B A Cotton

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc Cosyntropin as a diagnostic agent in the screening of patients for adrenocortical insufficiency
    David D Hamilton
    Department of Surgery, The University of Texas Health Science Center, Houston, TX, USA
    Clin Pharmacol 2:77-82. 2010
  2. pmc Treatments for reversing warfarin anticoagulation in patients with acute intracranial hemorrhage: a structured literature review
    Brett F Bechtel
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Int J Emerg Med 4:40. 2011
  3. doi request reprint Hyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administration
    Bryan A Cotton
    Department of Surgery, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 73:365-70; discussion 370. 2012
  4. doi request reprint Admission rapid thrombelastography predicts development of pulmonary embolism in trauma patients
    Bryan A Cotton
    Department of Surgery, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 72:1470-5; discussion 1475-7. 2012
  5. pmc FIBTEM provides early prediction of massive transfusion in trauma
    Herbert Schöchl
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and AUVA Research Centre, Donaueschingenstraße 13, A 1200 Vienna, Austria
    Crit Care 15:R265. 2011
  6. pmc All bleeding stops: how we can help
    William P Riordan
    Vanderbilt University Medical Center, 1211 21stAvenue South, 404 Medical Arts Building, Nashville, TN 37212, USA
    Crit Care 14:146. 2010
  7. ncbi request reprint Acutely injured patients on dabigatran
    Bryan A Cotton
    Center for Translational Injury Research, Houston, TX
    N Engl J Med 365:2039-40. 2011
  8. doi request reprint Multicenter validation of a simplified score to predict massive transfusion in trauma
    Bryan A Cotton
    Department of Surgery and the Center for Translational Injury Research, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 69:S33-9. 2010
  9. doi request reprint Room for (performance) improvement: provider-related factors associated with poor outcomes in massive transfusion
    Bryan A Cotton
    Department of Surgery, Center for Translational Injury Research, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 67:1004-12. 2009
  10. doi request reprint Guidelines for prehospital fluid resuscitation in the injured patient
    Bryan A Cotton
    Department of Surgery, University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 67:389-402. 2009

Collaborators

Detail Information

Publications39

  1. pmc Cosyntropin as a diagnostic agent in the screening of patients for adrenocortical insufficiency
    David D Hamilton
    Department of Surgery, The University of Texas Health Science Center, Houston, TX, USA
    Clin Pharmacol 2:77-82. 2010
    ..While steroids have a place in the ICU, specific dosing and length of administration remain inconsistent...
  2. pmc Treatments for reversing warfarin anticoagulation in patients with acute intracranial hemorrhage: a structured literature review
    Brett F Bechtel
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Int J Emerg Med 4:40. 2011
    ..abstract:..
  3. doi request reprint Hyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administration
    Bryan A Cotton
    Department of Surgery, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 73:365-70; discussion 370. 2012
    ..To further strengthen this hypothesis, we created an in vitro hemodilution model to improve our mechanistic understanding of the early HF...
  4. doi request reprint Admission rapid thrombelastography predicts development of pulmonary embolism in trauma patients
    Bryan A Cotton
    Department of Surgery, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma Acute Care Surg 72:1470-5; discussion 1475-7. 2012
    ..The purpose of this study was to identify whether admission rapid-thrombelastography (r-TEG) could identify patients at risk of developing pulmonary embolism (PE) during their hospital stay...
  5. pmc FIBTEM provides early prediction of massive transfusion in trauma
    Herbert Schöchl
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and AUVA Research Centre, Donaueschingenstraße 13, A 1200 Vienna, Austria
    Crit Care 15:R265. 2011
    ..Whole-blood thromboelastometry (ROTEM®) tests provide immediate information about the coagulation status of acute bleeding trauma patients. We investigated their value for early prediction of MT...
  6. pmc All bleeding stops: how we can help
    William P Riordan
    Vanderbilt University Medical Center, 1211 21stAvenue South, 404 Medical Arts Building, Nashville, TN 37212, USA
    Crit Care 14:146. 2010
    ..Many of the recommendations are appropriately broad enough to promote the use of clinical judgment in the application of the guidelines...
