S Howorka

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. ncbi Surface-accessible residues in the monomeric and assembled forms of a bacterial surface layer protein
    S Howorka
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, College Station, Texas 77843 1114, USA
    J Biol Chem 275:37876-86. 2000
  2. ncbi Sequence-specific detection of individual DNA strands using engineered nanopores
    S Howorka
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, 440 Reynolds Medical Building, College Station, TX 77843 1114, USA
    Nat Biotechnol 19:636-9. 2001
  3. ncbi Kinetics of duplex formation for individual DNA strands within a single protein nanopore
    S Howorka
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, 440 Reynolds Medical Building, College Station, TX 77843 1114, USA
    Proc Natl Acad Sci U S A 98:12996-3001. 2001
  4. ncbi Stochastic detection of monovalent and bivalent protein-ligand interactions
    Stefan Howorka
    The Texas A and M University System Health Science Center, Department of Medical Biochemistry and Genetics, 440 Reynolds Medical Building, College Station, TX 77843-1114, USA
    Angew Chem Int Ed Engl 43:842-6. 2004
  5. ncbi Location of a constriction in the lumen of a transmembrane pore by targeted covalent attachment of polymer molecules
    L Movileanu
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, College Station, Texas 77843, USA
    J Gen Physiol 117:239-52. 2001
  6. ncbi Protein components for nanodevices
    Yann Astier
    Department of Chemistry, University of Oxford, OX1 3TA, England, UK
    Curr Opin Chem Biol 9:576-84. 2005
  7. ncbi Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement
    Karel Drbal
    Competence Centre for Biomolecular Therapeutics Research Vienna, A 1090, Vienna
    Int Immunol 19:675-84. 2007
  8. ncbi Nanoscale protein pores modified with PAMAM dendrimers
    Hugh Martin
    Department of Chemistry, University College London, London WC1H 0AJ, England, United Kingdom
    J Am Chem Soc 129:9640-9. 2007
  9. ncbi Preparation and characterization of dense films of poly(amidoamine) dendrimers on indium tin oxide
    Robert Schlapak
    Center for Biomedical Nanotechnology, Upper Austrian Research GmbH, A 4020 Linz, Austria
    Langmuir 23:8916-24. 2007

Collaborators

  • H Bayley
  • O Braha
  • U B Sleytr
  • Y Wang
  • Franco Cacialli
  • Yann Astier
  • Karel Drbal
  • Hugh Martin
  • Robert Schlapak
  • L Movileanu
  • David Armitage
  • Christa Holzhauser
  • Michael Hohage
  • Helen Kinns
  • Manuel Moertelmaier
  • Hannes Stockinger
  • Yulia Samotskaya
  • Gerhard J Schütz
  • Hermann J Gruber
  • Nadia Saucedo-Zeni
  • Gianluca Latini
  • Arshad Muhammad
  • Nadia Saucedo Zeni
  • Nick Mitchell
  • Patrick Mesquida
  • Maria Hinterberger
  • Elke Fuertbauer
  • Rethi Madathil
  • S Cheley

Detail Information

Publications9

  1. ncbi Surface-accessible residues in the monomeric and assembled forms of a bacterial surface layer protein
    S Howorka
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, College Station, Texas 77843 1114, USA
    J Biol Chem 275:37876-86. 2000
    ..Together with other structural information, the results suggest a model for SbsB in which functional domains are segregated along the length of the polypeptide chain...
  2. ncbi Sequence-specific detection of individual DNA strands using engineered nanopores
    S Howorka
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, 440 Reynolds Medical Building, College Station, TX 77843 1114, USA
    Nat Biotechnol 19:636-9. 2001
    ..This was exemplified by the detection of a drug resistance-conferring mutation in the reverse transcriptase gene of HIV. In addition, the approach was used to sequence a complete codon in an individual DNA strand tethered to a nanopore...
  3. ncbi Kinetics of duplex formation for individual DNA strands within a single protein nanopore
    S Howorka
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, 440 Reynolds Medical Building, College Station, TX 77843 1114, USA
    Proc Natl Acad Sci U S A 98:12996-3001. 2001
    ..By investigating the temperature dependence of DNA duplex formation at the single molecule level, the standard enthalpy and entropy of the interaction could be obtained...
  4. ncbi Stochastic detection of monovalent and bivalent protein-ligand interactions
    Stefan Howorka
    The Texas A and M University System Health Science Center, Department of Medical Biochemistry and Genetics, 440 Reynolds Medical Building, College Station, TX 77843-1114, USA
    Angew Chem Int Ed Engl 43:842-6. 2004
  5. ncbi Location of a constriction in the lumen of a transmembrane pore by targeted covalent attachment of polymer molecules
    L Movileanu
    Department of Medical Biochemistry and Genetics, The Texas A and M University System Health Science Center, College Station, Texas 77843, USA
    J Gen Physiol 117:239-52. 2001
    ..The procedures described here should be applicable to other pores and to related structures such as the vestibules of ion channels...
  6. ncbi Protein components for nanodevices
    Yann Astier
    Department of Chemistry, University of Oxford, OX1 3TA, England, UK
    Curr Opin Chem Biol 9:576-84. 2005
    ....
  7. ncbi Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement
    Karel Drbal
    Competence Centre for Biomolecular Therapeutics Research Vienna, A 1090, Vienna
    Int Immunol 19:675-84. 2007
    ..A novel biochemical approach confirmed that lipid raft components are not associated in the plasma membrane of resting cells, and variably associate with specific receptors to distinct lipid rafts upon activation...
  8. ncbi Nanoscale protein pores modified with PAMAM dendrimers
    Hugh Martin
    Department of Chemistry, University College London, London WC1H 0AJ, England, United Kingdom
    J Am Chem Soc 129:9640-9. 2007
    ..The alteration of pore properties with charged and hyperbranched dendrimers is a new approach and might be extended to inorganic nanopores with applications in sensing and separation technology...
  9. ncbi Preparation and characterization of dense films of poly(amidoamine) dendrimers on indium tin oxide
    Robert Schlapak
    Center for Biomedical Nanotechnology, Upper Austrian Research GmbH, A 4020 Linz, Austria
    Langmuir 23:8916-24. 2007
    ..PAMAM-OH and Q-PAMAM-NH2 resulted in slightly smaller work function changes. This study illustrates that the work function of ITO can be tuned by adlayers composed of PAMAM dendrimers...