Yoshiya Toyoda

Summary

Affiliation: Temple University
Country: USA

Publications

  1. ncbi request reprint Present status and future perspectives of heart transplantation
    Yoshiya Toyoda
    Division of Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Circ J 77:1097-110. 2013
  2. doi request reprint Efficacy of extracorporeal membrane oxygenation as a bridge to lung transplantation
    Yoshiya Toyoda
    University of Pittsburgh, Pittsburgh, PA, USA
    J Thorac Cardiovasc Surg 145:1065-70; discussion 1070-1. 2013
  3. doi request reprint Cadaveric donor lobar lung transplantation for patients on extracorporeal membrane oxygenation as bridge-to-transplant
    Yoshiya Toyoda
    Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Gen Thorac Cardiovasc Surg 61:197-200. 2013
  4. doi request reprint Lung transplantation for patients with high lung allocation score: single-center experience
    Tetsuya Horai
    Division of Cardiothoracic Transplantation, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 93:1592-7; discussion 1597. 2012
  5. doi request reprint Histidine-tryptophan-ketoglutarate or celsior: which is more suitable for cold preservation for cardiac grafts from older donors?
    Sungsoo Lee
    Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Ann Thorac Surg 91:755-63. 2011
  6. doi request reprint Cytomegalovirus disease among donor-positive/recipient-negative lung transplant recipients in the era of valganciclovir prophylaxis
    Dimitra Mitsani
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Heart Lung Transplant 29:1014-20. 2010
  7. pmc Prospective, observational study of voriconazole therapeutic drug monitoring among lung transplant recipients receiving prophylaxis: factors impacting levels of and associations between serum troughs, efficacy, and toxicity
    Dimitra Mitsani
    Divisions of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Antimicrob Agents Chemother 56:2371-7. 2012
  8. doi request reprint Voriconazole exposure and geographic location are independent risk factors for squamous cell carcinoma of the skin among lung transplant recipients
    Aniket Vadnerkar
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    J Heart Lung Transplant 29:1240-4. 2010
  9. doi request reprint Impact of extracorporeal membrane oxygenation or mechanical ventilation as bridge to combined heart-lung transplantation on short-term and long-term survival
    Senthil N Jayarajan
    1 Department of Surgery, Temple University School of Medicine, Philadelphia, PA 2 College of Health Professions and Social Work, Temple University, Philadelphia, PA 3 Section of Cardiothoracic Surgery, Department of Surgery, Temple University School of Medicine, Philadelphia, PA 4 Section of Pulmonology and Critical Care, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 5 Address correspondence to Yoshiya Toyoda, M D, Temple University Hospital, Third Floor, Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140
    Transplantation 97:111-5. 2014
  10. doi request reprint Preservation solution supplemented with biliverdin prevents lung cold ischaemia/reperfusion injury
    Ryujiro Sugimoto
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Eur J Cardiothorac Surg 42:1035-41. 2012

Detail Information

Publications68

  1. ncbi request reprint Present status and future perspectives of heart transplantation
    Yoshiya Toyoda
    Division of Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Circ J 77:1097-110. 2013
    ..Therefore, significant efforts have been made to maximize the number of heart transplants and to ensure good outcomes.  ..
  2. doi request reprint Efficacy of extracorporeal membrane oxygenation as a bridge to lung transplantation
    Yoshiya Toyoda
    University of Pittsburgh, Pittsburgh, PA, USA
    J Thorac Cardiovasc Surg 145:1065-70; discussion 1070-1. 2013
    ..The purpose of this study is to determine whether ECMO as a bridge to lung transplantation is an acceptable option to support those in respiratory failure until donor lungs become available in the lung allocation score era...
  3. doi request reprint Cadaveric donor lobar lung transplantation for patients on extracorporeal membrane oxygenation as bridge-to-transplant
    Yoshiya Toyoda
    Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Gen Thorac Cardiovasc Surg 61:197-200. 2013
    ..With recent advances in extracorporeal membrane oxygenation (ECMO) technology and surgical experience, ECMO has been used before, during and after lung transplant surgery successfully...
  4. doi request reprint Lung transplantation for patients with high lung allocation score: single-center experience
    Tetsuya Horai
    Division of Cardiothoracic Transplantation, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 93:1592-7; discussion 1597. 2012
    ..This study is a review of a single institutional experience for lung transplantation in the era of LAS...
  5. doi request reprint Histidine-tryptophan-ketoglutarate or celsior: which is more suitable for cold preservation for cardiac grafts from older donors?
