RICHARD EUGENE FRYE

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Linear coding of voice onset time
    Richard E Frye
    University of Texas Health Science Center at Houston, TX 77030, USA
    J Cogn Neurosci 19:1476-87. 2007
  2. doi request reprint Leber's hereditary optic neuropathy mutations associated with infantile-onset myoclonic epilepsy
    Richard E Frye
    Division of Child and Adolescent Neurology, Department of Pediatrics, and Children s Learning Institute, University of Texas Health Science Center, Houston, TX 77030, USA
    J Child Neurol 26:782-5. 2011
  3. pmc Mitochondrial dysfunction can connect the diverse medical symptoms associated with autism spectrum disorders
    Richard E Frye
    Department of Pediatrics, The Children s Learning Institute, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Pediatr Res 69:41R-7R. 2011
  4. doi request reprint Diffusion tensor quantification of the relations between microstructural and macrostructural indices of white matter and reading
    Richard E Frye
    Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Health Science Center, 7000 Fannin, Houston, TX 77030, USA
    Hum Brain Mapp 32:1220-35. 2011
  5. pmc Tetrahydrobiopterin as a novel therapeutic intervention for autism
    Richard E Frye
    Division of Child and Adolescent Neurology and The Children s Learning Institute, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Neurotherapeutics 7:241-9. 2010
  6. pmc Greater Pre-Stimulus Effective Connectivity from the Left Inferior Frontal Area to other Areas is Associated with Better Phonological Decoding in Dyslexic Readers
    Richard E Frye
    Department of Pediatrics, Division of Child and Adolescent Neurology and The Children s Learning Institute, University of Texas Health Science Center Houston, TX, USA
    Front Syst Neurosci 4:156. 2010
  7. pmc Central tetrahydrobiopterin concentration in neurodevelopmental disorders
    Richard E Frye
    Department of Pediatrics, Division of Child and Adolescent Neurology and The Children s Learning Institute, University of Texas Health Science Center Houston, TX, USA
    Front Neurosci 4:52. 2010
  8. doi request reprint Multichannel least-squares linear regression provides a fast, accurate, unbiased and robust estimation of Granger causality for neurophysiological data
    Richard E Frye
    Arkansas Children s Hospital Research Institute, University of Arkansas Medical Sciences, Little Rock, AR 72202, USA
    Comput Biol Med 41:1118-31. 2011
  9. pmc Objective phonological and subjective perceptual characteristics of syllables modulate spatiotemporal patterns of superior temporal gyrus activity
    Richard E Frye
    Division of Child and Adolescent Neurology, University of Texas Health Science Center at Houston, Houston, TX, USA
    Neuroimage 40:1888-901. 2008
  10. doi request reprint Preterm birth and maternal responsiveness during childhood are associated with brain morphology in adolescence
    Richard E Frye
    Department of Pediatrics, University of Texas Health Science Center, Houston, Texas 77030, USA
    J Int Neuropsychol Soc 16:784-94. 2010

