Gerard J Criner

Summary

Affiliation: Temple University
Country: USA

Publications

  1. ncbi Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation
    Michael H Cho
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
    Respir Res 11:30. 2010
  2. ncbi Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study
    Nicholas D Giardino
    Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
    Respir Res 11:29. 2010
  3. ncbi Effect of lung volume reduction surgery on resting pulmonary hemodynamics in severe emphysema
    Gerard J Criner
    Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Am J Respir Crit Care Med 176:253-60. 2007
  4. ncbi National Emphysema Treatment Trial: the major outcomes of lung volume reduction surgery in severe emphysema
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 5:393-405. 2008
  5. ncbi A clinician's guide to the use of lung volume reduction surgery
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 5:461-7. 2008
  6. ncbi Biologic lung volume reduction in advanced upper lobe emphysema: phase 2 results
    Gerard J Criner
    Temple Lung Center, Temple University School of Medicine, 745 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140
    Am J Respir Crit Care Med 179:791-8. 2009
  7. ncbi Effects of lung volume reduction surgery on gas exchange and breathing pattern during maximum exercise
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple Lung Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Chest 135:1268-79. 2009
  8. ncbi Framing the forum: medical ethics in large-scale, interventional respiratory clinical trials
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple Lung Center, Temple University Hospital, 777 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 4:171-5; discussion 175. 2007
  9. ncbi Lung volume reduction surgery and lung volume reduction in advanced emphysema: who and why?
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Semin Respir Crit Care Med 31:348-64. 2010
  10. ncbi The National Emphysema Treatment Trial (NETT) Part II: Lessons learned about lung volume reduction surgery
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University, Philadelphia, Pennsylvania, USA
    Am J Respir Crit Care Med 184:881-93. 2011

