Garry L Adams

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. ncbi Vaccination with attenuated Salmonella enterica Dublin expressing E coli O157:H7 outer membrane protein Intimin induces transient reduction of fecal shedding of E coli O157:H7 in cattle
    Sangeeta Khare
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 USA
    BMC Vet Res 6:35. 2010
  2. ncbi Diagnosis of foot-and mouth disease by real time reverse transcription polymerase chain reaction under field conditions in Brazil
    Tatiane A Paixao
    Departamento de Clínica e Cirurgia Veterinária, Escola de Veterinária da Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    BMC Vet Res 4:53. 2008
  3. ncbi A species independent universal bio-detection microarray for pathogen forensics and phylogenetic classification of unknown microorganisms
    Shamira J Shallom
    Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA, USA
    BMC Microbiol 11:132. 2011
  4. ncbi Brucella melitensis global gene expression study provides novel information on growth phase-specific gene regulation with potential insights for understanding Brucella:host initial interactions
    Carlos A Rossetti
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77483 4467, USA
    BMC Microbiol 9:81. 2009
  5. ncbi Enhancing the role of veterinary vaccines reducing zoonotic diseases of humans: linking systems biology with vaccine development
    L Garry Adams
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4467, USA
    Vaccine 29:7197-206. 2011
  6. ncbi Multi-comparative systems biology analysis reveals time-course biosignatures of in vivo bovine pathway responses to B.melitensis, S.enterica Typhimurium and M.avium paratuberculosis
    L Garry Adams
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4467, USA
    BMC Proc 5:S6. 2011
  7. ncbi Selective amplification of Brucella melitensis mRNA from a mixed host-pathogen total RNA
    Carlos A Rossetti
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX, USA
    BMC Res Notes 3:244. 2010
  8. ncbi The pathology of brucellosis reflects the outcome of the battle between the host genome and the Brucella genome
    L Garry Adams
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843 4467, USA
    Vet Microbiol 90:553-61. 2002
  9. ncbi Geostatistical analysis of biomarkers of genotoxicity in cattle, Bos taurus and Bos taurus x Bos indicus, sentinels near industrial facilities
    Wesley Bissett
    Department of Large Animal Clinical Sciences, Texas A and M University, 4475 TAMU, Mail Stop 4476, College Station, TX 77843 4475, USA
    Ecotoxicology 18:87-93. 2009
  10. ncbi Evaluation of novel Brucella melitensis unmarked deletion mutants for safety and efficacy in the goat model of brucellosis
    Melissa M Kahl-McDonagh
    Department of Veterinary Pathobiology, Texas A and M University and Texas Agricultural Experiment Station, College Station, TX 77843 4467, United States
    Vaccine 24:5169-77. 2006

Research Grants

  1. Veterinary Medical Student Research Training
    LESLIE ADAMS; Fiscal Year: 2007
  2. Veterinary Medical Student Research Training
    LESLIE GARRY ADAMS; Fiscal Year: 2010