  7. ncbi request reprint Acutely injured patients on dabigatran
    Bryan A Cotton
    Center for Translational Injury Research, Houston, TX
    N Engl J Med 365:2039-40. 2011
    ..The new oral direct thrombin inhibitor, dabigatran, is proving to be problematic in acutely injured patients, since it may promote bleeding and its effect cannot be easily reversed...
  8. doi request reprint Multicenter validation of a simplified score to predict massive transfusion in trauma
    Bryan A Cotton
    Department of Surgery and the Center for Translational Injury Research, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 69:S33-9. 2010
    ..Early identification of lethal exsanguination may improve survival in this patient population. The purpose of the current study was to validate a simplified score to predict MT at multiple Level I trauma centers...
  9. doi request reprint Room for (performance) improvement: provider-related factors associated with poor outcomes in massive transfusion
    Bryan A Cotton
    Department of Surgery, Center for Translational Injury Research, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 67:1004-12. 2009
    ..The purpose of this study was to identify the incidence and impact of MT protocol noncompliance and to intervene in provider-related events associated with poor compliance and outcomes...
  10. doi request reprint Guidelines for prehospital fluid resuscitation in the injured patient
    Bryan A Cotton
    Department of Surgery, University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 67:389-402. 2009
    ..for access? (3) if access is achieved, should intravenous fluids be administered? (4) if fluids are to be administered, which solution is preferred? and (5) if fluids are to be administered, what volume and rate should be infused?..
  11. pmc Damage control resuscitation is associated with a reduction in resuscitation volumes and improvement in survival in 390 damage control laparotomy patients
    Bryan A Cotton
    Department of Surgery, The University of Texas Health Science Center, Houston, TX, USA
    Ann Surg 254:598-605. 2011
    ..To determine whether implementation of damage control resuscitation (DCR) in patients undergoing damage control laparotomy (DCL) translates into improved survival...
  12. ncbi request reprint Cost-utility analysis of levetiracetam and phenytoin for posttraumatic seizure prophylaxis
    Bryan A Cotton
    Department of Surgery and the Center for Translational Injury Research, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 71:375-9. 2011
    ..The purpose of this study was to evaluate whether phenytoin or levetiracetam would be more cost-effective in preventing early post-TBI seizures and reducing their negative impact on TBI outcomes...
  13. ncbi request reprint Rapid thrombelastography delivers real-time results that predict transfusion within 1 hour of admission
    Bryan A Cotton
    Department of Surgery, The University of Texas Health Science Center, Houston, Texas 77030, USA
    J Trauma 71:407-14; discussion 414-7. 2011
    ..The purpose of this pilot study was to evaluate the timeliness of r-TEG results, their correlation with CCTs, and the ability of r-TEG to predict early blood transfusion...
  14. doi request reprint Specific abbreviated injury scale values are responsible for the underestimation of mortality in penetrating trauma patients by the injury severity score
    Susan E Rowell
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 97227, USA
    J Trauma 71:S384-8. 2011
    ..We hypothesized that the mechanism-based difference in mortality could be attributed to certain ISS ranges and specific AIS values by body region...
  15. doi request reprint Variations between level I trauma centers in 24-hour mortality in severely injured patients requiring a massive transfusion
    Charles E Wade
    Department of Surgery, and The Center for Translational Injury Research, The University of Texas Health Science Center at Houston, Houston, Texas, USA
    J Trauma 71:S389-93. 2011
    ..We hypothesized differences among centers in 24-hour mortality could predominantly be accounted for by differences in transfusion practices as well as patient characteristics...
  16. doi request reprint Gender-based differences in mortality in response to high product ratio massive transfusion
    Susan E Rowell
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 71:S375-9. 2011
    ..This has not been examined independently in women and men. A gender dichotomy in outcome after severe injury is known to exist. This study examined gender-related differences in mortality after high product ratio massive transfusion...
