Burgess D. Neonatal epilepsy syndromes and GEFS+: mechanistic considerations. Epilepsia. 2005;46 Suppl 10:51-8 pubmed
..Here, I discuss some of the potential mechanisms that have been uncovered recently linking mutant ion channel genes to neonatal epilepsy syndromes and GEFS+. ..
Burgess D, Noebels J. Single gene defects in mice: the role of voltage-dependent calcium channels in absence models. Epilepsy Res. 1999;36:111-22 pubmed
..A comparative analysis of channel function and neural excitability patterns in tottering, lethargic, and stargazer brain should be useful in identifying the common elements of calcium channel involvement in these absence models. ..
Burgess D, Davis C, Gefrides L, Noebels J. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome Res. 1999;9:1204-13 pubmed
..These results demonstrate the value of genome evolution models for the identification of distantly related members of gene families. ..
Burgess D, Matsuura T, Ashizawa T, Noebels J. Genetic localization of the Ca2+ channel gene CACNG2 near SCA10 on chromosome 22q13. Epilepsia. 2000;41:24-7 pubmed
..In addition, our data clarify the relation between the physical and genetic linkage maps of this region and will facilitate isolation of the SCA10 gene. ..
Burgess D, Gefrides L, Foreman P, Noebels J. A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. Genomics. 2001;71:339-50 pubmed
..The expression of distinct complements of gamma subunit isoforms in different cell types may be an important mechanism for regulating Ca2+ channel function. ..