Anjali Joshi

Summary

Affiliation: Texas Tech University Health Sciences Center
Country: USA

Publications

  1. pmc SNAREs in HIV-1 assembly
    Himanshu Garg
    Center of Excellence for Infectious Diseases Department of Biomedical Sciences Paul L Foster School of Medicine Texas Tech University Health Sciences Center El Paso, TX USA
    Commun Integr Biol 5:172-4. 2012
  2. pmc Identification of conserved motifs in the West Nile virus envelope essential for particle secretion
    Himanshu Garg
    Department of Biomedical Sciences, Texas Tech University Health Sciences Center, 5001 El Paso Dr, MSB 1 Annex, El Paso, TX 79905, USA
    BMC Microbiol 13:197. 2013
  3. pmc Targeting the HIV entry, assembly and release pathways for anti-HIV gene therapy
    Anjali Joshi
    Center of Excellence for Infectious Disease, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA
    Virology 415:95-106. 2011
  4. pmc Evidence of a role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) machinery in HIV-1 assembly and release
    Anjali Joshi
    Center of Excellence for Infectious Diseases, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, Texas 79905, USA
    J Biol Chem 286:29861-71. 2011
  5. ncbi request reprint Genetic signatures of HIV-1 envelope-mediated bystander apoptosis
    Anjali Joshi
    From the Center of Excellence for Infectious Diseases, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, Texas 79905
    J Biol Chem 289:2497-514. 2014
  6. pmc HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activity
    Anjali Joshi
    Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, Texas 79905, USA
    J Biol Chem 286:36404-13. 2011
  7. pmc HIV-1 induced bystander apoptosis
    Himanshu Garg
    Center of Excellence for Infectious Disease, Department of Biomedical Science, Texas Tech University Health Sciences Center, 5001 El Paso Dr, MSB 1 Annex, El Paso, TX 79905, USA
    Viruses 4:3020-43. 2012
  8. pmc Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice
    Himanshu Garg
    Center of Excellence for Infectious Disease, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, 5001 El Paso Drive, El Paso, Texas 79905, USA
    Virol J 8:34. 2011
  9. doi request reprint TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues
    Alice M Nyakeriga
    Department of Biomedical Sciences, Texas Tech University Health Sciences Center, 5001 El Paso Drive, El Paso, Texas 79905, USA
    Cytometry A 81:797-805. 2012
  10. ncbi request reprint Cardiovascular complications of HIV infection and treatment
    Himanshu Garg
    Center of Excellence for Infectious Disease, Department of Biomedical Science, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA
    Cardiovasc Hematol Agents Med Chem 11:58-66. 2013

Detail Information

Publications11

  1. pmc SNAREs in HIV-1 assembly
    Himanshu Garg
    Center of Excellence for Infectious Diseases Department of Biomedical Sciences Paul L Foster School of Medicine Texas Tech University Health Sciences Center El Paso, TX USA
    Commun Integr Biol 5:172-4. 2012
    ..Whether the observed phenomenon is specifically due to SNARE disruption or generalized disturbance of the cell sorting machinery and the involvement of specific "v" vs. "t" SNAREs in this phenomenon remains to be elucidated...
  2. pmc Identification of conserved motifs in the West Nile virus envelope essential for particle secretion
    Himanshu Garg
    Department of Biomedical Sciences, Texas Tech University Health Sciences Center, 5001 El Paso Dr, MSB 1 Annex, El Paso, TX 79905, USA
    BMC Microbiol 13:197. 2013
    ..We hence examined the West Nile Virus (WNV) Envelope protein for the presence of any such motifs and their functional characterization...
  3. pmc Targeting the HIV entry, assembly and release pathways for anti-HIV gene therapy
    Anjali Joshi
    Center of Excellence for Infectious Disease, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA
    Virology 415:95-106. 2011
    ..Finally, the Y164A/R515A double mutant expressed in a lentiviral vector was effective at inhibiting HIV replication in CD34+ hematopoietic stem cell-derived macrophages, demonstrating the therapeutic potential of our approach...
  4. pmc Evidence of a role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) machinery in HIV-1 assembly and release
    Anjali Joshi
    Center of Excellence for Infectious Diseases, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, Texas 79905, USA
    J Biol Chem 286:29861-71. 2011
    ..Our findings demonstrate for the first time a role of SNARE proteins in HIV-1 assembly and release, likely by affecting cellular trafficking pathways required for Gag transport and association with the plasma membrane...
  5. ncbi request reprint Genetic signatures of HIV-1 envelope-mediated bystander apoptosis
    Anjali Joshi
    From the Center of Excellence for Infectious Diseases, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, Texas 79905
    J Biol Chem 289:2497-514. 2014
    ..Furthermore, we identify specific genetic signatures within the Env that may be associated with the bystander apoptosis-inducing phenotype. ..
  6. pmc HIV ENV glycoprotein-mediated bystander apoptosis depends on expression of the CCR5 co-receptor at the cell surface and ENV fusogenic activity
    Anjali Joshi
    Department of Biomedical Sciences, Texas Tech University Health Sciences Center, El Paso, Texas 79905, USA
    J Biol Chem 286:36404-13. 2011
    ..Our findings suggest that R5 HIV-1-mediated bystander apoptosis is dependent on both CCR5 expression levels as well as fusogenic activity of the Env glycoprotein...
  7. pmc HIV-1 induced bystander apoptosis
    Himanshu Garg
    Center of Excellence for Infectious Disease, Department of Biomedical Science, Texas Tech University Health Sciences Center, 5001 El Paso Dr, MSB 1 Annex, El Paso, TX 79905, USA
    Viruses 4:3020-43. 2012
    ....
  8. pmc Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice
    Himanshu Garg
    Center of Excellence for Infectious Disease, Department of Biomedical Sciences, Texas Tech University Health Sciences Center, 5001 El Paso Drive, El Paso, Texas 79905, USA
    Virol J 8:34. 2011
    ..Whether the loss of CD4 cells is a direct consequence of virus infection or bystander apoptosis of uninfected cells is also uncertain...
  9. doi request reprint TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues
    Alice M Nyakeriga
    Department of Biomedical Sciences, Texas Tech University Health Sciences Center, 5001 El Paso Drive, El Paso, Texas 79905, USA
    Cytometry A 81:797-805. 2012
    ..Also, it is clear that cytometric analysis provides for a rapid, sensitive, and quantitative method to supplement biochemical studies on p56(lck) signaling pathways in T cells at single cell level...
  10. ncbi request reprint Cardiovascular complications of HIV infection and treatment
    Himanshu Garg
    Center of Excellence for Infectious Disease, Department of Biomedical Science, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA
    Cardiovasc Hematol Agents Med Chem 11:58-66. 2013
    ..In this review, we provide a summary of the mechanism of cardiovascular complications that are associated with HIV infection as well as long term treatment with HAART...
  11. doi request reprint Strategies for targeted nonviral delivery of siRNAs in vivo
    Sang Soo Kim
    Department of Biomedical Sciences, Center of Excellence for Infectious Diseases, Paul L Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA
    Trends Mol Med 15:491-500. 2009
    ..These approaches are expected to reduce the dose requirement as well as minimize siRNA-induced toxicities, thereby advancing the field of siRNA therapy towards clinical use...