D M Dougherty

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Possible amotivational effects following marijuana smoking under laboratory conditions
    Don R Cherek
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston, Health Science Center, 77030, USA
    Exp Clin Psychopharmacol 10:26-38. 2002
  2. ncbi request reprint Commission error rates on a continuous performance test are related to deficits measured by the Benton Visual Retention Test
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 77030, USA
    Assessment 10:3-12. 2003
  3. ncbi request reprint Familial transmission of Continuous Performance Test behavior: attentional and impulsive response characteristics
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030, USA
    J Gen Psychol 130:5-21. 2003
  4. ncbi request reprint Age at first drink relates to behavioral measures of impulsivity: the immediate and delayed memory tasks
    Donald M Dougherty
    University of Texas Health Science Center at Houston, Neurobehavioral Research Laboratory and Clinic, Houston, Texas 77030, USA
    Alcohol Clin Exp Res 28:408-14. 2004
  5. ncbi request reprint Immediate and delayed memory tasks: a computerized behavioral measure of memory, attention, and impulsivity
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund Street, Houston, TX 77030, USA
    Behav Res Methods Instrum Comput 34:391-8. 2002
  6. ncbi request reprint Behavioral impulsivity paradigms: a comparison in hospitalized adolescents with disruptive behavior disorders
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030 3406, USA
    J Child Psychol Psychiatry 44:1145-57. 2003
  7. ncbi request reprint Effects of moderate and high doses of alcohol on attention, impulsivity, discriminability, and response bias in immediate and delayed memory task performance
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center 77030, USA
    Alcohol Clin Exp Res 24:1702-11. 2000
  8. ncbi request reprint Laboratory measures of aggression and impulsivity in women with borderline personality disorder
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, Harris County Psychiatric Center, University of Texas, Houston 77030, USA
    Psychiatry Res 85:315-26. 1999
  9. ncbi request reprint Immediate versus delayed visual memory task performance among schizophrenic patients and normal control subjects
    D M Dougherty
    Harris County Psychiatric Center, Department of Psychiatry and Behavioral Sciences, University of Texas at Houston Health Science Center, 77030, USA
    Psychiatry Res 79:255-65. 1998
  10. ncbi request reprint Influence of trait hostility on tryptophan depletion-induced laboratory aggression
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, 77030, USA
    Psychiatry Res 88:227-32. 1999

Detail Information

Publications47

  1. ncbi request reprint Possible amotivational effects following marijuana smoking under laboratory conditions
    Don R Cherek
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston, Health Science Center, 77030, USA
    Exp Clin Psychopharmacol 10:26-38. 2002
    ..Increasing the monetary value of the reinforcer diminished the acute marijuana effects on PR responding, suggesting that marijuana exerted an effect primarily on reinforcers of a smaller magnitude...
  2. ncbi request reprint Commission error rates on a continuous performance test are related to deficits measured by the Benton Visual Retention Test
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 77030, USA
    Assessment 10:3-12. 2003
    ..These results may be explained by a shared association between processes of impulsivity and other deficits of executive control that may interfere with successful performance of the Benton...
  3. ncbi request reprint Familial transmission of Continuous Performance Test behavior: attentional and impulsive response characteristics
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030, USA
    J Gen Psychol 130:5-21. 2003
    ..e., BIS) was correlated with commission errors for parents, but not for adolescents. The findings of this study support the use of an objective behavioral measure of impulsivity to assess familial relationships of impulsivity...
  4. ncbi request reprint Age at first drink relates to behavioral measures of impulsivity: the immediate and delayed memory tasks
    Donald M Dougherty
    University of Texas Health Science Center at Houston, Neurobehavioral Research Laboratory and Clinic, Houston, Texas 77030, USA
    Alcohol Clin Exp Res 28:408-14. 2004
    ..This study examined the relationship between laboratory-measured impulsivity and age at first drink...
  5. ncbi request reprint Immediate and delayed memory tasks: a computerized behavioral measure of memory, attention, and impulsivity
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund Street, Houston, TX 77030, USA
    Behav Res Methods Instrum Comput 34:391-8. 2002
    ..Preliminary studies have demonstrated that these laboratory tasks are sensitive to group differences, produce stable baselines of performance, and are sensitive to drug-induced performance decrements...
  6. ncbi request reprint Behavioral impulsivity paradigms: a comparison in hospitalized adolescents with disruptive behavior disorders
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77030 3406, USA
    J Child Psychol Psychiatry 44:1145-57. 2003
    ..As a result, comparisons between measures are difficult, with little consensus regarding which method may be most sensitive to individual impulsivity differences of different populations...
  7. ncbi request reprint Effects of moderate and high doses of alcohol on attention, impulsivity, discriminability, and response bias in immediate and delayed memory task performance
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center 77030, USA
    Alcohol Clin Exp Res 24:1702-11. 2000
    ..The first is important because previous studies have shown little effect of alcohol on attention, and the second is important because commission errors have been related to impulsive behaviors...