Research Grants

  1. COPD Clinical Research Network & Clinical Research Skills Core Development
    Gerard Criner; Fiscal Year: 2007

Detail Information

Publications77

  1. ncbi Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation
    Michael H Cho
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA, USA
    Respir Res 11:30. 2010
    ..One reason may be heterogeneity in disease definition. Unsupervised learning approaches may assist in understanding disease heterogeneity...
  2. ncbi Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study
    Nicholas D Giardino
    Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
    Respir Res 11:29. 2010
    ..The purpose of this study is to determine whether there is an association between anxiety and functional measures, quality of life and dyspnea...
  3. ncbi Effect of lung volume reduction surgery on resting pulmonary hemodynamics in severe emphysema
    Gerard J Criner
    Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Am J Respir Crit Care Med 176:253-60. 2007
    ..To determine the effect of medical treatment versus lung volume reduction surgery (LVRS) on pulmonary hemodynamics...
  4. ncbi National Emphysema Treatment Trial: the major outcomes of lung volume reduction surgery in severe emphysema
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 5:393-405. 2008
    ..In this review, we summarize in one publication the major medical and surgical outcomes of NETT...
  5. ncbi A clinician's guide to the use of lung volume reduction surgery
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 5:461-7. 2008
    ..NETT investigators were also queried regarding the future directions of research in emphysema and the role that NETT played in shaping that future. The following article is a summary of the highlights of these discussions...
  6. ncbi Biologic lung volume reduction in advanced upper lobe emphysema: phase 2 results
    Gerard J Criner
    Temple Lung Center, Temple University School of Medicine, 745 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140
    Am J Respir Crit Care Med 179:791-8. 2009
    ..Biologic lung volume reduction (BioLVR) is a new endobronchial treatment for advanced emphysema that reduces lung volume through tissue remodeling...
  7. ncbi Effects of lung volume reduction surgery on gas exchange and breathing pattern during maximum exercise
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple Lung Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Chest 135:1268-79. 2009
    ..The National Emphysema Treatment Trial studied lung volume reduction surgery (LVRS) for its effects on gas exchange, breathing pattern, and dyspnea during exercise in severe emphysema...
  8. ncbi Framing the forum: medical ethics in large-scale, interventional respiratory clinical trials
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple Lung Center, Temple University Hospital, 777 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 4:171-5; discussion 175. 2007
    ..While this environment creates enormous opportunities for advances in healthcare, it also poses numerous challenges to the ethical conduct of clinical trials and raises numerous heretofore unconsidered issues...
  9. ncbi Lung volume reduction surgery and lung volume reduction in advanced emphysema: who and why?
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Semin Respir Crit Care Med 31:348-64. 2010
    ..This article summarizes the major results of the NETT and briefly reviews some preliminary results of studies examining new techniques of bronchoscopic lung volume reduction...
  10. ncbi The National Emphysema Treatment Trial (NETT) Part II: Lessons learned about lung volume reduction surgery
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University, Philadelphia, Pennsylvania, USA
    Am J Respir Crit Care Med 184:881-93. 2011
    ..In this review, we summarize what we currently know about the role of LVRS in the treatment of severe emphysema as a result of insights gained from the NETT and provide a brief review of the newer techniques of lung volume reduction...
  11. ncbi Alternatives to lung transplantation: lung volume reduction for COPD
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine and Temple Lung Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Clin Chest Med 32:379-97. 2011
    ....
  12. ncbi Care of the patient requiring invasive mechanical ventilation
    Gerard J Criner
    Temple Lung Center, Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Respir Care Clin N Am 8:575-92. 2002
    ....
  13. ncbi The National Emphysema Treatment Trial (NETT): Part I: Lessons learned about emphysema
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Temple University, School of Medicine, Philadelphia, PA 19140, USA
    Am J Respir Crit Care Med 184:763-70. 2011
    ..Herein, we provide a summary of the major NETT findings that provide insight into the evaluation and medical treatment of emphysema...
  14. ncbi Demographic, physiologic and radiographic characteristics of COPD patients taking chronic systemic corticosteroids
    Irene Swift
    Temple University, Philadelphia, Pennsylvania 19140, USA
    COPD 9:29-35. 2012
    ..They also had a higher percentage of emphysema (22.4 ± 1.9 vs. 14.0 ± 0.4;%, p = <0.0001) on CT scan. COPD patients that report using chronic systemic corticosteroids have more severe clinical, physiologic, and radiographic disease...
  15. ncbi Mortality and functional performance in severe emphysema after lung volume reduction or transplant