Collaborators

  • Renee M Tsolis
  • Renato L Santos
  • Carlos A Rossetti
  • Sangeeta Khare
  • Harold Garner
  • Thomas A Ficht
  • Jenni N Weeks
  • Wesley Bissett
  • Christopher M Seabury
  • Irene R Grant
  • Roger Smith
  • H Morgan Scott
  • David McMurray
  • Steffen Porwollik
  • James Alan Thompson
  • M McClelland
  • Ferric Fang
  • LESLIE ADAMS
  • L Garry Adams
  • Sara D Lawhon
  • LESLIE GARRY ADAMS
  • Manuela Raffatellu
  • Shuping Zhang
  • Josely F Figueiredo
  • ANDREAS J BAUMLER
  • KENNETH L DRAKE
  • Harris A Lewin
  • Quynh T Tran
  • Mary S Lipton
  • Joshua E Turse
  • Yu Bai
  • Shamira J Shallom
  • Cristi L Galindo
  • Dennis C Wylie
  • Tatiane A Paixao
  • Melissa M Kahl-McDonagh
  • Andreas B den Hartigh
  • Helene L Andrews-Polymenis
  • Helene Andrews-Polymenis
  • Jairo Nunes
  • Wolf-Dietrich Hardt
  • José A Gutiérrez-Pabello
  • Yao Hui Sun
  • Tamara Gull
  • Jairo E S Nunes
  • Lauren McIver
  • John McCormick
  • Zhaohui Sun
  • Sarah A Luciano
  • Robin E Everts
  • George S Davidson
  • Dharani Ajithdoss
  • Soma Dhavala
  • Gabriel Gomez
  • Kuppan Gokulan
  • Robert C Burghardt
  • Beth A McCormick
  • Bernard Rousseau
  • Rola Barhoumi
  • Alcina V Carvalho Neta
  • Barbara M Martin
  • Tammy R Beckham
  • Naimes O Paiva
  • Jorge R Reis
  • Claudia V Serra
  • Neville P Clarke
  • Meirivan S Barbosa
  • René R Silva
  • Quinesha L Perry
  • Donald S Davis
  • Sue D Hagius
  • Philip H Elzer
  • Joel V Walker
  • Daniela Chessa
  • R Paul Wilson
  • Sara Lawhon
  • Wolfgang Rabsch
  • Carlos Rosetti
  • Robert A Kingsley
  • Josely Figueiredo
  • Susanne Mirold
  • Yao-Hui Sun
  • Silke Stender

