Sara J Ward

Summary

Affiliation: Temple University
Country: USA

Publications

  1. ncbi Beta-funaltrexamine affects cocaine self-administration in rats responding on a progressive ratio schedule of reinforcement
    Sara Jane Ward
    Neuroscience Program, Wake Forest University, Winston-Salem, NC 27157, USA
    Pharmacol Biochem Behav 75:301-7. 2003
  2. ncbi Effect of cannabinoid CB1 receptor antagonist SR141716A and CB1 receptor knockout on cue-induced reinstatement of Ensure and corn-oil seeking in mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, Philadelphia, PA 19063, USA
    Neuropsychopharmacology 32:2592-600. 2007
  3. ncbi Microinjection of the delta-opioid receptor selective antagonist naltrindole 5'-isothiocyanate site specifically affects cocaine self-administration in rats responding under a progressive ratio schedule of reinforcement
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, 3307 North Broad Street, Philadelphia, PA 19140, USA
    Behav Brain Res 182:140-4. 2007
  4. ncbi Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, 3307 North Broad Street, Temple University School of Pharmacy, Philadelphia, PA 19140, USA
    J Pharmacol Exp Ther 325:567-76. 2008
  5. ncbi Age-dependent effects of the cannabinoid CB1 antagonist SR141716A on food intake, body weight change, and pruritus in rats
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19140, USA
    Psychopharmacology (Berl) 206:155-65. 2009
  6. ncbi The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse
    Sara Jane Ward
    Temple University School of Pharmacy, 3307 North Broad Street, Philadelphia, PA 19140, United States
    Drug Alcohol Depend 105:248-55. 2009
  7. ncbi Sex and cannabinoid CB1 genotype differentiate palatable food and cocaine self-administration behaviors in mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania, USA
    Behav Pharmacol 20:605-13. 2009
  8. ncbi Cannabidiol prevents the development of cold and mechanical allodynia in paclitaxel-treated female C57Bl6 mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania, USA
    Anesth Analg 113:947-50. 2011
  9. ncbi Comparison of the reinforcing effects of cocaine and cocaine/heroin combinations under progressive ratio and choice schedules in rats
    Sara Jane Ward
    Neuroscience Program, Wake Forest University School of Medicine, Winston-Salem, NC, USA
    Neuropsychopharmacology 30:286-95. 2005

Research Grants

  1. CB1 Receptors: Cocaine Reinforcement and Relapse
    Sara Ward; Fiscal Year: 2007

Detail Information

Publications9

  1. ncbi Beta-funaltrexamine affects cocaine self-administration in rats responding on a progressive ratio schedule of reinforcement
    Sara Jane Ward
    Neuroscience Program, Wake Forest University, Winston-Salem, NC 27157, USA
    Pharmacol Biochem Behav 75:301-7. 2003
    ..The present findings suggest that endogenous opiate systems within the mesolimbic DA system modulate the reinforcing effects of cocaine; however, this modulation seems to be schedule dependent...
  2. ncbi Effect of cannabinoid CB1 receptor antagonist SR141716A and CB1 receptor knockout on cue-induced reinstatement of Ensure and corn-oil seeking in mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, Philadelphia, PA 19063, USA
    Neuropsychopharmacology 32:2592-600. 2007
    ..This and other possible reasons for the observed discrepancy between pharmacological blockade vs genetic invalidation of the CB1 receptor on reinstatement of Ensure seeking are discussed...
  3. ncbi Microinjection of the delta-opioid receptor selective antagonist naltrindole 5'-isothiocyanate site specifically affects cocaine self-administration in rats responding under a progressive ratio schedule of reinforcement
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, 3307 North Broad Street, Philadelphia, PA 19140, USA
    Behav Brain Res 182:140-4. 2007
    ..5'-NTII administration into the AMYG produced no effect. These data support a site-specific role of DORs in cocaine's behavioral effects...
  4. ncbi Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, 3307 North Broad Street, Temple University School of Pharmacy, Philadelphia, PA 19140, USA
    J Pharmacol Exp Ther 325:567-76. 2008
    ....
  5. ncbi Age-dependent effects of the cannabinoid CB1 antagonist SR141716A on food intake, body weight change, and pruritus in rats
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA 19140, USA
    Psychopharmacology (Berl) 206:155-65. 2009
    ..Although childhood obesity is a rising health issue, it is unknown whether SR141716A is equipotent at modulating food intake and other CB1-mediated behaviors in younger subjects...
  6. ncbi The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse
    Sara Jane Ward
    Temple University School of Pharmacy, 3307 North Broad Street, Philadelphia, PA 19140, United States
    Drug Alcohol Depend 105:248-55. 2009
    ....
  7. ncbi Sex and cannabinoid CB1 genotype differentiate palatable food and cocaine self-administration behaviors in mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania, USA
    Behav Pharmacol 20:605-13. 2009
    ..The present data add to a small but growing literature suggesting that the cannabinoid system may be differentially sensitive in its modulation of appetitive behavior in males versus females...
  8. ncbi Cannabidiol prevents the development of cold and mechanical allodynia in paclitaxel-treated female C57Bl6 mice
    Sara Jane Ward
    Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania, USA
    Anesth Analg 113:947-50. 2011
    ..Our preliminary findings therefore indicate that cannabidiol may prevent the development of paclitaxel-induced allodynia in mice and therefore be effective at preventing dose-limiting paclitaxel-induced peripheral neuropathy in humans...
  9. ncbi Comparison of the reinforcing effects of cocaine and cocaine/heroin combinations under progressive ratio and choice schedules in rats
    Sara Jane Ward
    Neuroscience Program, Wake Forest University School of Medicine, Winston-Salem, NC, USA
    Neuropsychopharmacology 30:286-95. 2005
    ..These apparently discrepant results demonstrate that these models are measuring different aspects of drug reinforcement, and suggest that choice procedures in rats provide a useful tool to study speedball self-administration...

Research Grants1

  1. CB1 Receptors: Cocaine Reinforcement and Relapse
    Sara Ward; Fiscal Year: 2007
    ..The second goal is to employ this set of procedures to assess the role of the CB1 receptor system in cocaine's reinforcing effects and relapse to cocaine seeking. ..