    Michael S Weinstein
    Divisions of Pulmonary and Critical Care Medicine and Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA, USA
    COPD 4:15-22. 2007
    ....
  16. ncbi Lung transplantation and lung volume reduction surgery versus transplantation in chronic obstructive pulmonary disease
    Namrata Patel
    Temple University School of Medicine, Temple Lung Center, Temple University Hospital, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 5:447-53. 2008
    ..Finally, we discuss the feasibility and role of lung transplantation after lung volume reduction surgery in the management of selected patients with chronic obstructive pulmonary disease...
  17. ncbi The chronic bronchitic phenotype of COPD: an analysis of the COPDGene Study
    Victor Kim
    Temple University School of Medicine, Philadelphia, PA 19140, USA
    Chest 140:626-33. 2011
    ..Despite its clinical significance, the chronic bronchitic phenotype in COPD remains poorly defined...
  18. ncbi Physiologic correlates of sleep quality in severe emphysema
    Samuel L Krachman
    Dept of Pulmonary, Critical Care, and Sleep, Temple University School of Medicine, Philadelphia, Pennsylvania, 19140, USA
    COPD 8:182-8. 2011
    ..Sleep quality is poor in severe emphysema. We hypothesized that in addition to nocturnal oxygen desaturation, the severity of airflow obstruction and degree of thoracic hyperinflation are responsible...
  19. ncbi Increased oxygen pulse after lung volume reduction surgery is associated with reduced dynamic hyperinflation
    Matthew R Lammi
    Section of Pulmonary and Critical Care Medicine, Temple University Hospital, 3401 N Broad St, 7th Floor Parkinson Pavilion, Philadelphia, PA 19140, USA
    Eur Respir J 40:837-43. 2012
    ..Reductions in DH correlated with increases in oxygen pulse during exercise. Reducing lung volume may improve stroke volume response to exercise by decreasing DH...
  20. ncbi Weight gain after lung reduction surgery is related to improved lung function and ventilatory efficiency
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, 785 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Am J Respir Crit Care Med 186:1109-16. 2012
    ..Lung volume reduction surgery (LVRS) is associated with weight gain in some patients, but the group that gains weight after LVRS and the mechanisms underlying this phenomenon have not been well characterized...
  21. ncbi Cardiac disease in chronic obstructive pulmonary disease
    Jeremy A Falk
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars Sinai Medical Center, for the David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Proc Am Thorac Soc 5:543-8. 2008
    ..Use of beta-blockers in the management of cardiac disease, while a theoretical concern in patients with increased airway resistance, is generally safe with the use of cardioselective agents...
  22. ncbi Effects of lung volume reduction surgery on sleep quality and nocturnal gas exchange in patients with severe emphysema
    Samuel L Krachman
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Chest 128:3221-8. 2005
    ..We hypothesized that associated with improvements in respiratory mechanics, lung volume reduction surgery (LVRS) would result in an improvement in both sleep quality and nocturnal oxygenation in patients with severe emphysema...
  23. ncbi Transplantation in chronic obstructive pulmonary disease
    Namrata Patel
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    COPD 3:149-62. 2006
    ..The respective roles of transplantation and lung volume reduction surgery as therapies for advanced disease will be outlined...
  24. ncbi Small airway pathology and bronchoreversibility in advanced emphysema
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, United States
    COPD 7:93-101. 2010
    ..However, some COPD patients demonstrate significant bronchodilator reversibility (BDR). The pathologic features associated with the presence or absence of this phenomenon are not known...
  25. ncbi Total lung capacity by plethysmography and high-resolution computed tomography in COPD
    Jamie L Garfield
    Department of Pulmonary and Critical Care Medicine and Department of Radiology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Int J Chron Obstruct Pulmon Dis 7:119-26. 2012
    ..To characterize and compare total lung capacity (TLC) measured by plethysmography with high-resolution computed tomography (HRCT), and to identify variables that predict the difference between the two modalities...
  26. ncbi African Americans and men with severe COPD have a high prevalence of osteoporosis
    Lihua Li
    Division of Pulmonary and Critical Care, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    COPD 5:291-7. 2008
    ..006, OR 0.974). Osteoporosis is highly prevalent in severe COPD, and affects males and African Americans to a similar degree as females and Whites. Osteoporosis should be considered in severe COPD regardless of race or gender...
  27. ncbi Complications of long-term mechanical ventilation
    Wissam M Chatila
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Respir Care Clin N Am 8:631-47. 2002
    ..Efforts should not be spared to prevent and aggressively treat these complications while continuing plans to wean and rehabilitate the patient...
  28. ncbi Sex differences in severe pulmonary emphysema
    Fernando J Martinez
    University of Michigan, Division of Pulmonary and Critical Care Medicine, Ann Arbor, Michigan 48109 0360, USA