Detail Information

Publications26

  1. ncbi Vaccination with attenuated Salmonella enterica Dublin expressing E coli O157:H7 outer membrane protein Intimin induces transient reduction of fecal shedding of E coli O157:H7 in cattle
    Sangeeta Khare
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 USA
    BMC Vet Res 6:35. 2010
    ..The present study was undertaken to test the hypothesis that an adaptive mucosal immune response directed against intimin will reduce or prevent enteric colonization and fecal shedding of E. coli O157:H7 in cattle...
  2. ncbi Diagnosis of foot-and mouth disease by real time reverse transcription polymerase chain reaction under field conditions in Brazil
    Tatiane A Paixao
    Departamento de Clínica e Cirurgia Veterinária, Escola de Veterinária da Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
    BMC Vet Res 4:53. 2008
    ..Virus isolation and enzyme-linked immunosorbent assay (ELISA) are the gold standard tests for diagnosis of FMD. As these methods are time consuming, assays based on viral nucleic acid amplification have been developed...
  3. ncbi A species independent universal bio-detection microarray for pathogen forensics and phylogenetic classification of unknown microorganisms
    Shamira J Shallom
    Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA, USA
    BMC Microbiol 11:132. 2011
    ..Given the enormous spectrum of genetic possibilities, a field deployable, robust technology, such as a universal (any species) microarray has near-term potential to address these needs...
  4. ncbi Brucella melitensis global gene expression study provides novel information on growth phase-specific gene regulation with potential insights for understanding Brucella:host initial interactions
    Carlos A Rossetti
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77483 4467, USA
    BMC Microbiol 9:81. 2009
    ..melitensis cultures to HeLa cells, as a preliminary approach for identifying candidate pathogen genes involved in invasion of epithelial cells...
  5. ncbi Enhancing the role of veterinary vaccines reducing zoonotic diseases of humans: linking systems biology with vaccine development
    L Garry Adams
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4467, USA
    Vaccine 29:7197-206. 2011
    ..Thus, we propose that such an approach has immediate application to the rational design of brucellosis and salmonellosis vaccines...
  6. ncbi Multi-comparative systems biology analysis reveals time-course biosignatures of in vivo bovine pathway responses to B.melitensis, S.enterica Typhimurium and M.avium paratuberculosis
    L Garry Adams
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4467, USA
    BMC Proc 5:S6. 2011
    ....
  7. ncbi Selective amplification of Brucella melitensis mRNA from a mixed host-pathogen total RNA
    Carlos A Rossetti
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX, USA
    BMC Res Notes 3:244. 2010
    ..The characterization of brucelae transcriptome's during host-pathogen interaction has been limited due to the difficulty of obtaining an adequate quantity of good quality eukaryotic RNA-free pathogen RNA for downstream applications...
  8. ncbi The pathology of brucellosis reflects the outcome of the battle between the host genome and the Brucella genome
    L Garry Adams
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843 4467, USA
    Vet Microbiol 90:553-61. 2002
    ..These discoveries will be expected to provide a frameshift in rationales for interrupting and/or controlling brucellosis at host and/or pathogen levels...
  9. ncbi Geostatistical analysis of biomarkers of genotoxicity in cattle, Bos taurus and Bos taurus x Bos indicus, sentinels near industrial facilities
    Wesley Bissett
    Department of Large Animal Clinical Sciences, Texas A and M University, 4475 TAMU, Mail Stop 4476, College Station, TX 77843 4475, USA
    Ecotoxicology 18:87-93. 2009
    ..Results indicated that proximity to and location down-prevailing winds from industrial facilities increased the locational risk of genotoxicity in this sentinel species...
  10. ncbi Evaluation of novel Brucella melitensis unmarked deletion mutants for safety and efficacy in the goat model of brucellosis
    Melissa M Kahl-McDonagh
    Department of Veterinary Pathobiology, Texas A and M University and Texas Agricultural Experiment Station, College Station, TX 77843 4467, United States
    Vaccine 24:5169-77. 2006
    ..Both strains were protective against abortion and against infection in the majority of pregnant goats, although BMDeltaasp24 was more efficacious than BMDeltavirB2 against challenge infection...
  11. ncbi Brucella melitensis VjbR and C12-HSL regulons: contributions of the N-dodecanoyl homoserine lactone signaling molecule and LuxR homologue VjbR to gene expression
    Jenni N Weeks
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843 4467, USA
    BMC Microbiol 10:167. 2010
    ..In an effort to further delineate the role of VjbR to virulence and survival, gene expression under the control of VjbR and AI was characterized using microarray analysis...
  12. ncbi Role of SPI-1 secreted effectors in acute bovine response to Salmonella enterica Serovar Typhimurium: a systems biology analysis approach
    Sara D Lawhon
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, Texas, United States of America
    PLoS ONE 6:e26869. 2011
    ....
  13. ncbi Salmonella serotype Typhimurium infection of bovine Peyer's patches down-regulates plasma membrane calcium-transporting ATPase expression
    Renato L Santos
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University System Health Science Center, College Station 77843 4467, USA
    J Infect Dis 186:372-8. 2002
    ....
  14. ncbi Molecular pathogenesis of Salmonella enterica serotype typhimurium-induced diarrhea
    Shuping Zhang
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, Texas 77843, USA
