Roger J Bick

Summary

Affiliation: Texas Medical Center
Country: USA

Publications

  1. ncbi request reprint Localization of calcitonin gene-related peptide in cardiomyocytes: comparison of neonatal and dedifferentiating cells to adult myocytes
    Roger J Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, University of Texas Health Science Center, 6431 Fannin Street, Houston, TX 77030, USA
    Peptides 26:331-6. 2005
  2. ncbi request reprint The effects of CGRP on calcium transients of dedifferentiating cultured adult rat cardiomyocytes compared to non-cultured adult cardiomyocytes: possible protective and deleterious results in cardiac function
    Mya C Schiess
    Department of Neurology, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Peptides 26:525-30. 2005
  3. pmc Do binucleate cardiomyocytes have a role in myocardial repair? Insights using isolated rodent myocytes and cell culture
    Michael J Stephen
    Department of Pathology, University of Texas Medical School at Houston, Texas, USA
    Open Cardiovasc Med J 3:1-7. 2009
  4. pmc Upregulation of defensins in burn sheep small intestine
    Brian J Poindexter
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston
    Eplasty 10:e6. 2009
  5. pmc Alterations in content and localization of defensins in rat ileum and jejunum following ischemia-reperfusion. Specific peptides, in specific places, for specific jobs?
    Rosemary A Kozar
    Eplasty 11:e8. 2011
  6. ncbi request reprint Determination of the site of action of calcitonin gene-related peptide in the alteration of intracellular calcium levels in adult and neonatal rodent myocytes
    Roger J Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Peptides 26:2231-8. 2005
  7. ncbi request reprint Fluorescence imaging microscopy of cellular markers in ischemic vs non-ischemic cardiomyopathy after left ventricular unloading
    Roger J Bick
    Department of Organ Transplantation Cardiovascular Pathology, Texas Heart Institute and St Lukes Episcopal Hospital, Houston, Texas, USA
    J Heart Lung Transplant 24:454-61. 2005
  8. ncbi request reprint Left ventricular unloading with an assist device results in receptor relocalization as well as increased beta-adrenergic receptor numbers: are these changes indications for outcome?
    Roger J Bick
    Department of Cardiovascular Anesthesiology, The Texas Heart Institute and St Luke s Episcopal Hospital, Houston, TX, USA
    J Card Surg 20:332-6. 2005
  9. ncbi request reprint Cytokines disrupt intracellular patterns of Parkinson's disease-associated proteins alpha-synuclein, tau and ubiquitin in cultured glial cells
    Roger J Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Texas 77030, USA
    Brain Res 1217:203-12. 2008
  10. ncbi request reprint The immune-enhancing enteral agents arginine and glutamine differentially modulate gut barrier function following mesenteric ischemia/reperfusion
    Rosemary A Kozar
    Departments of Surgery, University of Texas Houston, Houston, Texas, USA
    J Trauma 57:1150-6. 2004

