Yi Ping Li

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Cytokine responses in primary chicken embryo intestinal cells infected with Campylobacter jejuni strains of human and chicken origin and the expression of bacterial virulence-associated genes
    Yi Ping Li
    Department of Poultry, Fish and Fur Animals, National Veterinary Institute VET, Technical University of Denmark DTU, Hangøvej 2, DK 8200 Aarhus N, Denmark
    BMC Microbiol 8:107. 2008
  2. pmc TIMP3: a physiological regulator of adult myogenesis
    Huijie Liu
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, TX 77030, USA
    J Cell Sci 123:2914-21. 2010
  3. ncbi request reprint TNF-alpha is a mitogen in skeletal muscle
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Suite 520B, Houston, TX 77030, USA
    Am J Physiol Cell Physiol 285:C370-6. 2003
  4. pmc TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    FASEB J 19:362-70. 2005
  5. pmc Role of TNF-{alpha} signaling in regeneration of cardiotoxin-injured muscle
    Shuen Ei Chen
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza 520B, Houston, TX 77030, USA
    Am J Physiol Cell Physiol 289:C1179-87. 2005
  6. pmc Src mediates the mechanical activation of myogenesis by activating TNFα-converting enzyme
    Airu Niu
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, TX 77030, USA
    J Cell Sci 126:4349-57. 2013
  7. pmc TACE release of TNF-alpha mediates mechanotransduction-induced activation of p38 MAPK and myogenesis
    Mei Zhan
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza 520B, Houston, TX 77030, USA
    J Cell Sci 120:692-701. 2007
  8. ncbi request reprint Fatiguing exercise reduces DNA binding activity of NF-kappaB in skeletal muscle nuclei
    William J Durham
    Pulmonary and Critical Care Medicine Section, Baylor College of Medicine, Houston, Texas 77030, USA
    J Appl Physiol (1985) 97:1740-5. 2004
  9. ncbi request reprint TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Suite 520B, Houston, Texas 77030, USA
    FASEB J 17:1048-57. 2003
  10. ncbi request reprint Hydrogen peroxide stimulates ubiquitin-conjugating activity and expression of genes for specific E2 and E3 proteins in skeletal muscle myotubes
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Physiol Cell Physiol 285:C806-12. 2003

