Paul Terasaki

Summary

Affiliation: Terasaki Foundation Laboratory
Country: USA

Publications

  1. ncbi request reprint Frequency of MIC antibody in rejected renal transplant patients without HLA antibody
    Kazuo Mizutani
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Hum Immunol 67:223-9. 2006
  2. doi request reprint Intact HLA not beta2m-free heavy chain-specific HLA class I antibodies are predictive of graft failure
    Junchao Cai
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Transplantation 88:226-30. 2009
  3. ncbi request reprint Four-year follow-up of a prospective trial of HLA and MICA antibodies on kidney graft survival
    P I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Am J Transplant 7:408-15. 2007
  4. doi request reprint Humoral theory of transplantation: some hot topics
    Junchao Cai
    Terasaki Foundation Laboratory, 11570 W Olympic Blvd, Los Angeles, CA 90064, USA
    Br Med Bull 105:139-55. 2013
  5. doi request reprint A personal perspective: 100-year history of the humoral theory of transplantation
    Paul I Terasaki
    Terasaki Foundation and UCLA Department of Surgery, UCLA School of Medicine, Los Angeles, CA 90064, USA
    Transplantation 93:751-6. 2012
  6. ncbi request reprint Predictive value of HLA antibodies and serum creatinine in chronic rejection: results of a 2-year prospective trial
    Paul I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Transplantation 80:1194-7. 2005
  7. ncbi request reprint Humoral theory of transplantation: further evidence
    Paul I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Curr Opin Immunol 17:541-5. 2005
  8. ncbi request reprint Antibody mediated rejection: update 2006
    Paul Terasaki
    Terasaki Foundation Laboratory, 11570 Olympic Blvd, Los Angeles, CA 90064, USA
    Clin J Am Soc Nephrol 1:400-3. 2006
  9. ncbi request reprint A brief history of HLA
    Paul I Terasaki
    Terasaki Foundation Laboratory, 11570 West Olympic Blvd, Los Angeles, CA 90064, USA
    Immunol Res 38:139-48. 2007
  10. ncbi request reprint Predicting kidney graft failure by HLA antibodies: a prospective trial
    Paul I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Am J Transplant 4:438-43. 2004