    Sungsoo Lee
    Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Ann Thorac Surg 91:755-63. 2011
    ....
  6. doi request reprint Cytomegalovirus disease among donor-positive/recipient-negative lung transplant recipients in the era of valganciclovir prophylaxis
    Dimitra Mitsani
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Heart Lung Transplant 29:1014-20. 2010
    ..Valganciclovir prophylaxis is advocated for lung transplant recipients, but its efficacy is unknown...
  7. pmc Prospective, observational study of voriconazole therapeutic drug monitoring among lung transplant recipients receiving prophylaxis: factors impacting levels of and associations between serum troughs, efficacy, and toxicity
    Dimitra Mitsani
    Divisions of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Antimicrob Agents Chemother 56:2371-7. 2012
    ..Voriconazole prophylaxis was most effective at troughs of >1.5 μg/ml. A cutoff for toxicity was not identified, but troughs of >4 μg/ml were rare. The data support a target range of >1.5 to 4 μg/ml...
  8. doi request reprint Voriconazole exposure and geographic location are independent risk factors for squamous cell carcinoma of the skin among lung transplant recipients
    Aniket Vadnerkar
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, USA
    J Heart Lung Transplant 29:1240-4. 2010
    ..SCC has been reported in immunosuppressed patients receiving voriconazole, but the agent has not been shown to be a risk factor. Universal voriconazole prophylaxis and alemtuzumab induction are standard in our lung transplant program...
  9. doi request reprint Impact of extracorporeal membrane oxygenation or mechanical ventilation as bridge to combined heart-lung transplantation on short-term and long-term survival
    Senthil N Jayarajan
    1 Department of Surgery, Temple University School of Medicine, Philadelphia, PA 2 College of Health Professions and Social Work, Temple University, Philadelphia, PA 3 Section of Cardiothoracic Surgery, Department of Surgery, Temple University School of Medicine, Philadelphia, PA 4 Section of Pulmonology and Critical Care, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 5 Address correspondence to Yoshiya Toyoda, M D, Temple University Hospital, Third Floor, Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140
    Transplantation 97:111-5. 2014
    ..Extracorporeal membrane oxygenation (ECMO) and mechanical ventilation (MV) can be used as a bridge to heart-lung transplantation (HLT). The goal of this study was to determine if pretransplantation ECMO or MV affects survival in HLT...
  10. doi request reprint Preservation solution supplemented with biliverdin prevents lung cold ischaemia/reperfusion injury
    Ryujiro Sugimoto
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Eur J Cardiothorac Surg 42:1035-41. 2012
    ..We hypothesized that adding BV to the perfusate and cold storage solution could protect rat lung grafts from oxidative injuries via its antioxidant efficacies...
  11. doi request reprint Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration
    Kentaro Noda
    Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Transpl Int 25:1213-22. 2012
    ..Drinking HW prolongs survival of cardiac allografts and reduces intimal hyperplasia of aortic allografts...
  12. doi request reprint Extracorporeal membrane oxygenation as a bridge to lung transplant: midterm outcomes
    Christian A Bermudez
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Ann Thorac Surg 92:1226-31; discussion 1231-2. 2011
    ..The impact on mid-term survival is unknown. We analyzed outcomes after lung transplant over a 19-year period in patients who received ECMO support...
  13. doi request reprint Donor smoking history and age in lung transplantation: a revisit
    Norihisa Shigemura
    Division of Cardiothoracic Transplantation, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Transplantation 95:513-8. 2013
    ..Because we experienced unexpected adverse outcomes after transplant of lungs from teenaged donors with no smoking history, this study revisited the effects of donor smoking history in relation to age on transplant outcomes...
  14. doi request reprint Double-lung transplantation can be safely performed using donors with heavy smoking history
    Sharven Taghavi
    Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    Ann Thorac Surg 95:1912-7; discussion 1917-8. 2013
    ..We attempt to determine if adult, double-lung transplantation can be safely performed with lungs from heavy-smoking donors (HSD)...
  15. doi request reprint Combining tricuspid valve repair with double lung transplantation in patients with severe pulmonary hypertension, tricuspid regurgitation, and right ventricular dysfunction
    Norihisa Shigemura
    Division of Cardiothoracic Transplantation, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Chest 140:1033-9. 2011
    ..This study is a review of that single institutional experience...
