H El-Serag

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint The association between diabetes and hepatocellular carcinoma: a systematic review of epidemiologic evidence
    Hashem B El-Serag
    Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center at Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 4:369-80. 2006
  2. ncbi request reprint Prevalence and determinants of histological abnormalities of the gastric cardia in volunteers
    Hashem B El-Serag
    Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Scand J Gastroenterol 42:1158-66. 2007
  3. doi request reprint Prevalence and histological features of the gastric cardia-type mucosa in children
    Hashem B El-Serag
    Section of Gastroenterology, Houston Center for Quality of Care and Utilization Studies, The Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Dig Dis Sci 53:1792-6. 2008
  4. doi request reprint Role of obesity in GORD-related disorders
    Hashem El-Serag
    Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Gut 57:281-4. 2008
  5. ncbi request reprint Temporal trends in new and recurrent oesophageal strictures in a Medicare population
    H B El-Serag
    Section of Gastroenterology, The Houston Department of Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX, USA
    Aliment Pharmacol Ther 25:1223-9. 2007
  6. doi request reprint The extent and determinants of prescribing and adherence with acid-reducing medications: a national claims database study
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Houston Center for Quality of Care and Utilization Studies, The Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Gastroenterol 104:2161-7. 2009
  7. ncbi request reprint Time trends of gastroesophageal reflux disease: a systematic review
    Hashem B El-Serag
    Gastroenterology and Health Services Research Sections, Michael E DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 5:17-26. 2007
  8. pmc Obesity increases oesophageal acid exposure
    Hashem B El-Serag
    Section of Health Services Research, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Gut 56:749-55. 2007
  9. ncbi request reprint The prevalence of suspected Barrett's esophagus in children and adolescents: a multicenter endoscopic study
    Hashem B El-Serag
    The Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Gastrointest Endosc 64:671-5. 2006
  10. ncbi request reprint Anthropometric correlates of intragastric pressure
    Hashem B El-Serag
    Sections of Health Services Research and Gastroenterology, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Scand J Gastroenterol 41:887-91. 2006

Detail Information

Publications87

  1. ncbi request reprint The association between diabetes and hepatocellular carcinoma: a systematic review of epidemiologic evidence
    Hashem B El-Serag
    Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center at Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 4:369-80. 2006
    ..We conducted a systematic review and a meta-analysis to estimate the magnitude and determinants of association between diabetes and hepatocellular carcinoma (HCC)...
  2. ncbi request reprint Prevalence and determinants of histological abnormalities of the gastric cardia in volunteers
    Hashem B El-Serag
    Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Scand J Gastroenterol 42:1158-66. 2007
    ..There have been no studies on non-patient populations. The aim of this study was to mitigate the potential effects of selection bias...
  3. doi request reprint Prevalence and histological features of the gastric cardia-type mucosa in children
    Hashem B El-Serag
    Section of Gastroenterology, Houston Center for Quality of Care and Utilization Studies, The Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Dig Dis Sci 53:1792-6. 2008
    ..We examined the presence and determinants of gastric cardia-type mucosa at a normally located z-line in children without underlying gastroesophageal reflux disease (GERD)-predisposing disorders...
  4. doi request reprint Role of obesity in GORD-related disorders
    Hashem El-Serag
    Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Gut 57:281-4. 2008
    ..Maintaining normal weight may reduce the likelihood of developing GORD and its potential complications...
  5. ncbi request reprint Temporal trends in new and recurrent oesophageal strictures in a Medicare population
    H B El-Serag
    Section of Gastroenterology, The Houston Department of Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX, USA
    Aliment Pharmacol Ther 25:1223-9. 2007
    ..The temporal trends of strictures have not been examined in population-based studies...
  6. doi request reprint The extent and determinants of prescribing and adherence with acid-reducing medications: a national claims database study
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Houston Center for Quality of Care and Utilization Studies, The Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Gastroenterol 104:2161-7. 2009
    ..No community-based, large-scale studies have examined the extent of prescribing acid-reducing medications or adherence and persistence to these medication regimens...
  7. ncbi request reprint Time trends of gastroesophageal reflux disease: a systematic review
    Hashem B El-Serag
    Gastroenterology and Health Services Research Sections, Michael E DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 5:17-26. 2007
    ..If this trend continues, it could contribute to the rapidly increasing incidence of more serious complications associated with GERD, such as esophageal adenocarcinoma, as well as costs to healthcare systems and employers...
  8. pmc Obesity increases oesophageal acid exposure
    Hashem B El-Serag
    Section of Health Services Research, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Gut 56:749-55. 2007
    ..Obesity has been associated with gastro-oesophageal reflux disease (GERD); however, the mechanism by which obesity may cause GERD is unclear...
