William Heird

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Rate of phenylalanine hydroxylation in healthy school-aged children
    Jean W Hsu
    Department of Pediatrics, USDA ARS Children s Nutrition Research Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Res 69:341-6. 2011
  2. ncbi request reprint Progress in promoting breast-feeding, combating malnutrition, and composition and use of infant formula, 1981-2006
    William C Heird
    Department of Pediatrics, Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    J Nutr 137:499S-502S. 2007
  3. ncbi request reprint Biochemical homeostasis and body growth are reliable end points in clinical nutrition trials
    William C Heird
    Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Nutr Soc 64:297-303. 2005
  4. ncbi request reprint The role of essential fatty acids in development
    William C Heird
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030 2600, USA
    Annu Rev Nutr 25:549-71. 2005
  5. pmc Taurine in neonatal nutrition--revisited
    W C Heird
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA
    Arch Dis Child Fetal Neonatal Ed 89:F473-4. 2004
  6. ncbi request reprint Lipids with an emphasis on long-chain polyunsaturated fatty acids
    Craig L Jensen
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA
    Clin Perinatol 29:261-81, vi. 2002
  7. ncbi request reprint Determination of nutritional requirements in preterm infants, with special reference to 'catch-up' growth
    W C Heird
    Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Semin Neonatol 6:365-75. 2001
  8. ncbi request reprint Biological effects and safety issues related to long-chain polyunsaturated fatty acids in infants
    W C Heird
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Lipids 34:207-14. 1999
  9. ncbi request reprint The role of polyunsaturated fatty acids in term and preterm infants and breastfeeding mothers
    W C Heird
    Department of Pediatrics, Section of Nutrition, USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA
    Pediatr Clin North Am 48:173-88. 2001
  10. ncbi request reprint Effect of docosahexaenoic acid supplementation of lactating women on the fatty acid composition of breast milk lipids and maternal and infant plasma phospholipids
    C L Jensen
    Department of Pediatrics, Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Clin Nutr 71:292S-9S. 2000