  17. doi request reprint A high fresh frozen plasma: packed red blood cell transfusion ratio decreases mortality in all massively transfused trauma patients regardless of admission international normalized ratio
    Lisa M Brown
    Department of Surgery, University of California, San Francisco, San Francisco, California 94143 0470, USA
    J Trauma 71:S358-63. 2011
    ..Therefore, we hypothesized that patients with elevated International Normalized Ratio (INR) on arrival to the hospital may benefit more from transfusion with a high ratio of FFP:PRBC than those with a lower INR...
  18. doi request reprint Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients
    Susan E Rowell
    Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 71:S353-7. 2011
    ..This study was performed to determine whether mortality after high product ratio massive transfusion is different in blunt and penetrating trauma patients...
  19. doi request reprint Increased platelet:RBC ratios are associated with improved survival after massive transfusion
    John B Holcomb
    Division of Acute Care Surgery, Center for Translational Injury Research, University of Texas Health Sciences Center, Houston, Texas 77030, USA
    J Trauma 71:S318-28. 2011
    ..However, outcomes associated with platelet transfusions are poorly characterized. We hypothesized that increased platelet:red blood cells (RBC) ratios would decrease hemorrhagic death and improve survival after massive transfusion (MT)...
  20. doi request reprint High ratios of plasma and platelets to packed red blood cells do not affect mortality in nonmassively transfused patients
    Chitra N Sambasivan
    Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Trauma 71:S329-36. 2011
    ..We aimed to determine the effect of high ratios of fresh frozen plasma (FFP) and platelets (PLT) to packed red blood cells (PRBC) in nonmassively transfused patients...
  21. doi request reprint A normal platelet count may not be enough: the impact of admission platelet count on mortality and transfusion in severely injured trauma patients
    Lisa M Brown
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 71:S337-42. 2011
    ..The purpose of this study was to examine the relationship between admission platelet count and outcomes after trauma...
  22. doi request reprint Early prediction of massive transfusion in trauma: simple as ABC (assessment of blood consumption)?
    Timothy C Nunez
    Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Trauma 66:346-52. 2009
    ..The purpose of this study was to validate previously described MT scoring systems and compare these to a simplified nonlaboratory dependent scoring system (Assessment of Blood Consumption [ABC] score)...
  23. doi request reprint Predefined massive transfusion protocols are associated with a reduction in organ failure and postinjury complications
    Bryan A Cotton
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    J Trauma 66:41-8; discussion 48-9. 2009
    ..The purpose of this study was to determine whether MT protocols are associated with increased organ failure and complications...
  24. doi request reprint Pentobarbital coma for refractory intra-cranial hypertension after severe traumatic brain injury: mortality predictions and one-year outcomes in 55 patients
    Gary T Marshall
    Department of Surgery, Division of Trauma and General Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Trauma 69:275-83. 2010
    ..This is a retrospective cohort study of severe TBI patients receiving PBC at Level I Trauma Center and tertiary university hospital...
  25. doi request reprint Challenges to effective research in acute trauma resuscitation: consent and endpoints
    John B Holcomb
    Center for Translational Injury Research, University of Texas Health Science Center at Houston, 6410 Fannin St, Houston, TX, USA
    Shock 35:107-13. 2011
    ..The consensus was that more discussion was needed and that consideration of new endpoints for clinical trials in emergency trauma research was a worthwhile and necessary goal...
  26. doi request reprint Exsanguination protocol improves survival after major hepatic trauma
    Victor Zaydfudim
    Department of Surgery, Vanderbilt University Medical Center, D 4314 Medical Center North, Nashville, TN 37232 2730, USA
    Injury 41:30-4. 2010
    ..We hypothesised that utilisation of our institution's TEP at the initiation of hospital resuscitation would improve survival in patients with significant hepatic trauma...
  27. pmc Creation, implementation, and maturation of a massive transfusion protocol for the exsanguinating trauma patient
    Timothy C Nunez
    Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, Texas, USA
    J Trauma 68:1498-505. 2010
    ..Once implemented, this process may lead to improved clinical outcomes and decreased overall blood utilization with extremely small wastage of vital blood products...