  9. ncbi request reprint The prevalence of suspected Barrett's esophagus in children and adolescents: a multicenter endoscopic study
    Hashem B El-Serag
    The Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Gastrointest Endosc 64:671-5. 2006
    ..The prevalence of Barrett's esophagus (BE) in young individuals is unclear...
  10. ncbi request reprint Anthropometric correlates of intragastric pressure
    Hashem B El-Serag
    Sections of Health Services Research and Gastroenterology, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Scand J Gastroenterol 41:887-91. 2006
    ..However, the association between anthropometric measures of total body as well as abdominal obesity and intragastric pressure has not been examined...
  11. ncbi request reprint Treatment and outcomes of treating of hepatocellular carcinoma among Medicare recipients in the United States: a population-based study
    Hashem B El-Serag
    Section of Health Services Research, Houston Veterans Affairs Medical Center, Baylor College of Medicine, 2002 Holcombe Boulevard 152, Houston, TX 77030, USA
    J Hepatol 44:158-66. 2006
    ..Yet, neither the extent to which potentially curative or palliative therapy is used to treat HCC, nor the determinants of using such therapies are known. Further, it is unclear how effective different modalities are for treating HCC...
  12. ncbi request reprint Obesity and disease of the esophagus and colon
    Hashem B El-Serag
    Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center at Baylor College of Medicine, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Gastroenterol Clin North Am 34:63-82. 2005
    ..This article discusses the evidence linking obesity to the different manifestations of gastroesophageal reflux disease and colorectal cancer...
  13. ncbi request reprint Survival in hepatitis C and HIV co-infection: a cohort study of hospitalized veterans
    Hashem B El-Serag
    Houston Center for Quality of Care and Utilization Studies, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas, USA
    Clin Gastroenterol Hepatol 3:175-83. 2005
    ..However, the long-term effect of hepatitis C virus (HCV) co-infection on the mortality of HIV-infected patients remains unclear...
  14. ncbi request reprint Management of the single liver nodule in a cirrhotic patient: a decision analysis model
    Hashem B El-Serag
    Sections of Gastroenterology, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX 77030, USA
    J Clin Gastroenterol 39:152-9. 2005
    ..The long waiting time prior to OLT limits its advantage over surgical resection in the treatment of patients with early HCC...
  15. doi request reprint The use of acid-decreasing medication in veteran patients with gastro-oesophageal reflux disorder with and without Barrett's oesophagus
    H B El-Serag
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Aliment Pharmacol Ther 27:1293-9. 2008
    ..To examine use of acid-decreasing medications, especially proton pump inhibitors (PPIs), in patients with gastro-oesophageal reflux disorder (GERD) with and without Barrett's oesophagus (BO) in a large-scale study...
  16. doi request reprint The utility of evaluating low serum albumin gradient ascites in patients with cirrhosis
    Hashim E Khandwalla
    Sections of Gastroenterology and Health Services Research, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Gastroenterol 104:1401-5. 2009
    ..However, the predictive value of a low SAAG in patients with existing cirrhosis in whom the pretest probability of portal hypertension is high is not clear...
  17. doi request reprint Diagnosis and treatment of hepatocellular carcinoma
    Hashem B El-Serag
    Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 134:1752-63. 2008
    ..In this article, we present a summary of the most recent information on screening, diagnosis, staging, and different treatment modalities of HCC, as well as our recommended management approach...
  18. pmc The association between obesity and GERD: a review of the epidemiological evidence
    Hashem El-Serag
    The Sections of Gastroenterology and Health Services Research, The Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Dig Dis Sci 53:2307-12. 2008
    ..Overall, epidemiological data show that maintaining a normal BMI may reduce the likelihood of developing GERD and its potential complications...
  19. doi request reprint Systematic review: the epidemiology of gastro-oesophageal reflux disease in primary care, using the UK General Practice Research Database
    H El-Serag
    Michael E DeBakey Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Aliment Pharmacol Ther 29:470-80. 2009
    ..Gastro-oesophageal reflux disease (GERD) is a common diagnosis in primary care; however, there has been no comprehensive review of the epidemiology of GERD in this setting...
  20. pmc Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: A population-based study of U.S. veterans
    Hashem B El-Serag
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    Hepatology 49:116-23. 2009
    ..Absence of an association with ECC was consistent in adjusted and unadjusted models. A significant association with pancreatic cancer was erased by alcohol use and other variables...
  21. ncbi request reprint Epidemiology of hepatocellular carcinoma in Hispanics in the United States
    Hashem B El-Serag
    Section of Gastroenterology, The Houston Veterans Affairs Medical Center, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Arch Intern Med 167:1983-9. 2007
    ..In previous studies, the rates for Hispanics have not been reported separately from other racial or ethnic groups...