  16. doi request reprint A polymorphism linked to elevated levels of interferon-γ is associated with an increased risk of cytomegalovirus disease among Caucasian lung transplant recipients at a single center
    Dimitra Mitsani
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Heart Lung Transplant 30:523-9. 2011
    ..Single-nucleotide polymorphisms (SNPs) associated with active cytomegalovirus (CMV) infections after lung transplantation have not been identified...
  17. doi request reprint Heart transplantation for adults with congenital heart disease: results in the modern era
    Jay K Bhama
    Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Heart Lung Transplant 32:499-504. 2013
    ..The purpose of this study was to evaluate survival outcomes after heart transplantation in a contemporary cohort of adults with CHD and to identify risk factors for mortality that may help guide recipient and donor selection...
  18. doi request reprint Staphylococcus aureus infections in the early period after lung transplantation: epidemiology, risk factors, and outcomes
    Ryan K Shields
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    J Heart Lung Transplant 31:1199-206. 2012
    ..Staphylococcus aureus infections among lung transplant recipients are poorly studied...
  19. pmc Invasive aspergillosis among heart transplant recipients is rare but causes rapid death due to septic shock and multiple organ dysfunction syndrome
    Ryan K Shields
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Scand J Infect Dis 44:982-6. 2012
    ....
  20. pmc Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats
    Qiang Sun
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Cardiovasc Res 94:144-53. 2012
    ..Hydrogen potently protects organs and cells from many insults via its anti-inflammatory and antioxidant properties. We investigated the efficacy of oral administration of hydrogen-rich water (HW) for prevention of intimal hyperplasia...
  21. doi request reprint Impact of renal function before mechanical circulatory support on posttransplant renal outcomes
    Madhurmeet Singh
    Cardiovascular Institute, Department of Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 91:1348-54. 2011
    ..Mechanical circulatory support frequently improves renal function, but the impact of pre-MCS renal dysfunction on renal function after cardiac transplantation (CTX) is unknown...
  22. pmc Five-year outcomes with alemtuzumab induction after lung transplantation
    Susan Shyu
    Department of Medicine, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Heart Lung Transplant 30:743-54. 2011
    ....
  23. doi request reprint Age-specific complications among lung transplant recipients 60 years and older
    Aniket Vadnerkar
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Heart Lung Transplant 30:273-81. 2011
    ..An age limit of 65 years has been suggested for lung transplantation (LTx)...
  24. doi request reprint Superior myocardial preservation with HTK solution over Celsior in rat hearts with prolonged cold ischemia
    Sungsoo Lee
    The Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Surgery 148:463-73. 2010
    ..The purpose of this study was to evaluate the protective effects of histidine-tryptophan-ketoglutarate (HTK) and Celsior (CEL) using a rat HTx model with prolonged cold storage...
  25. doi request reprint Hydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation
    Bettina M Buchholz
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Transplantation 92:985-92. 2011
    ..Inhaled hydrogen gas exerts antioxidant and anti-inflammatory effects in rat intestinal transplantation. Here, we investigated whether ex vivo donor organ treatment with dissolved hydrogen would prevent intestinal graft injury...
  26. doi request reprint Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement
    Yugo Tanaka
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Biochem Biophys Res Commun 425:873-9. 2012
    ..To elucidate the mechanisms underlying hydrogen's protective effects, we conducted a gene array analysis to identify changes in gene expression associated with hydrogen treatment...
  27. pmc Posaconazole serum concentrations among cardiothoracic transplant recipients: factors impacting trough levels and correlation with clinical response to therapy
    Ryan K Shields
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Antimicrob Agents Chemother 55:1308-11. 2011
    ..5 μg/ml were more likely to have successful outcome (P = 0.055). Age ≥ 65 years, oral administration, and absence of proton pump inhibitors were associated with higher levels of posaconazole (P = 0.006, 0.006, and 0.001, respectively)...
  28. doi request reprint The effect of donor treatment with hydrogen on lung allograft function in rats
    Tomohiro Kawamura
    Department of Surgery, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Surgery 150:240-9. 2011
    ....
  29. doi request reprint Impact of graft volume reduction for oversized grafts after lung transplantation on outcome in recipients with end-stage restrictive pulmonary diseases
    Norihisa Shigemura
    Division of Cardiopulmonary Transplantation, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Heart Lung Transplant 28:130-4. 2009
    ..Although graft volume reduction (GVR) is useful to overcome related disparities, its merits and demerits remain unclear...
  30. pmc Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo
    Tomohiro Kawamura
    Division of Cardiothoracic Transplantation, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Physiol Lung Cell Mol Physiol 304:L646-56. 2013
    ..The findings suggest a potentially novel and applicable solution to hyperoxic lung injury and provide new insight into the molecular mechanisms and actions of hydrogen...