    Infect Immun 71:1-12. 2003
  15. ncbi Phage mediated horizontal transfer of the sopE1 gene increases enteropathogenicity of Salmonella enterica serotype Typhimurium for calves
    Shuping Zhang
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843-4467, USA
    FEMS Microbiol Lett 217:243-7. 2002
    ..Typhimurium in the bovine ligated ileal loop model. These data support the hypothesis that phage mediated horizontal transfer of the sopE1 gene contributes to the emergence of epidemic cattle-associated S. Typhimurium clones...
  16. ncbi The Salmonella enterica serotype Typhi Vi capsular antigen is expressed after the bacterium enters the ileal mucosa
    Quynh T Tran
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843 4467, USA
    Infect Immun 78:527-35. 2010
    ..Together, these results support the concept that expression of the Vi capsular antigen is induced when S. Typhi transits from the intestinal lumen into the ileal mucosa...
  17. ncbi Salmonella enterica serovar Typhimurium-induced internalization and IL-8 expression in HeLa cells does not have a direct relationship with intracellular Ca(2+) levels
    Josely F Figueiredo
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4467, USA
    Microbes Infect 11:850-8. 2009
    ....
  18. ncbi Secreted effector proteins of Salmonella enterica serotype typhimurium elicit host-specific chemokine profiles in animal models of typhoid fever and enterocolitis
    Shuping Zhang
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, Texas 77843-4467, USA
    Infect Immun 71:4795-803. 2003
    ..Thus, different disease outcomes between mice (i.e., no diarrhea) and calves (i.e., diarrhea) may be due to differences in sipA sopABDE2-dependent CXC chemokine gene expression in epithelial cells...
  19. ncbi Rapid and sensitive detection of Mycobacterium avium subsp. paratuberculosis in bovine milk and feces by a combination of immunomagnetic bead separation-conventional PCR and real-time PCR
    Sangeeta Khare
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, Texas 77843-4467, USA
    J Clin Microbiol 42:1075-81. 2004
    ....
  20. ncbi Host restriction of Salmonella enterica serotype Typhimurium pigeon isolates does not correlate with loss of discrete genes
    Helene L Andrews-Polymenis
    Department of Medical Microbiology and Immunology, College of Medicine, Texas A and M University System Health Science Center, College Station, TX 77843, USA
    J Bacteriol 186:2619-28. 2004
    ..We conclude that serotype Typhimurium phage types with broad host range do not possess genetic islands influencing host restriction, which are absent from the host-restricted pigeon isolates...
  21. ncbi Hematologic and serum biochemical changes in Salmonella ser Typhimurium-infected calves
    Renato L Santos
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station 77843-4467, USA
    Am J Vet Res 63:1145-50. 2002
    ....
  22. ncbi The Salmonella enterica serotype typhimurium effector proteins SipA, SopA, SopB, SopD, and SopE2 act in concert to induce diarrhea in calves
    Shuping Zhang
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, Texas 77843-4467, USA
    Infect Immun 70:3843-55. 2002
    ..These data demonstrate that SipA, SopA, SopB, SopD, and SopE2 are major virulence factors responsible for diarrhea during Salmonella serotype Typhimurium infection of calves...
  23. ncbi virB-Mediated survival of Brucella abortus in mice and macrophages is independent of a functional inducible nitric oxide synthase or NADPH oxidase in macrophages
    Yao Hui Sun
    Department of Medical Microbiology and Immunology, Texas A and M University System Health Science Center, College Station, USA
    Infect Immun 70:4826-32. 2002
    ..A virB mutant did not exhibit increased survival in either of the knockout mouse strains, indicating that this locus does not contribute to evasion of nitrosative or oxidative killing mechanisms in vivo...
  24. ncbi SipA, SopA, SopB, SopD, and SopE2 contribute to Salmonella enterica serotype typhimurium invasion of epithelial cells
    Manuela Raffatellu
    Department of Medical Microbiology and Immunology, College of Medicine, Texas A and M University System Health Science Center, 407 Reynolds Medical Building, College Station, TX 77843-1114, USA
    Infect Immun 73:146-54. 2005
    ..We conclude that SipA, SopA, SopB, SopD, and SopE2 contribute to S. enterica serotype Typhimurium invasion of epithelial cells in vitro...
  25. ncbi Salmonella enterica Typhimurium SipA induces CXC-chemokine expression through p38MAPK and JUN pathways
    Josely F Figueiredo
    Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843 4467, USA
    Microbes Infect 11:302-10. 2009
    ..These data indicate that S. typhimurium SipA induces expression of CXC chemokines through phosphorylation of IL-8-transcription regulatory proteins, JUN and p38MAK...
  26. ncbi Upregulation of thymosin beta-10 by Mycobacterium bovis infection of bovine macrophages is associated with apoptosis
    José A Gutiérrez-Pabello
    Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, Texas 77843, USA
    Infect Immun 70:2121-7. 2002
    ..01) and parental cells (P < 0.001). Our evidence suggests that upregulation of thymosin beta-10 in M. bovis-infected macrophages is linked with increased cell death due to apoptosis...

Research Grants6

  1. Veterinary Medical Student Research Training
    LESLIE ADAMS; Fiscal Year: 2007
    ..Our VMSRTP is squarely aimed at developing pre-doctoral veterinary into R01 level scientists for the future. ..
  2. Veterinary Medical Student Research Training
    LESLIE GARRY ADAMS; Fiscal Year: 2010
    ..The Veterinary Medical Student Research Training Program encourages veterinary students to enter research careers by immersing them in a focused 12-week program comprised of major aspects of a research career. ..