  22. pmc Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes
    Hashem B El-Serag
    Section of Gastroenterology at the Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 136:1601-8. 2009
    ..Given the increasing prevalence of statin use, and the increasing incidence of hepatocellular carcinoma (HCC), the potential association between statins and HCC is an important issue to examine...
  23. pmc Gene expression in Barrett's esophagus: laser capture versus whole tissue
    Hashem B El-Serag
    Michael E DeBakey Veterans Administration Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Scand J Gastroenterol 44:787-95. 2009
    ..The purpose of this study was to determine the degree of overlap of the two sample types and to define a set of genes that might serve as biochemical markers for BE...
  24. ncbi request reprint Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    Hashem B El-Serag
    Michael E DeBakey Veterans Administration Medical Center and Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Houston, Texas, USA
    Gastroenterology 132:2557-76. 2007
    ..A detailed understanding of epidemiologic factors and molecular mechanisms associated with HCC ultimately could improve our current concepts for screening and treatment of this disease...
  25. ncbi request reprint Determinants of gastroesophageal reflux disease in adults with a history of childhood gastroesophageal reflux disease
    Hashem B El-Serag
    Section of Health Services Research, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas 77030, USA
    Clin Gastroenterol Hepatol 5:696-701. 2007
    ..We conducted a nested case-control study to examine the prevalence and risk factors for current gastroesophageal reflux disease (GERD) symptoms in young adults with a history of childhood GERD...
  26. pmc Dietary intake and the risk of gastro-oesophageal reflux disease: a cross sectional study in volunteers
    H B El-Serag
    Section of Gastroenterology and Health Services Research, The Houston Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Gut 54:11-7. 2005
    ..We examined associations of GORD symptoms with intakes of specific dietary components...
  27. doi request reprint Systematic review: persistent reflux symptoms on proton pump inhibitor therapy in primary care and community studies
    H El-Serag
    Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    Aliment Pharmacol Ther 32:720-37. 2010
    ..Persistent gastro-oesophageal reflux disease (GERD) symptoms can occur despite proton pump inhibitor (PPI) therapy...
  28. ncbi request reprint Hepatocellular carcinoma: recent trends in the United States
    Hashem B El-Serag
    The Houston Veterans Affairs Medical Center 152, 2002 Holcombe Boulevard, Houston, Texas 77030, USA
    Gastroenterology 127:S27-34. 2004
    ..The insulin resistance syndrome, manifesting as obesity and diabetes, is emerging as a risk factor for HCC in the United States; however, its impact on the current trend in HCC remains unclear...
  29. ncbi request reprint Health-related quality of life in functional dyspepsia
    H B El-Serag
    Section of Gastroenterology, The Houston Veterans Affairs Medical Center and the Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA
    Aliment Pharmacol Ther 18:387-93. 2003
    ..We performed a systematic review of the literature to compare the health-related quality of life (HRQOL) of patients with functional dyspepsia with either healthy controls or those with other diseases...
  30. ncbi request reprint Extrahepatic manifestations of hepatitis C among United States male veterans
    Hashem B El-Serag
    Section of Gastroenterology and Section of Health Services Research at The Houston Veterans Affairs Medical Center, Houston, TX, USA
    Hepatology 36:1439-45. 2002
    ..In conclusion, we found a significant association between HCV infection and PCT, lichen planus, vitiligo, cryoglobulinemia, membranoproliferative GN, and NHL. Patients presenting with these disorders should be tested for HCV infection...
  31. ncbi request reprint Hepatocellular carcinoma and hepatitis C in the United States
    Hashem B El-Serag
    Sections of Gastroenterology and Health Services Research at the Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, 77030, USA
    Hepatology 36:S74-83. 2002
    ..Future research should focus on improving understanding of the incidence and risk factors for HCC, causes of HCV-related carcinogenesis, means of early detection, and better treatment for HCC...
  32. ncbi request reprint Prevention of complicated ulcer disease among chronic users of nonsteroidal anti-inflammatory drugs: the use of a nomogram in cost-effectiveness analysis
    Hashem B El-Serag
    Health Services Research Sections, Houston Center for Quality of Care and Utilization Studies, Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Arch Intern Med 162:2105-10. 2002
    ..Our objective in this study was to compare the cost-effectiveness of several strategies aimed at reducing the risk of clinical UGI events in NSAID users...
