Daniel I Feig

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Hyperuricemia in childhood primary hypertension
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    Hypertension 42:247-52. 2003
  2. ncbi request reprint Uric acid and hypertension
    Daniel I Feig
    Department of Pediatrics, Renal Section, MC3 2482, Baylor College of Medicine, 1102 Bates Street, Houston, TX 77030, USA
    Curr Hypertens Rep 8:111-5. 2006
  3. ncbi request reprint Serum uric acid: a risk factor and a target for treatment?
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    J Am Soc Nephrol 17:S69-73. 2006
  4. pmc Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    JAMA 300:924-32. 2008
  5. pmc Uric acid and cardiovascular risk
    Daniel I Feig
    Baylor College of Medicine, Houston, TX 77030, USA
    N Engl J Med 359:1811-21. 2008
  6. ncbi request reprint Uric acid and hypertension in adolescents
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    Semin Nephrol 25:32-8. 2005
  7. ncbi request reprint Hypothesis: Uric acid, nephron number, and the pathogenesis of essential hypertension
    Daniel I Feig
    Renal Section, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    Kidney Int 66:281-7. 2004
  8. pmc The role of uric acid in pediatric hypertension
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, Texas 77030, USA
    J Ren Nutr 17:79-83. 2007
  9. doi request reprint Uric acid reduction rectifies prehypertension in obese adolescents
    Beth Soletsky
    Baylor College of Medicine, Department of Pediatrics, Renal Section, Houston, TX, USA
    Hypertension 60:1148-56. 2012
  10. doi request reprint Cost-effectiveness of ambulatory blood pressure monitoring in the initial evaluation of hypertension in children
    Sarah J Swartz
    Department of Pediatrics, Renal Section, Baylor College of Medicine, 6621 Fannin St, MC3 2482, Houston, TX 77030, USA
    Pediatrics 122:1177-81. 2008

Research Grants

  1. Primary Prevention of Hypertension in Obese Adolescents
    Daniel Feig; Fiscal Year: 2006
  2. Uric Acid in Childhood Hypertension
    Daniel Feig; Fiscal Year: 2007

