M Økland

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. ncbi request reprint The Neurospora circadian clock regulates a transcription factor that controls rhythmic expression of the output eas(ccg-2) gene
    D Bell-Pedersen
    Department of Biology, Texas A and M University, College Station, TX 77843, USA
    Mol Microbiol 41:897-909. 2001
  2. pmc The Neurospora circadian clock: simple or complex?
    D Bell-Pedersen
    Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
    Philos Trans R Soc Lond B Biol Sci 356:1697-709. 2001
  3. pmc Circadian rhythms from multiple oscillators: lessons from diverse organisms
    Deborah Bell-Pedersen
    Center for Research on Biological Clocks, Department of Biology, Texas A and M University, College Station, Texas 77843 3258, USA
    Nat Rev Genet 6:544-56. 2005
  4. ncbi request reprint Two circadian timing circuits in Neurospora crassa cells share components and regulate distinct rhythmic processes
    Renato M de Paula
    Department of Biology, Center for Research on Biological Clocks, Texas A and M University, College Station, TX 77843, USA
    J Biol Rhythms 21:159-68. 2006
  5. pmc A connection between MAPK pathways and circadian clocks
    Renato M de Paula
    Center for Biological Clocks Research, Program for the Biology of Filamentous Fungi, and Department of Biology, Texas A and M University, Texas 77843, USA
    Cell Cycle 7:2630-4. 2008
  6. pmc Circadian rhythmicity mediated by temporal regulation of the activity of p38 MAPK
    Michael W Vitalini
    Center for Biological Clocks Research, Faculty of Genetics, and Program for the Biology of Filamentous Fungi, 3258 TAMU Department of Biology, Texas A and M University, College Station, TX 77843, USA
    Proc Natl Acad Sci U S A 104:18223-8. 2007
  7. ncbi request reprint The rhythms of life: circadian output pathways in Neurospora
    Michael W Vitalini
    Center for Biological Clocks Research, Department of Biology, Texas A and M University, College Station, TX 77843, USA
    J Biol Rhythms 21:432-44. 2006
  8. pmc Circadian rhythms in Neurospora crassa and other filamentous fungi
    Yi Liu
    Department of Physiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9040, USA
    Eukaryot Cell 5:1184-93. 2006
  9. ncbi request reprint The Neurospora crassa pheromone precursor genes are regulated by the mating type locus and the circadian clock
    Piotr Bobrowicz
    Department of Plant Pathology and Microbiology, Texas A and M University, College Station 77843, USA
    Mol Microbiol 45:795-804. 2002
  10. pmc Assignment of an essential role for the Neurospora frequency gene in circadian entrainment to temperature cycles
    Antonio M Pregueiro
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Proc Natl Acad Sci U S A 102:2210-5. 2005

Research Grants

  1. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 1999
  2. Molecular Genetic Analysis of Fungal Circadian Rythms
    Deborah Bell Pedersen; Fiscal Year: 2009
  3. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2007
  4. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2006
  5. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2005
  6. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2004
  7. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2003
  8. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2002
  9. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2001
  10. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2000

Collaborators

  • D Bell-Pedersen
  • Paul E Hardin
  • P L Lakin-Thomas
  • Vincent M Cassone
  • J J Loros
  • David Earnest
  • S S Golden
  • J Dunlap
  • James E Galagan
  • Ulrich Schulte
  • ERIC SELKER
  • Stephan Seiler
  • Yi Liu
  • Deborah Bell Pedersen
  • Michael W Vitalini
  • Renato M de Paula
  • Alejandro Correa
  • Andrew V Greene
  • Louis W Morgan
  • Katherine A Borkovich
  • Zachary A Lewis
  • Daniel J Ebbole
  • Lindsay Bennett
  • Antonio M Pregueiro
  • Richard H Gomer
  • Xin Xie
  • Irene J March
  • Michael J Bailey
  • Mari L Shinohara
  • Piotr Bobrowicz
  • Teresa M Lamb
  • Charles S Goldsmith
  • Carol A Jones
  • William D Park
  • Kyung Suk Seo
  • Christian Heintzen
  • Nathan Price-Lloyd
  • Michael Freitag
  • Lisa A Alex
  • Ian Paulsen
  • David Catcheside
  • Nora Plesofsky
  • Marta Goodrich-Tanrikulu
  • Nick D Read
  • Michael Plamann
  • Matthew S Sachs
  • Rebecca O'Rourke
  • George A Marzluf
  • Hirokazu Inoue
  • Rowland Davis
  • Chizu Ishii
  • Frederick Bowring
  • Robert Pratt
  • Eric R Kalkman
  • Heather H Wilkinson
  • Keiichiro Suzuki
  • Gloria E Turner
  • Jane Yeadon
  • Claude Selitrennikoff
  • John Paietta
  • Gertrud Mannhaupt
  • Alex Zelter
  • Oded Yarden
  • Wataru Sakai
  • Frank E Nargang
  • Alan Radford
  • Rodolfo Aramayo
  • Michael Polymenis
  • Hubertus Haas
  • Nancy Keller
  • Terry L Thomas
  • Phillip D Beremand
  • Rick Hammer
  • Rebecca Pawlak

