Research Topics
| Susan A BloomfieldSummaryAffiliation: Texas A and M University Country: USA Publications
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Detail Information
Publications
Disuse osteopeniaSusan A Bloomfield
Department of Health and Kinesiology, MS 4243, Texas A and M University, College Station, TX, 77843, USA
Curr Osteoporos Rep 8:91-7. 2010..Exciting new data using hindlimb unloaded rodents are defining the important role of the protein sclerostin in regulating Wnt/beta-catenin signaling and subsequent loss of bone during periods of disuse...
Site- and compartment-specific changes in bone with hindlimb unloading in mature adult ratsS A Bloomfield
Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
Bone 31:149-57. 2002..Given the sharp decline in BFR for midshaft cortical bone, it appears likely that deficits in BMD, area, or mechanical properties would develop with longer duration unloading...- Does altered blood flow to bone in microgravity impact on mechanotransduction?S A Bloomfield
Bone Biology Laboratory, Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
J Musculoskelet Neuronal Interact 6:324-6. 2006 - Food restriction and simulated microgravity: effects on bone and serum leptinKyunghwa Baek
Dept of Health and Kinesiology Texas A and M, Univ, College Station, TX 77843 4243, USA
J Appl Physiol 104:1086-93. 2008.... - Cancellous bone formation response to simulated resistance training during disuse is blunted by concurrent alendronate treatmentJoshua M Swift
Departments of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
J Bone Miner Res 26:2140-50. 2011..These results demonstrate the anabolic effect of a low volume of high-intensity muscle contractions during disuse and suggest that both bone resorption and bone formation are suppressed when SRT is combined with bisphosphonate treatment... - Simulated resistance training during hindlimb unloading abolishes disuse bone loss and maintains muscle strengthJoshua M Swift
Department of Health, Texas A and M University, College Station, Texas 77843 4243, USA
J Bone Miner Res 25:564-74. 2010..These results demonstrate that high-intensity muscle contractions, independent of weight-bearing forces, can effectively mitigate losses in muscle strength and provide a potent stimulus to bone during prolonged disuse... - Restriction of dietary energy intake has a greater impact on bone integrity than does restriction of calcium in exercising female ratsSibyl N Swift
Department of Health and Kinesiology, Texas A and M University, College Station, TX, USA
J Nutr 142:1038-45. 2012.... - Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone lossKyunghwa Baek
Department of Health and Kinesiology and Intercollegiate Graduate Faculty of Nutrition, Texas A and M University, College Station, Texas, USA
J Bone Miner Res 24:792-9. 2009..A direct effect of beta-adrenergic blockade on bone cells during HU may be enhanced by an indirect effect mitigating reductions in circulating leptin, possibly through disinhibition of leptin release from adipocytes... - Discordant recovery of bone mass and mechanical properties during prolonged recovery from disuseYasaman Shirazi-Fard
Department of Biomedical Engineering, Texas A and M University, College Station, TX 77843, USA
Bone 52:433-43. 2013..More complete utility of the rat PTM as a model in this case, however, depends upon meaningful characterization of changes in mechanical properties as well... - Differential bone and muscle recovery following hindlimb unloading in skeletally mature male ratsM R Allen
Department of Health and Kinesiology, Texas A and M University, College Station, TX 77840, USA
J Musculoskelet Neuronal Interact 6:217-25. 2006.... - Effects of eccentric exercise training on cortical bone and muscle strength in the estrogen-deficient mouseM J Hubal
Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843-4243, USA
J Appl Physiol 98:1674-81. 2005..These data indicate that eccentric exercise training in adult mice can significantly increase bone stiffness, despite the absence of ovarian hormones... - Estradiol effect on anterior crural muscles-tibial bone relationship and susceptibility to injuryG L Warren
Muscle Biology Laboratory, Texas A and M University, College Station 77843, USA
J Appl Physiol 80:1660-5. 1996..53). In conclusion, the functional relationship of bone to muscle and the susceptibility to injury in bone are not altered by the presence of E2 in ovariectomized mice; however, E2 does increase injury susceptibility in the EDL muscle... - Bone mass and endocrine adaptations to training in spinal cord injured individualsS A Bloomfield
Department of Health and Kinesiology, Texas A and M University, College Station 77843 4243, USA