  33. ncbi request reprint Risk factors for the severity of erosive esophagitis in Helicobacter pylori-negative patients with gastroesophageal reflux disease
    H B El-Serag
    Gastroenterology and Health Services Research, Houston VA Medical Center, Baylor College of Medicine, Texas 77030, USA
    Scand J Gastroenterol 37:899-904. 2002
    ..The risk factors for the varying grades of erosive esophagitis (EE) severity could be better understood. For that reason. we evaluated the risk factors associated with EE in patients with gastroesophageal reflux disease...
  34. ncbi request reprint The epidemic of esophageal adenocarcinoma
    Hashem B El-Serag
    Sections of Gastroenterology and Health Services Research, Houston Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX, USA
    Gastroenterol Clin North Am 31:421-40, viii. 2002
    ....
  35. ncbi request reprint Diabetes increases the risk of acute hepatic failure
    Hashem B El-Serag
    Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center, Texas 77030, USA
    Gastroenterology 122:1822-8. 2002
    ..It is unclear whether patients with diabetes are at an increased risk of developing acute liver failure (ALF). We performed a large cohort study to examine the occurrence of ALF by using the databases of the Department of Veterans Affairs...
  36. ncbi request reprint Health-related quality of life among persons with irritable bowel syndrome: a systematic review
    H B El-Serag
    Sections of Gastroenterology and Health Services Research, Houston Veterans Affairs Medical Center 152, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Aliment Pharmacol Ther 16:1171-85. 2002
    ....
  37. pmc Epidemiological differences between adenocarcinoma of the oesophagus and adenocarcinoma of the gastric cardia in the USA
    H B El-Serag
    Section of Gastroenterology, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas77030, USA
    Gut 50:368-72. 2002
    ..We examined several epidemiological features of GCA and OA in the USA to elucidate differences/similarities between these malignancies...
  38. ncbi request reprint Extraesophageal associations of gastroesophageal reflux disease in children without neurologic defects
    H B El-Serag
    Section of Gastroenterology, Houston Veterans Affairs Medical Center 152, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Gastroenterology 121:1294-9. 2001
    ..We conducted a large case-control study to examine the association between GERD and several upper and lower respiratory disorders in these children...
  39. ncbi request reprint Epidemiology of hepatocellular carcinoma
    H B El-Serag
    Sections of Gastroenterology and Health Services Research, Houston VA Medical Center, and Baylor College of Medicine, Houston, Texas, USA
    Clin Liver Dis 5:87-107, vi. 2001
    ..The incidence and mortality of HCC has been rising in the US over the last two decades and is progressively affecting younger persons. The evidence indicates that HCV infection is responsible for the current trends...
  40. ncbi request reprint Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States
    H B El-Serag
    Section of Gastroenterology, The Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Hepatology 33:62-5. 2001
    ..Most of this apparent benefit is restricted to the first year following cancer diagnosis, raising the possibility of lead-time bias. There were no significant differences related to gender or ethnicity...
  41. ncbi request reprint Risk factors for the rising rates of primary liver cancer in the United States
    H B El-Serag
    Houston VA Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Arch Intern Med 160:3227-30. 2000
    ..A recent increase in the incidence of hepatocellular carcinoma was reported in the United States. The cause of this witnessed rise remains unknown...
  42. ncbi request reprint The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update
    Hashem B El-Serag
    The Houston Center for Quality of Care and Utilization Studies, Sections of Gastroenterology and Health Services Research at The Houston Veterans Affairs Medical Center, and Baylor College of Medicine, Houston, Texas 77030, USA
    Ann Intern Med 139:817-23. 2003
    ..The incidence of hepatocellular carcinoma was reported to be increasing in the United States. However, alternate explanations were diagnostic or reclassification bias and changes in the demographic features of the general population...
  43. ncbi request reprint Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    Hashem B El-Serag
    Section of Gastroenterology, Houston Departmentof Veterans Affais Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    Gastroenterology 126:460-8. 2004
    ..An association between diabetes and chronic liver disease has been reported. However, the temporal relationship between these conditions remains unknown...
  44. ncbi request reprint The use of screening colonoscopy for patients cared for by the Department of Veterans Affairs
    Hashem B El-Serag
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX 77030, USA
    Arch Intern Med 166:2202-8. 2006
    ..Because of differences in the delivery of health care, this trend in use of colonoscopy in fee-for-service settings might not be paralleled in the Department of Veterans Affairs (VA)...
  45. ncbi request reprint The length of newly diagnosed Barrett's oesophagus and prior use of acid suppressive therapy
    H B El-Serag
    Section of Gastroenterology, The Houston, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Aliment Pharmacol Ther 19:1255-60. 2004
    ..However, it remains unknown whether prior acid suppressive therapy affects the length of newly diagnosed Barrett's oesophagus...