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Localization of calcitonin gene-related peptide in cardiomyocytes: comparison of neonatal and dedifferentiating cells to adult myocytes
    Roger J Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, University of Texas Health Science Center, 6431 Fannin Street, Houston, TX 77030, USA
    Peptides 26:331-6. 2005
    ....
  2. ncbi request reprint The effects of CGRP on calcium transients of dedifferentiating cultured adult rat cardiomyocytes compared to non-cultured adult cardiomyocytes: possible protective and deleterious results in cardiac function
    Mya C Schiess
    Department of Neurology, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Peptides 26:525-30. 2005
    ....
  3. pmc Do binucleate cardiomyocytes have a role in myocardial repair? Insights using isolated rodent myocytes and cell culture
    Michael J Stephen
    Department of Pathology, University of Texas Medical School at Houston, Texas, USA
    Open Cardiovasc Med J 3:1-7. 2009
    ..Such possibilities would extend cardiac disease associated stem cell research and therapy options, while producing valuable insights into developmental and death pathways of binucleate cardiomyocytes (word count 183)...
  4. pmc Upregulation of defensins in burn sheep small intestine
    Brian J Poindexter
    Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston
    Eplasty 10:e6. 2009
    ..Conclusion: That while each of these human antimicrobials is present in multiple layers of sheep small intestine, SBD-2, SBD-3, SNP-1, and LL-37 are upregulated in the specific layers of the small intestine...
  5. pmc Alterations in content and localization of defensins in rat ileum and jejunum following ischemia-reperfusion. Specific peptides, in specific places, for specific jobs?
    Rosemary A Kozar
    Eplasty 11:e8. 2011
    ..Conclusion: Ischemia-reperfusion injury caused changes in antimicrobial content in defined areas, and these different regulations might reflect the specific roles of jejunum versus ileum...
  6. ncbi request reprint Determination of the site of action of calcitonin gene-related peptide in the alteration of intracellular calcium levels in adult and neonatal rodent myocytes
    Roger J Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA
    Peptides 26:2231-8. 2005
    ..Finally, our collaborative studies in human myocardium using fluorescence deconvolution microscopy revealed that CGRP localization was found in a pattern similar to that of the sarcolemmal L-type calcium channel...
  7. ncbi request reprint Fluorescence imaging microscopy of cellular markers in ischemic vs non-ischemic cardiomyopathy after left ventricular unloading
    Roger J Bick
    Department of Organ Transplantation Cardiovascular Pathology, Texas Heart Institute and St Lukes Episcopal Hospital, Houston, Texas, USA
    J Heart Lung Transplant 24:454-61. 2005
    ..To establish that unloading had been achieved, levels of atrial natriuretic protein were determined...
  8. ncbi request reprint Left ventricular unloading with an assist device results in receptor relocalization as well as increased beta-adrenergic receptor numbers: are these changes indications for outcome?
    Roger J Bick
    Department of Cardiovascular Anesthesiology, The Texas Heart Institute and St Luke s Episcopal Hospital, Houston, TX, USA
    J Card Surg 20:332-6. 2005
    ..The use of left ventricular (LV) assist devices (LVADs) can improve performance and recovery of failing human hearts...
  9. ncbi request reprint Cytokines disrupt intracellular patterns of Parkinson's disease-associated proteins alpha-synuclein, tau and ubiquitin in cultured glial cells
    Roger J Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Texas 77030, USA
    Brain Res 1217:203-12. 2008
    ..These results support the postulate that specific cytokines affect temporal protein changes with concomitant pattern disruptions, possibly reflecting a mechanism of cell dysfunction in Parkinson's degeneration...
  10. ncbi request reprint The immune-enhancing enteral agents arginine and glutamine differentially modulate gut barrier function following mesenteric ischemia/reperfusion
    Rosemary A Kozar
    Departments of Surgery, University of Texas Houston, Houston, Texas, USA
    J Trauma 57:1150-6. 2004
    ..While recent data has shown that glutamine is beneficial, arginine may be harmful. We therefore hypothesized that the immune-enhancing agents, glutamine and arginine, differentially modulate gut barrier function...
  11. doi request reprint Location and density of alpha- and beta-adrenoreceptor sub-types in myocardium after mechanical left ventricular unloading
    Pippa M Schnee
    Department of Cardiovascular Surgical Research, Texas Heart Institute, St Luke s Episcopal Hospital, Houston, Texas, USA
    J Heart Lung Transplant 27:710-7. 2008
    ..We hypothesized that not all subtypes of alpha- and beta-adrenoreceptors undergo similar upregulation and redistribution in human myocardium after mechanical unloading with an assist device...
  12. ncbi request reprint Fluorescence microscopy and 3D image reconstruction of cytokine initiated disruption of the Parkinson disease associated proteins alpha-synuclein, tau and ubiquitin in cultured glial cells
    Kha Dinh
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, 6431 Fannin Street, MSB 2 288, Houston, TX 77030, USA
    Cytokine 45:179-83. 2009
    ....
  13. pmc CSF from Parkinson disease patients differentially affects cultured microglia and astrocytes
    Mya C Schiess
    Department of Neurology, University of Texas Medical School at Houston, Houston, Texas 77030, USA
    BMC Neurosci 11:151. 2010
    ..Outcome measures included manually counted cell growth patterns from day 1-8; α-synuclein density and distribution by antibody tagged 3D model stacked deconvoluted fluorescent imaging...
  14. ncbi request reprint Oleandrin produces changes in intracellular calcium levels in isolated cardiomyocytes: a real-time fluorescence imaging study comparing adult to neonatal cardiomyocytes
    Brian J Poindexter
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Texas 77030, USA
    J Toxicol Environ Health A 70:568-74. 2007
    ..6.1.3], and/or dysfunction of sarcolemmal calcium release channels...
  15. ncbi request reprint A comparison of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocytes
    Michelle E Rodriguez
