Lan Guan

Summary

Affiliation: Texas Tech University Health Sciences Center
Country: USA

Publications

  1. pmc Role of Gly117 in the cation/melibiose symport of MelB of Salmonella typhimurium
    Lan Guan
    Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    Biochemistry 51:2950-7. 2012
  2. pmc Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium
    Lan Guan
    Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 286:6367-74. 2011
  3. pmc Reduced Na+ affinity increases turnover of Salmonella enterica serovar Typhimurium MelB
    S Vivek Jakkula
    Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
    J Bacteriol 194:5538-44. 2012

Collaborators

  • S Vivek Jakkula

Detail Information

Publications3

  1. pmc Role of Gly117 in the cation/melibiose symport of MelB of Salmonella typhimurium
    Lan Guan
    Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    Biochemistry 51:2950-7. 2012
    ..Taken together, the findings are consistent with the notion that Gly117 plays an important role in cation binding and translocation...
  2. pmc Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium
    Lan Guan
    Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Biol Chem 286:6367-74. 2011
    ....
  3. pmc Reduced Na+ affinity increases turnover of Salmonella enterica serovar Typhimurium MelB
    S Vivek Jakkula
    Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
    J Bacteriol 194:5538-44. 2012
    ..Thus, the P148L mutation specifically inhibits transport velocity and thereby blocks the lethal effect of elevated melibiose transport in the Gly117 mutants...

Research Grants1

  1. Novel capture reagents for membrane protein structure determination
    Lan Guan; Fiscal Year: 2010
    ..The approach proposed here can serve as a general tool to enhance the probability of crystallization of membrane proteins and thereby facilitate their structure determination. ..