Research Grants

  1. Mechanisms of Muscle Wasting
    Yi Ping Li; Fiscal Year: 2007

Collaborators

Detail Information

Publications27

  1. pmc Cytokine responses in primary chicken embryo intestinal cells infected with Campylobacter jejuni strains of human and chicken origin and the expression of bacterial virulence-associated genes
    Yi Ping Li
    Department of Poultry, Fish and Fur Animals, National Veterinary Institute VET, Technical University of Denmark DTU, Hangøvej 2, DK 8200 Aarhus N, Denmark
    BMC Microbiol 8:107. 2008
    ..jejuni strains of human and chicken origins and the production of pro-inflammatory cytokines as well as the expression of the bacterial virulence-associated genes during co-cultivation...
  2. pmc TIMP3: a physiological regulator of adult myogenesis
    Huijie Liu
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, TX 77030, USA
    J Cell Sci 123:2914-21. 2010
    ..In addition, downregulation of TIMP3 is mediated by the myogenesis-promoting microRNA miR-206. Thus, TIMP3 is a physiological regulator of myogenic differentiation...
  3. ncbi request reprint TNF-alpha is a mitogen in skeletal muscle
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Suite 520B, Houston, TX 77030, USA
    Am J Physiol Cell Physiol 285:C370-6. 2003
    ..Our data suggest that TNF-alpha activates satellite cells to enter the cell cycle and accelerates G1-to-S phase transition, and these actions may involve activation of early response genes via SRF...
  4. pmc TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    FASEB J 19:362-70. 2005
    ..These data suggest that TNF-alpha acts via p38 to increase atrogin1/MAFbx gene expression in skeletal muscle...
  5. pmc Role of TNF-{alpha} signaling in regeneration of cardiotoxin-injured muscle
    Shuen Ei Chen
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza 520B, Houston, TX 77030, USA
    Am J Physiol Cell Physiol 289:C1179-87. 2005
    ..Functional studies demonstrated an attenuated recovery of contractile force in injured p55(-/-)p75(-/-) soleus. These data suggest that TNF-alpha signaling plays a critical regulatory role in muscle regeneration...
  6. pmc Src mediates the mechanical activation of myogenesis by activating TNFα-converting enzyme
    Airu Niu
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, TX 77030, USA
    J Cell Sci 126:4349-57. 2013
    ..Further, overloading-induced myogenesis and regeneration are impaired in the soleus of Src(+/-) mice. Therefore, Src mediates mechano-activation of TACE and myogenesis...
  7. pmc TACE release of TNF-alpha mediates mechanotransduction-induced activation of p38 MAPK and myogenesis
    Mei Zhan
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza 520B, Houston, TX 77030, USA
    J Cell Sci 120:692-701. 2007
    ..These results indicate that posttranscriptional activation of TACE mediates the mechanotransduction that activates p38-dependent myogenesis via the release of TNF-alpha...
  8. ncbi request reprint Fatiguing exercise reduces DNA binding activity of NF-kappaB in skeletal muscle nuclei
    William J Durham
    Pulmonary and Critical Care Medicine Section, Baylor College of Medicine, Houston, Texas 77030, USA
    J Appl Physiol (1985) 97:1740-5. 2004
    ..These data provide no support for our original hypothesis. Instead, acute fatiguing exercise appears to decrease NF-kappaB activity in muscle under a variety of conditions...
  9. ncbi request reprint TNF-alpha increases ubiquitin-conjugating activity in skeletal muscle by up-regulating UbcH2/E220k
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Suite 520B, Houston, Texas 77030, USA
    FASEB J 17:1048-57. 2003
    ..Thus, UbcH2 up-regulation is a novel response to TNF-alpha/NF-kappaB signaling in skeletal muscle that appears to be essential for the increased ubiquitin conjugation induced by this cytokine...
  10. ncbi request reprint Hydrogen peroxide stimulates ubiquitin-conjugating activity and expression of genes for specific E2 and E3 proteins in skeletal muscle myotubes
    Yi Ping Li
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Physiol Cell Physiol 285:C806-12. 2003
    ..These results suggest that ROS stimulate protein catabolism in skeletal muscle by upregulating the ubiquitin conjugation system...
  11. pmc C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting
    Guohua Zhang
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, TX 77030, USA
    EMBO J 30:4323-35. 2011
    ..Therefore, activation of the p38β MAPK-C/EBPβ signalling pathway appears a key component of the pathogenesis of LLC tumour-induced cachexia...
  12. pmc TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK
    Shuen Ei Chen
    Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Physiol Cell Physiol 292:C1660-71. 2007
    ..These results indicate that TNF-alpha regulates myogenesis and muscle regeneration as a key activator of p38...
  13. pmc Beta3-integrin mediates satellite cell differentiation in regenerating mouse muscle
    Huijie Liu
    Department of Integrative Biology and Pharmacology, University of Texas Health, Science Center, Houston, TX 77030, USA
    FASEB J 25:1914-21. 2011
    ..Thus, β3-integrin is a mediator of satellite cell differentiation in regenerating muscle...
  14. pmc Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2
    Guohua Zhang
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, TX 77030, USA
    FASEB J 27:2893-901. 2013