    Am J Respir Crit Care Med 176:243-52. 2007
    ..Limited data on sex differences in advanced COPD are available...
  29. ncbi Small airway mucous metaplasia and inflammation in chronic obstructive pulmonary disease
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    COPD 5:329-38. 2008
    ..CD3(+) and CD8(+) lymphocytic inflammation is related to small airway mucous metaplasia in COPD and may play a causative role in its development...
  30. ncbi Treatment of persistent pulmonary air leaks using endobronchial valves
    John M Travaline
    Temple University School of Medicine, Philadelphia, PA, USA
    Chest 136:355-60. 2009
    ..To our knowledge, this article presents the largest series of patients with prolonged air leaks treated with an endobronchial valve...
  31. ncbi Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease
    Prescott G Woodruff
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Am J Respir Crit Care Med 181:438-45. 2010
    ..Epidermal growth factor receptor (EGFR) activation is implicated in mucin hypersecretion in chronic obstructive pulmonary disease (COPD)...
  32. ncbi New concepts in the pathobiology of chronic obstructive pulmonary disease
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Proc Am Thorac Soc 5:478-85. 2008
    ..Further research should focus on how these new concepts in lung inflammation interact to cause the various aspects of COPD pathology...
  33. ncbi Hospitalized acute exacerbation of COPD impairs flow and nitroglycerin-mediated peripheral vascular dilation
    Nathaniel Marchetti
    Department of Physiology, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    COPD 8:60-5. 2011
    ..The systemic vascular impairment that occurs during AECOPD may partially explain the observed increased in cardiac morbidity and mortality that occur in this population...
  34. ncbi Smoking patterns in African Americans and whites with advanced COPD
    Wissam M Chatila
    Department of Pulmonary and Critical Care, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Chest 125:15-21. 2004
    ..Causes and explanations for smoking-related racial differences on the respiratory system have not been determined...
  35. ncbi High incidence of venous thromboembolic events in lung transplant recipients
    Erika S Kahan
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    J Heart Lung Transplant 26:339-44. 2007
    ..Characterization of risk factors for VTEs in LTRs is lacking. We identified the incidence and risk factors associated with post-transplant VTEs...
  36. ncbi Chronic bronchitis and chronic obstructive pulmonary disease
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Am J Respir Crit Care Med 187:228-37. 2013
    ..Herein we review the epidemiology of CB, the evidence behind its clinical consequences, the current understanding of the pathophysiology of goblet cell hyperplasia in COPD, and current therapies for CB...
  37. ncbi Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization
    Prescott G Woodruff
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, California, USA
    COPD 8:21-9. 2011
    ..Leukotrienes have been implicated in the pathogenesis of acute exacerbations of COPD, but leukotriene modifiers have not been studied as a possible therapy for exacerbations...
  38. ncbi Sleep and long-term ventilation
    Samuel L Krachman
    Division of Pulmonary and Critical Care, Temple University School of Medicine, 767 Parkinson Pavilion, Broad and Tioga Streets, Philadelphia, PA 19140, USA
    Respir Care Clin N Am 8:611-29. 2002
    ..Improved daytime symptoms and gas exchange, with the suggestion of a decrease in morbidity and mortality, support the use of long-term mechanical ventilation during sleep in selected patients with these disorders...
  39. ncbi Comorbidities in chronic obstructive pulmonary disease
    Wissam M Chatila
    Division of Pulmonary and Critical Care Division, Temple University School of Medicine, 3401 N Broad Street, Philadelphia PA, 19140, USA
    Proc Am Thorac Soc 5:549-55. 2008
    ....
  40. ncbi The effects of high-flow vs low-flow oxygen on exercise in advanced obstructive airways disease
    Wissam Chatila
    Division of Pulmonary and Critical Care Medicine, 763 PP, Temple University School of Medicine, 3401 N Broad St, Philadelphia, PA 19140, USA
    Chest 126:1108-15. 2004
    ..This study compared the effects of high flows of humidified oxygen to conventional low-flow oxygen (LFO) delivery at rest and during exercise in patients with COPD...
  41. ncbi Effect of bilateral lung volume reduction surgery on FEV1 decline in severe emphysema
    John M Travaline
    Division of Pulmonary and Critical Care Medicine and Cardiothoracic Surgery, Temple University School of Medicine, 3401 North Broad St, Philadelphia, Pennsylvania 19140, USA
    COPD 2:203-8. 2005
    ..To examine whether lung volume reduction surgery (LVRS) alters the anticipated natural rates of decline in FEV1...
  42. ncbi Assessment tools for chronic obstructive pulmonary disease: do newer metrics allow for disease modification?
    Donald A Mahler
    Division of Pulmonary and Critical Care Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Proc Am Thorac Soc 4:507-11. 2007
    ..Finally, we consider the impact of disease modifying therapies on some of these metrics...
  43. ncbi Exercise testing in severe emphysema: association with quality of life and lung function