Detail Information

Publications20

  1. ncbi request reprint The Neurospora circadian clock regulates a transcription factor that controls rhythmic expression of the output eas(ccg-2) gene
    D Bell-Pedersen
    Department of Biology, Texas A and M University, College Station, TX 77843, USA
    Mol Microbiol 41:897-909. 2001
    ..These data suggest that the Neurospora crassa circadian clock regulates an unknown transcription factor, which in turn activates the expression of eas(ccg-2) at specific times of the day...
  2. pmc The Neurospora circadian clock: simple or complex?
    D Bell-Pedersen
    Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
    Philos Trans R Soc Lond B Biol Sci 356:1697-709. 2001
    ..Thus even a relatively simple lower eukaryote can be used to address questions about a complex, networked circadian system...
  3. pmc Circadian rhythms from multiple oscillators: lessons from diverse organisms
    Deborah Bell-Pedersen
    Center for Research on Biological Clocks, Department of Biology, Texas A and M University, College Station, Texas 77843 3258, USA
    Nat Rev Genet 6:544-56. 2005
    ..In both cases, the temporal coordination of a multi-oscillator system is essential for producing robust circadian rhythms of gene expression and biological activity...
  4. ncbi request reprint Two circadian timing circuits in Neurospora crassa cells share components and regulate distinct rhythmic processes
    Renato M de Paula
    Department of Biology, Center for Research on Biological Clocks, Texas A and M University, College Station, TX 77843, USA
    J Biol Rhythms 21:159-68. 2006
    ..The results are consistent with the presence of 2 circadian oscillators within Neurospora cells, which the authors speculate may interact with each other through the shared WC proteins...
  5. pmc A connection between MAPK pathways and circadian clocks
    Renato M de Paula
    Center for Biological Clocks Research, Program for the Biology of Filamentous Fungi, and Department of Biology, Texas A and M University, Texas 77843, USA
    Cell Cycle 7:2630-4. 2008
    ..Thus, the role of the clock in regulation of the activity of MAPK pathways provides important clues into the function of the circadian clock as a tumor suppressor...
  6. pmc Circadian rhythmicity mediated by temporal regulation of the activity of p38 MAPK
    Michael W Vitalini
    Center for Biological Clocks Research, Faculty of Genetics, and Program for the Biology of Filamentous Fungi, 3258 TAMU Department of Biology, Texas A and M University, College Station, TX 77843, USA
    Proc Natl Acad Sci U S A 104:18223-8. 2007
    ..crassa circadian clock allows anticipation and preparation for hyperosmotic stress and desiccation that begin at sunrise. These results suggest a conserved role for MAPK pathways in circadian rhythmicity...
  7. ncbi request reprint The rhythms of life: circadian output pathways in Neurospora
    Michael W Vitalini
    Center for Biological Clocks Research, Department of Biology, Texas A and M University, College Station, TX 77843, USA
    J Biol Rhythms 21:432-44. 2006
    ..The authors speculate that the clock system may sense not only light but also the redox potential of the cell through one of the PAS domains of the core clock components WC-1 or WC-2...
  8. pmc Circadian rhythms in Neurospora crassa and other filamentous fungi
    Yi Liu
    Department of Physiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9040, USA
    Eukaryot Cell 5:1184-93. 2006
  9. ncbi request reprint The Neurospora crassa pheromone precursor genes are regulated by the mating type locus and the circadian clock
    Piotr Bobrowicz
    Department of Plant Pathology and Microbiology, Texas A and M University, College Station 77843, USA
    Mol Microbiol 45:795-804. 2002
    ..Both pheromone precursor genes are also regulated by the endogenous circadian clock in a time-of-day-specific fashion, supporting a role for the clock in mating...
  10. pmc Assignment of an essential role for the Neurospora frequency gene in circadian entrainment to temperature cycles
    Antonio M Pregueiro
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Proc Natl Acad Sci U S A 102:2210-5. 2005
    ..Examination of several other phase markers as well as results of additional experimental tests indicate that the FLO is, at best, a slave oscillator to the TTFL, which underlies circadian rhythm generation in Neurospora...
  11. ncbi request reprint Circadian and light-induced expression of luciferase in Neurospora crassa
    Louis W Morgan
    Department of Biology, Texas A and M University, College Station, TX 77843 3258, USA
    Fungal Genet Biol 38:327-32. 2003
    ..These data demonstrate that luciferase is a sensitive reporter of gene expression in N. crassa. Our results also show that the modified luciferase is expressed in Aspergillus nidulans...
  12. pmc Distinct signaling pathways from the circadian clock participate in regulation of rhythmic conidiospore development in Neurospora crassa
    Alejandro Correa
    Department of Biology, Texas A and M University, College Station, Texas 77843, USA
    Eukaryot Cell 1:273-80. 2002
    ..Together, these data point to the endogenous clock and the environment following separate pathways to regulate conidiation-specific gene expression...
  13. ncbi request reprint Transcriptional response to glucose starvation and functional analysis of a glucose transporter of Neurospora crassa
    Xin Xie
    Program for the Biology of Filamentous Fungi, Department of Plant Pathology and Microbiology, Texas A and M University, College Station, TX 77843, USA
    Fungal Genet Biol 41:1104-19. 2004
    ..crassa. Transcripts of genes for ethanol fermentation and the tricarboxylic acid cycle are abundant in glucose-rich medium, consistent with N. crassa carrying out a high rate of both fermentation and respiration simultaneously...
  14. pmc A genetic selection for circadian output pathway mutations in Neurospora crassa
    Michael W Vitalini
    Center for Biological Clocks Research and Program for the Biology of Filamentous Fungi, Department of Biology, Texas A and M University, College Station, Texas 77843, USA
    Genetics 167:119-29. 2004
    ....
  15. pmc Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development
    Mari L Shinohara
    Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Eukaryot Cell 1:33-43. 2002
    ..Circadian control of trehalose synthase suggests a link between clock control of stress responses and that of development...
  16. pmc Multiple oscillators regulate circadian gene expression in Neurospora
    Alejandro Correa
    Center for Biological Clocks Research, Department of Biology, Texas A and M University, College Station, TX 77843, USA
    Proc Natl Acad Sci U S A 100:13597-602. 2003
    ..These ccgs accumulate mRNA rhythmically with a circadian period in a frq-null strain, confirming the existence of a second oscillator in N. crassa...
  17. ncbi request reprint Transcriptional profiling of the chick pineal gland, a photoreceptive circadian oscillator and pacemaker
    Michael J Bailey
    Department of Biology, Texas A and M University, College Station, Texas 77843 3258, USA
    Mol Endocrinol 17:2084-95. 2003
    ....
  18. ncbi request reprint The genome sequence of the filamentous fungus Neurospora crassa
    James E Galagan
    Whitehead Institute Center for Genome Research, 320 Charles Street, Cambridge, Massachusetts 02141, USA
    Nature 422:859-68. 2003
    ..Genome analysis suggests that RIP has had a profound impact on genome evolution, greatly slowing the creation of new genes through genomic duplication and resulting in a genome with an unusually low proportion of closely related genes...
  19. pmc A circadian oscillator in Aspergillus spp. regulates daily development and gene expression
    Andrew V Greene
    Program in Biological Clocks, Department of Biology Program in the Biology of Filamentous Fungi, Texas A and M University, College Station, Texas 77843, USA
    Eukaryot Cell 2:231-7. 2003
    ..Together, our data indicate the existence of an Aspergillus circadian clock, which has properties that differ from that of the well-described clock of N. crassa...
  20. pmc Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism
    Katherine A Borkovich
    Department of Plant Pathology, University of California, Riverside, California 92521, USA
    Microbiol Mol Biol Rev 68:1-108. 2004
    ..The group of unshared genes includes potential new targets for antifungals as well as loci implicated in human and plant physiology and disease...