Detail Information

Publications27

  1. pmc Hyperuricemia in childhood primary hypertension
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    Hypertension 42:247-52. 2003
    ..These results are consistent with the hypothesis that uric acid might have a role in the early pathogenesis of primary hypertension...
  2. ncbi request reprint Uric acid and hypertension
    Daniel I Feig
    Department of Pediatrics, Renal Section, MC3 2482, Baylor College of Medicine, 1102 Bates Street, Houston, TX 77030, USA
    Curr Hypertens Rep 8:111-5. 2006
    ..Ongoing clinical trials will elucidate the role of uric acid in human hypertension and will determine whether control of uric acid may be a new way to prevent or treat essential hypertension...
  3. ncbi request reprint Serum uric acid: a risk factor and a target for treatment?
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    J Am Soc Nephrol 17:S69-73. 2006
    ..Although the investigations are still preliminary, serum uric acid represents a possible new and intriguing target for the reduction of morbidity and mortality associated with hypertension and CV disease...
  4. pmc Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    JAMA 300:924-32. 2008
    ..Experimentally increasing uric acid levels using a uricase inhibitor causes systemic hypertension in animal models...
  5. pmc Uric acid and cardiovascular risk
    Daniel I Feig
    Baylor College of Medicine, Houston, TX 77030, USA
    N Engl J Med 359:1811-21. 2008
  6. ncbi request reprint Uric acid and hypertension in adolescents
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA
    Semin Nephrol 25:32-8. 2005
    ....
  7. ncbi request reprint Hypothesis: Uric acid, nephron number, and the pathogenesis of essential hypertension
    Daniel I Feig
    Renal Section, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
    Kidney Int 66:281-7. 2004
    ..Genetic, physiologic, and epidemiologic studies provide clues to its origins, but a clear understanding has been elusive. Recent experimental and clinical studies have implicated uric acid in the onset of essential hypertension...
  8. pmc The role of uric acid in pediatric hypertension
    Daniel I Feig
    Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, Texas 77030, USA
    J Ren Nutr 17:79-83. 2007
    ..Future studies will be needed to determine whether the mechanisms shown in animal models can be extrapolated to children...
  9. doi request reprint Uric acid reduction rectifies prehypertension in obese adolescents
    Beth Soletsky
    Baylor College of Medicine, Department of Pediatrics, Renal Section, Houston, TX, USA
    Hypertension 60:1148-56. 2012
    ..These data indicate that, at least in adolescents with prehypertension, uric acid causes increased BP that can be mitigated by urate lowering therapy...
  10. doi request reprint Cost-effectiveness of ambulatory blood pressure monitoring in the initial evaluation of hypertension in children
    Sarah J Swartz
    Department of Pediatrics, Renal Section, Baylor College of Medicine, 6621 Fannin St, MC3 2482, Houston, TX 77030, USA
    Pediatrics 122:1177-81. 2008
    ..The goal was to determine the cost-effectiveness of ambulatory blood pressure monitoring in the initial evaluation of stage 1 hypertension...
  11. pmc Uric acid: a novel mediator and marker of risk in chronic kidney disease?
    Daniel I Feig
    Baylor College of Medicine and Texas Children s Hospital, Houston, Texas 77030, USA
    Curr Opin Nephrol Hypertens 18:526-30. 2009
    ..To assess the current data suggesting that uric acid-lowering therapy may be useful in the prevention or mitigation of chronic kidney disease (CKD)...
  12. doi request reprint Hyperuricemia and hypertension
    Daniel I Feig
    Division of Nephrology, Department of Pediatrics, University of Alabama, Birmingham, AL 35233, USA
    Adv Chronic Kidney Dis 19:377-85. 2012
    ..Although more research is clearly necessary, the available data suggest that uric acid is likely causative in some cases of early onset hypertension...
  13. doi request reprint Association between left ventricular mass index and cardiac function in pediatric dialysis patients
    Pirouz Shamszad
    Department of Pediatrics, Lillie Frank Abercrombie Section of Cardiology, Baylor College of Medicine, 6621 Fannin St, MC 19345 C, Houston, 77030, TX, USA
    Pediatr Nephrol 27:835-41. 2012
    ..LVMI has not been linked to cardiovascular endpoints in children. The aim of this study was to identify an association between elevated LVMI and echocardiographic markers of systolic and diastolic function...
  14. doi request reprint The role of uric acid in the pathogenesis of hypertension in the young
    Daniel I Feig
    Division of Nephrology, Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, Birmingham, AL 35233, USA
    J Clin Hypertens (Greenwich) 14:346-52. 2012
    ..While more research is clearly necessary, the available data suggest that uric acid is likely causative in some cases of early-onset hypertension...
  15. doi request reprint Uric acid and hypertension
