Prasun K Datta

Summary

Affiliation: Temple University
Country: USA

Publications

  1. ncbi request reprint Differential nephron HO-1 expression following glomerular epithelial cell injury
    Prasun K Datta
    Laboratory of AIDS Pathogenesis and Molecular Therapeutics, Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19122, USA
    Nephron Exp Nephrol 103:e131-8. 2006
  2. ncbi request reprint Nitric oxide induces metallothionein-I gene expression in mesangial cells
    Prasun K Datta
    Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19122, USA
    Transl Res 148:180-7. 2006
  3. ncbi request reprint Regulatory effects of inducible nitric oxide synthase on cyclooxygenase-2 and heme oxygenase-1 expression in experimental glomerulonephritis
    Prasun K Datta
    Division of Nephrology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Nephrol Dial Transplant 21:51-7. 2006
  4. ncbi request reprint HIV and complement: hijacking an immune defense
    P K Datta
    Department of Neuroscience, Temple University School of Medicine, 1900 N 12th Street, Philadelphia, PA 19122, USA
    Biomed Pharmacother 60:561-8. 2006
  5. ncbi request reprint Effect of nitric oxide synthase inhibition on proteinuria in glomerular immune injury
    Prasun K Datta
    Center for Neurovirology Cancer Biology, Temple University, Philadelphia, Pennsylvania 19122, USA
    Exp Biol Med (Maywood) 231:576-84. 2006
  6. ncbi request reprint Long-term effect of heme oxygenase (HO)-1 induction in glomerular immune injury
    Prasun K Datta
    Temple University Center for Neurovirology and Cancer Biology, Philadelphia, Pennsylvania, USA
    J Lab Clin Med 147:150-5. 2006
  7. ncbi request reprint Superoxide dismutase mimetic preserves the glomerular capillary permeability barrier to protein
    Pu Duann
    Department of Medicine Division of Nephrology, University of Medicine and Dentistry, New Jersey Robert Wood Johnson Medicine School, New Brunswick, NJ 08903 0019, USA
    J Pharmacol Exp Ther 316:1249-54. 2006
  8. ncbi request reprint Interactions between inducible nitric oxide synthase and heme oxygenase-1 in glomerulonephritis
    Prasun K Datta
    Division of Nephrology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, P O Box 19, MEB 412, New Brunswick, NJ, USA
    Kidney Int 61:847-50. 2002
  9. ncbi request reprint Induction of metallothionein-I protects glomeruli from superoxide-mediated increase in albumin permeability
    Ram Sharma
    Department of Medicine, Division of Nephrology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Exp Biol Med (Maywood) 227:26-31. 2002
  10. ncbi request reprint Differential regulation of the rat heme oxygenase-1 expression by Ets oncoproteins in glomerular mesangial cells
    Prasad D K Dhulipala
    Department of Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903 0019, USA
    J Lab Clin Med 146:326-32. 2005