  8. ncbi request reprint Laboratory measures of aggression and impulsivity in women with borderline personality disorder
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, Harris County Psychiatric Center, University of Texas, Houston 77030, USA
    Psychiatry Res 85:315-26. 1999
    ..Aggressive responding rates correlated positively with BDHI scores. These results extend previous findings that negative affect in women is reflected in laboratory behavioral measures...
  9. ncbi request reprint Immediate versus delayed visual memory task performance among schizophrenic patients and normal control subjects
    D M Dougherty
    Harris County Psychiatric Center, Department of Psychiatry and Behavioral Sciences, University of Texas at Houston Health Science Center, 77030, USA
    Psychiatry Res 79:255-65. 1998
    ..This paradigm may prove useful in discriminating subtle differences in immediate and delayed memory capability among psychiatric populations and normal control subjects...
  10. ncbi request reprint Influence of trait hostility on tryptophan depletion-induced laboratory aggression
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, 77030, USA
    Psychiatry Res 88:227-32. 1999
    ..These preliminary data support earlier findings that compared to non-hostile men, hostile men may be more prone to behavior change induced by the perturbation of the 5-HT neurotransmitter system...
  11. ncbi request reprint Endogenous plasma testosterone levels and commission errors in women: A preliminary report
    J M Bjork
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas-Houston Medical School, 1300 Moursund, Houston, TX 77030, USA
    Physiol Behav 73:217-21. 2001
    ..In light of the fact previous studies find commission errors on the CPT are associated with impulsivity, the results of this study support a positive relationship between testosterone and impulsivity...
  12. ncbi request reprint Alcohol increases commission error rates for a continuous performance test
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center 77030, USA
    Alcohol Clin Exp Res 23:1342-51. 1999
    ..e., (1) perhaps because of the ease of the task used in previous experiments, alcohol has not been found to impair performance, and (2) CPT commission errors (described below) have been related to impulsive behavior...
  13. ncbi request reprint Laboratory measurement of adaptive behavior change in humans with a history of substance dependence
    S D Lane
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston 77030, USA
    Drug Alcohol Depend 51:239-52. 1998
    ..These data suggest a deficiency in adaptive behavior change, particularly when that change requires an abrupt slowing of response rates following a brief history of high-rate responding...
  14. ncbi request reprint Ipsapirone neuroendocrine challenge: relationship to aggression as measured in the human laboratory
    F G Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, 77030, USA
    Psychiatry Res 81:31-8. 1998
    ..This study supports a relationship between serotonin function and aggression as measured in the human laboratory, similar to the well-documented association between self-reported aggression and serotonin...
  15. ncbi request reprint Measurement of inter-episode impulsivity in bipolar disorder
    A C Swann
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, 77030, USA
    Psychiatry Res 101:195-7. 2001
    ..Laboratory measurements of impulsivity correlated with a BIS-11 score or severity of manic symptoms. Impulsivity in bipolar disorder may have both stable and state-dependent aspects...
  16. ncbi request reprint The influence of menstrual-cycle phase on the relationship between testosterone and aggression
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, The University of Texas, Houston 77030, USA
    Physiol Behav 62:431-5. 1997
    ..self-report of perimenstrual symptomatology is a more consistent predictor of aggressive behavior across the menstrual cycle than plasma testosterone; and 3. perimenstrual emotional symptomatology is not related to testosterone levels...
  17. ncbi request reprint Psychiatric aspects of impulsivity
    F G Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, 77030, USA
    Am J Psychiatry 158:1783-93. 2001
    ..The authors discuss the relationship of impulsivity to psychiatric disorders and present selected hypotheses regarding the reasons for these relationships...
  18. ncbi request reprint Plasma L-tryptophan depletion and aggression
    D M Dougherty
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School 77030, USA
    Adv Exp Med Biol 467:57-65. 1999
    ..Extending these studies to women appears to be the much-needed next step given that serotonergic levels appear to vary both as a function of the menstrual cycle phase and menstrual symptomatology...
  19. ncbi request reprint Low dose zolmitriptan as a 5-HT neuroendocrine challenge agent in humans
    F G Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, Houston 77030, USA
    Psychoneuroendocrinology 25:607-18. 2000
    ..The neuroendocrine effects of 2.5 mg of orally administered zolmitriptan are similar to previously reported effects of sumatriptan, with minimal side effects...
  20. ncbi request reprint The impact of impulsivity on cocaine use and retention in treatment
    F G Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Houston Health Science Center, Houston, TX 77030, USA
    J Subst Abuse Treat 21:193-8. 2001
    ..This study shows that impulsivity is a significant predictor of cocaine use and treatment retention, and suggests the need for targeting impulsivity in cocaine dependence treatment...
