Howard J Eisen

Summary

Affiliation: Temple University
Country: USA

Publications

  1. ncbi request reprint Immunosuppression on the horizon
    Howard J Eisen
    Drexel University College of Medicine, Philadelphia, PA 19102, USA
    Heart Fail Clin 3:43-9. 2007
  2. ncbi request reprint Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients
    Howard J Eisen
    Section of Cardiology, Temple University, Philadelphia, PA 19140, USA
    N Engl J Med 349:847-58. 2003
  3. ncbi request reprint Three-year results of a randomized, double-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac transplant recipients
    Howard J Eisen
    Division of Cardiology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102 1192, USA
    J Heart Lung Transplant 24:517-25. 2005
  4. ncbi request reprint Effect of older donor age on risk for mortality after heart transplantation
    Dipin Gupta
    Division of Cardiac and Thoracic Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Ann Thorac Surg 78:890-9. 2004
  5. ncbi request reprint Early growth responsive gene (Egr)-1 expression correlates with cardiac allograft rejection
    Michael V Autieri
    Department of Physiology, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Transplantation 78:107-11. 2004
  6. doi request reprint Raman spectroscopy detects cardiac allograft rejection with molecular specificity
    Yoon Gi Chung
    Drexel University, Philadelphia, Pennsylvania 19104, USA
    Clin Transl Sci 2:206-10. 2009
  7. ncbi request reprint Expression of the FAST-1 transcription factor in coronary artery transplant vasculopathy and activated vascular smooth muscle cells
    Sheri F Kelemen
    Department of Cardiology, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    J Heart Lung Transplant 24:246-50. 2005
  8. ncbi request reprint Cardiac transplantation across a positive prospective lymphocyte cross-match in sensitized recipients
    Stephen H Leech
    Departments of Pathology and Laboratory Medicine, Temple University Hospital and School of Medicine, Philadelphia, PA, USA
    Clin Transplant 17:17-26. 2003
  9. ncbi request reprint Factors affecting survival after heart transplantation: comparison of pre- and post-1999 listing protocols
    Alfred A Bove
    Section of Cardiology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    J Heart Lung Transplant 25:42-7. 2006
  10. doi request reprint Serum 25-hydroxyvitamin D concentration and mortality from heart failure and cardiovascular disease, and premature mortality from all-cause in United States adults
    Longjian Liu
    Department of Epidemiology and Biostatistics, Drexel University School of Public Health, Philadelphia, PA, USA
    Am J Cardiol 110:834-9. 2012

