Weimin Kong

Summary

Affiliation: Temple University
Country: USA

Publications

  1. pmc Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family
    Weimin Kong
    Department of Microbiology and Immunology, Temple University School of Medicine, 3500 North Broad Street, Philadelphia, Pennsylvania 19140, USA
    Lipids Health Dis 9:12. 2010
  2. pmc Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs
    Miguel G Toscano
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    Mol Ther 18:1035-45. 2010
  3. pmc Docosahexaenoic acid prevents dendritic cell maturation, inhibits antigen-specific Th1/Th17 differentiation and suppresses experimental autoimmune encephalomyelitis
    Weimin Kong
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Brain Behav Immun 25:872-82. 2011
  4. pmc Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1
    Kirsten M Hooper
    Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140
    J Immunol . 2017
  5. pmc Selective CB2 receptor activation ameliorates EAE by reducing Th17 differentiation and immune cell accumulation in the CNS
    Weimin Kong
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, United States
    Cell Immunol 287:1-17. 2014
  6. pmc Differential effects of IFN-β on IL-12, IL-23, and IL-10 expression in TLR-stimulated dendritic cells
    Jui Hung Yen
    Department of Microbiology and Immunology, Indiana University School of Medicine, Fort Wayne, Indiana, USA Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    J Leukoc Biol 98:689-702. 2015
  7. pmc IFN-beta inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9
    Jui Hung Yen
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA
    J Immunol 184:3478-86. 2010
  8. doi request reprint The natural dual cyclooxygenase and 5-lipoxygenase inhibitor flavocoxid is protective in EAE through effects on Th1/Th17 differentiation and macrophage/microglia activation
    Weimin Kong
    Department of Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA
    Brain Behav Immun 53:59-71. 2016

Collaborators

Detail Information

Publications8

  1. pmc Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family
    Weimin Kong
    Department of Microbiology and Immunology, Temple University School of Medicine, 3500 North Broad Street, Philadelphia, Pennsylvania 19140, USA
    Lipids Health Dis 9:12. 2010
    ....
  2. pmc Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs
    Miguel G Toscano
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    Mol Ther 18:1035-45. 2010
    ....
  3. pmc Docosahexaenoic acid prevents dendritic cell maturation, inhibits antigen-specific Th1/Th17 differentiation and suppresses experimental autoimmune encephalomyelitis
    Weimin Kong
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Brain Behav Immun 25:872-82. 2011
    ..Similar to the in vitro results, the beneficial effect of DHA in EAE was associated with reduced numbers of IFNγ- and IL-17-producing CD4(+) T cells in both spleen and CNS...
  4. pmc Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1
    Kirsten M Hooper
    Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140
    J Immunol . 2017
    ....
  5. pmc Selective CB2 receptor activation ameliorates EAE by reducing Th17 differentiation and immune cell accumulation in the CNS
    Weimin Kong
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, United States
    Cell Immunol 287:1-17. 2014
    ..In addition, the combined effect on Th17 differentiation and immune cell accumulation into the CNS, emphasize the relevance of CB2 selective ligands as potential therapeutic agents in neuroinflammation. ..
  6. pmc Differential effects of IFN-β on IL-12, IL-23, and IL-10 expression in TLR-stimulated dendritic cells
    Jui Hung Yen
    Department of Microbiology and Immunology, Indiana University School of Medicine, Fort Wayne, Indiana, USA Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    J Leukoc Biol 98:689-702. 2015
    ..However, neither IRF mediated the effects of IFN-β on IL-12, IL-23, or IL-10. We found that the PI3K pathway mediated IL-12 inhibition but did not interfere with the inhibition of IL-23 or stimulation of IL-10. ..
  7. pmc IFN-beta inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9
    Jui Hung Yen
    Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA 19140, USA
    J Immunol 184:3478-86. 2010
    ..The suppression of mature DC migration through negative regulation of CCR7 and MMP-9 expression represents a novel mechanism for the therapeutic effect of IFN-beta...
  8. doi request reprint The natural dual cyclooxygenase and 5-lipoxygenase inhibitor flavocoxid is protective in EAE through effects on Th1/Th17 differentiation and macrophage/microglia activation
    Weimin Kong
    Department of Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA
    Brain Behav Immun 53:59-71. 2016
    ..As a dual COX/5-LO inhibitor with antioxidant properties, flavocoxid might be useful as a potential therapeutic medical food agent in MS patients. ..