  46. ncbi request reprint Gastroesophageal reflux among different racial groups in the United States
    Hashem B El-Serag
    Section of Gastroenterology, Houston Department of Veterans Affairs Medical Center 152, 2002 Holcombe Boulevard, Houston, TX 77030, USA
    Gastroenterology 126:1692-9. 2004
    ..It remains unknown whether this racial discrepancy reflects a higher prevalence of gastroesophageal reflux disease (GERD) symptoms or a higher degree of esophageal damage...
  47. ncbi request reprint Systemic review: Natural history of irritable bowel syndrome
    H B El-Serag
    Division of Gastroenterology, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    Aliment Pharmacol Ther 19:861-70. 2004
    ..Understanding the stability of an irritable bowel syndrome diagnosis may limit repeated diagnostic evaluation among these patients...
  48. ncbi request reprint Is the length of newly diagnosed Barrett's esophagus decreasing? The experience of a VA Health Care System
    Hashem B El-Serag
    Section of Gastroenterology, Houston VA Medical Center, and Baylor College of Medicine, Texas 77030, USA
    Clin Gastroenterol Hepatol 2:296-300. 2004
    ..Secular trends in the length of newly diagnosed Barrett's esophagus (BE) are unknown. We have anecdotally noticed less frequent new diagnoses of long segments of BE...
  49. ncbi request reprint Systemic review: the prevalence and clinical course of functional dyspepsia
    H B El-Serag
    Sections of Gastroenterology and Health Services Research, Houston Veterans Affairs Medical Center, and Baylor College of Medicine, Houston, TX, USA
    Aliment Pharmacol Ther 19:643-54. 2004
    ..To examine the prevalence of functional dyspepsia in the general population, and to evaluate the natural history/clinical course of patients with functional dyspepsia...
  50. ncbi request reprint Is fibrolamellar carcinoma different from hepatocellular carcinoma? A US population-based study
    Hashem B El-Serag
    Section of Health Services Research, The Houston Veterans Affairs Medical Center and Baylor College of Medicine, 2002 Holcombe Boulevard 152, Houston, TX 77030, USA
    Hepatology 39:798-803. 2004
    ..In conclusion, in a population-based study, we observed remarkable differences in the epidemiology and prognosis of FLC compared to HCC...
  51. ncbi request reprint Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: a hospital-based case-control study
    Yasser H Shaib
    The Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 102:1016-21. 2007
    ..We evaluated hepatitis C virus (HCV), hepatitis B virus (HBV), and liver cirrhosis as risk factors for intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC)...
  52. ncbi request reprint The use of cytokeratin stain to distinguish Barrett's esophagus from contiguous tissues: a systematic review
    Zhannat Nurgalieva
    Sections of Gastroenterology and Health Services Research, Houston Veterans Affairs Medical Center, and Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
    Dig Dis Sci 52:1345-54. 2007
    ..CK immunostaining distinguished well between BE and IM in noncardiac segments of the stomach; however, these comparisons are not clinically relevant...
  53. doi request reprint Prevalence of endoscopic findings of erosive esophagitis in children: a population-based study
    Mark A Gilger
    Department of Pediatrics, Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Veterans Administration Hospital, Houston, TX, USA
    J Pediatr Gastroenterol Nutr 47:141-6. 2008
    ..The prevalence of such GERD complications in children is unknown. The purpose of this study was to determine the prevalence of endoscopic findings of erosive esophagitis in children...
  54. ncbi request reprint Secular trends in the use, quality, and outcomes of gastrectomy for noncardia gastric cancer in the United States
    Anne Le
    Department of Surgery, Baylor College of Medicine and Michael E DeBakey VA Medical Center, Houston, Texas, USA
    Ann Surg Oncol 14:2519-27. 2007
    ..We examined the trends, extent, and determinants of surgical treatment and the influence of gastrectomy and adequacy of lymphadenectomy (defined as collection of 15 or more lymph nodes) on non-cardia gastric cancer survival...
  55. pmc Medications (NSAIDs, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with Barrett's esophagus
    Dang M Nguyen
    Section of Gastroenterology and Section of Health Services Research, Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas, USA
    Gastroenterology 138:2260-6. 2010
    ..However, the possible effect these medications may have on the risk of esophageal adenocarcinoma (EAC) in patients with existing Barrett's esophagus (BE) is unclear...
  56. ncbi request reprint Hepatocellular carcinoma: an epidemiologic view
    Hashem B El-Serag
    Section of Gastroenterology and Health Services Research at the Houston Department of Veterans Affairs Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    J Clin Gastroenterol 35:S72-8. 2002
    ..The future incidence trends of HCC will be determined to a large extent by the clinical course of HCV-infected people...