Bone 19:61-8. 1996..Calcium supplementation from the outset of training in osteopenic individuals may be advisable to prevent training-induced increases in PTH... - Changes in musculoskeletal structure and function with prolonged bed restS A Bloomfield
Department of Health and Kinesiology, Texas A and M University, College Station 77843 4243, USA
Med Sci Sports Exerc 29:197-206. 1997..Practical implications for exercise professionals working with individuals confined to bed rest are discussed... - Effects of vigorous exercise training and beta-agonist administration on bone response to hindlimb suspensionS A Bloomfield
School of Health, Physical Education, and Recreation and Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210 1290
J Appl Physiol 83:172-8. 1997..In summary, vigorous Ex before Sus does not affect loss of bone mass due to unloading; Dob effectively maintains CBA in Sed rats subjected to suspension... - Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscleJohn M Lawler
Redox Biology and Cell Signaling Laboratory, Department of Health and Kinesiology, Texas A and M University, College Station, TX 77843 4243, USA
Free Radic Biol Med 35:9-16. 2003..6% and hindlimb muscle DCFH-DA oxidation by 162.1%. These results indicate that hindlimb unloading results in a disruption of antioxidant status, elevation of hydroperoxides, and an increase in oxidative stress... - Altered bone mass, geometry and mechanical properties during the development and progression of type 2 diabetes in the Zucker diabetic fatty ratRhonda D Prisby
Departments of Health and Kinesiology Intercollegiate Faculty of Nutrition Mechanical Engineering, Texas A and M University, College Station, Texas 77843, USA
J Endocrinol 199:379-88. 2008.... - Blocking β-adrenergic signaling attenuates reductions in circulating leptin, cancellous bone mass, and marrow adiposity seen with dietary energy restrictionKyunghwa Baek
Department of Health and Kinesiology and Intercollegiate Graduate Faculty of Nutrition, Texas A and M University, College Station, Texas 77843, USA
J Appl Physiol 113:1792-801. 2012..These data suggest an important role for β-adrenoreceptor signaling pathway in the cancellous bone and marrow fat response to energy restriction... - Molt performance and bone density of cortical, medullary, and cancellous bone in laying hens during feed restriction or alfalfa-based feed moltW K Kim
Department of Poultry Science, Texas A and M University, College Station, TX 77843, USA
Poult Sci 86:1821-30. 2007.... - Cellular and molecular mechanisms for the bone response to mechanical loadingS A Bloomfield
Department of Health and Kinesiology, Texas A and M University, College Station 77843-4243, USA
Int J Sport Nutr Exerc Metab 11:S128-36. 2001..The efficiency of this process is also impaired in the aged animal, yet what remains undefined is at what step mechanotransduction is affected... - Increased training loads do not magnify cancellous bone gains with rodent jump resistance exerciseJ M Swift
Department of Health and Kinesiology, MS 4243, Texas A and M University, College Station, TX 77843 4243, USA
J Appl Physiol 109:1600-7. 2010..These results suggest that jumping at minimal resistance provides a similar anabolic stimulus to cancellous bone as jumping at loads exceeding body mass... - Hindlimb unloading has a greater effect on cortical compared with cancellous bone in mature female ratsMatthew R Allen
TX A and M U, College Station
J Appl Physiol 94:642-50. 2003..These results suggest that cortical bone, rather than cancellous bone, is more prominently affected by unloading in skeletally mature retired breeder female rats... 
Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specificJoseph M Wallace
The University of Michigan, Department of Biomedical Engineering, Ann Arbor, MI, USA
Bone 40:1120-7. 2007..Exercise also influenced the quality of this forming bone, significantly impacting structural and tissue-level mechanical properties...- Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089)Ramesh Narayanan
TX A and M U, College Station
Bone 35:134-43. 2004.... - The mechanical phenotype of biglycan-deficient mice is bone- and gender-specificJoseph M Wallace
Department of Biomedical Engineering, The University of Michigan, Ann Arbor, MI 48109 2099, and Henry Ford Hospital, Bone and Joint Center, Detroit, MI 48202, USA
Bone 39:106-16. 2006.... - American College of Sports Medicine Position Stand: physical activity and bone healthWendy M Kohrt
Med Sci Sports Exerc 36:1985-96. 2004 - Biglycan deficiency interferes with ovariectomy-induced bone lossKarina L Nielsen
Nordic Bioscience A S, Herlev, Denmark
J Bone Miner Res 18:2152-8. 2003....