  21. ncbi request reprint Antisocial personality disorder, alcohol, and aggression
    F G Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas-Houston, USA
    Alcohol Res Health 25:5-11. 2001
    ..Alternatively, the association between ASPD and alcohol-related aggression may stem from some as yet undetermined factor(s) that increase the risk for aggression in general...
  22. ncbi request reprint Laboratory measured behavioral impulsivity relates to suicide attempt history
    Donald M Dougherty
    Neuro behavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
    Suicide Life Threat Behav 34:374-85. 2004
    ..This study helps to demonstrate how laboratory behavioral measures of impulsivity can be used to discriminate groups based on suicidal histories among samples not currently exhibiting significant suicidal behaviors...
  23. ncbi request reprint Acute yohimbine increases laboratory-measured impulsivity in normal subjects
    Alan C Swann
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, Texas 77030, USA
    Biol Psychiatry 57:1209-11. 2005
    ....
  24. ncbi request reprint Reduced anterior corpus callosum white matter integrity is related to increased impulsivity and reduced discriminability in cocaine-dependent subjects: diffusion tensor imaging
    Frederick Gerard Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Neuropsychopharmacology 30:610-7. 2005
    ....
  25. ncbi request reprint Laboratory behavioral measures of impulsivity
    Donald M Dougherty
    Department of Psychiatry and Behavioral Medicine, School of Medicine, Wake Forest University Health Sciences, Medical Center Blvd, Winston Salem, NC 27157, USA
    Behav Res Methods 37:82-90. 2005
    ..The four paradigms in this software package are available at no cost and can be obtained by contacting the corresponding author...
  26. ncbi request reprint Increased impulsivity associated with severity of suicide attempt history in patients with bipolar disorder
    Alan C Swann
    Department of Psychiatry, University of Texas Medical School at Houston, 1300 Moursund, Rm 270, Houston, TX 77030, USA
    Am J Psychiatry 162:1680-7. 2005
    ..The purpose of this study was to investigate the relationship between impulsivity and severity of past suicidal behavior, a potential predictor of eventual suicide, in patients with bipolar disorder...
  27. ncbi request reprint The effects of alcohol on laboratory-measured impulsivity after L: -Tryptophan depletion or loading
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Psychopharmacology (Berl) 193:137-50. 2007
    ....
  28. pmc Characterizing aggressive behavior with the Impulsive/Premeditated Aggression Scale among adolescents with conduct disorder
    Charles W Mathias
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Psychiatry Res 151:231-42. 2007
    ..As in the adult and child literature, characterization of aggressive behavior into two subtypes appears to be relevant to understanding individual differences among adolescents with Conduct Disorder...
  29. pmc Manic symptoms and impulsivity during bipolar depressive episodes
    Alan C Swann
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, TX 77030, USA
    Bipolar Disord 9:206-12. 2007
    ..Therefore, we investigated the prevalence of manic symptoms and their relationships to impulsivity and clinical characteristics in patients with bipolar depressive episodes...
  30. ncbi request reprint Impulsive and premeditated subtypes of aggression in conduct disorder: differences in time estimation
    Donald M Dougherty
    Department of Psychiatry and Behavioral Medicine, Neurobehavioral Research Laboratory and Clinic, Wake Forest University School of Medicine Winston Salem, North Carolina 27157, USA
    Aggress Behav 33:574-82. 2007
    ..This study confirms the importance of considering the role and type of physical aggression when studying heterogeneous diagnostic groups like CD and supports the relevance of time estimation to certain subgroups of adolescents with CD...
  31. pmc A test of alcohol dose effects on multiple behavioral measures of impulsivity
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Drug Alcohol Depend 96:111-20. 2008
    ..Acute alcohol administration affects impulsive behavior, although these effects vary as a function of alcohol dose, assessment instrument, and time of measurement following administration...
  32. ncbi request reprint Suicidal behaviors and drug abuse: impulsivity and its assessment
    Donald M Dougherty
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 1300 Moursund Street, Houston, TX 77030, USA
    Drug Alcohol Depend 76:S93-S105. 2004
    ..To better account for influence of impulsivity in these psychiatric disturbances, no single source of measurement should be used without the consideration of other types of instruments...
  33. ncbi request reprint Serotonin 2a receptor T102C polymorphism and impaired impulse control
    James M Bjork
    Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry and Behavioral Sciences, University of Texas Houston Medical School, Houston, Texas 77030, USA
    Am J Med Genet 114:336-9. 2002
    ..These preliminary data suggest that the T102C 5-HT2a receptor polymorphism may be a marker for impaired behavior control-perhaps in the context of psychiatric disorder history...