  57. ncbi request reprint The impact of immigration on the increasing incidence of hepatocellular carcinoma in the United States
    K Kulkarni
    Department of Medicine, Divisions of Gastroenterology, Houston, TX 77030, USA
    Aliment Pharmacol Ther 20:445-50. 2004
    ..To assess if the rising incidence of hepatocellular carcinoma in the United States can be accounted for by immigration and an ageing population, or is a true increase among the USA-born residents...
  58. pmc Statin therapy and serum transaminases among a cohort of HCV-infected veterans
    Louise M Henderson
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    Dig Dis Sci 55:190-5. 2010
    ..We sought to determine the effect of statin therapy on serum AST and ALT levels in a cohort of HCV-infected veterans with well-characterized liver disease...
  59. pmc Reducing referral delays in colorectal cancer diagnosis: is it about how you ask?
    Hardeep Singh
    VA Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Qual Saf Health Care 19:e27. 2010
    ..The authors tested whether certain details of information transmitted through computerised provider order entry (CPOE)-based referrals affected timeliness of diagnostic colonoscopy for patients with newly diagnosed CRC...
  60. doi request reprint Use of surveillance for hepatocellular carcinoma among patients with cirrhosis in the United States
    Jessica A Davila
    Section of Health Services Research, Houston Center for Quality of Care and Utilization Studies, Houston VA Medical Center and Baylor College of Medicine, Houston, TX, USA
    Hepatology 52:132-41. 2010
    ..5-fold and 2.8-fold, respectively, more likely to receive regular surveillance than those seen by a primary care physician only. Geographic variation in surveillance was observed and explained by patient and physician factors...
  61. doi request reprint Gastroesophageal reflux and asthma in children: a systematic review
    Kalpesh Thakkar
    Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine, 6621 Fannin St, CCC 1010, Houston, TX 77030, USA
    Pediatrics 125:e925-30. 2010
    ..The relationship between gastroesophageal reflux disease (GERD) and asthma in children has been investigated; however, the nature of the association (if any) between these 2 conditions is unclear...
  62. doi request reprint Utilization of surveillance for hepatocellular carcinoma among hepatitis C virus-infected veterans in the United States
    Jessica A Davila
    the Michael E DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas, USA
    Ann Intern Med 154:85-93. 2011
    ..Surveillance for hepatocellular carcinoma (HCC) is recommended for patients with hepatitis C virus (HCV) infection and cirrhosis. However, whether surveillance is being done as recommended is unknown...
  63. doi request reprint Surveillance for hepatocellular carcinoma: development and validation of an algorithm to classify tests in administrative and laboratory data
    Peter Richardson
    Section of Health Services Research, Houston Center for Quality of Care and Utilization Studies, The Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    Dig Dis Sci 55:3241-51. 2010
    ..The purpose of alpha-fetoprotein (AFP) and abdominal ultrasound (US) cannot be discerned in administrative data...
  64. pmc Missed opportunities to initiate endoscopic evaluation for colorectal cancer diagnosis
    Hardeep Singh
    Houston VA HSR and D Center of Excellence and The Center of Inquiry to Improve Outpatient Safety Through Effective Electronic Communication, Michael E DeBakey Veterans Affairs Medical Center and the Section of Health Services Research, Baylor College of Medicine, Houston, Texas, USA
    Am J Gastroenterol 104:2543-54. 2009
    ..Our objective was to describe missed opportunities to diagnose CRC before endoscopic referral, in terms of patient characteristics, nature of clinical clues, and types of diagnostic-process breakdowns involved...
  65. doi request reprint Human immunodeficiency virus-associated squamous cell cancer of the anus: epidemiology and outcomes in the highly active antiretroviral therapy era
    Elizabeth Y Chiao
    Department of Medicine, Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center 152, 2002 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 26:474-9. 2008
    ....
  66. ncbi request reprint Adapting the Rx-Risk-V for mortality prediction in outpatient populations
    Michael L Johnson
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    Med Care 44:793-7. 2006
    ..We sought to operationalize, test, and validate an outpatient pharmacy-based case-mix adjuster...
  67. pmc Is there a race-based disparity in the survival of veterans with HIV?
    Thomas P Giordano
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    J Gen Intern Med 21:613-7. 2006
    ..Disparities in survival for black patients with HIV in the United States have been reported. The VA is an equal access health care system...
  68. ncbi request reprint Risk factors of intrahepatic cholangiocarcinoma in the United States: a case-control study
    Yasser H Shaib
    Section of Health Services Research, Michael E DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 128:620-6. 2005
    ..In this case-control study, we used the Surveillance, Epidemiology, and End Results-Medicare database to evaluate the prevalence of known risk factors for intrahepatic cholangiocarcinoma and explore other potential risk factors...