Detail Information

Publications38

  1. ncbi request reprint Frequency of MIC antibody in rejected renal transplant patients without HLA antibody
    Kazuo Mizutani
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Hum Immunol 67:223-9. 2006
    ..We conclude that antibodies to MIC are produced in the course of immunization by pregnancies and kidney transplants. They also occurred more frequently in rejected patients (30%) than in those with functioning grafts (21%)...
  2. doi request reprint Intact HLA not beta2m-free heavy chain-specific HLA class I antibodies are predictive of graft failure
    Junchao Cai
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Transplantation 88:226-30. 2009
    ..We investigated the effects of intact and beta2m-free heavy chain (HC)-specific human leukocyte antigen (HLA) class I antibodies on long-term graft survival...
  3. ncbi request reprint Four-year follow-up of a prospective trial of HLA and MICA antibodies on kidney graft survival
    P I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Am J Transplant 7:408-15. 2007
    ..0003) compared to 92% survival in those with no antibodies. In conclusion, these two prospective trials, after 1 and 4 years, provided strong evidence that HLA and MICA antibodies are associated with graft failure...
  4. doi request reprint Humoral theory of transplantation: some hot topics
    Junchao Cai
    Terasaki Foundation Laboratory, 11570 W Olympic Blvd, Los Angeles, CA 90064, USA
    Br Med Bull 105:139-55. 2013
    ..Antibody is a major cause of allograft injury. However, it has not been routinely tested post-transplant...
  5. doi request reprint A personal perspective: 100-year history of the humoral theory of transplantation
    Paul I Terasaki
    Terasaki Foundation and UCLA Department of Surgery, UCLA School of Medicine, Los Angeles, CA 90064, USA
    Transplantation 93:751-6. 2012
    ..Four studies have now shown that removal or reduction of antibodies result in higher graft survival. If removal of antibodies prevents chronic graft failure, final validation of the humoral theory can be achieved...
  6. ncbi request reprint Predictive value of HLA antibodies and serum creatinine in chronic rejection: results of a 2-year prospective trial
    Paul I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Transplantation 80:1194-7. 2005
    ..9 to 17.9%, and among those with 3.0-3.9 to 16.3%. We conclude that HLA antibodies posttransplantation is predictive of subsequent graft failure, and its predictive value can be enhanced among patients with higher serum creatinine values...
  7. ncbi request reprint Humoral theory of transplantation: further evidence
    Paul I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Curr Opin Immunol 17:541-5. 2005
    ..Together with serum creatinine, HLA antibodies are, therefore, the best predictor of graft function in kidney patients...
  8. ncbi request reprint Antibody mediated rejection: update 2006
    Paul Terasaki
    Terasaki Foundation Laboratory, 11570 Olympic Blvd, Los Angeles, CA 90064, USA
    Clin J Am Soc Nephrol 1:400-3. 2006
  9. ncbi request reprint A brief history of HLA
    Paul I Terasaki
    Terasaki Foundation Laboratory, 11570 West Olympic Blvd, Los Angeles, CA 90064, USA
    Immunol Res 38:139-48. 2007
  10. ncbi request reprint Predicting kidney graft failure by HLA antibodies: a prospective trial
    Paul I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Am J Transplant 4:438-43. 2004
    ..00003). Death occurred in 1.5% of patients and was not associated with antibodies. Thus, after 1 year in this prospective trial, patients with HLA antibodies had graft failure at a significantly higher rate than those without antibodies...
  11. ncbi request reprint Humoral theory of transplantation
    Paul I Terasaki
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Am J Transplant 3:665-73. 2003
    ..If successful, in patients who do not have antibodies, immunosuppression could be reduced until antibodies appear...
  12. ncbi request reprint Serial ten-year follow-up of HLA and MICA antibody production prior to kidney graft failure
    Kazuo Mizutani
    Terasaki Foundation Laboratory, Los Angeles, California, USA
    Am J Transplant 5:2265-72. 2005
    ..These antibodies found in the peripheral circulation, were not necessarily donor-specific, but their association with failure is consistent with a causality hypothesis...
  13. ncbi request reprint Association of kidney transplant failure and antibodies against MICA
    Kazuo Mizutani
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Hum Immunol 67:683-91. 2006
    ..001). We postulate that antibodies against HLA, MICA, endothelial cells, and B lymphoblasts could be independently involved in the slow process of chronic graft failure...
  14. ncbi request reprint Analysis of HLA class I specific antibodies in patients with failed allografts
    Quanzong Mao
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Transplantation 83:54-61. 2007
    ....
  15. doi request reprint "Natural" human leukocyte antigen antibodies found in nonalloimmunized healthy males
    Luis E Morales-Buenrostro
    Department of Nephrology and Mineral Metabolism, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, Mexico
    Transplantation 86:1111-5. 2008
    ..But with new methodology, we now see that HLA antibodies are often found in nonalloimmunized males...
  16. doi request reprint Mimetic human leukocyte antigen epitopes: shown by monoclonal antibodies and extra antibodies produced on transplantation
    Nori Sasaki
    One Lambda Incorporated, 21001 Kittridge Street, Canoga Park, CA, USA
    Transplantation 86:912-8. 2008
    ..The theory states that mimetic epitopes consist of the same three amino acids that comprise the primary, sterically placed approximately the same distance apart as are the corresponding amino acids of the primary...
  17. doi request reprint Human leukocyte antigen antibodies and chronic rejection: from association to causation
    Paul I Terasaki
    Transplantation 86:377-83. 2008
    ..The clinical implication is significant because we hope this review will stimulate centers to begin the one remaining task of showing that antibody removal will indeed prevent chronic failure...
  18. ncbi request reprint HLA class I epitopes: recognition of binding sites by mAbs or eluted alloantibody confirmed with single recombinant antigens
    Nadim El-Awar
    One Lambda Inc, Canoga Park, CA 90064, USA
    Hum Immunol 68:170-80. 2007
    ....
  19. ncbi request reprint Human leukocyte antigen class I epitopes: update to 103 total epitopes, including the C locus
    Nadim R El-Awar
    One Lambda Inc, Research II, 11570 W Olympic Boulevard, Los Angeles, CA 90064, USA
    Transplantation 84:532-40. 2007
    ..The use of monoclonal antibodies or alloantibodies eluted from HLA recombinant single antigen cell lines tested with a panel of single antigen beads have proved very useful in the identification of the epitopes...