  28. doi request reprint Emergency department blood transfusion predicts early massive transfusion and early blood component requirement
    Timothy C Nunez
    Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, Texas, USA
    Transfusion 50:1914-20. 2010
    ..The purpose of this study was to evaluate the ability of uncrossmatched transfusions in the emergency department (ED) to predict early (< 6 hr) massive transfusion (MT) of red blood cells (RBCs) and blood components...
  29. doi request reprint Use of scene vital signs improves TRISS predicted survival in intubated trauma patients
    Igor V Voskresensky
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37212, USA
    J Surg Res 154:105-11. 2009
    ..The purpose of this study was to assess the impact of scene vital signs on predicting survival in intubated trauma patients...
  30. ncbi request reprint Acute adrenal insufficiency may affect outcome in the trauma patient
    Oscar D Guillamondegui
    Department of Surgery, Division of Trauma, Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA
    Am Surg 75:287-90. 2009
    ....
  31. doi request reprint Increased risk of adrenal insufficiency following etomidate exposure in critically injured patients
    Bryan A Cotton
    Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, 1211 21st Ave S, 404 Medical Arts Bldg, Nashville, TN 37212, USA
    Arch Surg 143:62-7; discussion 67. 2008
    ..Timely diagnosis and treatment of adrenal insufficiency (AI) dramatically reduces mortality in trauma patients. We sought to identify risk factors and populations with a high risk of developing AI...
  32. doi request reprint Secondary abdominal compartment syndrome after severe extremity injury: are early, aggressive fluid resuscitation strategies to blame?
    Michael C Madigan
    Department of Surgery, Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Trauma 64:280-5. 2008
    ..We hypothesized that poor resuscitation techniques, including early and excessive crystalloid administration, places patients with extremity injuries at risk for developing secondary ACS...
  33. ncbi request reprint The utility of clinical and laboratory data for predicting intraabdominal injury among children
    Bryan A Cotton
    University of Missouri Hospitals and Clinics, Division of General Surgery and Critical Care, Department of Surgery, Columbia, Missouri, USA
    J Trauma 56:1068-74; discussion 1074-5. 2004
    ..The purpose of this study was to determine the utility of clinical and laboratory data for predicting the risk for IAI...
  34. doi request reprint Hyperkalemia following massive transfusion in trauma
    Brigham K Au
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Surg Res 157:284-9. 2009
    ..The purpose of the current study was to determine whether critically injured patients receiving massive transfusions are at an increased risk of hyperkalemia...
  35. doi request reprint Impact of high-dose antioxidants on outcomes in acutely injured patients
    Bryan R Collier
    Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    JPEN J Parenter Enteral Nutr 32:384-8. 2008
    ..The purpose of this study was to evaluate the impact of high-dose antioxidant administration on the mortality rate of acutely injured patients...
  36. doi request reprint Postoperative neuromuscular blocker use is associated with higher primary fascial closure rates after damage control laparotomy
    Chadi T Abouassaly
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Trauma 69:557-61. 2010
    ..The purpose of this study was to determine whether exposure to NMBA is associated a higher likelihood of primary fascial closure...
  37. pmc Transfusion therapy in hemorrhagic shock
    Timothy C Nunez
    Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, USA
    Curr Opin Crit Care 15:536-41. 2009
    ..This review will focus on this resuscitation strategy of transfusing blood products (red cells, plasma, and platelets) early and often in the exsanguinating patient...
  38. ncbi request reprint Donor conversion and organ yield in traumatic brain injury patients: missed opportunities and missed organs
    Clinton D Kemp
    Department of Surgery, Division of Trauma, Emergency Surgery, and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Trauma 64:1573-80. 2008
    ..The purpose of this study was to define donation patterns and lost donor opportunities in severe traumatic brain injury (TBI) patients...
  39. ncbi request reprint Respiratory complications and mortality risk associated with thoracic spine injury
    Bryan A Cotton
    Department of Surgery, Division of Traumatology and Surgical Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Trauma 59:1400-7; discussion 1407-9. 2005
    ..We sought to determine whether high-thoracic (HT) SCI was associated with a similar increased risk of respiratory complications and death...