  69. ncbi request reprint Utilization of screening for hepatocellular carcinoma in the United States
    Jessica A Davila
    Section of Health Services Research, Houston Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA
    J Clin Gastroenterol 41:777-82. 2007
    ..Screening for hepatocellular carcinoma (HCC) has been recommended for patients at high-risk of developing HCC. Yet, the utilization and determinants of screening remain unclear...
  70. ncbi request reprint Effect of human immunodeficiency virus and antiretrovirals on outcomes of hepatitis C: a systematic review from an epidemiologic perspective
    Jennifer R Kramer
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Clin Gastroenterol Hepatol 5:1321-1328.e7. 2007
    ..We systematically reviewed the literature examining the association of human immunodeficiency virus (HIV) and antiretroviral therapy (ART) with liver disease in patients with hepatitis C virus (HCV) infection...
  71. ncbi request reprint Racial disparities in utilization of liver transplantation for hepatocellular carcinoma in the United States, 1998-2002
    Abby B Siegel
    Department of Medicine, Mailman School of Public Health, Columbia University, New York, New York, USA
    Am J Gastroenterol 103:120-7. 2008
    ..We assessed recent predictors of use of liver transplantation and its effect on survival for those with nonmetastatic HCC...
  72. ncbi request reprint Hepatitis C coinfection increases the risk of fulminant hepatic failure in patients with HIV in the HAART era
    Jennifer R Kramer
    Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center 152, Houston, TX 77030, USA
    J Hepatol 42:309-14. 2005
    ..It is uncertain if patients coinfected with hepatitis C and HIV are more likely to suffer fulminant hepatic failure (FHF) when compared to patients with HIV-only...
  73. ncbi request reprint Cirrhosis and hepatocellular carcinoma in HIV-infected veterans with and without the hepatitis C virus: a cohort study, 1992-2001
    Thomas P Giordano
    Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Department of Veterans Affairs Medical Center, Houston, Tex 77030, USA
    Arch Intern Med 164:2349-54. 2004
    ....
  74. ncbi request reprint Genetic variants of glutathione S-transferase as possible risk factors for hepatocellular carcinoma: a HuGE systematic review and meta-analysis
    Donna L White
    The Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    Am J Epidemiol 167:377-89. 2008
    ..However, given the relatively limited total number of subjects examined and observed between-study heterogeneity, chance could not be excluded...
  75. ncbi request reprint Endoscopic and surgical therapy for intrahepatic cholangiocarcinoma in the united states: a population-based study
    Yasser H Shaib
    Sections of Health Services, Houston, TX, USA
    J Clin Gastroenterol 41:911-7. 2007
    ..Intrahepatic cholangiocarcinoma (ICC) is a highly fatal disease with limited therapeutic options. The determinants, trends, and outcomes of different therapies for ICC are largely unknown in the United States...
  76. ncbi request reprint Psychiatric disorders among veterans with hepatitis C infection
    Hashem B El-Serag
    Section of Gastroenterology, The Houston Center for Quality Care and Utilization Studies, The Houston Veterans Affairs Medical Center and the Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
    Gastroenterology 123:476-82. 2002
    ..The presence of psychiatric, drug-, and alcohol-use disorders in hepatitis C virus (HCV)-infected patients may influence their management and prognosis. The frequency and the risk for these disorders among HCV-infected patients are unknown...
  77. ncbi request reprint National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs
    Neena S Abraham
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Texas 77030, USA
    Gastroenterology 129:1171-8. 2005
    ..Our objective was to assess adherence to evidence-based guidelines by providers of the Department of Veterans Affairs nationwide...
  78. ncbi request reprint Oral contraception and the risk of hepatocellular carcinoma
    Shail Maheshwari
    Sections of Gastroenterology and Health Services Research at the Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, 2002 Holcombe Blvd, Houston, TX 77030, USA
    J Hepatol 47:506-13. 2007
    ..We performed a meta-analysis of observational epidemiological studies to examine the association between oral contraceptives (OC) and hepatocellular carcinoma (HCC)...
  79. pmc The epidemiology of obesity
    Dang M Nguyen
    Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX 77030, USA
    Gastroenterol Clin North Am 39:1-7. 2010
    ..This article describes some of the epidemiologic features of obesity, including global prevalence, secular trends, risk factors, and burden of illness related to obesity with special emphasis on obesity trends in the United States...
  80. pmc Medication usage and the risk of neoplasia in patients with Barrett's esophagus
    Dang M Nguyen
    Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    Clin Gastroenterol Hepatol 7:1299-304. 2009
    ..However, only limited data are available on chemoprevention in patients with BE...