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, University of Texas Health Science Center, Houston, Texas 77030, USA
    J Med Food 11:680-6. 2008
    ..Our study indicates that the mechanism of cardiac activity of hawthorn is via the Na(+),K(+)-ATPase and intracellular calcium concentrations are influenced...
  16. ncbi request reprint Interference of hawthorn on serum digoxin measurements by immunoassays and pharmacodynamic interaction with digoxin
    Amitava Dasgupta
    Department of Pathology and Laboratory Medicine, University of Texas Houston Medical School, Houston, TX 77030, USA
    Arch Pathol Lab Med 134:1188-92. 2010
    ..Hawthorn contains alkaloids that are structurally similar to digoxin and may interfere with serum digoxin measurement using immunoassays. In addition, hawthorn has cardioactive properties similar to digoxin...
  17. ncbi request reprint Ginseng: Cardiotonic in adult rat cardiomyocytes, cardiotoxic in neonatal rat cardiomyocytes
    Brian J Poindexter
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, MSB 2 288, 6431 Fannin Street, Houston, Texas 77030, USA
    Life Sci 79:2337-44. 2006
    ..However, for adults, ginseng might well be a 'tonic' in its ability to increase beating and intramyocytic calcium levels...
  18. ncbi request reprint Alterations in alpha adrenoreceptor density and localization after mechanical left ventricular unloading with the Jarvik flowmaker left ventricular assist device
    Alina Grigore
    Department of Cardiovascular Anesthesiology, Texas Heart Institute, Houston, Texas 77030, USA
    J Heart Lung Transplant 24:609-13. 2005
    ..Our previous work has demonstrated that the myocardium has the capacity to repair itself during a period of unloading, after which some patients are able to resume a normal lifestyle and no longer need a cardiac transplant...
  19. pmc Reversal of myocyte hypertrophy by ventricular unloading: cardiac improvement without adrenergic receptor up-regulation and relocalization
    Pippa M Schnee
    Department of Pathology, University of Texas Medical School at Houston, Texas, USA
    MedGenMed 8:45. 2006
    ..We suggest that interventions and strategies have to consider multiple, beneficial changes due to unloading and target a number of biochemical and structural areas to produce improvement, even if not all of these improvements occur...
  20. pmc Inflammatory cells and cytokines in the olfactory bulb of a rat model of neuroinflammation; insights into neurodegeneration?
    Marie Francoise Doursout
    Department of Anesthesiology, University of Texas Medical School at Houston, Houston, Texas 77030, USA
    J Interferon Cytokine Res 33:376-83. 2013
    ....
  21. ncbi request reprint Localization of antimicrobial peptides in normal and burned skin
    Brian J Poindexter
    The Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Burns 32:402-7. 2006
    ..The results of these studies further contribute to an understanding of the role of AMPs in the pathophysiology of cutaneous burn and the possibility of using these sites for upregulation of AMP synthesis in the prevention of burn sepsis...
  22. doi request reprint Left ventricular unloading before reperfusion reduces endothelin-1 release and calcium overload in porcine myocardial infarction
    Sophie Tamareille
    Division of Cardiovascular Medicine, University of Texas at Houston Medical School, Houston, TX 77030, USA
    J Thorac Cardiovasc Surg 136:343-51. 2008
    ..However, the biologic mechanisms of infarct salvage in unloaded hearts subjected to ischemia/reperfusion remain undefined...
  23. ncbi request reprint Effects of IgM from rheumatic fever patients on intracellular calcium levels of neonatal rat cardiac myocytes
    Roger J Bick
    Department of Pathology, University of Texas Health Science Center, 6431 Fannin Street, Houston, TX 77030, USA
    Life Sci 73:2101-11. 2003
    ..Treatment with both antibodies led to myocyte dysfunction and these novel findings suggest a role for antibodies in the pathogenesis of the myocarditis associated with rheumatic carditis...
  24. ncbi request reprint Effects of Chan Su, a traditional Chinese medicine, on the calcium transients of isolated cardiomyocytes: cardiotoxicity due to more than Na, K-ATPase blocking
    Roger J Bick
    Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, 6431 Fannin Street, 77030, USA
    Life Sci 72:699-709. 2002
    ....
  25. ncbi request reprint Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats
    Rosemary A Kozar
    Department of Surgery, University of Texas Houston School of Medicine, Houston, Texas 77030, USA
    Shock 21:433-7. 2004
    ..The individual components of enteral diets may differentially modulate intestinal barrier function, which could have important implications when administered to critically injured patients...
  26. ncbi request reprint Effects of cytokines and heat shock on defensin levels of cultured keratinocytes
    Roger J Bick
    The Department of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA
    Burns 30:329-33. 2004
    ..These experiments give us further insight into the role of natural antimicrobial peptides under conditions of stress...
  27. doi request reprint Reduced volume of the putamen in REM sleep behavior disorder patients
    Timothy M Ellmore
    Department of Neurosurgery, University of Texas Houston Medical School, MSB 7 044, 6431 Fannin St, Houston, TX 77030, USA
    Parkinsonism Relat Disord 16:645-9. 2010
    ..We hypothesized that REM sleep behavior disorder (RBD) patients, at risk for developing PD, will demonstrate a pattern of neuronal degeneration reflected in reduced striatal volumes on T1-weighted MRI...
  28. ncbi request reprint Expression of human beta defensin 2 in thermal injury
    Stephen M Milner
    Division of Plastic Surgery, The Institute for Plastic and Reconstructive Surgery, Southern Illinois University School of Medicine, P O Box 19653, 747 N Rutledge Street, Springfield, IL 62794 9653, USA
    Burns 30:649-54. 2004
    ....
  29. ncbi request reprint Cardiovascular distribution of the calcium sensing receptor before and after burns
    Gordon L Klein
    Department of Pediatrics, University of Texas Medical Branch Galveston, Galveston, TX, United States
    Burns 34:370-5. 2008
    ..We suggest that CaR has a local, tissue-specific role, and functions in vascular calcium sensing for intravascular calcium deposition or regulation of other calcium channels after trauma or burn...