Susan A Bloomfield

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. doi request reprint Disuse osteopenia
    Susan A Bloomfield
    Department of Health and Kinesiology, MS 4243, Texas A and M University, College Station, TX, 77843, USA
    Curr Osteoporos Rep 8:91-7. 2010
  2. ncbi request reprint Does altered blood flow to bone in microgravity impact on mechanotransduction?
    S A Bloomfield
    Bone Biology Laboratory, Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    J Musculoskelet Neuronal Interact 6:324-6. 2006
  3. ncbi request reprint Site- and compartment-specific changes in bone with hindlimb unloading in mature adult rats
    S A Bloomfield
    Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    Bone 31:149-57. 2002
  4. doi request reprint Food restriction and simulated microgravity: effects on bone and serum leptin
    Kyunghwa Baek
    Dept of Health and Kinesiology Texas A and M, Univ, College Station, TX 77843 4243, USA
    J Appl Physiol (1985) 104:1086-93. 2008
  5. ncbi request reprint Partial weight bearing does not prevent musculoskeletal losses associated with disuse
    Joshua M Swift
    1Department of Health and Kinesiology, Texas A and M University, College Station, TX 2Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN 3Department of Biomedical Engineering, Texas A and M University, College Station, TX 4Department of Mechanical Engineering, Texas A and M University, College Station, TX and 5Department of Nutrition and Food Science, Texas A and M University, College Station, TX
    Med Sci Sports Exerc 45:2052-60. 2013
  6. ncbi request reprint β-1 adrenergic agonist mitigates unloading-induced bone loss by maintaining formation
    Joshua M Swift
    Department of Health and Kinesiology, Texas A and M University, College Station, TX, USA
    Med Sci Sports Exerc 45:1665-73. 2013
  7. doi request reprint Blocking β-adrenergic signaling attenuates reductions in circulating leptin, cancellous bone mass, and marrow adiposity seen with dietary energy restriction
    Kyunghwa Baek
    Department of Health and Kinesiology and Intercollegiate Graduate Faculty of Nutrition, Texas A and M University, College Station, Texas 77843, USA
    J Appl Physiol (1985) 113:1792-801. 2012
  8. doi request reprint Cancellous bone formation response to simulated resistance training during disuse is blunted by concurrent alendronate treatment
    Joshua M Swift
    Departments of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    J Bone Miner Res 26:2140-50. 2011
  9. doi request reprint Previous exposure to simulated microgravity does not exacerbate bone loss during subsequent exposure in the proximal tibia of adult rats
    Yasaman Shirazi-Fard
    Department of Biomedical Engineering, Texas A and M University, College Station, TX 77843, USA
    Bone 56:461-73. 2013
  10. doi request reprint Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone loss
    Kyunghwa Baek
    Department of Health and Kinesiology and Intercollegiate Graduate Faculty of Nutrition, Texas A and M University, College Station, Texas, USA
    J Bone Miner Res 24:792-9. 2009