  81. doi request reprint Epidemiology of non-erosive reflux disease
    Hashem B El-Serag
    Department of Medicine, Baylor College of Medicine and The Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Department of Veterans Affairs Medical Center, Houston, Tex 77030, USA
    Digestion 78:6-10. 2008
    ..The temporal trends in NERD are unclear, and are probably increasing because GERD symptom prevalence has increased...
  82. pmc Hepatitis C infection and risk of diabetes: a systematic review and meta-analysis
    Donna L White
    Section of Gastroenterology and Hepatology, Baylor College of Medicine, Michael E DeBakey VA Medical Center, Houston, TX 77030, USA
    J Hepatol 49:831-44. 2008
    ..We performed meta-analyses to examine whether HCV infection does increase DM risk in comparison to the general population and in other sub-groups with increased liver disease rates including with hepatitis B (HBV)...
  83. ncbi request reprint The impact of curative intent surgery on the survival of pancreatic cancer patients: a U.S. Population-based study
    Yasser Shaib
    Division of Gastroenterology, Michael E DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA
    Am J Gastroenterol 102:1377-82. 2007
    ..Curative intent surgery (CIS) is presumed to be the only curative option in the treatment of pancreatic cancer. The determinants and the outcomes of surgical resection are not clear at the population level...
  84. ncbi request reprint Risk of non-Hodgkin lymphoma and lymphoproliferative precursor diseases in US veterans with hepatitis C virus
    Thomas P Giordano
    Department of Medicine, Baylor College of Medicine, and The Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey Veterans Affairs Medical Center, Houston, Tex 77030, USA
    JAMA 297:2010-7. 2007
    ..Previous studies have been too small to adequately assess these risks...
  85. ncbi request reprint Racial disparities and socioeconomic status in association with survival in a large population-based cohort of elderly patients with colon cancer
    Xianglin L Du
    Division of Epidemiology, School of Public Health, The University of Texas Health Science Center, Houston, Texas, USA
    Cancer 110:660-9. 2007
    ..To the authors' knowledge, few studies have addressed racial disparities in the survival of patients with colon cancer by adequately incorporating treatment and socioeconomic factors in addition to patient and tumor characteristics...
  86. ncbi request reprint Burden of liver disease in the United States: summary of a workshop
    W Ray Kim
    Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Hepatology 36:227-42. 2002
  87. ncbi request reprint Hepatitis C infection: dying with or from the infection?
    Hashem El-Serag
    J Hepatol 48:183-4. 2008

Research Grants10

  1. Gene Expression in Barrett's Esophagus
    Hashem El Serag; Fiscal Year: 2006
    ..We present preliminary data on microarray and RT-PCRanalyses on 5 patients with BE that suggest an overactive Wnt pathway: we have also assembled the essential components of a successful study using microarrays. ..
  2. Surveillance for Hepatocellular Carcinoma among HCV-infected Veterans
    Hashem El Serag; Fiscal Year: 2009
    ..Evaluating the extent and patterns of HCC surveillance is crucial in understanding diffusion (and obstacles) of this practice and in designing interventions to improve the implementation of HCC surveillance. ..
  3. Obesity, H pylori and Risk of Barrett's Esophagus
    Hashem El Serag; Fiscal Year: 2009
    ..Subsequently, in a case-control study, all newly diagnosed BE and randomly selected controls will be examined for the volume and activity of visceral obesity (CT scan and serum adipocytokines). ..
  4. Surveillance for Hepatocellular Carcinoma among HCV-infected Veterans
    Hashem El Serag; Fiscal Year: 2007
    ..Evaluating the extent and patterns of HCC surveillance is crucial in understanding diffusion (and obstacles) of this practice and in designing interventions to improve the implementation of HCC surveillance. ..
  5. Epidemiology and Outcomes of Digestive and Liver Diseases: A Mentoring Program
    Hashem El Serag; Fiscal Year: 2007
    ..pylori infection on BE tissue COX-2 expression. ..
  6. Obesity, H pylori and Risk of Barrett's Esophagus
    Hashem El Serag; Fiscal Year: 2007
    ..Subsequently, in a case-control study, all newly diagnosed BE and randomly selected controls will be examined for the volume and activity of visceral obesity (CT scan and serum adipocytokines). ..
  7. Obesity, H pylori and Risk of Barrett's Esophagus
    Hashem B El Serag; Fiscal Year: 2010
    ..Subsequently, in a case-control study, all newly diagnosed BE and randomly selected controls will be examined for the volume and activity of visceral obesity (CT scan and serum adipocytokines). ..