  31. pmc Ex vivo carbon monoxide delivery inhibits intimal hyperplasia in arterialized vein grafts
    Atsunori Nakao
    Department of Surgery, University of Pittsburgh Medical Center, E1551, Biomedical Science Tower, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Cardiovasc Res 89:457-63. 2011
    ..We investigated the feasibility and efficacy of the ex vivo pre-treatment of vein grafts with soluble carbon monoxide (CO) in the inhibition of IH...
  32. doi request reprint Lung transplant, double valve repair, and pulmonary artery aneurysm resection
    Hossein Shayan
    Heart, Lung and Esophageal Surgery Institute, Division of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 93:e3-5. 2012
    ..We report a case of combined mitral and pulmonary valve repair, resection of a giant pulmonary artery aneurysm, and double lung transplant in a patient with primary pulmonary hypertension...
  33. pmc Hydrogen inhalation ameliorates ventilator-induced lung injury
    Chien Sheng Huang
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Crit Care 14:R234. 2010
    ..Inhaled hydrogen can act as an antioxidant and may be useful as a novel therapeutic gas. We hypothesized that, owing to its antioxidant and anti-inflammatory properties, inhaled hydrogen therapy could ameliorate VILI...
  34. pmc Pulsatile left ventricular assist device support as a bridge to decision in patients with end-stage heart failure complicated by pulmonary hypertension
    Pradeep K Nair
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Heart Lung Transplant 29:201-8. 2010
    ..Left ventricular assist devices (LVADs) improve pulmonary hemodynamics, but our understanding of the degree of improvement and the effect on outcomes is still evolving...
  35. doi request reprint Impact of abdominal complications on outcome after mechanical circulatory support
    Jay K Bhama
    Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 89:522-8; discussion 528-9. 2010
    ..Most devices require abdominal wall transgression, creating a potential for abdominal complications. The incidence and impact of these relatively underreported complications are unknown...
  36. doi request reprint Ganciclovir-resistant cytomegalovirus infections among lung transplant recipients are associated with poor outcomes despite treatment with foscarnet-containing regimens
    Lucio R Minces
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Antimicrob Agents Chemother 58:128-35. 2014
    ..Foscarnet-based regimens often eradicated viremia rapidly but were ineffective in the long term and limited by toxicity. ..
  37. doi request reprint Lobar lung transplantation: a relevant surgical option in the current era of lung allocation score
    Norihisa Shigemura
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 96:451-6. 2013
    ..Here, we review our experience using cadaveric lobar lung transplantation as a surgical option in an attempt to decrease mortality while waiting...
  38. doi request reprint Extracorporeal membrane oxygenation for advanced refractory shock in acute and chronic cardiomyopathy
    Christian A Bermudez
    Department of Cardiothoracic Surgery, Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 92:2125-31. 2011
    ....
  39. doi request reprint Long-term effects on renal function of dose-reduced calcineurin inhibitor and sirolimus in cardiac transplant patients
    Sameer J Khandhar
    Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Clin Transplant 26:42-9. 2012
    ..This study examines the long-term effects of such a strategy...
  40. doi request reprint Midterm surgical outcomes of noncomplicated active native multivalve endocarditis: single-center experience
    Takeyoshi Ota
    Department of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 91:1414-9. 2011
    ..Surgical treatment for endocarditis is still challenging and only a handful of studies have analyzed surgical outcomes in patients with active multivalvular endocarditis...
  41. doi request reprint Antireflux surgery preserves lung function in patients with gastroesophageal reflux disease and end-stage lung disease before and after lung transplantation
    Toshitaka Hoppo
    Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA 15232, USA
    Arch Surg 146:1041-7. 2011
    ..GERD may cause obliterative bronchiolitis after lung transplantation (LTx), represented by a decline in forced expiratory volume in 1 second (FEV(1))...
  42. doi request reprint Surgical revascularization for cardiac allograft vasculopathy: Is it still an option?
    Jay K Bhama
    Division of Cardiothoracic Transplantation, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Thorac Cardiovasc Surg 137:1488-92. 2009
    ..Outcomes following surgical revascularization are evaluated to determine whether surgery remains a viable therapeutic option...
  43. doi request reprint Pitfalls in donor lung procurements: how should the procedure be taught to transplant trainees?