Collaborators

Detail Information

Publications31

  1. doi request reprint Disuse osteopenia
    Susan A Bloomfield
    Department of Health and Kinesiology, MS 4243, Texas A and M University, College Station, TX, 77843, USA
    Curr Osteoporos Rep 8:91-7. 2010
    ..Exciting new data using hindlimb unloaded rodents are defining the important role of the protein sclerostin in regulating Wnt/beta-catenin signaling and subsequent loss of bone during periods of disuse...
  2. ncbi request reprint Does altered blood flow to bone in microgravity impact on mechanotransduction?
    S A Bloomfield
    Bone Biology Laboratory, Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    J Musculoskelet Neuronal Interact 6:324-6. 2006
  3. ncbi request reprint Site- and compartment-specific changes in bone with hindlimb unloading in mature adult rats
    S A Bloomfield
    Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    Bone 31:149-57. 2002
    ..Given the sharp decline in BFR for midshaft cortical bone, it appears likely that deficits in BMD, area, or mechanical properties would develop with longer duration unloading...
  4. doi request reprint Food restriction and simulated microgravity: effects on bone and serum leptin
    Kyunghwa Baek
    Dept of Health and Kinesiology Texas A and M, Univ, College Station, TX 77843 4243, USA
    J Appl Physiol (1985) 104:1086-93. 2008
    ....
  5. ncbi request reprint Partial weight bearing does not prevent musculoskeletal losses associated with disuse
    Joshua M Swift
    1Department of Health and Kinesiology, Texas A and M University, College Station, TX 2Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN 3Department of Biomedical Engineering, Texas A and M University, College Station, TX 4Department of Mechanical Engineering, Texas A and M University, College Station, TX and 5Department of Nutrition and Food Science, Texas A and M University, College Station, TX
    Med Sci Sports Exerc 45:2052-60. 2013
    ....
  6. ncbi request reprint β-1 adrenergic agonist mitigates unloading-induced bone loss by maintaining formation
    Joshua M Swift
    Department of Health and Kinesiology, Texas A and M University, College Station, TX, USA
    Med Sci Sports Exerc 45:1665-73. 2013
    ..The purpose of this study was to evaluate the effects of a beta-1 adrenergic (Adrb1) agonist, dobutamine (DOB), on disuse-induced changes in bone integrity during 28 d of hindlimb unloading (HU)...
  7. doi request reprint Blocking β-adrenergic signaling attenuates reductions in circulating leptin, cancellous bone mass, and marrow adiposity seen with dietary energy restriction
    Kyunghwa Baek
    Department of Health and Kinesiology and Intercollegiate Graduate Faculty of Nutrition, Texas A and M University, College Station, Texas 77843, USA
    J Appl Physiol (1985) 113:1792-801. 2012
    ..These data suggest an important role for β-adrenoreceptor signaling pathway in the cancellous bone and marrow fat response to energy restriction...
  8. doi request reprint Cancellous bone formation response to simulated resistance training during disuse is blunted by concurrent alendronate treatment
    Joshua M Swift
    Departments of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    J Bone Miner Res 26:2140-50. 2011
    ..These results demonstrate the anabolic effect of a low volume of high-intensity muscle contractions during disuse and suggest that both bone resorption and bone formation are suppressed when SRT is combined with bisphosphonate treatment...
  9. doi request reprint Previous exposure to simulated microgravity does not exacerbate bone loss during subsequent exposure in the proximal tibia of adult rats
    Yasaman Shirazi-Fard
    Department of Biomedical Engineering, Texas A and M University, College Station, TX 77843, USA
    Bone 56:461-73. 2013
    ....
  10. doi request reprint Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone loss
    Kyunghwa Baek
    Department of Health and Kinesiology and Intercollegiate Graduate Faculty of Nutrition, Texas A and M University, College Station, Texas, USA
    J Bone Miner Res 24:792-9. 2009
    ..A direct effect of beta-adrenergic blockade on bone cells during HU may be enhanced by an indirect effect mitigating reductions in circulating leptin, possibly through disinhibition of leptin release from adipocytes...
  11. ncbi request reprint Simulated resistance training during hindlimb unloading abolishes disuse bone loss and maintains muscle strength
    Joshua M Swift
    Department of Health, Texas A and M University, College Station, Texas 77843 4243, USA
    J Bone Miner Res 25:564-74. 2010
    ..These results demonstrate that high-intensity muscle contractions, independent of weight-bearing forces, can effectively mitigate losses in muscle strength and provide a potent stimulus to bone during prolonged disuse...
  12. ncbi request reprint Hindlimb unloading has a greater effect on cortical compared with cancellous bone in mature female rats
    Matthew R Allen
    Department of Health and Kinesiology, Texas A and M University, College Station 77843 4243, USA
    J Appl Physiol 94:642-50. 2003
    ..These results suggest that cortical bone, rather than cancellous bone, is more prominently affected by unloading in skeletally mature retired breeder female rats...
  13. doi request reprint Restriction of dietary energy intake has a greater impact on bone integrity than does restriction of calcium in exercising female rats
    Sibyl N Swift
    Department of Health and Kinesiology, Texas A and M University, College Station, TX, USA
    J Nutr 142:1038-45. 2012
    ....
  14. doi request reprint Discordant recovery of bone mass and mechanical properties during prolonged recovery from disuse
    Yasaman Shirazi-Fard
    Department of Biomedical Engineering, Texas A and M University, College Station, TX 77843, USA
    Bone 52:433-43. 2013
    ..More complete utility of the rat PTM as a model in this case, however, depends upon meaningful characterization of changes in mechanical properties as well...
  15. ncbi request reprint Differential bone and muscle recovery following hindlimb unloading in skeletally mature male rats
