Ernest A Gonzalez

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis
    Ernest A Gonzalez
    Department of Surgery, The University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Trauma 59:1092-8. 2005
  2. ncbi request reprint Conventional dose hypertonic saline provides optimal gut protection and limits remote organ injury after gut ischemia reperfusion
    Ernest A Gonzalez
    Department of Surgery, The University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Trauma 61:66-73; discussion 73-4. 2006
  3. doi request reprint Performance of a computerized protocol for trauma shock resuscitation
    Joseph F Sucher
    Department of Surgery, The Methodist Hospital, 6550 Fannin Street, Smith Tower 1661A, Houston, TX 77030, USA
    World J Surg 34:216-22. 2010
  4. ncbi request reprint Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2
    James W Suliburk
    Department of Surgery, The University of Texas Medical School at Houston, 77030, USA
    Surgery 138:134-40. 2005
  5. ncbi request reprint Ketamine inhibits lipopolysacharide (LPS) induced gastric luminal fluid accumulation
    James W Suliburk
    Department of General Surgery, The University of Texas Medical School at Houston, Houston, Texas 77026, USA
    J Surg Res 127:203-7. 2005
  6. doi request reprint Gastric alkalinization after major trauma
    Christine S Cocanour
    Department of Surgery, UC Davis Medical Center, Sacramento, California, USA
    J Trauma 64:681-7. 2008
  7. doi request reprint Poloxamer 188 prolongs survival of hypotensive resuscitation and decreases vital tissue injury after full resuscitation
    Rongzhen Zhang
    Department of Pathology, University of Texas Houston Medical School, Houston, Texas, USA
    Shock 32:442-50. 2009
  8. doi request reprint Early cytokine production risk stratifies trauma patients for multiple organ failure
    Kenneth M Jastrow
    Department of Surgery, University of Texas Medical School at Houston, Houston, TX
    J Am Coll Surg 209:320-31. 2009
  9. ncbi request reprint Fresh frozen plasma should be given earlier to patients requiring massive transfusion
    Ernest A Gonzalez
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas, USA
    J Trauma 62:112-9. 2007
  10. ncbi request reprint Early predictors of prolonged mechanical ventilation in major torso trauma patients who require resuscitation
    Steven C Agle
    Department of Surgery, Eastern Carolina University, Greenville, NC, USA
    Am J Surg 192:822-7. 2006