Research Grants

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Rate of phenylalanine hydroxylation in healthy school-aged children
    Jean W Hsu
    Department of Pediatrics, USDA ARS Children s Nutrition Research Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatr Res 69:341-6. 2011
    ..In conclusion, healthy children are capable of converting phenylalanine to tyrosine, but the need for tyrosine cannot be met by providing extra phenylalanine...
  2. ncbi request reprint Progress in promoting breast-feeding, combating malnutrition, and composition and use of infant formula, 1981-2006
    William C Heird
    Department of Pediatrics, Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    J Nutr 137:499S-502S. 2007
    ..Despite the progress that has been made in promoting breast-feeding and in the quality of infant formulas, further improvements in the duration of breast-feeding and in the composition of infant formulas are needed...
  3. ncbi request reprint Biochemical homeostasis and body growth are reliable end points in clinical nutrition trials
    William C Heird
    Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Nutr Soc 64:297-303. 2005
    ....
  4. ncbi request reprint The role of essential fatty acids in development
    William C Heird
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030 2600, USA
    Annu Rev Nutr 25:549-71. 2005
    ..However, evidence that preterm infants might benefit is somewhat more convincing than that for term infants. Despite the limited evidence for efficacy, formulas supplemented with DHA and ARA are now available and appear to be safe...
  5. pmc Taurine in neonatal nutrition--revisited
    W C Heird
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA
    Arch Dis Child Fetal Neonatal Ed 89:F473-4. 2004
  6. ncbi request reprint Lipids with an emphasis on long-chain polyunsaturated fatty acids
    Craig L Jensen
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA
    Clin Perinatol 29:261-81, vi. 2002
    ..Adequate intake of these fatty acids may be especially important for the preterm infant...
  7. ncbi request reprint Determination of nutritional requirements in preterm infants, with special reference to 'catch-up' growth
    W C Heird
    Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Semin Neonatol 6:365-75. 2001
    ..Firm data are limited, but those available suggest that current nutritional management of preterm infants can be improved. Whether this will have long-term benefits remains to be determined...
  8. ncbi request reprint Biological effects and safety issues related to long-chain polyunsaturated fatty acids in infants
    W C Heird
    Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Lipids 34:207-14. 1999
    ..In addition, since the symposium was held over 2 yr ago, an addendum summarizing additional data reported since the symposium that either support or refute issues discussed during the workshop also is included...
  9. ncbi request reprint The role of polyunsaturated fatty acids in term and preterm infants and breastfeeding mothers
    W C Heird
    Department of Pediatrics, Section of Nutrition, USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA
    Pediatr Clin North Am 48:173-88. 2001
    ..The safety of all available supplements is unknown; however, some trials reveal few reasons for major concerns about the safety of single-cell oils, low-EPA fish oil, or egg-yolk phospholipid or triglyceride fractions...
  10. ncbi request reprint Effect of docosahexaenoic acid supplementation of lactating women on the fatty acid composition of breast milk lipids and maternal and infant plasma phospholipids
    C L Jensen
    Department of Pediatrics, Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Clin Nutr 71:292S-9S. 2000
    ..Breast-milk and maternal and infant PP 22:5n-6 concentrations were lowest in group 2. DHA supplementation increases the plasma and breast-milk DHA concentrations of lactating women, resulting in higher PP DHA concentrations in infants...
  11. ncbi request reprint Cholesterol-lowering effect of soy protein in normocholesterolemic and hypercholesterolemic men
    W W Wong
    US Department of Agriculture ARS Children s Nutrition Research Center, The Department of Pediatrics, Baylor College of Medicine, Houston 77030, USA
    Am J Clin Nutr 68:1385S-1389S. 1998
    ..005). Our results indicate that soy protein enhances the hypocholesterolemic effect of the NCEP Step I diet in both normocholesterolemic and hypercholesterolemic men...
  12. ncbi request reprint Relationship between omega3 long-chain polyunsaturated fatty acid status during early infancy and neurodevelopmental status at 1 year of age
    R G Voigt
    Meyer Center for Developmental Pediatrics, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    J Hum Nutr Diet 15:111-20. 2002
    ....
  13. ncbi request reprint Maternal response to two electric breast pumps
    Judy Hopkinson
    Department of Pediatrics, USDA ARS Children s Nutrition Research Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Breastfeed Med 4:17-23. 2009
    ..This study evaluated the impact of a novel pump design on milk extraction, milk fat content, maternal hormone response, maternal satisfaction, long-term milk production, and duration of breastfeeding following return to the workforce...
  14. pmc Bicarbonate kinetics and predicted energy expenditure in critically ill children
    Jama Sy
    Critical Care Section, Department of Pediatrics, Texas Children s Hospital, Baylor College of Medicine, Houston, TX, USA
    Am J Clin Nutr 88:340-7. 2008
    ..Energy expenditure can be determined by bicarbonate dilution kinetics if the energy equivalents of carbon dioxide (food quotient) from the diet ingested are known...
  15. ncbi request reprint Dietary fat has minimal effects on fatty acid metabolism transcript concentrations in pigs
    S T Ding
    USDA, ARS, Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030 2600, USA
    J Anim Sci 81:423-31. 2003
    ..Also, in porcine adipose tissue, as well as in liver and skeletal muscle, these transcripts are rather refractory to modification by dietary FA...
  16. ncbi request reprint Urinary F2-isoprostanes are poor prognostic indicators for the development of bronchopulmonary dysplasia
    S D Reuter
    Department of Pediatrics, Section of Neonatology, Baylor College of Medicine, Houston, TX, USA
    J Perinatol 27:303-6. 2007
    ..Oxidant injury leads to formation of F(2)-isoprostanes (F(2)-IsoP). We hypothesized that urinary excretion of the stable metabolite of F(2)-IsoP, 8-iso-PGF(2alpha), would be higher in infants who develop BPD than those who did not...
  17. pmc Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein
    Benny Hung Junn Chang
    Division of Diabetes, Endocrinology, and Metabolism, Departments of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Mol Cell Biol 26:1063-76. 2006
    ..In the absence of ADFP, impairment of LD formation is associated with the accumulation of microsomal TG but a reduction in TG in other subcellular compartments...
  18. pmc Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis
    Jianqiang Mao
    The Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Department of Molecular and Cell Biology, Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 103:8552-7. 2006
    ..Hence, reducing cytosolic malonyl-CoA and, therefore, the de novo fatty acid synthesis in the liver, does not affect fatty acid oxidation and glucose homeostasis under lipogenic conditions...