Research Grants

Detail Information

Publications25

  1. pmc Linear coding of voice onset time
    Richard E Frye
    University of Texas Health Science Center at Houston, TX 77030, USA
    J Cogn Neurosci 19:1476-87. 2007
    ....
  2. doi request reprint Leber's hereditary optic neuropathy mutations associated with infantile-onset myoclonic epilepsy
    Richard E Frye
    Division of Child and Adolescent Neurology, Department of Pediatrics, and Children s Learning Institute, University of Texas Health Science Center, Houston, TX 77030, USA
    J Child Neurol 26:782-5. 2011
    ....
  3. pmc Mitochondrial dysfunction can connect the diverse medical symptoms associated with autism spectrum disorders
    Richard E Frye
    Department of Pediatrics, The Children s Learning Institute, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Pediatr Res 69:41R-7R. 2011
    ..This new understanding of ASD should provide researchers a pathway for understanding the etiopathogenesis of ASD and clinicians the potential to develop medical therapies...
  4. doi request reprint Diffusion tensor quantification of the relations between microstructural and macrostructural indices of white matter and reading
    Richard E Frye
    Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Health Science Center, 7000 Fannin, Houston, TX 77030, USA
    Hum Brain Mapp 32:1220-35. 2011
    ..Changes in macrostructure paralleled changes in microstructure. We conclude that the relations between several microstructural indices and factors related to reading ability are different for association and projection pathways...
  5. pmc Tetrahydrobiopterin as a novel therapeutic intervention for autism
    Richard E Frye
    Division of Child and Adolescent Neurology and The Children s Learning Institute, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Neurotherapeutics 7:241-9. 2010
    ....
  6. pmc Greater Pre-Stimulus Effective Connectivity from the Left Inferior Frontal Area to other Areas is Associated with Better Phonological Decoding in Dyslexic Readers
    Richard E Frye
    Department of Pediatrics, Division of Child and Adolescent Neurology and The Children s Learning Institute, University of Texas Health Science Center Houston, TX, USA
    Front Syst Neurosci 4:156. 2010
    ..Overly strong gamma connectivity during the pre-stimulus period may interfere with subsequent transient activation and deactivation of sub-networks once the non-word appears...
  7. pmc Central tetrahydrobiopterin concentration in neurodevelopmental disorders
    Richard E Frye
    Department of Pediatrics, Division of Child and Adolescent Neurology and The Children s Learning Institute, University of Texas Health Science Center Houston, TX, USA
    Front Neurosci 4:52. 2010
    ..These data suggests that central BH(4) concentration may be related to systemic inflammation and oxidative stress pathways...
  8. doi request reprint Multichannel least-squares linear regression provides a fast, accurate, unbiased and robust estimation of Granger causality for neurophysiological data
    Richard E Frye
    Arkansas Children s Hospital Research Institute, University of Arkansas Medical Sciences, Little Rock, AR 72202, USA
    Comput Biol Med 41:1118-31. 2011
    ....
  9. pmc Objective phonological and subjective perceptual characteristics of syllables modulate spatiotemporal patterns of superior temporal gyrus activity
    Richard E Frye
    Division of Child and Adolescent Neurology, University of Texas Health Science Center at Houston, Houston, TX, USA
    Neuroimage 40:1888-901. 2008
    ..Moreover, our results demonstrate that both objective phonological and subjective perceptual characteristics of syllables independently modulate spatiotemporal patterns of cortical activation...
  10. doi request reprint Preterm birth and maternal responsiveness during childhood are associated with brain morphology in adolescence
    Richard E Frye
    Department of Pediatrics, University of Texas Health Science Center, Houston, Texas 77030, USA
    J Int Neuropsychol Soc 16:784-94. 2010
    ....
  11. pmc Increased left prefrontal activation during an auditory language task in adolescents born preterm at high risk
    Richard E Frye
    Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Health Science Center, Houston, TX, USA
    Brain Res 1336:89-97. 2010
    ..We suggest that this increased prefrontal activation may represent increased top-down control of weak posterior language networks...
  12. pmc Electroencephalogram discharges in atypical cognitive development
    Richard E Frye
    Department of Pediatrics, Division of Child and Adolescent Neurology, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Child Neurol 25:556-66. 2010
    ..This study suggests that children with developmental cognitive disorders that do not respond to standard therapy may benefit from screening with an EEG and a trial of antiepileptic mediation if discharges are detected...
  13. pmc Superior longitudinal fasciculus and cognitive dysfunction in adolescents born preterm and at term
    Richard E Frye
    Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA
    Dev Med Child Neurol 52:760-6. 2010
    ..To understand the relationship between cognition and white-matter structure in adolescents born preterm without obvious brain injury...
  14. pmc Transcranial magnetic stimulation in child neurology: current and future directions
    Richard E Frye
