Cristiano Simone

Summary

Affiliation: Temple University
Country: USA

Publications

  1. ncbi request reprint A homozygous frameshift mutation in the ESCO2 gene: evidence of intertissue and interindividual variation in Nmd efficiency
    Nicoletta Resta
    Dipartimento di Biomedicina dell Eta Evolutiva, Sezione di Genetica Medica, Universita di Bari, Italy
    J Cell Physiol 209:67-73. 2006
  2. ncbi request reprint SWI/SNF: the crossroads where extracellular signaling pathways meet chromatin
    Cristiano Simone
    Department of Biomedicine in Childhood, Division of Medical Genetics, University of Bari, Bari, Italy
    J Cell Physiol 207:309-14. 2006
  3. ncbi request reprint Signal-dependent control of autophagy and cell death in colorectal cancer cell: the role of the p38 pathway
    Cristiano Simone
    Division of Medical Genetics, Department of Biomedicine in Childhood, University of Bari, Bari, Italy
    Autophagy 3:468-71. 2007
  4. ncbi request reprint Identification of murine cdk10: association with Ets2 transcription factor and effects on the cell cycle
    Luigi Bagella
    Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia, Pennsylvania 19122, USA
    J Cell Biochem 99:978-85. 2006
  5. ncbi request reprint p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
    Cristiano Simone
    Laboratory of Gene Expression, Dulbecco Telethon Institute at Fondazione A Cesalpino, Institute of Cell Biology and Tissue Engineering, San Raffaele Biomedical Science Park of Rome, Rome 00128, Italy
    Nat Genet 36:738-43. 2004
  6. pmc Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation
    Carlo Serra
    The Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037 1062, USA
    Mol Cell 28:200-13. 2007
  7. ncbi request reprint MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions
    Cristina Giacinti
    Department of Biology, Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology Temple University, Philadelphia, Pennsylvania 19122, USA
    J Cell Physiol 206:807-13. 2006
  8. ncbi request reprint Activation of MyoD-dependent transcription by cdk9/cyclin T2
    Cristiano Simone
    Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, Philadelphia, Pennsylvania, PA 19122, USA
    Oncogene 21:4137-48. 2002
  9. doi request reprint Signal-dependent regulation of gene expression as a target for cancer treatment: inhibiting p38alpha in colorectal tumors
    Fulvio Chiacchiera
    Laboratory of Signal dependent Transcription, Department of Translational Pharmacology DTP, Consorzio Mario Negri Sud, Via Nazionale 8 A, 66030 Santa Maria Imbaro Chieti, Italy
    Cancer Lett 265:16-26. 2008
  10. ncbi request reprint Porous silicon surfaces: a candidate substrate for reverse protein arrays in cancer biomarker detection
    Anton Ressine
    Department of Electrical Measurement, Lund University, Lund, Sweden
    Electrophoresis 28:4407-15. 2007

Collaborators

  • Antonio Giordano
  • Jiri Bartek
  • Po Zhao
  • Antonio De Luca
  • Cristina Giacinti
  • Luigi Bagella
  • Pier Lorenzo Puri
  • Irina Corin
  • Ginevra Guanti
  • Carlo Serra
  • Fulvio Chiacchiera
  • Anton Ressine
  • Nicoletta Resta
  • Rosanna Bagnulo
  • Marilena C Di Giacomo
  • Simona Iezzi
  • Lucia Latella
  • Isabelle Jourdan
  • Giulia De Falco
  • Mario Molinaro
  • Antonio Musaro
  • David R Jones
  • Kerstin Jaras
  • Keyong Du
  • Daniela Palacios
  • Chiara Mozzetta
  • Gyorgy Marko-Varga
  • Meri Ripani
  • Ulupi S Jhala
  • Sonia V Forcales
  • Thomas Laurell
  • Ianessa Morantte
  • Patrizia Lastella
  • Nenad Bukvic
  • Francesco Claudio Susca
  • Alessandro Stella
  • Monica Di Padova
  • Eric P Hoffman
  • Jiri Lukas
  • Eric Maklan
  • Giuseppina Caretti
  • Giulia Minetti
  • Vittorio Sartorelli

