Sarah E Bondos

Summary

Affiliation: Texas A and M Health Science Center
Country: USA

Publications

  1. doi request reprint Roles for intrinsic disorder and fuzziness in generating context-specific function in Ultrabithorax, a Hox transcription factor
    Sarah E Bondos
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas, USA
    Adv Exp Med Biol 725:86-105. 2012
  2. pmc Media composition influences yeast one- and two-hybrid results
    Ying Liu
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005 USA
    Biol Proced Online 13:6. 2011
  3. doi request reprint Size dictates mechanical properties for protein fibers self-assembled by the Drosophila hox transcription factor ultrabithorax
    Zhao Huang
    Departments of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, United States
    Biomacromolecules 11:3644-51. 2010
  4. pmc Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila hox protein ultrabithorax
    Ying Liu
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA
    J Biol Chem 283:20874-87. 2008
  5. ncbi request reprint Physical and genetic interactions link hox function with diverse transcription factors and cell signaling proteins
    Sarah E Bondos
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, USA
    Mol Cell Proteomics 5:824-34. 2006
  6. doi request reprint The Drosophila transcription factor ultrabithorax self-assembles into protein-based biomaterials with multiple morphologies
    Alexandra M Greer
    Department of Biochemistry and Cell Biology, Rice University, 6100 South Main Street, Houston, Texas 77005, USA
    Biomacromolecules 10:829-37. 2009
  7. ncbi request reprint Hox transcription factor ultrabithorax Ib physically and genetically interacts with disconnected interacting protein 1, a double-stranded RNA-binding protein
    Sarah E Bondos
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, USA
    J Biol Chem 279:26433-44. 2004
  8. pmc Internal regulatory interactions determine DNA binding specificity by a Hox transcription factor
    Ying Liu
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA
    J Mol Biol 390:760-74. 2009
  9. pmc The intrinsically disordered regions of the Drosophila melanogaster Hox protein ultrabithorax select interacting proteins based on partner topology
    Hao Ching Hsiao
    Reynolds Medical Building, Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas, United States of America
    PLoS ONE 9:e108217. 2014
  10. doi request reprint Measuring Hox-DNA binding by electrophoretic mobility shift analysis
    Kelly Churion
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, TX, 77843 1114, USA
    Methods Mol Biol 1196:211-30. 2014

Collaborators

  • Ying Liu
  • Daniel J Catanese
  • Liskin Swint-Kruse
  • Angela M Arenas-Gamboa
  • Jan L Patterson
  • Hao Ching Hsiao
  • Kathleen S Matthews
  • Zhao Huang
  • Kelly Churion
  • Kelly A Churion
  • Yang Lu
  • Jun Lou
  • Alexandra M Greer
  • Jean Philippe Pellois
  • David W Howell
  • Ting Yi Wang
  • Allison Rice-Ficht
  • Colette A Abbey
  • Kayla J Bayless
  • Kristopher E Jordy
  • Kim L Gonzalez
  • Jaimin Shah
  • Ravish Majithia
  • Kenith Meissner
  • Ashley Oriakhi