    Department of Pediatrics, Division of Child Neurology, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    J Child Neurol 23:79-96. 2008
    ..Given its excellent safety profile and possible therapeutic effect, this technique should develop as an important tool in pediatric neurology over the next decade...
  15. pmc Increased prefrontal activation in adolescents born prematurely at high risk during a reading task
    Richard E Frye
    Division of Child and Adolescent Neurology, University of Texas Health Science Center, Houston, TX 77030, USA
    Brain Res 1303:111-9. 2009
    ..These results suggest a reorganization of the prefrontal cortex in adolescents born prematurely at high-risk...
  16. pmc 15q11.2-13 duplication, mitochondrial dysfunction, and developmental disorders
    Richard E Frye
    Department of Pediatrics and Neurology, Division of Child and Adolescent Neurology, University of Texas Health Science Center, Houston, Texas, USA
    J Child Neurol 24:1316-20. 2009
    ..In light of the frequency of this duplication in children with developmental dishabilles, the wider implication of the association between this duplication and mitochondrial dysfunction needs to be considered...
  17. pmc Executive dysfunction in poor readers born prematurely at high risk
    Richard E Frye
    Division of Child and Adolescent Neurology and The Children s Learning Institute, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Dev Neuropsychol 34:254-71. 2009
    ..These data suggest that better reading ability is associated with better neuropsychological function independent of prematurity...
  18. pmc Receptive language organization in high-functioning autism
    Richard E Frye
    Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    J Child Neurol 24:231-6. 2009
    ..We discuss common mechanisms that may account for cognitive delays across these developmental disorders...
  19. pmc Splenium microstructure is related to two dimensions of reading skill
    Richard E Frye
    Department of Pediatrics, University of Texas Health Science Center, 7000 Fannin UCT 2478, Houston, TX 77030, USA
    Neuroreport 19:1627-31. 2008
    ..Phonological awareness was positively associated with splenium FA and LA in TRs but not DRs. This study suggests two white matter pathways that may be differentially associated with reading skills in the CC splenium...
  20. pmc Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey
    Richard E Frye
    Department of Pediatrics, University of Texas Health Science Center, Houston, USA
    BMC Pediatr 11:37. 2011
    ..In order to determine the effectiveness of traditional and non-traditional treatments for improving seizures and influencing other clinical factor relevant to ASD, we developed a comprehensive on-line seizure survey...
  21. pmc Surface area accounts for the relation of gray matter volume to reading-related skills and history of dyslexia
    Richard E Frye
    Division of Child and Adolescent Neurology, Department of Pediatrics, University of Texas Health Science Center, Houston, TX 77030, USA
    Cereb Cortex 20:2625-35. 2010
    ..This study demonstrates the importance of examining the separate components of gray matter volume when studying developmental abnormalities...
  22. ncbi request reprint Information communication networks in severe traumatic brain injury
    Luca Pollonini
    Biomedical Imaging Lab, Department of Engineering Technology, University of Houston, 218 Philip G Hoffman Hall, Houston, TX, 77204 3058, USA
    Brain Topogr 23:221-6. 2010
    ..The results of this study suggest that analysis of brain connectivity networks based on GC can be a highly accurate approach for classifying subjects affected by severe traumatic brain injury...
  23. pmc Touch, sound and vision in human superior temporal sulcus
    Michael S Beauchamp
    Department of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA
    Neuroimage 41:1011-20. 2008
    ..We conclude that STSms is important for integrating information from the somatosensory as well as the auditory and visual modalities, and could be the human homolog of macaque STP...
  24. doi request reprint Diffusion tensor-based regional gray matter tissue segmentation using the international consortium for brain mapping atlases
    Khader M Hasan
    Department of Diagnostic and Interventional Imaging, University of Texas Medical School at Houston, Houston, Texas, USA
    Hum Brain Mapp 32:107-17. 2011
    ..In the future, this new approach can be automated to analyze large data sets to help discover noninvasive neuroimaging markers for clinical trials and brain-function studies in both health and disease...
  25. pmc Choroid plexus papilloma expansion over 7 years in Aicardi syndrome
    Richard E Frye
    Department of Pediatrics, Division of Pediatric Neurology, University of Texas Health Science Center, Houston, Texas 77030, USA
    J Child Neurol 22:484-7. 2007
    ..The tumor was removed without change in behavior or development. The known cases of Aicardi syndrome associated with choroid plexus papillomas are reviewed. The heterogeneous nature of this lesion is highlighted...

Research Grants2

  1. Developmental Phonological Dyslexia: Neural Mechanisms
    Richard Frye; Fiscal Year: 2007
    ..In addition, the insight provided by this research will help guide the development of improved methods of diagnosis, rehabilitation, treatment and long-term monitoring of individuals with developmental cognitive disorders. ..