Research Grants12

  1. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 1999
    ..Together, these experiments will permit a more detailed understanding of how the cell is organized as a function of time. ..
  2. Molecular Genetic Analysis of Fungal Circadian Rythms
    Deborah Bell Pedersen; Fiscal Year: 2009
    ..Understanding how the clock regulates the p38 pathway will facilitate efforts for developing new therapies for treating human diseases that result from clock dysfunction and/or misregulation of the p38 MAPK pathway. ..
  3. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2007
    ..Our studies will have a significant impact on understanding how circadian clocks control overt rhythmicity and will potentially provide novel approaches for therapies for human diseases that result from circadian dysfunction. ..
  4. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2006
    ..Our studies will have a significant impact on understanding how circadian clocks control overt rhythmicity and will potentially provide novel approaches for therapies for human diseases that result from circadian dysfunction. ..
  5. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2005
    ..Our studies will have a significant impact on understanding how circadian clocks control overt rhythmicity and will potentially provide novel approaches for therapies for human diseases that result from circadian dysfunction. ..
  6. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2004
    ..Our studies will have a significant impact on understanding how circadian clocks control overt rhythmicity and will potentially provide novel approaches for therapies for human diseases that result from circadian dysfunction. ..
  7. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2003
    ..Together, these experiments will permit a more detailed understanding of how the cell is organized as a function of time. ..
  8. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2002
    ..Together, these experiments will permit a more detailed understanding of how the cell is organized as a function of time. ..
  9. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2001
    ..Together, these experiments will permit a more detailed understanding of how the cell is organized as a function of time. ..
  10. MOLECULAR GENETIC ANALYSIS OF FUNGAL CIRCADIAN RHYTHMS
    Deborah Bell Pedersen; Fiscal Year: 2000
    ..Together, these experiments will permit a more detailed understanding of how the cell is organized as a function of time. ..
  11. Molecular Genetic Analysis of Fungal Circadian Rythms
    Deborah Bell Pedersen; Fiscal Year: 2010
    ..Understanding how the clock regulates the p38 pathway will facilitate efforts for developing new therapies for treating human diseases that result from clock dysfunction and/or misregulation of the p38 MAPK pathway. ..