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Immunosuppression on the horizon
    Howard J Eisen
    Drexel University College of Medicine, Philadelphia, PA 19102, USA
    Heart Fail Clin 3:43-9. 2007
    ..Finally, costimulatory pathway inhibitors and other new immunosuppressive agents offer hope that all these goals can be accomplished with very low long-term maintenance immunosuppression...
  2. ncbi request reprint Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients
    Howard J Eisen
    Section of Cardiology, Temple University, Philadelphia, PA 19140, USA
    N Engl J Med 349:847-58. 2003
    ..We conducted a randomized, double-blind, clinical trial comparing everolimus with azathioprine in recipients of a first heart transplant...
  3. ncbi request reprint Three-year results of a randomized, double-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac transplant recipients
    Howard J Eisen
    Division of Cardiology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102 1192, USA
    J Heart Lung Transplant 24:517-25. 2005
    ..This study reports the 36-month results of a randomized, double-blind, active-controlled trial of mycophenolate mofetil (MMF) vs azathioprine (AZA) in heart transplant patients...
  4. ncbi request reprint Effect of older donor age on risk for mortality after heart transplantation
    Dipin Gupta
    Division of Cardiac and Thoracic Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Ann Thorac Surg 78:890-9. 2004
    ..Our goal was to determine if older donor age is associated with an increased risk of mortality and specifically if the use of donor hearts at least 50 years of age reduces survival...
  5. ncbi request reprint Early growth responsive gene (Egr)-1 expression correlates with cardiac allograft rejection
    Michael V Autieri
    Department of Physiology, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Transplantation 78:107-11. 2004
    ..The goal of this work is to determine whether Egr-1 expression could be used as a surrogate marker of cardiac allograft rejection...
  6. doi request reprint Raman spectroscopy detects cardiac allograft rejection with molecular specificity
    Yoon Gi Chung
    Drexel University, Philadelphia, Pennsylvania 19104, USA
    Clin Transl Sci 2:206-10. 2009
    ....
  7. ncbi request reprint Expression of the FAST-1 transcription factor in coronary artery transplant vasculopathy and activated vascular smooth muscle cells
    Sheri F Kelemen
    Department of Cardiology, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    J Heart Lung Transplant 24:246-50. 2005
    ..Identification of genes expressed in activated VSMCs may provide clues to the pathogenesis and progression of cardiac allograft vasculopathy (CAV)...
  8. ncbi request reprint Cardiac transplantation across a positive prospective lymphocyte cross-match in sensitized recipients
    Stephen H Leech
    Departments of Pathology and Laboratory Medicine, Temple University Hospital and School of Medicine, Philadelphia, PA, USA
    Clin Transplant 17:17-26. 2003
    ..The reason for undertaking the current study was to test the hypothesis that the constraints which a positive LCM result impose in preventing renal transplantation may not apply to orthotopic heart transplantation (OHT)...
  9. ncbi request reprint Factors affecting survival after heart transplantation: comparison of pre- and post-1999 listing protocols
    Alfred A Bove
    Section of Cardiology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    J Heart Lung Transplant 25:42-7. 2006
    ..Because the selection process was modified in favor of seriously ill patients, it was not clear whether this change would affect survival or other aspects of transplant management...
  10. doi request reprint Serum 25-hydroxyvitamin D concentration and mortality from heart failure and cardiovascular disease, and premature mortality from all-cause in United States adults
    Longjian Liu
    Department of Epidemiology and Biostatistics, Drexel University School of Public Health, Philadelphia, PA, USA
    Am J Cardiol 110:834-9. 2012
    ..001, test for trend). In conclusion, adults with inadequate serum 25(OH)D levels have significantly higher risk of death from HF and all CVDs and all-cause premature death...
  11. ncbi request reprint Allograft inflammatory factor-1 expression correlates with cardiac rejection and development of cardiac allograft vasculopathy
    Michael V Autieri
    Department of Physiology, Cardiovascular Research Group, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Circulation 106:2218-23. 2002
    ....
  12. doi request reprint Clinical utility of intravascular ultrasound in the assessment of coronary allograft vasculopathy: a review
    Sachin Logani
    Drexel University College of Medicine, Philadelphia, Pennsylvania, USA
    J Interv Cardiol 24:9-14. 2011
    ..After reviewing the relevant published literature, it is our recommendation that the use of IVUS be considered in all post-transplant CAV screening...
  13. doi request reprint Ethical considerations for ventricular assist device support: a 10-point model
    Ralph J Petrucci
    Department of Psychiatry, Drexel University College of Medicine Hahnemann University Hospital, Philadelphia, Pennsylvania 19102, USA
    ASAIO J 57:268-73. 2011