  34. ncbi request reprint Laboratory-measured aggressive behavior of women: acute tryptophan depletion and augmentation
    Dawn M Marsh
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund Street, Houston, TX 77030, USA
    Neuropsychopharmacology 26:660-71. 2002
    ..These findings indicate that both T+ and T- can influence aggressive behavior and that certain subgroups of women may be more susceptible to serotonin manipulation...
  35. ncbi request reprint Increased impulsivity in cocaine dependent subjects independent of antisocial personality disorder and aggression
    F Gerard Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, 1300 Moursund, Houston, TX 77030, USA
    Drug Alcohol Depend 68:105-11. 2002
    ..This study supports the hypothesis that the increased impulsivity as measured by the BIS-11 in cocaine dependent individuals is not exclusively due to concomitant increases in aggression or ASPD...
  36. ncbi request reprint Reliability estimates for the immediate and delayed memory tasks
    Charles W Mathias
    Neurobehavioral Research Laboratory and Clinic, University of Texas Health Science Center at Houston, 77030, USA
    Percept Mot Skills 95:559-69. 2002
    ..Analyses indicated that the primary variable of interest, i.e., commission of errors, showed acceptable reliability within and across testing periods...
  37. ncbi request reprint Impulsivity and phase of illness in bipolar disorder
    Alan C Swann
    Department of Psychiatry, University of Texas Mental Sciences Institute, University of Texas Health Science Center, Houston, TX, USA
    J Affect Disord 73:105-11. 2003
    ..Impulsivity is prominent in bipolar disorder, but there is little quantitative information relating it to phase of illness...
  38. ncbi request reprint Two models of impulsivity: relationship to personality traits and psychopathology
    Alan C Swann
    Department of Psychiatry, University of Texas Medical School, Houston, Texas, USA
    Biol Psychiatry 51:988-94. 2002
    ....
  39. ncbi request reprint Impulsivity: a link between bipolar disorder and substance abuse
    Alan C Swann
    Department of Psychiatry and Behavioral Sciences, Mental Sciences Institute, Harris County Psychiatric Hospital, University of Texas Health Science Center, Houston, 77030, USA
    Bipolar Disord 6:204-12. 2004
    ..Substance abuse is present in most patients with bipolar disorder and associated with poor treatment outcome and increased risk of suicide. Increased impulsivity may be a link between bipolar disorder and substance abuse...
  40. ncbi request reprint Functional MRI study of working memory in MDMA users
    F Gerard Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, 1300 Moursund, Houston, TX 77030, USA
    Psychopharmacology (Berl) 177:185-94. 2004
    ..Similarly, behavioral studies in human MDMA users regularly find abnormalities in memory, mood, and impulse control. However, studies of brain function using brain imaging in MDMA users have been less consistent...
  41. ncbi request reprint P300 event-related potential amplitude and impulsivity in cocaine-dependent subjects
    F Gerard Moeller
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center Houston, Moursund, Houston, Texas, USA
    Neuropsychobiology 50:167-73. 2004
    ..This study supports the hypothesis that the basic neurophysiology responsible for the P300 amplitude in cocaine-dependent individuals is associated with impulsivity independent of a history of childhood conduct disorder symptoms...
  42. ncbi request reprint Impulsivity and BOLD fMRI activation in MDMA users and healthy control subjects
    Ignacio H Valdes
    Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund, Houston, TX 77030, USA
    Psychiatry Res 147:239-42. 2006
    ..A significant correlation between BIS scores and DLPFC activation was found, supporting a role for the DLPFC in BIS-measured impulsivity...
  43. ncbi request reprint The biphasic effects of alcohol: comparisons of subjective and objective measures of stimulation, sedation, and physical activity
    Merideth A Addicott
    Department of Radiology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Alcohol Clin Exp Res 31:1883-90. 2007
    ..However, little is known about the effects of alcohol on physical activity or the relationship between physical activity and subjective self-report measures of stimulation and sedation following alcohol consumption in humans...
  44. ncbi request reprint Personality judgment and personality pathology: self-other agreement in adolescents with conduct disorder
    R Michael Furr
    Department of Psychology, Wake Forest University, NC 27106, USA
    J Pers 75:629-62. 2007
    ..Results have implications for understanding the processes affecting personality judgment, for increasing integration of traditional personality research and personality pathology, and for personality assessment...
  45. pmc Teenagers do not always lie: characteristics and correspondence of telephone and in-person reports of adolescent drug use
    Erin E Shannon
    Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston Salem, NC, United States
    Drug Alcohol Depend 90:288-91. 2007
    ..Additionally, parents appear to become more aware of their adolescent's drug use with increased frequency of use...
  46. ncbi request reprint Cannabis withdrawal among adolescent cannabis users in an outpatient research setting
    Michael A Dawes
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am J Addict 15:485-6. 2006
  47. ncbi request reprint Overview of workshop on drug abuse and suicidal behavior
    Lynda Erinoff
    Drug Alcohol Depend 76:S3-9. 2004