Detail Information

Publications21

  1. ncbi request reprint Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis
    Ernest A Gonzalez
    Department of Surgery, The University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Trauma 59:1092-8. 2005
    ..In contrast to I/R cell necrosis, apoptosis provides controlled cell death that minimizes inflammation. We therefore hypothesized that HS resuscitation after mesenteric I/R would induce apoptosis and decrease mucosal injury...
  2. ncbi request reprint Conventional dose hypertonic saline provides optimal gut protection and limits remote organ injury after gut ischemia reperfusion
    Ernest A Gonzalez
    Department of Surgery, The University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Trauma 61:66-73; discussion 73-4. 2006
    ..We hypothesized that a dose dependent effect exists related to increasing tonicity and that the optimal gut protective dose would provide better protection against remote organ injury than large volume isotonic crystalloids...
  3. doi request reprint Performance of a computerized protocol for trauma shock resuscitation
    Joseph F Sucher
    Department of Surgery, The Methodist Hospital, 6550 Fannin Street, Smith Tower 1661A, Houston, TX 77030, USA
    World J Surg 34:216-22. 2010
    ....
  4. ncbi request reprint Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2
    James W Suliburk
    Department of Surgery, The University of Texas Medical School at Houston, 77030, USA
    Surgery 138:134-40. 2005
    ..Because ketamine anesthesia has anti-inflammatory effects in some tissues, we hypothesized that it would attenuate lipopolysaccharide (LPS)-induced liver injury...
  5. ncbi request reprint Ketamine inhibits lipopolysacharide (LPS) induced gastric luminal fluid accumulation
    James W Suliburk
    Department of General Surgery, The University of Texas Medical School at Houston, Houston, Texas 77026, USA
    J Surg Res 127:203-7. 2005
    ..The purpose of this study was to determine if the anti-inflammatory properties of ketamine improve impaired gastric emptying and gastrointestinal transit because of LPS...
  6. doi request reprint Gastric alkalinization after major trauma
    Christine S Cocanour
    Department of Surgery, UC Davis Medical Center, Sacramento, California, USA
    J Trauma 64:681-7. 2008
    ..Therefore, we hypothesized that trauma patients have an alkaline gastric environment that may be because of bile reflux...
  7. doi request reprint Poloxamer 188 prolongs survival of hypotensive resuscitation and decreases vital tissue injury after full resuscitation
    Rongzhen Zhang
    Department of Pathology, University of Texas Houston Medical School, Houston, Texas, USA
    Shock 32:442-50. 2009
    ..Because P188 prolongs survival, decreases fluid requirements, and reduces tissue damage, it deserves further consideration as an adjunct to hypotensive resuscitation...
  8. doi request reprint Early cytokine production risk stratifies trauma patients for multiple organ failure
    Kenneth M Jastrow
    Department of Surgery, University of Texas Medical School at Houston, Houston, TX
    J Am Coll Surg 209:320-31. 2009
    ..In animal models of hemorrhagic shock, early (< 24 hours) changes in cytokine production are an index of the systemic inflammatory response syndrome. However, their predictive value in trauma patients remains to be fully elucidated...
  9. ncbi request reprint Fresh frozen plasma should be given earlier to patients requiring massive transfusion
    Ernest A Gonzalez
    Department of Surgery, University of Texas Houston Medical School, Houston, Texas, USA
    J Trauma 62:112-9. 2007
    ..The hypothesis for this study is that our pre-intensive care unit (ICU) massive transfusion (MT) protocol does not adequately correct coagulopathy, and that early uncorrected coagulopathy is predictive of mortality...
  10. ncbi request reprint Early predictors of prolonged mechanical ventilation in major torso trauma patients who require resuscitation
    Steven C Agle
    Department of Surgery, Eastern Carolina University, Greenville, NC, USA
    Am J Surg 192:822-7. 2006
    ..The study purpose was to identify early predictors of prolonged mechanical ventilation in major torso trauma patients...
  11. doi request reprint Central venous pressure versus pulmonary artery catheter-directed shock resuscitation
    Bruce A McKinley
    Department of Surgery, The Methodist Hospital and The Methodist Hospital Research Institute, Houston, Texas 77030, USA
    Shock 32:463-70. 2009
    ..Computerized decision support provides a technique to implement complex protocol care processes and analyze patient response...
  12. pmc Modulation of syndecan-1 shedding after hemorrhagic shock and resuscitation
    Ricky J Haywood-Watson
    Department of Surgery, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
    PLoS ONE 6:e23530. 2011
    ..These data suggest that plasma based resuscitation preserved endothelial syndecan-1 and maintained endothelial integrity, and may help to explain the protective effects of fresh frozen plasma after hemorrhagic shock...
  13. doi request reprint Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients
    John B Holcomb
    United States Army Institute of Surgical Research, Ft Sam Houston, TX 78234, USA
    Ann Surg 248:447-58. 2008
    ....
  14. doi request reprint Effects of poloxamer 188 on human PMN cells
    Matthew T Harting
    Department of Pediatric Surgery, University of Texas Medical School, Houston, TX 77030, USA
    Surgery 144:198-203. 2008
    ..We studied human PMN oxidative burst and adhesion molecule expression when exposed to P188...
  15. doi request reprint Defining the limits of resuscitative emergency department thoracotomy: a contemporary Western Trauma Association perspective
    Ernest E Moore
    Department of Surgery, Denver Health, Denver, Colorado 80204, USA
    J Trauma 70:334-9. 2011
    ..The purpose of this prospective multicenter study was to identify injury patterns and physiologic profiles at ED arrival that are compatible with survival...
  16. pmc Update on postinjury nutrition
    Samuel R Todd
    Department of Surgery, The Methodist Hospital Weill Cornell Medical College, USA
    Curr Opin Crit Care 14:690-5. 2008
    ..The optimal utilization and benefit of pharmaconutrients, however, remains unclear, as does the need for full caloric provision in the early postinjury phase...
  17. doi request reprint Resuscitation beyond the abdominal compartment syndrome
    Ernest A Gonzalez
    aThe University of Texas Southwestern at Austin, Austin bThe Methodist Hospital at Houston, Houston, Texas, USA
    Curr Opin Crit Care 16:570-4. 2010
    ....
  18. ncbi request reprint A multidisciplinary clinical pathway decreases rib fracture-associated infectious morbidity and mortality in high-risk trauma patients
    S Rob Todd
    Department of Surgery, The Methodist Hospital, 6550 Fannin Street, Smith Tower 1661, Houston, TX 77030, USA
    Am J Surg 192:806-11. 2006
    ..The purpose of the current study was to evaluate the effect of this pathway on infectious morbidity and mortality...
  19. ncbi request reprint Differential effects of anesthetics on endotoxin-induced liver injury
    James W Suliburk
    Department of Surgery, The University of Texas Medical School at Houston, Houston, Texas, USA
    J Trauma 58:711-6; discussion 716-7. 2005
    ..We hypothesized that ketamine, but not isoflurane, would attenuate lipopolysaccharide (LPS)-induced liver injury through differential modulation of iNOS and HO-1...
  20. ncbi request reprint Acute lower extremity compartment syndrome (ALECS) screening protocol in critically ill trauma patients
    Roman Kosir
    Department of Surgery, General and Teaching Hospital, Maribor, Slovenia
    J Trauma 63:268-75. 2007
    ..Acute lower extremity compartment syndrome (ALECS) is a devastating complication that often presents silently in critically injured patients; therefore, we developed a protocol to screen high-risk patients...
  21. ncbi request reprint Damage control resuscitation: directly addressing the early coagulopathy of trauma
    John B Holcomb
    USAISR, Fort Sam Houston, TX 78234 6315, USA
    J Trauma 62:307-10. 2007