    ..This three-phase 10-point model addresses the ethical and psychosocial issues that should be discussed with patients undergoing VAD support...
  14. ncbi request reprint Hypertension in heart transplant recipients: more than just cyclosporine
    Howard J Eisen
    J Am Coll Cardiol 41:433-4. 2003
  15. doi request reprint Clinical implications and longitudinal alteration of peripheral blood transcriptional signals indicative of future cardiac allograft rejection
    Mandeep R Mehra
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Heart Lung Transplant 27:297-301. 2008
    ..We have previously demonstrated that a peripheral blood transcriptional profile using 11 distinct genes predicts onset of cardiac allograft rejection weeks to months prior to the actual event...
  16. ncbi request reprint Transcriptional signals of T-cell and corticosteroid-sensitive genes are associated with future acute cellular rejection in cardiac allografts
    Mandeep R Mehra
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Heart Lung Transplant 26:1255-63. 2007
    ..Profiling mRNA levels of 11 informative genes expressed by circulating immune effector cells identifies cardiac allograft recipients at low risk for current moderate-severe acute cellular rejection (ACR)...
  17. ncbi request reprint Adverse outcomes from the use of older donor hearts in cardiac transplant recipients: the pros and cons of expanded donor criteria
    Howard J Eisen
    J Am Coll Cardiol 43:1562-4. 2004
  18. ncbi request reprint Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: a 24-month analysis
    Mario Vigano
    Department of Cardiac Surgery, San Matteo Hospital, Pavia, Italy
    J Heart Lung Transplant 26:584-92. 2007
    ..Everolimus is an immunosuppressive agent that reduces cardiac allograft vasculopathy. This report presents the 24-month results of a multicenter trial of everolimus vs azathioprine in heart transplantation...
  19. ncbi request reprint Daclizumab to prevent rejection after cardiac transplantation
    Ray E Hershberger
    Department of Medicine Cardiology, UHN 62, Oregon Health and Science University, Portland, OR 97239, USA
    N Engl J Med 352:2705-13. 2005
    ..We conducted a multicenter, placebo-controlled, double-blind study to confirm these results in cardiac-transplant patients...
  20. ncbi request reprint The economic implications of noninvasive molecular testing for cardiac allograft rejection
    Roger W Evans
    Am J Transplant 5:1553-8. 2005
    ....
  21. ncbi request reprint Statin use and risks of death or fatal rejection in the Heart Transplant Lipid Registry
    Audrey H Wu
    Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA
    Am J Cardiol 95:367-72. 2005
    ..Statin therapy was significantly associated with lower risk of death and fatal rejection, benefits that were independent of lipid values...
  22. ncbi request reprint Similar efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS, myfortic) compared with mycophenolate mofetil (MMF) in de novo heart transplant recipients: results of a 12-month, single-blind, randomized, parallel-group, multicenter study
    Jon A Kobashigawa
    Department of Cardiology, University of California at Los Angeles, Los Angeles, California 90095, USA
    J Heart Lung Transplant 25:935-41. 2006
    ..Enteric-coated mycophenolate sodium (EC-MPS, myfortic) is an advanced formulation that delays the release of mycophenolic acid (MPA). Its efficacy and safety has been proven in several clinical trials in renal transplantation...
  23. ncbi request reprint Heart allograft rejection: detection with breath alkanes in low levels (the HARDBALL study)
    Michael Phillips
    Menssana Research, Inc Fort Lee, New Jersey, USA
    J Heart Lung Transplant 23:701-8. 2004
    ..Rejection is accompanied by oxidative stress that degrades membrane polyunsaturated fatty acids, evolving alkanes and methylalkanes, which are excreted in the breath as volatile organic compounds (VOCs)...
  24. ncbi request reprint Safety and feasibility of autologous myoblast transplantation in patients with ischemic cardiomyopathy: four-year follow-up
    Nabil Dib
    Arizona Heart Institute, Phoenix, AZ 85006, USA
    Circulation 112:1748-55. 2005
    ..In addition, we sought to gain preliminary information on graft survival and any associated changes in cardiac function...
  25. doi request reprint Exercise training and myocardial energetics in patients with heart failure: when more is less
    Howard J Eisen
    J Am Coll Cardiol 51:1892-5. 2008
  26. ncbi request reprint Prediction of heart transplant rejection with a breath test for markers of oxidative stress
    Michael Phillips
    Menssana Research Inc, Fort Lee, New Jersey, USA
    Am J Cardiol 94:1593-4. 2004
    ..98, and 100% specific when the p value was </=0.058; in the intermediate group, the breath test determined the probability of grade 3 rejection and the predictive value of the result...
  27. ncbi request reprint Feasibility and safety of autologous myoblast transplantation in patients with ischemic cardiomyopathy
    Nabil Dib
    Arizona Heart Institute, 2632 N 20th Street, Phoenix, AZ 85006, USA
    Cell Transplant 14:11-9. 2005
    ..These interim results demonstrate survival, feasibility, and safety of autologous myoblast transplantation and suggest that this modality may offer a potential therapeutic treatment for end-stage heart disease...