Yi Li

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
    Yi Li
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:15853-8. 2003
  2. pmc Alzheimer's disease markers, hypertension, and gray matter damage in normal elderly
    Lidia Glodzik
    Center of Excellence on Aging, Center for Brain Health, Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 33:1215-27. 2012
  3. pmc Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents
    Lisa Mosconi
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 34:22-34. 2013
  4. pmc Maternal age affects brain metabolism in adult children of mothers affected by Alzheimer's disease
    Lisa Mosconi
    New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 33:624.e1-9. 2012
  5. pmc Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice
    Shixia Huang
    Program in Cancer Biology and Genetics, Sloan Kettering Institute, New York, NY 10021, USA
    Genome Biol 6:R84. 2005
  6. pmc Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders
    Lidia Glodzik
    Department of Psychiatry, New York University School of Medicine, Center of Excellence on Aging, Center for Brain Health, 145 East 32nd Street, 5th Floor, New York, NY 10016, USA
    Neurobiol Aging 32:2131-41. 2011
  7. pmc Structural brain changes in normal individuals with a maternal history of Alzheimer's
    Valentina Berti
    Center for Brain Health, New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 32:2325.e17-26. 2011
  8. pmc mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma
    Xiaoyi Hu
    Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Neoplasia 7:356-68. 2005
  9. pmc Surgery and brain atrophy in cognitively normal elderly subjects and subjects diagnosed with mild cognitive impairment
    Richard P Kline
    Department of Anesthesiology, New York University Langone Medical Center, New York, New York 10016, USA
    Anesthesiology 116:603-12. 2012
  10. pmc Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype
    Katrina Podsypanina
    Program in Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    BMC Med 2:24. 2004

Collaborators

Detail Information

Publications16

  1. pmc Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
    Yi Li
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:15853-8. 2003
    ..Thus, the developmental heterogeneity of different breast cancers is in part a consequence of differential effects of oncogenes on distinct cell types in the breast...
  2. pmc Alzheimer's disease markers, hypertension, and gray matter damage in normal elderly
    Lidia Glodzik
    Center of Excellence on Aging, Center for Brain Health, Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 33:1215-27. 2012
    ..In this presymptomatic stage when no cognitive impairment is present, AD biomarkers and HTN have additive effects on gray matter damage...
  3. pmc Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents
    Lisa Mosconi
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 34:22-34. 2013
    ..NH and ≥ 71% for MH vs. PH, with relative risk = 1.9-5.1 (p values < 0.005). NL individuals with AD-affected mothers show co-occurring Aβ increases and hypometabolism in AD-vulnerable regions, suggesting an increased risk for AD...
  4. pmc Maternal age affects brain metabolism in adult children of mothers affected by Alzheimer's disease
    Lisa Mosconi
    New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 33:624.e1-9. 2012
    ..There were no associations between paternal age and metabolism in any group. Evidence for a maternally inherited, maternal age-related mechanism provides further insight on risk factors and genetic transmission in late-onset AD...
  5. pmc Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice
    Shixia Huang
    Program in Cancer Biology and Genetics, Sloan Kettering Institute, New York, NY 10021, USA
    Genome Biol 6:R84. 2005
    ..These mice might therefore be useful models for discovering changes in gene expression during cancer development...
  6. pmc Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders
    Lidia Glodzik
    Department of Psychiatry, New York University School of Medicine, Center of Excellence on Aging, Center for Brain Health, 145 East 32nd Street, 5th Floor, New York, NY 10016, USA
    Neurobiol Aging 32:2131-41. 2011
    ....
  7. pmc Structural brain changes in normal individuals with a maternal history of Alzheimer's
    Valentina Berti
    Center for Brain Health, New York University School of Medicine, New York, NY 10016, USA
    Neurobiol Aging 32:2325.e17-26. 2011
    ..Our findings support the use of regional brain atrophy as a preclinical biomarker for LOAD among at-risk individuals...
  8. pmc mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma
    Xiaoyi Hu
    Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Neoplasia 7:356-68. 2005
    ....
  9. pmc Surgery and brain atrophy in cognitively normal elderly subjects and subjects diagnosed with mild cognitive impairment
    Richard P Kline
    Department of Anesthesiology, New York University Langone Medical Center, New York, New York 10016, USA
    Anesthesiology 116:603-12. 2012
    ..Using magnetic resonance imaging data from the Alzheimer's Disease Neuroimaging Initiative, we tested the hypothesis that surgery would impact brain parameters associated with progression of dementia...
  10. pmc Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype
    Katrina Podsypanina
    Program in Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    BMC Med 2:24. 2004
    ..Secondary events also appear to be required for mammary tumorigenesis in MMTV-Neu transgenic mice because the transgene in the tumors usually contains an acquired mutation that activates the Neu protein-tyrosine kinase...
  11. pmc Novel detection of pancreatic and duodenal homeobox 1 autoantibodies (PAA) in human sera using luciferase immunoprecipitation systems (LIPS) assay
    William Donelan
    Department of Pathology, Immunology and Laboratory Medicine, Gainesville, Florida 32610, USA
    Int J Clin Exp Pathol 6:1202-10. 2013
    ..In conclusion, we have developed a liquid-phase, non-radioactive, sensitive and specific LIPS assay to detect PAA in human sera, providing a useful tool for evaluating the clinical relevance of PAA...
  12. pmc Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia
    Lidia Glodzik
    Center for Brain Health, Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
    J Cereb Blood Flow Metab 31:671-9. 2011
    ..6, P=0.05). An elevated risk for vascular pathology is associated with a reduced response to hypercapnia in both hippocampal and cortical tissue. The VR(h) is more sensitive to vascular burden than either resting CBF or brain volume...
  13. pmc Induction of ovarian cancer by defined multiple genetic changes in a mouse model system
    Sandra Orsulic
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Cancer Cell 1:53-62. 2002
    ..The induced ovarian tumors in mice resembled human ovarian carcinomas in their rapid progression and intraperitoneal metastatic spread...
  14. pmc Pancreatic duodenal homeobox 1 protein is a novel beta-cell-specific autoantigen for type I diabetes
    Shi Wu Li
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0275, USA
    Lab Invest 90:31-9. 2010
    ..The presence of PAAs in prediabetic NOD mice and human T1D patients, and Pdx1-specific T-cell proliferation in NOD mice provide a strong rationale for further investigation of the pathogenic role of immune responses against Pdx1 in T1D...
  15. pmc Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases
    Yang Yu
    Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA
    J Neurochem 108:1480-94. 2009
    ..These studies provide new insight into the developmental regulation of site-specific tau phosphorylation and identify the likely sites required for the abnormal hyperphosphorylation of tau in AD...
  16. pmc Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's
    Lisa Mosconi
    New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 107:5949-54. 2010
    ..Present findings may motivate further research on familial transmission and parent-of-origin effects in LOAD...