    ..These results suggest that UBR2 up-regulation in cachectic muscle is mediated by the p38β-C/EBPβ signaling pathway responsible for the bulk of tumor-induced muscle proteolysis...
  15. pmc Curcumin prevents lipopolysaccharide-induced atrogin-1/MAFbx upregulation and muscle mass loss
    Bingwen Jin
    Department of Medicine, Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    J Cell Biochem 100:960-9. 2007
    ..These results indicate that curcumin is effective in blocking LPS-induced loss of muscle mass through the inhibition of p38-mediated upregulation of atrogin-1/MAFbx...
  16. ncbi request reprint Atrophic remodeling of the heart in vivo simultaneously activates pathways of protein synthesis and degradation
    Peter Razeghi
    Division of Cardiology, University of Texas Houston Medical School, Houston, Tex 77030, USA
    Circulation 108:2536-41. 2003
    ..The hypothesis is that mechanical unloading of the mammalian heart has differential effects on pathways of protein synthesis and degradation...
  17. ncbi request reprint Progressive nuclear factor-kappaB activation resistant to inhibition by contraction and curcumin in mdx mice
    William J Durham
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Muscle Nerve 34:298-303. 2006
    ....
  18. pmc Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways
    Alexander Doyle
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, TX 77030, USA
    FASEB J 25:99-110. 2011
    ..Furthermore, TLR4 knockout or p38 MAPK inhibition abolishes LPS-induced muscle proteolysis. Thus, TLR4 mediates LPS-induced muscle catabolism via coordinate activation of the ubiquitin-proteasome and the autophagy-lysosomal pathways...
  19. pmc p38β MAPK upregulates atrogin1/MAFbx by specific phosphorylation of C/EBPβ
    Guohua Zhang
    Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX, 77030, USA
    Skelet Muscle 2:20. 2012
    ..abstract:..
  20. pmc Activation of the ubiquitin-proteasome pathway in the diaphragm in chronic obstructive pulmonary disease
    Coen A C Ottenheijm
    Department of Pulmonary Diseases, 454, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, The Netherlands
    Am J Respir Crit Care Med 174:997-1002. 2006
    ..In the present study we hypothesized that the loss of contractile protein content is associated with activation of the ubiquitin-proteasome pathway in the diaphragm of patients with mild to moderate COPD...
  21. doi request reprint Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2
    Jae Ku Oem
    Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E3, Canada
    J Gen Virol 89:1225-30. 2008
    ..Taken together, our results suggest that HCV NS2 can upregulate the transcription of SREBP-1c and FAS, and thus is probably a contributing factor for HCV-associated steatosis...
  22. pmc RGS10-null mutation impairs osteoclast differentiation resulting from the loss of [Ca2+]i oscillation regulation
    Shuying Yang
    Department of Cytokine Biology, The Forsyth Institute, Boston, Massachusetts 02115, USA
    Genes Dev 21:1803-16. 2007
    ..RGS10 provides a potential therapeutic target for the treatment of bone diseases...
  23. ncbi request reprint Haploinsuffciency for Znf9 in Znf9+/- mice is associated with multiorgan abnormalities resembling myotonic dystrophy
    Wei Chen
    Department of Cytokine Biology, The Forsyth Institute, Boston, MA 02115, USA
    J Mol Biol 368:8-17. 2007
    ..Znf9 transgenic mice raised Znf9 and Clc1 expression and rescued the myotonic dystrophy phenotype in Znf9+/- mice. Our results suggest that the Znf9 haploinsufficiency contributes to the myotonic dystrophy phenotype in Znf9+/- mice...
  24. ncbi request reprint Human osteopetroses and the osteoclast V-H+-ATPase enzyme system
    Kalu U E Ogbureke
    Department of Oral Biology, Maxillofacial Pathology School of Dentistry, Medical College of Georgia, Augusta, Georgia 30912, USA
    Front Biosci 10:2940-54. 2005
    ....
  25. pmc Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescence
    Wei Chen
    Department of Cytokine Biology, The Forsyth Institute and Harvard School of Dental Medicine, 140 The Fenway, Boston, MA 02115, USA
    Hum Mol Genet 16:410-23. 2007
    ..The finding of this novel cathepsin K function provides insight into the pathomechanism of pycnodysostosis and may provide new drug targets for diseases involved in OC-related abnormal bone homeostasis...
  26. ncbi request reprint [Molecular cloning and expression analysis of a novel human gene ZNF18]
    Li Li Guo
    Biomedical Research Institute, College of Life Sciences, Beijing Normal University, Beijing 100875, China
    Yi Chuan 27:523-30. 2005
    ..0, especially in the embryo heart at E10.5. These expression results suggest that ZNF18 may play an important role in the development of embryo heart...
  27. ncbi request reprint Molecular cloning, developmental expression, promoter analysis and functional characterization of the mouse CNBP gene
    Ken Shimizu
    Department of Cytokine Biology, The Forsyth Institute, Boston, MA 02115, USA
    Gene 307:51-62. 2003
    ..Our finds suggest that CNBP may play an important role in cell proliferation and tissue patterning during anterior-posterior axis, craniofacial and limb development by targeting c-Myc...

Research Grants2

  1. Mechanisms of Muscle Wasting
    Yi Ping Li; Fiscal Year: 2007
    ..The achievement of these three aims will facilitate our long-term goal: to develop effective therapeutic strategies in the treatment of myriad patients with cachexic muscle wasting. ..