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Differential nephron HO-1 expression following glomerular epithelial cell injury
    Prasun K Datta
    Laboratory of AIDS Pathogenesis and Molecular Therapeutics, Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19122, USA
    Nephron Exp Nephrol 103:e131-8. 2006
    ..In this model, we assessed nephron distribution of the expression of the inducible HO isoform, HO-1, and the role of free radicals in modulating HO-1 expression...
  2. ncbi request reprint Nitric oxide induces metallothionein-I gene expression in mesangial cells
    Prasun K Datta
    Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19122, USA
    Transl Res 148:180-7. 2006
    ..These observations identify MT-I as a putative antioxidant system in NO-mediated mesangial cell injury...
  3. ncbi request reprint Regulatory effects of inducible nitric oxide synthase on cyclooxygenase-2 and heme oxygenase-1 expression in experimental glomerulonephritis
    Prasun K Datta
    Division of Nephrology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Nephrol Dial Transplant 21:51-7. 2006
    ....
  4. ncbi request reprint HIV and complement: hijacking an immune defense
    P K Datta
    Department of Neuroscience, Temple University School of Medicine, 1900 N 12th Street, Philadelphia, PA 19122, USA
    Biomed Pharmacother 60:561-8. 2006
    ....
  5. ncbi request reprint Effect of nitric oxide synthase inhibition on proteinuria in glomerular immune injury
    Prasun K Datta
    Center for Neurovirology Cancer Biology, Temple University, Philadelphia, Pennsylvania 19122, USA
    Exp Biol Med (Maywood) 231:576-84. 2006
    ..We conclude that NOS-catalyzed NO production is an important mechanism in regulating glomerular permeability to protein. This mechanism involves control of the bioavailability of superoxide...
  6. ncbi request reprint Long-term effect of heme oxygenase (HO)-1 induction in glomerular immune injury
    Prasun K Datta
    Temple University Center for Neurovirology and Cancer Biology, Philadelphia, Pennsylvania, USA
    J Lab Clin Med 147:150-5. 2006
    ..This effect could be mechanistically linked to blunting of the ability of infiltrating macrophages to cause injury or to changes in tubular handling of filtered protein...
  7. ncbi request reprint Superoxide dismutase mimetic preserves the glomerular capillary permeability barrier to protein
    Pu Duann
    Department of Medicine Division of Nephrology, University of Medicine and Dentistry, New Jersey Robert Wood Johnson Medicine School, New Brunswick, NJ 08903 0019, USA
    J Pharmacol Exp Ther 316:1249-54. 2006
    ..These observations indicate that SOD mimetics can preserve the glomerular permeability barrier to protein under conditions of oxidative stress from O2* production...
  8. ncbi request reprint Interactions between inducible nitric oxide synthase and heme oxygenase-1 in glomerulonephritis
    Prasun K Datta
    Division of Nephrology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, P O Box 19, MEB 412, New Brunswick, NJ, USA
    Kidney Int 61:847-50. 2002
    ..These observations prompted us to explore regulatory interactions between iNOS and HO-1 in anti-GBM nephritis...
  9. ncbi request reprint Induction of metallothionein-I protects glomeruli from superoxide-mediated increase in albumin permeability
    Ram Sharma
    Department of Medicine, Division of Nephrology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Exp Biol Med (Maywood) 227:26-31. 2002
    ..We conclude that MT-I gene products may play an important role in protecting the glomerular filtration barrier from the injury induced by reactive oxygen species in immune and/or nonimmune renal diseases...
  10. ncbi request reprint Differential regulation of the rat heme oxygenase-1 expression by Ets oncoproteins in glomerular mesangial cells
    Prasad D K Dhulipala
    Department of Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903 0019, USA
    J Lab Clin Med 146:326-32. 2005
    ..Furthermore, mutation of EBS-2 and 4 completely abolished Erg-2-mediated promoter activation. Our results support a role for Ets transcription factors in the regulation of rat hmox-1 gene expression in mesangial cells...
  11. pmc HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis
    Carlos A Barrero
    Department of Biochemistry, Temple University School of Medicine, Fels Institute, Philadelphia, Pennsylvania, USA
    PLoS ONE 8:e68376. 2013
    ..Furthermore, dysregulation of mitochondrial glutamate metabolism in macrophages can contribute to neurodegeneration via neuroexcitotoxic mechanisms in the context of NeuroAIDS. ..
  12. doi request reprint Epigenetics of µ-opioid receptors: intersection with HIV-1 infection of the central nervous system
    Patrick M Regan
    Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA, USA
    J Cell Physiol 227:2832-41. 2012
    ..Additionally, we suggest that differential regulation of newly identified MOR isoforms by opioids and HIV-1 has functional consequence in enhancing HIV-1 neurocognitive dysfunction...
  13. pmc Role of C/EBP-β, p38 MAPK, and MKK6 in IL-1β-mediated C3 gene regulation in astrocytes
    Jeffrey Maranto
    Department of Neuroscience, Temple University School of Medicine, 3500, N Broad Street, Philadelphia, Pennsylvania 19140, USA
    J Cell Biochem 112:1168-75. 2011
    ..These results suggest that the p38α, MAPK, and MKK6 play prominent roles in IL-1β and C/EBP-β-mediated C3 gene expression in astrocytes...
  14. ncbi request reprint Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cells
    Hui Zhao
    Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA
    Int J Cancer 109:65-70. 2004
    ....