H Lacorazza

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells
    H Daniel Lacorazza
    Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Cancer Cell 9:175-87. 2006
  2. ncbi The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells
    H Daniel Lacorazza
    Laboratory of Molecular Aspects of Hematopoiesis, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Immunity 17:437-49. 2002
  3. ncbi The emerging role of the myeloid Elf-1 like transcription factor in hematopoiesis
    H Daniel Lacorazza
    Laboratory of Molecular Aspects of Hematopoiesis, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Blood Cells Mol Dis 31:342-50. 2003
  4. ncbi Exclusion and inclusion of TCR alpha proteins during T cell development in TCR-transgenic and normal mice
    H Daniel Lacorazza
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Immunol 173:5591-600. 2004

Collaborators

Detail Information

Publications4

  1. ncbi The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells
    H Daniel Lacorazza
    Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Cancer Cell 9:175-87. 2006
    ..Thus, MEF plays an important role in the decision of stem/primitive progenitor cells to divide or remain quiescent by regulating their entry to the cell cycle...
  2. ncbi The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells
    H Daniel Lacorazza
    Laboratory of Molecular Aspects of Hematopoiesis, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Immunity 17:437-49. 2002
    ..Our results uncover a specific role of MEF in the development and function of NK cells and in innate immunity...
  3. ncbi The emerging role of the myeloid Elf-1 like transcription factor in hematopoiesis
    H Daniel Lacorazza
    Laboratory of Molecular Aspects of Hematopoiesis, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Blood Cells Mol Dis 31:342-50. 2003
    ..MEF interacts with other TFs such as AML1 (Runx1) and with the cyclin A/cdk2 kinase complex. In this review, we discuss the biology of MEF in the context of the other members of this family of transcriptional regulators...
  4. ncbi Exclusion and inclusion of TCR alpha proteins during T cell development in TCR-transgenic and normal mice
    H Daniel Lacorazza
    Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Immunol 173:5591-600. 2004
    ..In searching for the mechanism(s) governing this selective TCRalpha down-regulation, we present evidence for the role of protein tyrosine kinase signaling and coreceptor involvement. This mechanism may be operating in normal thymocytes...

Research Grants5

  1. Regulation of Innate Immunity and Hematopoiesis by MEF
    H Lacorazza; Fiscal Year: 2007
    ..abstract_text> ..
  2. Transcriptional Regulation of Development and Maintenance of Memory T Lymphocytes
    H Lacorazza; Fiscal Year: 2009
    ..This project will also aid to understand survival of functional memory T cells in the site of primary infection to enhance recall responses. ..
  3. Transcriptional Regulation of Development and Maintenance of Memory T Lymphocytes
    H Daniel Lacorazza; Fiscal Year: 2010
    ..This project will also aid to understand survival of functional memory T cells in the site of primary infection to enhance recall responses. ..
  4. Transcriptional Regulation of Development and Maintenance of Memory T Lymphocytes
    H Daniel Lacorazza; Fiscal Year: 2010
    ..This project will also aid to understand survival of functional memory T cells in the site of primary infection to enhance recall responses. ..