Detail Information

Publications15

  1. doi request reprint Roles for intrinsic disorder and fuzziness in generating context-specific function in Ultrabithorax, a Hox transcription factor
    Sarah E Bondos
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas, USA
    Adv Exp Med Biol 725:86-105. 2012
    ..These intrinsic disorder-based regulatory mechanisms are likely to be critical for allowing Ubx to sense tissue identity and respond by implementing a context-specific gene regulatory cascade...
  2. pmc Media composition influences yeast one- and two-hybrid results
    Ying Liu
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005 USA
    Biol Proced Online 13:6. 2011
    ..While altering media preparation may optimize signal differences for individual experiments, media preparation must be reported in detail to replicate studies and accurately compare results from different experiments...
  3. doi request reprint Size dictates mechanical properties for protein fibers self-assembled by the Drosophila hox transcription factor ultrabithorax
    Zhao Huang
    Departments of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, United States
    Biomacromolecules 11:3644-51. 2010
    ..Controlling fiber size and generating fiber superstructures is a facile way to manipulate the mechanical characteristics of protein fibers and rationally engineer macroscale protein-based materials with desirable properties...
  4. pmc Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila hox protein ultrabithorax
    Ying Liu
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA
    J Biol Chem 283:20874-87. 2008
    ..The amino acid sequences of I2 and much of the I1 and R regions vary significantly among Ultrabithorax orthologues, potentially diversifying Hox-DNA interactions...
  5. ncbi request reprint Physical and genetic interactions link hox function with diverse transcription factors and cell signaling proteins
    Sarah E Bondos
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, USA
    Mol Cell Proteomics 5:824-34. 2006
    ..Thus, Hox.transcription factor complexes may integrate a variety of positional cues, generating the specificity and versatility required for context-dependent Hox function...
  6. doi request reprint The Drosophila transcription factor ultrabithorax self-assembles into protein-based biomaterials with multiple morphologies
    Alexandra M Greer
    Department of Biochemistry and Cell Biology, Rice University, 6100 South Main Street, Houston, Texas 77005, USA
    Biomacromolecules 10:829-37. 2009
    ....
  7. ncbi request reprint Hox transcription factor ultrabithorax Ib physically and genetically interacts with disconnected interacting protein 1, a double-stranded RNA-binding protein
    Sarah E Bondos
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005, USA
    J Biol Chem 279:26433-44. 2004
    ..The strong interaction of Ubx with an RNA-binding protein suggests a wider range of proteins may influence Ubx function than previously appreciated...
  8. pmc Internal regulatory interactions determine DNA binding specificity by a Hox transcription factor
    Ying Liu
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA
    J Mol Biol 390:760-74. 2009
    ..Since most nonhomeodomain regions are not conserved between Hox family members, these regulatory interactions have the potential to diversify binding by the highly homologous Hox homeodomains...
  9. pmc The intrinsically disordered regions of the Drosophila melanogaster Hox protein ultrabithorax select interacting proteins based on partner topology
    Hao Ching Hsiao
    Reynolds Medical Building, Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas, United States of America
    PLoS ONE 9:e108217. 2014
    ....
  10. doi request reprint Measuring Hox-DNA binding by electrophoretic mobility shift analysis
    Kelly Churion
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, TX, 77843 1114, USA
    Methods Mol Biol 1196:211-30. 2014
    ..This versatile assay system can be adjusted based on specific needs to measure other parameters, including the kinetic association and dissociation constants (k a and k d) and the formation of heterologous protein-protein interactions. ..
  11. doi request reprint Identifying solubility-promoting buffers for intrinsically disordered proteins prior to purification
    Kelly A Churion
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, TX, USA
    Methods Mol Biol 896:415-27. 2012
    ..This approach allows identification of solubility-promoting buffers prior to the initial protein purification...
  12. doi request reprint Materials composed of the Drosophila melanogaster protein ultrabithorax are cytocompatible
    Jan L Patterson
    Department of Molecular and Cellular Medicine, College of Medicine, Texas A and M Health Science Center, College Station, Texas 77843 1114
    J Biomed Mater Res A 102:97-104. 2014
    ..Thus, Ubx fibers are cytocompatible with cultured primary human vascular cells...
  13. ncbi request reprint Detection and prevention of protein aggregation before, during, and after purification
    Sarah E Bondos
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77251 1892, USA
    Anal Biochem 316:223-31. 2003
    ..From the results presented, this technique can be applied to a variety of proteins...
  14. pmc Flexibility and Disorder in Gene Regulation: LacI/GalR and Hox Proteins
    Sarah E Bondos
    From the Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas 77843
    J Biol Chem 290:24669-77. 2015
    ..The widespread importance of structural disorder in gene regulatory proteins may derive from the need for flexibility in signal response and, particularly in eukaryotes, in protein partner selection...
  15. doi request reprint Materials composed of the Drosophila Hox protein Ultrabithorax are biocompatible and nonimmunogenic
    Jan L Patterson
    Department of Molecular and Cellular Medicine, Texas A and M Health Science Center, College Station, Texas, 77843
    J Biomed Mater Res A 103:1546-53. 2015
    ..The minimal effects observed are comparable with those induced by biomaterials used successfully in vivo. We conclude Ubx materials are biocompatible and nonimmunogenic...