YURI contact PERSIDSKY

Summary

Affiliation: Temple University
Country: USA

Publications

  1. ncbi Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists
    Servio H Ramirez
    1 Temple University School of Medicine, 3401 N Broad St, Philadelphia, PA 19140, USA or
    J Leukoc Biol 93:801-10. 2013
  2. ncbi Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages
    Jieliang Li
    Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    J Neuroinflammation 8:15. 2011
  3. ncbi HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions
    Yuri Persidsky
    Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Brain Behav Immun 25:S61-70. 2011

Research Grants

  1. Alcohol Abuse and HIV-1: Mechanisms of Combined CNS Injury and Interventions
    Yuri Persidsky; Fiscal Year: 2009
  2. Mechanisms and Interventions for Methamphetamine and HIV-1 Induced CNS Injury
    Yuri Persidsky; Fiscal Year: 2009
  3. PPAR-gamma-mediated neuroprotection against HIV-1 and alcohol CNS injury
    Yuri Persidsky; Fiscal Year: 2009
  4. Mechanisms and Interventions for Methamphetamine and HIV-1 Induced CNS Injury
    YURI contact PERSIDSKY; Fiscal Year: 2010
  5. BBB Protection in HIV-1 Dementia: Anti-Inflammatory effects of GSK-3beta suppres
    Yuri Persidsky; Fiscal Year: 2010
  6. Alcohol Abuse and HIV-1: Mechanisms of Combined CNS Injury and Interventions
    YURI contact PERSIDSKY; Fiscal Year: 2010
  7. BBB Tight Junctions During HIV-1 dementia
    Yuri Persidsky; Fiscal Year: 2006
  8. BBB Protection in HIV-1 Dementia: Anti-Inflammatory effects of GSK-3beta suppres
    Yuri Persidsky; Fiscal Year: 2007
  9. Alcohol Abuse and HIV-1: Mechanisms of Combined CNS Injury and Interventions
    Yuri Persidsky; Fiscal Year: 2009

Collaborators

  • Servio H Ramirez
  • Xu Wang
  • Wen Zhe Ho
  • Jieliang Li
  • Nancy L Reichenbach
  • Slava Rom
  • Steven F Merkel
  • Shongshan Fan
  • Dennis L Kolson
  • Li Ye
  • Jinping Liu
  • Denise R Cook

Detail Information

Publications3

  1. ncbi Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists
    Servio H Ramirez
    1 Temple University School of Medicine, 3401 N Broad St, Philadelphia, PA 19140, USA or
    J Leukoc Biol 93:801-10. 2013
    ..Results from a single-round infection with the pseudotyped virus revealed a marked decrease in HIV-1 LTR activation by the CB2 ligands. Together, these results indicate that CB2 may offer a means to limit HIV-1 infection in macrophages...
  2. ncbi Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages
    Jieliang Li
    Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    J Neuroinflammation 8:15. 2011
    ..In this study, we examined whether BBI has the ability to inhibit LPS-mediated macrophage activation, reducing the release of pro-inflammatory cytokines and subsequent neurotoxicity in primary cortical neural cultures...
  3. ncbi HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions
    Yuri Persidsky
    Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Brain Behav Immun 25:S61-70. 2011
    ..Agonists of cannabinoid receptor 2 (CB₂) possess potent anti-inflammatory and neuroprotective properties. We address multifaceted beneficial effects of CB₂ activation in the setting of HIV-1 brain infection and alcohol abuse...

Research Grants21

  1. Alcohol Abuse and HIV-1: Mechanisms of Combined CNS Injury and Interventions
    Yuri Persidsky; Fiscal Year: 2009
    ..Current proposal aims to understand mechanisms of combined effects of HIV-1 and alcohol abuse in the brain and to propose neuroprotective therapies. ..
  2. Mechanisms and Interventions for Methamphetamine and HIV-1 Induced CNS Injury
    Yuri Persidsky; Fiscal Year: 2009
    ..Current proposal aims to understand mechanisms of combined effects of HIV-1 and methamphetamine in the brain and to propose neuroprotective therapies. ..
  3. PPAR-gamma-mediated neuroprotection against HIV-1 and alcohol CNS injury
    Yuri Persidsky; Fiscal Year: 2009
    ..The availability of PPARgamma agonists approved for clinical use will permit rapid translation of experimental findings into therapeutic applications. ..
  4. Mechanisms and Interventions for Methamphetamine and HIV-1 Induced CNS Injury
    YURI contact PERSIDSKY; Fiscal Year: 2010
    ..Current proposal aims to understand mechanisms of combined effects of HIV-1 and methamphetamine in the brain and to propose neuroprotective therapies. ..
  5. BBB Protection in HIV-1 Dementia: Anti-Inflammatory effects of GSK-3beta suppres
    Yuri Persidsky; Fiscal Year: 2010
    ....
  6. Alcohol Abuse and HIV-1: Mechanisms of Combined CNS Injury and Interventions
    YURI contact PERSIDSKY; Fiscal Year: 2010
    ..Current proposal aims to understand mechanisms of combined effects of HIV-1 and alcohol abuse in the brain and to propose neuroprotective therapies. ..
  7. BBB Tight Junctions During HIV-1 dementia
    Yuri Persidsky; Fiscal Year: 2006
    ..These will provide clues about how TJ integrity may be manipulated pharmacologically. Such studies should have broad relevance in the pathogenesis of a wide range of neurodegenerative disorders. ..
  8. BBB Protection in HIV-1 Dementia: Anti-Inflammatory effects of GSK-3beta suppres
    Yuri Persidsky; Fiscal Year: 2007
    ....
  9. Alcohol Abuse and HIV-1: Mechanisms of Combined CNS Injury and Interventions
    Yuri Persidsky; Fiscal Year: 2009
    ..Current proposal aims to understand mechanisms of combined effects of HIV-1 and alcohol abuse in the brain and to propose neuroprotective therapies. ..