    M R Allen
    Department of Health and Kinesiology, Texas A and M University, College Station, TX 77840, USA
    J Musculoskelet Neuronal Interact 6:217-25. 2006
    ....
  16. ncbi request reprint Effects of eccentric exercise training on cortical bone and muscle strength in the estrogen-deficient mouse
    M J Hubal
    Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    J Appl Physiol 98:1674-81. 2005
    ..These data indicate that eccentric exercise training in adult mice can significantly increase bone stiffness, despite the absence of ovarian hormones...
  17. ncbi request reprint Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle
    John M Lawler
    Redox Biology and Cell Signaling Laboratory, Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
    Free Radic Biol Med 35:9-16. 2003
    ..6% and hindlimb muscle DCFH-DA oxidation by 162.1%. These results indicate that hindlimb unloading results in a disruption of antioxidant status, elevation of hydroperoxides, and an increase in oxidative stress...
  18. ncbi request reprint Effects of vigorous exercise training and beta-agonist administration on bone response to hindlimb suspension
    S A Bloomfield
    School of Health, Physical Education, and Recreation and Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210 1290
    J Appl Physiol (1985) 83:172-8. 1997
    ..In summary, vigorous Ex before Sus does not affect loss of bone mass due to unloading; Dob effectively maintains CBA in Sed rats subjected to suspension...
  19. ncbi request reprint Changes in musculoskeletal structure and function with prolonged bed rest
    S A Bloomfield
    Department of Health and Kinesiology, Texas A and M University, College Station 77843 4243, USA
    Med Sci Sports Exerc 29:197-206. 1997
    ..Practical implications for exercise professionals working with individuals confined to bed rest are discussed...
  20. ncbi request reprint Bone mass and endocrine adaptations to training in spinal cord injured individuals
    S A Bloomfield
    Department of Health and Kinesiology, Texas A and M University, College Station 77843 4243, USA
    Bone 19:61-8. 1996
    ..Calcium supplementation from the outset of training in osteopenic individuals may be advisable to prevent training-induced increases in PTH...
  21. ncbi request reprint Estradiol effect on anterior crural muscles-tibial bone relationship and susceptibility to injury
    G L Warren
    Muscle Biology Laboratory, Texas A and M University, College Station 77843, USA
    J Appl Physiol (1985) 80:1660-5. 1996
    ..53). In conclusion, the functional relationship of bone to muscle and the susceptibility to injury in bone are not altered by the presence of E2 in ovariectomized mice; however, E2 does increase injury susceptibility in the EDL muscle...
  22. doi request reprint Altered bone mass, geometry and mechanical properties during the development and progression of type 2 diabetes in the Zucker diabetic fatty rat
    Rhonda D Prisby
    Departments of Health and Kinesiology Intercollegiate Faculty of Nutrition Mechanical Engineering, Texas A and M University, College Station, Texas 77843, USA
    J Endocrinol 199:379-88. 2008
    ....
  23. pmc Increased resistance during jump exercise does not enhance cortical bone formation
    Ramon D Boudreaux
    1Department of Biomedical Engineering, Texas A and M University, College Station, TX 2Department of Health and Kinesiology, Texas A and M University, College Station, TX and 3Department of Mechanical Engineering, Texas A and M University, College Station, TX
    Med Sci Sports Exerc 46:982-9. 2014
    ..This study sought to elucidate the effects of a low- and high-load jump resistance exercise (RE) training protocol on cortical bone of the tibia and femur mid-diaphyses...
  24. ncbi request reprint Molt performance and bone density of cortical, medullary, and cancellous bone in laying hens during feed restriction or alfalfa-based feed molt
    W K Kim
    Department of Poultry Science, Texas A and M University, College Station, TX 77843, USA
    Poult Sci 86:1821-30. 2007
    ....
  25. ncbi request reprint Cellular and molecular mechanisms for the bone response to mechanical loading
    S A Bloomfield
    Department of Health and Kinesiology, Texas A and M University, College Station 77843-4243, USA
    Int J Sport Nutr Exerc Metab 11:S128-36. 2001
    ..The efficiency of this process is also impaired in the aged animal, yet what remains undefined is at what step mechanotransduction is affected...
  26. doi request reprint Increased training loads do not magnify cancellous bone gains with rodent jump resistance exercise
    J M Swift
    Department of Health and Kinesiology, MS 4243, Texas A and M University, College Station, TX 77843 4243, USA
    J Appl Physiol (1985) 109:1600-7. 2010
    ..These results suggest that jumping at minimal resistance provides a similar anabolic stimulus to cancellous bone as jumping at loads exceeding body mass...
  27. ncbi request reprint The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific
    Joseph M Wallace
    Department of Biomedical Engineering, The University of Michigan, Ann Arbor, MI 48109 2099, and Henry Ford Hospital, Bone and Joint Center, Detroit, MI 48202, USA
    Bone 39:106-16. 2006
    ....
  28. ncbi request reprint American College of Sports Medicine Position Stand: physical activity and bone health
    Wendy M Kohrt
    Med Sci Sports Exerc 36:1985-96. 2004
  29. ncbi request reprint Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089)
    Ramesh Narayanan
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Bone 35:134-43. 2004
    ....
  30. pmc Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific
    Joseph M Wallace
    The University of Michigan, Department of Biomedical Engineering, Ann Arbor, MI, USA
    Bone 40:1120-7. 2007
    ..Exercise also influenced the quality of this forming bone, significantly impacting structural and tissue-level mechanical properties...
  31. ncbi request reprint Biglycan deficiency interferes with ovariectomy-induced bone loss
    Karina L Nielsen
    Nordic Bioscience A S, Herlev, Denmark
    J Bone Miner Res 18:2152-8. 2003
    ....