  19. ncbi request reprint Body-composition assessment in infancy: air-displacement plethysmography compared with a reference 4-compartment model
    Kenneth J Ellis
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Clin Nutr 85:90-5. 2007
    ..A better understanding of the associations of early infant nutrition and growth with adult health requires accurate assessment of body composition in infancy...
  20. ncbi request reprint The fatty acid profile of buccal cheek cell phospholipids is a noninvasive marker of long-chain polyunsaturated Fatty Acid status in piglets
    Alexandre Lapillonne
    U S Department of Agriculture ARS Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030 2600, USA
    J Nutr 132:2319-23. 2002
    ....
  21. ncbi request reprint Infant feeding and vision
    William C Heird
    Am J Clin Nutr 87:1120. 2008
  22. ncbi request reprint Current electrolyte intakes of infants and toddlers
    William C Heird
    Children s Nutrition Research Center, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA
    J Am Diet Assoc 106:S43-51. 2006
    ..To determine how sodium, chloride, and potassium intakes of today's infants and toddlers compare with the Dietary Reference Intakes (DRIs) of these nutrients established recently by the Food and Nutrition Board of the Institute of Medicine...
  23. ncbi request reprint Plausible mechanisms for effects of long-chain polyunsaturated fatty acids on growth
    Alexandre Lapillonne
    Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    J Pediatr 143:S9-16. 2003
    ..Furthermore, although additional data are needed for a definitive conclusion, the observed effects on growth, regardless of mechanism, does not appear to be biologically significant...
  24. ncbi request reprint Effect of maternal docosahexaenoic acid supplementation on postpartum depression and information processing
    Antolin M Llorente
    Department of Pediatrics, United States Department of Agriculture, Agricultural Research Service Children s Nutrition Research Center, Houston, TX, USA
    Am J Obstet Gynecol 188:1348-53. 2003
    ..The purpose of this study was to determine the effect of docosahexaenoic acid supplementation on plasma phospholipid docosahexaenoic acid content and indices of depression and information processing for women who breast-feed...
  25. ncbi request reprint Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment in breastfed term infants
    Craig L Jensen
    US Department of Agriculture Agricultural Research Service Children s Nutrition Research Center and the Meyer Center for Developmental Pediatrics, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Clin Nutr 82:125-32. 2005
    ..Because the supplementation of breastfeeding mothers with DHA increases the DHA content of their infants' plasma lipids, we hypothesized that it might also improve brain or visual function in the infants...
  26. ncbi request reprint Protein and energy requirements of the preterm/low birthweight (LBW) infant
    Patti Thureen
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver 80262, USA
    Pediatr Res 57:95R-98R. 2005
  27. ncbi request reprint The protein metabolic response to HIV infection in young children
    Farook Jahoor
    US Department of Agriculture, Agricultural Research Service, Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Clin Nutr 78:182-9. 2003
    ..However, the protein metabolic response elicited by the virus in young children is unknown...
  28. ncbi request reprint Concurrent and predictive validity of the cognitive adaptive test/clinical linguistic and auditory milestone scale (CAT/CLAMS) and the Mental Developmental Index of the Bayley Scales of Infant Development
    Robert G Voigt
    Division of Developmental and Behavioral Pediatrics, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Clin Pediatr (Phila) 42:427-32. 2003
    ....
  29. ncbi request reprint Circadian rhythms in myocardial metabolism and contractile function: influence of workload and oleate
    David J Durgan
    United States Department of Agriculture Agricultural Research Service Children s Nutrition Research Center, Department of Pediatrics, Houston, Texas, USA
    Am J Physiol Heart Circ Physiol 293:H2385-93. 2007
    ..In conclusion, these studies expose marked circadian rhythmicities in myocardial oxidative and nonoxidative metabolism as well as responsiveness of the rat heart to changes in workload and fatty acid availability...
  30. ncbi request reprint Comparison of the validity of direct pediatric developmental evaluation versus developmental screening by parent report
    Robert G Voigt
    Division of Developmental and Behavioral Pediatrics, Mayo Clinic, Rochester, Minnesota55905, USA
    Clin Pediatr (Phila) 46:523-9. 2007
    ..Increased emphasis on training of pediatric health care providers in direct developmental evaluation should be considered...
  31. pmc Omega-3 long-chain polyunsaturated fatty acids in older children
    William C Heird
    J Pediatr 150:457-9. 2007
  32. ncbi request reprint Cysteine supplementation improves the erythrocyte glutathione synthesis rate in children with severe edematous malnutrition
    Asha Badaloo
    Tropical Metabolism Research Unit, University of the West Indies, Kingston, Jamaica
    Am J Clin Nutr 76:646-52. 2002
    ....
  33. ncbi request reprint Polyunsaturated fatty acids and gene expression
    Alexandre Lapillonne
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Curr Opin Clin Nutr Metab Care 7:151-6. 2004
    ....
  34. ncbi request reprint Parental feeding behavior and children's fat mass
    William C Heird
    Am J Clin Nutr 75:451-2. 2002
  35. ncbi request reprint Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema
    Marvin Reid
    Tropical Metabolism Research Unit, University of the West Indies, Mona, Kingston 7, Jamaica
    J Nutr 134:3004-10. 2004
    ..These findings are consistent with the hypothesis that the blunting of the protein catabolic response to infection in children with edematous malnutrition syndrome is due to limited availability of aromatic amino acids...
  36. ncbi request reprint Response of splanchnic and whole-body leucine kinetics to treatment of children with edematous protein-energy malnutrition accompanied by infection
    Marvin Reid
    US Department of Agriculture, Agricultural Research Service, Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Am J Clin Nutr 76:633-40. 2002
    ....
  37. ncbi request reprint The acute-phase protein response to infection in edematous and nonedematous protein-energy malnutrition
    Marvin Reid
    US Department of Agriculture, Agricultural Research Service, Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Am J Clin Nutr 76:1409-15. 2002
    ..Immune structure and function are more compromised in edematous protein-energy malnutrition (PEM) than in nonedematous PEM. Whether the positive acute-phase protein (APP) response to infection is affected remains unknown...

Research Grants3

  1. DIETARY OMEGA-3 FATTY ACIDS, GENE EXPRESSION AND GROWTH
    William Heird; Fiscal Year: 2001
    ..abstract_text> ..
  2. Impact of Development on Protein Utilization and Growth
    William Heird; Fiscal Year: 2007
    ..Overall, the findings of this project are expected to contribute to further improvements in nutritional management and, hence, outcome of LBW infants. ..
  3. RESEARCH TRAINING IN MATERNAL, INFANT & CHILD NUTRITION
    William Heird; Fiscal Year: 2008
    ..abstract_text> ..