Suet Nee Chen

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. pmc The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis
    Suet Nee Chen
    Center for Cardiovascular Genetics, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, and Texas Heart Institute, Houston, TX 77030, USA
    BMC Cardiovasc Disord 9:3. 2009
  2. pmc Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis
    Suet Nee Chen
    Center for Cardiovascular Genetics, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center and Texas Heart Institute, Houston, TX, USA
    BMC Med Genet 10:111. 2009
  3. pmc Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity
    Alessandra Ruggiero
    Center for Cardiovascular Genetics, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center and Texas Heart Institute, 6770 Bertner Street, Suite C900A, Houston, TX 77030, USA
    Cardiovasc Res 97:44-54. 2013
  4. pmc Human molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy
    Suet Nee Chen
    Institute of Molecular Medicine, University of Texas Health Sciences Center, Texas Heart Institute at St Luke s Episcopal Hospital, 6770 Bertner St, Suite C900A, Houston, TX 77030, USA
    Circ Res 111:907-19. 2012
  5. pmc Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms
    Raffaella Lombardi
    Center for Cardiovascular Genetics, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, and Texas Heart Institute, Houston, TX, USA
    Circulation 119:1398-407. 2009
  6. pmc Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy
    E Warwick Daw
    Department of Epidemiology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Hum Mol Genet 16:2463-71. 2007

Collaborators

  • Antonio M Gotto
  • E Warwick Daw
  • Robert Roberts
  • Raffaella Lombardi
  • Alessandra Ruggiero
  • Ali J Marian
  • Gabriela Rodriguez
  • Sandro Betocchi
  • Wenwen Li
  • James T Willerson
  • Junjie Chen
  • Igor R Efimov
  • Crystal M Ripplinger
  • Samuel A Wickline

Detail Information

Publications6

  1. pmc The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis
    Suet Nee Chen
    Center for Cardiovascular Genetics, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, and Texas Heart Institute, Houston, TX 77030, USA
    BMC Cardiovasc Disord 9:3. 2009
    ..The LCAS is a randomized placebo-control longitudinal follow-up study in patients with CAD conducted to test the effects of fluvastatin on progression or regression of coronary atherosclerosis...
  2. pmc Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis
    Suet Nee Chen
    Center for Cardiovascular Genetics, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center and Texas Heart Institute, Houston, TX, USA
    BMC Med Genet 10:111. 2009
    ....
  3. pmc Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity
    Alessandra Ruggiero
    Center for Cardiovascular Genetics, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center and Texas Heart Institute, 6770 Bertner Street, Suite C900A, Houston, TX 77030, USA
    Cardiovasc Res 97:44-54. 2013
    ..We determined potential involvement of calcineurin in the pathogenesis of HCM caused by mutations in myozenin 2 (MYOZ2), an inhibitor of calcineurin...
  4. pmc Human molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy
    Suet Nee Chen
    Institute of Molecular Medicine, University of Texas Health Sciences Center, Texas Heart Institute at St Luke s Episcopal Hospital, 6770 Bertner St, Suite C900A, Houston, TX 77030, USA
    Circ Res 111:907-19. 2012
    ..TRIM63 encoding Muscle RING Finger 1 (MuRF1) maintains muscle protein homeostasis by tagging the sarcomere proteins with ubiquitin for subsequent degradation by the ubiquitin-proteasome system (UPS)...
  5. pmc Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms
    Raffaella Lombardi
    Center for Cardiovascular Genetics, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, and Texas Heart Institute, Houston, TX, USA
    Circulation 119:1398-407. 2009
    ..We posit that treatment with N-acetylcysteine, a precursor of glutathione, the largest intracellular thiol pool against oxidative stress, could reverse cardiac hypertrophy and fibrosis in HCM...
  6. pmc Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy
    E Warwick Daw
    Department of Epidemiology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Hum Mol Genet 16:2463-71. 2007
    ....