    Daniel I Feig
    Division of Nephrology, Department of Pediatrics, University of Alabama, Birmingham School of Medicine, Birmingham, AL 35233, USA
    Semin Nephrol 31:441-6. 2011
    ..Initial clinical trials in young patients have supported these mechanisms in young patients but do not yet support pharmacologic reduction of serum uric acid as first-line therapy for hypertension...
  16. doi request reprint Safety and efficacy of intravenous labetalol for hypertensive crisis in infants and small children
    Christopher A Thomas
    Department of Pharmacy, Texas Children s Hospital, Houston, Texas, USA
    Pediatr Crit Care Med 12:28-32. 2011
    ..To determine the efficacy and safety of labetalol for hypertensive crisis in children ≤ 24 months of age...
  17. doi request reprint Sugar-sweetened beverages and hypertension
    Daniel I Feig
    Baylor College of Medicine, 1102 Bates Street, Ste 260, Houston, TX 77030, USA
    Future Cardiol 6:773-6. 2010
    ..8 mmHg reduction in systolic blood pressure and an average of 1.1 mmHg reduction in diastolic blood pressure...
  18. ncbi request reprint Frequent hemodialysis with NxStage system in pediatric patients receiving maintenance hemodialysis
    Stuart L Goldstein
    Department of Pediatrics, Renal, Baylor College of Medicine, Houston, TX, USA
    Pediatr Nephrol 23:129-35. 2008
    ..Variable changes in proinflammatory cytokine levels were observed. We suggest that frequent HD with the NxStage system be considered for children who would benefit from home-based maintenance dialysis...
  19. doi request reprint Minimal change disease with IgM+ immunofluorescence: a subtype of nephrotic syndrome
    Sarah J Swartz
    Renal Division, Department of Pediatrics, Baylor College of Medicine, 6621 Fannin St, MC3 2482, Houston, TX 77030, USA
    Pediatr Nephrol 24:1187-92. 2009
    ..IgM+ IF may be surrogate marker for the severity of MCD. Based on our results, children with MCD and IgM+ IF have a better response to cyclosporine than cyclophosphamide...
  20. ncbi request reprint Inaccuracy in pediatric outpatient blood pressure measurement
    Amber Podoll
    Cardiology Section, Baylor College of Medicine, Houston, TX 77030, USA
    Pediatrics 119:e538-43. 2007
    ..quot;..
  21. ncbi request reprint Childhood hypertension is not a silent disease
    Beth Croix
    Renal Section, Department of Pediatrics, Baylor College of Medicine and Texas Children s Hospital, Houston, TX 77030, USA
    Pediatr Nephrol 21:527-32. 2006
    ..001). We conclude that newly diagnosed hypertensive children had a variety of non-specific symptoms, more prevalent than those of normotensive children, and most somatic complaints improved with 4-6 months of anti-hypertensive treatment...
  22. ncbi request reprint Diuretic-induced hyperuricemia does not decrease cardiovascular risk
    Titte R Srinivas
    J Hypertens 22:1415-7; author reply 1417-9. 2004
  23. ncbi request reprint Does asymptomatic hyperuricaemia contribute to the development of renal and cardiovascular disease? An old controversy renewed
    John Kanellis
    Department of Nephrology, University of Melbourne, Austin Health, Melbourne, Australia
    Nephrology (Carlton) 9:394-9. 2004
    ..How clarification of the role of uric acid may guide future treatment strategies will also be discussed...
  24. ncbi request reprint Nephron number, uric acid, and renal microvascular disease in the pathogenesis of essential hypertension
    Daniel I Feig
    Hypertension 48:25-6. 2006
  25. ncbi request reprint Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease
    Richard J Johnson
    Division of Nephrology and Department of Medicine, University of Florida, Gainesville, FL, USA
    Am J Clin Nutr 86:899-906. 2007
    ..Finally, we suggest that high intakes of fructose in African Americans may explain their greater predisposition to develop cardiorenal disease, and we provide a list of testable predictions to evaluate this hypothesis...
  26. ncbi request reprint A unifying pathway for essential hypertension
    Richard J Johnson
    Division of Nephrology, Hypertension and Transplantation, PO Box 100224, University of Florida, Gainesville, FL 32610, USA
    Am J Hypertens 18:431-40. 2005
    ..This pathway unites many of the previous hypotheses on the etiology of hypertension, and offers insights into ways to prevent, ameliorate, or cure the underlying process...
  27. ncbi request reprint A causal role for uric acid in fructose-induced metabolic syndrome
    Takahiko Nakagawa
    Division of Nephrology, Hypertension, and Transplantation, PO Box 100224, University of Florida, Gainesville, FL 32610, USA
    Am J Physiol Renal Physiol 290:F625-31. 2006
    ..Fructose may have a major role in the epidemic of metabolic syndrome and obesity due to its ability to raise uric acid...

Research Grants3

  1. Primary Prevention of Hypertension in Obese Adolescents
    Daniel Feig; Fiscal Year: 2006
    ....
  2. Uric Acid in Childhood Hypertension
    Daniel Feig; Fiscal Year: 2007
    ..abstract_text> ..