    Norihisa Shigemura
    Cardiopulmonary Transplantation, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Thorac Cardiovasc Surg 138:486-90. 2009
    ..Few reports, however, have provided recommendations for successful lung procurement procedures...
  44. doi request reprint Surgical outcomes after cardiac surgery in liver transplant recipients
    Takeyoshi Ota
    Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Thorac Cardiovasc Surg 145:1072-6. 2013
    ..This was a single-center retrospective study to assess the surgical outcomes and predictors of mortality of liver transplant recipients undergoing cardiac surgery...
  45. doi request reprint Comparison of an Aspergillus real-time polymerase chain reaction assay with galactomannan testing of bronchoalvelolar lavage fluid for the diagnosis of invasive pulmonary aspergillosis in lung transplant recipients
    Me Linh Luong
    Department of Medicine, University of Pittsburgh, Pennsylvania, 15261, USA
    Clin Infect Dis 52:1218-26. 2011
    ..Early diagnosis and treatment of invasive pulmonary aspergillosis (IPA) improves outcome...
  46. pmc Impact of mold infections in explanted lungs on outcomes of lung transplantation
    Aniket Vadnerkar
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15251, USA
    Transplantation 89:253-60. 2010
    ..Little is known about the incidence or significance of mold infections in the explanted lungs of lung transplant recipients...
  47. doi request reprint Obese patients and mechanical circulatory support: weight loss, adverse events, and outcomes
    Firas Zahr
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Thorac Surg 92:1420-6. 2011
    ..Obesity and heart failure are increasingly common, but the outcomes, weight changes, and adverse events of patients with advanced heart failure and obesity on mechanical support is not well described...
  48. pmc A micro-ribonucleic acid signature associated with recovery from assist device support in 2 groups of patients with severe heart failure
    Ravi Ramani
    Heart and Vascular Institute, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Am Coll Cardiol 58:2270-8. 2011
    ....
  49. doi request reprint Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats
    Tomohiro Kawamura
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Transplantation 90:1344-51. 2010
    ..The purpose of this research was to investigate whether inhaled hydrogen gas could reduce graft I/R injury during lung transplantation...
  50. doi request reprint Long-term outcome of lung and heart-lung transplantation for idiopathic pulmonary arterial hypertension
    Yoshiya Toyoda
    Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 86:1116-22. 2008
    ..The survival after lung and heart-lung transplantation for idiopathic pulmonary arterial hypertension has been reportedly the lowest among the major diagnostic categories of lung transplant recipients...
  51. doi request reprint Single-lung transplantation can be performed with acceptable outcomes using selected donors with heavy smoking history
    Sharven Taghavi
    Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania
    J Heart Lung Transplant 32:1005-12. 2013
    ..We attempt to determine if adult, single-lung transplantation could be performed with acceptable results in heavy-smoking donors (HSDs; > 20 pack-years)...
  52. doi request reprint Portopulmonary hypertension as an indication for combined heart, lung, and liver or lung and liver transplantation: literature review and case presentation
    Nicole E Scouras
    Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Liver Transpl 17:137-43. 2011
    ..CHLLT should be considered for patients with refractory PPHTN. The assessment of preoperative cardiac function is a vital part of the decision to include heart transplantation in CLLT...
  53. doi request reprint Adenosine injection prior to cardioplegia enhances preservation of senescent hearts in rat heterotopic heart transplantation
    Sang Hyun Lim
    Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Eur J Cardiothorac Surg 43:1202-8. 2013
    ..The purpose of this study was to determine if adenosine, which is known to enhance cardioplegic protection, enhances myocardial preservation during heart transplantation using older donors...
  54. doi request reprint Extracorporeal membrane oxygenation for primary graft dysfunction after lung transplantation: long-term survival
    Christian A Bermudez
    Division of Cardiothoracic Surgery, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Ann Thorac Surg 87:854-60. 2009
    ..We analyzed outcomes after ECMO use for PGD after lung transplantation at a single center over a 15-year period and assessed long-term survival...
  55. pmc Onset and risk factors for anxiety and depression during the first 2 years after lung transplantation
    Mary Amanda Dew
    Department of Psychiatry, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, PA 15213, USA
    Gen Hosp Psychiatry 34:127-38. 2012
    ..We sought to provide the first prospective data on rates and risk factors for anxiety disorders as well as depressive disorders during the first 2 years after transplantation...
