F S Gimble
Affiliation: Texas A and M University
- Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic centerF S Gimble
Center for Macromolecular Design, Institute of Biosciences and Technology and Department of Biochemistry and Biophysics, Texas A and M University, Houston, Texas 77030, USA
J Biol Chem 273:30524-9. 1998..The presence of similar basic and acidic residues in many LAGLIDADG homing endonucleases suggests that these enzymes use a common reaction mechanism to cleave double-stranded DNA...
- Putting protein splicing to workF S Gimble
Center for Macromolecular Design, Texas A and M University, Houston, Texas 77030, USA
Chem Biol 5:R251-6. 1998..Now, new methods have been developed, based on the same chemical reactions, that permit proteins to be modified in ways that were not previously possible...
- Degeneration of a homing endonuclease and its target sequence in a wild yeast strainF S Gimble
Center for Genome Research, Institute of Biosciences and Technology, Texas A and M University System Health Science Center, 2121 West Holcombe Boulevard, Texas A and M University, Houston, TX 77030, USA
Nucleic Acids Res 29:4215-23. 2001..Loss of activity in the DH1-1A endonuclease and target site provides one explanation for co-existence of the intein(+) and intein(-) alleles...