Detail Information

Publications15

  1. ncbi request reprint A homozygous frameshift mutation in the ESCO2 gene: evidence of intertissue and interindividual variation in Nmd efficiency
    Nicoletta Resta
    Dipartimento di Biomedicina dell Eta Evolutiva, Sezione di Genetica Medica, Universita di Bari, Italy
    J Cell Physiol 209:67-73. 2006
    ....
  2. ncbi request reprint SWI/SNF: the crossroads where extracellular signaling pathways meet chromatin
    Cristiano Simone
    Department of Biomedicine in Childhood, Division of Medical Genetics, University of Bari, Bari, Italy
    J Cell Physiol 207:309-14. 2006
    ..The SWI/SNF chromatin remodeling complex offers the ideal surface for integrating these signals in the execution of diverse or even opposite biological programs...
  3. ncbi request reprint Signal-dependent control of autophagy and cell death in colorectal cancer cell: the role of the p38 pathway
    Cristiano Simone
    Division of Medical Genetics, Department of Biomedicine in Childhood, University of Bari, Bari, Italy
    Autophagy 3:468-71. 2007
    ....
  4. ncbi request reprint Identification of murine cdk10: association with Ets2 transcription factor and effects on the cell cycle
    Luigi Bagella
    Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia, Pennsylvania 19122, USA
    J Cell Biochem 99:978-85. 2006
    ..Murine cdk10 binds Ets2 transcription factors in vitro, does not show a direct involvement in the G2/M transition and, therefore, does not affect the proliferation rate of the cell lines analyzed...
  5. ncbi request reprint p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
    Cristiano Simone
    Laboratory of Gene Expression, Dulbecco Telethon Institute at Fondazione A Cesalpino, Institute of Cell Biology and Tissue Engineering, San Raffaele Biomedical Science Park of Rome, Rome 00128, Italy
    Nat Genet 36:738-43. 2004
    ..These results identify an unexpected function of differentiation-activated p38 in converting external cues into chromatin modifications at discrete loci, by selectively targeting SWI-SNF to muscle-regulatory elements...
  6. pmc Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation
    Carlo Serra
    The Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037 1062, USA
    Mol Cell 28:200-13. 2007
    ....
  7. ncbi request reprint MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions
    Cristina Giacinti
    Department of Biology, Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology Temple University, Philadelphia, Pennsylvania 19122, USA
    J Cell Physiol 206:807-13. 2006
    ....
  8. ncbi request reprint Activation of MyoD-dependent transcription by cdk9/cyclin T2
    Cristiano Simone
    Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, Philadelphia, Pennsylvania, PA 19122, USA
    Oncogene 21:4137-48. 2002
    ..Finally, cdk9 can phosphorylate MyoD in vitro, suggesting the possibility that cdk9/cycT2a regulation of muscle differentiation includes the direct enzymatic activity of the kinase on MyoD...
  9. doi request reprint Signal-dependent regulation of gene expression as a target for cancer treatment: inhibiting p38alpha in colorectal tumors
    Fulvio Chiacchiera
    Laboratory of Signal dependent Transcription, Department of Translational Pharmacology DTP, Consorzio Mario Negri Sud, Via Nazionale 8 A, 66030 Santa Maria Imbaro Chieti, Italy
    Cancer Lett 265:16-26. 2008
    ..In this review we will focus on the possibility to inhibit p38alpha in colorectal cancer to arrest tumor progression and induce autophagic cell death...
  10. ncbi request reprint Porous silicon surfaces: a candidate substrate for reverse protein arrays in cancer biomarker detection
    Anton Ressine
    Department of Electrical Measurement, Lund University, Lund, Sweden
    Electrophoresis 28:4407-15. 2007
    ..The data demonstrate the potential use of macroporous silicon as a substrate for quantitative determination of a cancer biomarker cyclin E in tissue lysates...
  11. ncbi request reprint Tumor-specific hyperactive low-molecular-weight cyclin E isoforms detection and characterization in non-metastatic colorectal tumors
    Irina Corin
    Department of Oncology, Sahlgrenska Hospital, Gothenburg University, Gothenburg, Sweden
    Cancer Biol Ther 5:198-203. 2006
    ..We investigated the status of cyclin E and p53 in cell lines and tissue samples of colorectal cancer, one of the leading causes of death from a tumor in the Western world...
  12. pmc Differentiation-induced radioresistance in muscle cells
    Lucia Latella
    Institute of Cancer Biology, Danish Cancer Society, Copenhagen, Denmark
    Mol Cell Biol 24:6350-61. 2004
    ....
  13. ncbi request reprint Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin
    Simona Iezzi
    Muscle Gene Expression Group, Laboratory of Muscle Biology, NIAMS, National Institutes of Health, Bethesda, MD 20892, USA
    Dev Cell 6:673-84. 2004
    ....
  14. ncbi request reprint Physical interaction between pRb and cdk9/cyclinT2 complex
    Cristiano Simone
    Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, PA 19107, USA
    Oncogene 21:4158-65. 2002
    ....
  15. doi request reprint Cdk9-55: a new player in muscle regeneration
    Cristina Giacinti
    Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, USA
    J Cell Physiol 216:576-82. 2008
    ..This alternative form is specifically induced in injured myofibers and its activity is strictly required for the completion of muscle regeneration process...