibody against tumor surface antigen, p185(c-erbB-2)
    Lian Sheng Cheng
    School of Life Science, University of Science and Technology of China, Hefei 230027, China
    Cell Res 13:35-48. 2003
    ..These anti-p185 engineered antibodies have promised to be further modified as a tumor targeting drugs, with a view of application in the diagnosis and treatment of human breast cancer...
  52. ncbi request reprint [A clinical study of haploidentical and G-CSF primed bone marrow transplantation by using CD25 for aGVHD prophylaxis]
    Shu Quan Ji
    Department of Hematology, The General Hospital of Air Force PLA, Beijing, 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:447-51. 2002
    ..The major histocompatibility barrier in the haploidentical related allo-BMT could be crossed by donors primed with G-CSF and GVHD prophylaxis with CD25 antibody in the hosts...
  53. ncbi request reprint A method for constructing reshaping single-domain antibody
    Ju Long Cheng
    Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    Yi Chuan Xue Bao 29:189-95. 2002
    ..coli BL21 (DE3). The antigen-binding affinity of refolded proteins was still in a high level measured by ELISA. These results suggested that this method was feasible and efficient for constructing reshaping Single-domain antibodies...
  54. ncbi request reprint Family-based association study between autism and glutamate receptor 6 gene in Chinese Han trios
    Mei Shuang
    Institute of Mental Health, Peking University, Beijing, China
    Am J Med Genet B Neuropsychiatr Genet 131:48-50. 2004
    ..032). The global chi(2) test for haplotype transmission also revealed an association between GluR6 and autism (chi(2) = 10.78, df = 3, P = 0.013). Our results suggested that GluR6 is in linkage disequilibrium with autism...
  55. ncbi request reprint A gene family of cathepsin L-like proteases of filarial nematodes are associated with larval molting and cuticle and eggshell remodeling
    David B Guiliano
    Department of Biological Sciences, Imperial College of Science and Technology, London SW7 2AY, UK
    Mol Biochem Parasitol 136:227-42. 2004
    ....
  56. ncbi request reprint Two kinds of ENU-induced scant hair mice and mapping of the mutant genes
    Bao jin Wu
    Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, China
    J Dermatol Sci 36:149-56. 2004
    ..To establish mouse models for human diseases through N-ethyl-N-nitrosourea (ENU) mutagenesis, and to provide groundwork to clone genes and study their functions after mapping the mutant genes...
  57. pmc Novel genes encoding six kinds of three-finger toxins in Ophiophagus hannah (king cobra) and function characterization of two recombinant long-chain neurotoxins
    Jing Li
    School of Life Science, University of Science and Technology of China, Hefei 230026, Anhui Province, People s Republic of China
    Biochem J 398:233-42. 2006
    ..This, to our knowledge, is the first observation that recombinant long chain alpha-neurotoxins have a CTX-like cytolytic activity...
  58. ncbi request reprint Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population
    Suping Wu
    Institute of Mental Health, Peking University, Beijing, China
    Biol Psychiatry 58:74-7. 2005
    ..Animal models and linkage data from genome screens indicate that the oxytocin receptor gene (OXTR) is an excellent candidate for research concerning psychiatric disorders, particularly those involving social impairments, such as autism...
  59. ncbi request reprint Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter
    Da ming Gao
    State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, S212, Yueyang Road 320, Shanghai 200031, China
    FEBS Lett 580:1702-8. 2006
    ..The generation of the new transcript is conserved in rats. The identification of novel mlrh-1 variant and promoter is critical for elucidating LRH-1 functions in development and adult tissues...
  60. ncbi request reprint Protein repertoire of double-stranded DNA bacteriophages
    Jing Liu
    Stowers Institute for Medical Research, 1000 E 50th St, Kansas City, MO 64110, USA
    Virus Res 117:68-80. 2006
    ..The information on orthologous genes is essential for evolutionary classification of known bacteriophages and for reconstruction of ancestral phage genomes...
  61. ncbi request reprint Codon optimization, expression, and characterization of an internalizing anti-ErbB2 single-chain antibody in Pichia pastoris
    Siyi Hu
    Laboratory of Molecular and Cellular Immunology, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, PR China
    Protein Expr Purif 47:249-57. 2006
    ..Functional studies showed that the A21 scFv could be internalized with high efficiency after binding to the ErbB2-overexpressing cells, suggesting this regent may prove especially useful for ErbB2-targeted immunotherapy...
  62. ncbi request reprint A new format of single chain tri-specific antibody with diminished molecular size efficiently induces ovarian tumor cell killing
    Jing Liu
    Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Datun Road, 100101, Beijing, China
    Biotechnol Lett 27:1821-7. 2005
    ..This new format of scTsAb possesses properties that support its potential as a new tumor immunotherapeutic agent...
  63. ncbi request reprint [The characteristics of anti-B-cell malignance cytotoxic T lymphocytic clones induced by lymphoma relative peptides]
    Xiao ling Guo
    Department of Hematology, Peking University First Hospital, Beijing 100034, China
    Zhonghua Yi Xue Za Zhi 85:1476-80. 2005
    ..To analyze if the cytotoxic T-cell (CTLs) are peptide-special and HLA restrict, and what is the sequence characteristic of TCRbeta genes...
  64. pmc Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus
    Vinciane Gaussin
    Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 S Orange Ave, MSB Room G 609, Newark, NJ 07103, USA
    Circ Res 97:219-26. 2005
    ..In conclusion, our mouse model demonstrated critical roles for Alk3 signaling in the AV myocardium during the development of AV valves and the annulus fibrosus...
  65. ncbi request reprint Purification and characterization of a single-chain chimeric anti-p185 antibody expressed by CHO-GS system
    Jing Wang
    School of Life Science, University of Science and Technology of China, Hefei, Anhui 230027, China
    Protein Expr Purif 41:68-76. 2005
    ..These results further augment the potential of this recombinant antibody to be a drug candidate for cancer therapy...
  66. pmc The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages
    Tony Kwan
    Targanta Therapeutics, 7170 Frederick Banting, Second Floor, Ville Saint Laurent, QC, Canada H4S 2A1
    Proc Natl Acad Sci U S A 102:5174-9. 2005
    ..These phage genomes offer an exciting opportunity to discern molecular mechanisms of phage evolution and diversity...
  67. ncbi request reprint Predictors of motor development in children prenatally exposed to cocaine
    Cynthia Miller-Loncar
    Brown Medical School, Women and Infants Hospital, Providence, RI 02903, United States
    Neurotoxicol Teratol 27:213-20. 2005
    ..Heavy cocaine use related to poorer motor performance as compared to no use, but there were no effects of level of cocaine use on change in motor skills...
  68. ncbi request reprint Gene identification and expression analysis of 86,136 Expressed Sequence Tags (EST) from the rice genome
    Yan Zhou
    Hangzhou Genomics Institute Institute of Bioinformatics of Zhejiang University Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China
    Genomics Proteomics Bioinformatics 1:26-42. 2003
    ..We also identified some possible library specific genes and a number of enzymes and transcription factors that contribute to rice development...
  69. ncbi request reprint Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract
    Lei Bu
    Shanghai Research Center of Biotechnology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200233, People s Republic of China
    Nat Genet 31:276-8. 2002
    ..We also discovered an association between a missense mutation and Marner cataract in an extensive Danish family. We suggest that HSF4 is critical to lens development...