  56. doi request reprint Midterm outcomes of off-pump and on-pump coronary artery revascularization in renal transplant recipients
    Hossein Shayan
    Department of Cardiothoracic Surgery, Thomas E Starzl Transplantation Institute, and Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Card Surg 26:591-5. 2011
    ..This study was undertaken to evaluate outcomes of on-pump versus off-pump revascularization in renal transplant recipients...
  57. pmc Left ventricular remodeling and myocardial recovery on mechanical circulatory support
    Marc A Simon
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA, USA
    J Card Fail 16:99-105. 2010
    ..Myocardial recovery after ventricular assist devices (VAD) is rare but appears more common in nonischemic cardiomyopathies (NICM). We sought to evaluate left ventricular (LV) end diastolic diameter (LVEDD) for predicting recovery after VAD...
  58. doi request reprint High mortality rates among solid organ transplant recipients infected with extensively drug-resistant Acinetobacter baumannii: using in vitro antibiotic combination testing to identify the combination of a carbapenem and colistin as an effective treatment
    Ryan K Shields
    University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Diagn Microbiol Infect Dis 70:246-52. 2011
    ..Subsequently, 80% (4/5) of transplant patients were treated successfully with carbepenem-colistin regimens...
  59. pmc Sternal-sparing approach for reoperative bilateral lung transplantation
    Jay K Bhama
    Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Interact Cardiovasc Thorac Surg 17:835-7. 2013
    ..A sternal-sparing approach for bilateral lung transplantation was recently applied to reoperative lung transplant cases and is compared with the traditional clamshell approach...
  60. doi request reprint Anti-human leukocyte antigen antibodies, vascular C4d deposition and increased soluble c4d in broncho-alveolar lavage of lung allografts
    Alin L Girnita
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 86:342-7. 2008
    ..A simultaneous determination of vascular C4d with soluble C4d in broncho-alveolar lavage fluid (BAL) and circulating anti-human leukocyte antigen (HLA) antibodies (HLA-Ab) has not been reported in lung transplantation...
  61. ncbi request reprint Application of carbon monoxide for transplantation
    Atsunori Nakao
    Thomas E Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh, PA, USA
    Curr Pharm Biotechnol 13:827-36. 2012
    ..In addition, we will discuss the clinical applicability of CO as a promising therapeutic strategy for the treatment of transplant patients...
  62. doi request reprint Initial experience with single cannulation for venovenous extracorporeal oxygenation in adults
    Christian A Bermudez
    Heart, Lung, and Esophageal Surgery Institute, Pittsburgh, Pennsylvania, USA
    Ann Thorac Surg 90:991-5. 2010
    ..A single-venous cannulation strategy may facilitate implantation and patient mobilization. Here we present our early experience with a single cannulation technique...
  63. doi request reprint Successful conservative management of blunt right ventricular rupture in a patient with prior cardiac surgery
    Takeyoshi Ota
    Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Interact Cardiovasc Thorac Surg 13:686-7. 2011
    ..We experienced a rare case of blunt right ventricular disruption that was successfully managed by conservative therapy without surgery...
  64. doi request reprint Clinical experience using the Levitronix CentriMag system for temporary right ventricular mechanical circulatory support
    Jay K Bhama
    Division of Cardiac Surgery, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Heart Lung Transplant 28:971-6. 2009
    ..This study evaluates our clinical experience using the CentriMag (Levitronix LLC, Waltham, Mass) system for temporary mechanical RV support...
  65. pmc Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors
    Ki Mun Kang
    Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Med Gas Res 1:11. 2011
    ..abstract:..
  66. doi request reprint Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both
    Atsunori Nakao
    Department of Surgery, Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittburgh, Pennsylvania 15213, USA
    J Heart Lung Transplant 29:544-53. 2010
    ..This study was designed to evaluate the effects of inhaled hydrogen or CO, or both, on cold ischemia/reperfusion (I/R) injury of the myocardium...
  67. pmc Immunosuppression decreases inflammation and increases AAV6-hSERCA2a-mediated SERCA2a expression
    Xiaodong Zhu
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hum Gene Ther 23:722-32. 2012
    ..However, the hSERCA2a protein level is reduced by host immune responses. Immunosuppression alleviates immune responses and sustains transgene expression, and may be an important adjuvant for clinical gene therapy trials...
  68. doi request reprint Combined heart and liver transplantation in a patient with situs ambiguous
    Tetsuya Horai
    Division of Cardiothoracic Transplantation, Heart, Lung, and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Thorac Surg 91:600-1. 2011
    ..Combined simultaneous heart and liver transplantation was successfully performed with technical modifications, including rotated implantation and bilateral venous reconstruction...