  20. doi request reprint Human leukocyte antigen class II DQ alpha and beta epitopes identified from sera of kidney allograft recipients
    Chun Tsan Deng
    One Lambda Inc, Canoga Park, CA, USA
    Transplantation 86:452-9. 2008
    ..We can identify DQA1 and DQB1 epitopes by DQ single antigen beads assay of the antibodies, correlating the beads' reaction patterns with either DQA1 or DQB1 alleles...
  21. doi request reprint A single human leukocyte antigen-antibody test after heart or lung transplantation is predictive of survival
    Luis E Morales-Buenrostro
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Transplantation 85:478-81. 2008
    ..56% for those without (P<0.0001). These results indicate that for heart and lung transplant patients, a single test after transplantation of HLA antibodies is predictive of graft survival...
  22. ncbi request reprint Kidney graft and patient survival with and without a simultaneous pancreas utilizing contralateral kidneys from the same donor
    Kayo Waki
    Terasaki Foundation Laboratory, 11570 Olympic Blvd, Los Angeles, CA 90064, USA
    Diabetes Care 29:1670-2. 2006
  23. ncbi request reprint HIV-positive renal recipients can achieve survival rates similar to those of HIV-negative patients
    Jianxin Qiu
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Transplantation 81:1658-61. 2006
    ..To counteract suggestions that human immunodeficiency virus (HIV) patients received suboptimal kidneys, we provide studies of kidneys transplanted from the same donor into patients with and without HIV...
  24. ncbi request reprint All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies
    Po Chang Lee
    Department of Surgery, Medical College, University Hospital, National Cheng Kung University, 138 Sheng Li Road, Tainan, Taiwan 704
    Transplantation 74:1192-4. 2002
    ..Recent studies show that almost all patients who have rejected a kidney transplant had human leukocyte antigen (HLA) antibodies. In this study, we sought to determine whether patients develop HLA antibodies before chronic rejection...
  25. ncbi request reprint Single human leukocyte antigen flow cytometry beads for accurate identification of human leukocyte antigen antibody specificities
    Rui Pei
    Research Department, One Lambda Inc, Canoga Park, CA, USA
    Transplantation 75:43-9. 2003
    ..We describe here a single antigen bead panel for accurate identification of human leukocyte antigen (HLA) antibody specificities by flow cytometry...
  26. ncbi request reprint ABO mismatching errors in heart transplants
    Paul I Terasaki
    Lancet 362:332. 2003
  27. ncbi request reprint Correlation between human leukocyte antigen antibody production and serum creatinine in patients receiving sirolimus monotherapy after Campath-1H induction
    Junchao Cai
    Terasaki Foundation Laboratory, Los Angeles, California, USA
    Transplantation 78:919-24. 2004
    ..Second, we evaluated the correlation between human leukocyte antigen (HLA) antibody production and serum creatinine levels...
  28. ncbi request reprint Living-unrelated donors yield higher graft survival rates than parental donors
    Yasuro Futagawa
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Transplantation 79:1169-74. 2005
    ..Here, we show that in three diseases, LURDs supply grafts that survive at a higher rate than parental or offspring donors...
  29. ncbi request reprint Frequency and clinical implications of development of donor-specific and non-donor-specific HLA antibodies after kidney transplantation
    Maryvonne Hourmant
    Department of Nephrology and Clinical Immunology, Hotel Dieu, CHU de Nantes, Nantes Cedex, France
    J Am Soc Nephrol 16:2804-12. 2005
    ..Screening of HLA antibodies posttransplantation could be a good tool for the follow-up of patients who receive a kidney transplant and allow immunosuppression to be tailored...
  30. ncbi request reprint ABO incompatible kidney transplantation - an analysis of UNOS Registry data
    Yasuro Futagawa
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Clin Transplant 20:122-6. 2006
    ..However, there are few reports to support the feasibility of ABO incompatible transplants from non-A2 deceased donors. This problem was examined in the United Network for Organ Sharing (UNOS) data file...
  31. ncbi request reprint Detection of antibodies to HLA-DP in renal transplant recipients using single antigen beads
    Jianxin Qiu
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Transplantation 80:1511-3. 2005
    ..In conclusion, HLA-DP antibodies were detected at a higher frequency in patients who have rejected their grafts than those with functioning grafts. For regrafts, DP tissue typing is recommended to avoid presensitized DP alleles...
  32. ncbi request reprint Nomenclature for factors of the HLA system, 2002
    Steven G E Marsh
    Anthony Nolan Research Institute, Royal Free Hospital, Hampstead, London, UK
    Eur J Immunogenet 29:463-515. 2002
  33. ncbi request reprint Nomenclature for factors of the HLA system, 2002
    Steven G E Marsh
    Anthony Nolan Research Institute, Royal Free Hospital, Hampstead, London, United Kingdom
    Hum Immunol 63:1213-68. 2002
  34. ncbi request reprint Nomenclature for Factors of the HLA System, 2004
    Steven G E Marsh
    Anthony Nolan Research Institute, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, United Kingdom
    Hum Immunol 66:571-636. 2005
  35. ncbi request reprint Human leukocyte antigen antibodies for monitoring transplant patients
    Junchao Cai
    Terasaki Foundation Laboratory, 11570 West Olympic Boulevard, Los Angeles, CA, 90064, USA
    Surg Today 35:605-12. 2005
    ..We conclude that owing to the recent availability of improved antibody detection methods, a causal relationship between HLA antibodies and allograft rejection is now considered to exist...
  36. ncbi request reprint Humoral theory of transplantation: mechanism, prevention, and treatment
    Junchao Cai
    Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
    Hum Immunol 66:334-42. 2005
    ..It will help clinicians to determine a patient's humoral responses against allograft and will therefore direct clinicians to optimize and/or minimize immunosuppressive drug therapy...
  37. ncbi request reprint Paired kidney donation by shipment of living donor kidneys
    Kayo Waki
    Terasaki Foundation Laboratory, Los Angeles, CA, USA
    Clin Transplant 21:186-91. 2007
    ..After adjusting for major confounding factors, cold ischemia does not significantly influence graft survival. We conclude that shipment of donor kidneys can be performed safely and will significantly increase paired donor transplants...
  38. ncbi request reprint Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: impact of HLA class I antigen expression on outcome
    Jeffrey A Sosman
    Vanderbilt University, Nashville, TN, USA
    J Clin Oncol 20:2067-75. 2002
    ..This study investigated whether class I antigen expression impacted relapse-free survival (RFS) after adjuvant therapy with this vaccine...