    Cynthia D Brown
    Division of Pulmonary and Critical Care Medicine, University of Virginia, VA, USA
    COPD 5:117-24. 2008
    ..Moreover, the 6MWT may be a better test of functional capacity given its greater association with QOL measures whereas CPX is a better test of physiologic impairment...
  44. ncbi The acute and chronic effects of bullectomy on cardiovascular function at rest and during exercise
    Nathaniel Marchetti
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    J Thorac Cardiovasc Surg 135:205-6, 206.e1. 2008
  45. ncbi Ambulatory home oxygen: what is the evidence for benefit, and who does it help?
    Gerard J Criner
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Respir Care 58:48-64. 2013
    ....
  46. ncbi Design of the Endobronchial Valve for Emphysema Palliation Trial (VENT): a non-surgical method of lung volume reduction
    Charlie Strange
    Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston, SC, USA
    BMC Pulm Med 7:10. 2007
    ....
  47. ncbi Small airway morphometry and improvement in pulmonary function after lung volume reduction surgery
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Temple Lung Center, Temple University Hospital, 777 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Am J Respir Crit Care Med 171:40-7. 2005
    ..We conclude that small airway morphometry and lung histopathology in patients with severe emphysema have an important influence on changes in FEV(1) 6 months after LVRS...
  48. ncbi The effect of chronic sputum production on respiratory symptoms in severe COPD
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    COPD 8:114-20. 2011
    ..We sought to characterize the daily burden of chronic sputum production in severe COPD and the phenotype of those with chronic sputum symptoms...
  49. ncbi Chronic cough and dyspnea in ice hockey players after an acute exposure to combustion products of a faulty ice resurfacer
    Erika S Kahan
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    Lung 185:47-54. 2007
    ..IOS showed evidence of increased airway resistance and small-airway disease, which correlated with patient symptoms...
  50. ncbi Treatment of Guillain-Barré syndrome induced by cyclosporine in a lung transplant patient
    Jeremy A Falk
    Division of Pulmonary and Critical Care Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    J Heart Lung Transplant 25:140-3. 2006
    ..We propose the discontinuation of cyclosporine and initiation of plasmapheresis as a treatment for cyclosporine-associated Guillain-Barré syndrome...
  51. ncbi Lung volume reduction surgery as a bridge to lung transplantation
    Francis C Cordova
    Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Am J Respir Med 1:313-24. 2002
    ....
  52. ncbi Impact of whole-body rehabilitation in patients receiving chronic mechanical ventilation
    Ubaldo J Martin
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA, USA
    Crit Care Med 33:2259-65. 2005
    ..Whole-body rehabilitation should be considered a significant component of their therapy...
  53. ncbi Survival in Patients Receiving Prolonged Ventilation: Factors that Influence Outcome
    A James Mamary
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Clin Med Insights Circ Respir Pulm Med 5:17-26. 2011
    ..Our objective is to comprehensively characterize patients admitted to a Ventilator Rehabilitation Unit (VRU) for weaning and identify characteristics associated with survival...
  54. ncbi Long-term ventilation introduction and perspectives
    Gerard J Criner
    Temple Lung Center, Temple University School of Medicine, 3401 North Broad Street, Suite 785, Philadelphia, PA 19140, USA
    Respir Care Clin N Am 8:345-53, v. 2002
    ..These patients require a highly organized and integrated care plan that has sufficient and prolonged administrative oversight to ensure optimum outcome and reduce costs...
  55. ncbi Pulmonary tumor embolism
    Matthew Lammi
    Division of Pulmonary and Critical Care Medicine, Temple University Hospital, 3401 N Broad Street, 7th Floor Parkinson Pavilion, Philadelphia, PA 19140, USA
    Lung 188:441-3. 2010
    ..It is important to recognize this entity, because there have been some case reports of cure. The usual mechanism of death is progressive right heart failure; sudden death from tumor embolism has rarely been described...
  56. ncbi Full face mask for noninvasive positive-pressure ventilation in patients with acute respiratory failure
    Bruce Roy
    Division of Pulmonary and Critical Care Medicine, 3401 N Broad St, Philadelphia, PA 19140 5103, USA
    J Am Osteopath Assoc 107:148-56. 2007
    ..Mask leak and intolerance due to facial discomfort or claustrophobia often occur with NPPV and are frequently cited reasons for treatment failure...
  57. ncbi Frontiers in emphysema research
    Victor Kim
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    Semin Thorac Cardiovasc Surg 19:135-41. 2007
    ..We are optimistic that novel therapies like gene therapy and advanced antiinflammatory agents will be in our future. Judging by the progress made in the last decade, these tools may soon become a reality...
  58. ncbi Characterization of functional, radiologic and lung function recovery post-treatment of hot tub lung. A case report and review of the literature
    Nathaniel Marchetti
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Lung 182:271-7. 2004
    ..Prednisone therapy offered minimal further improvement while anti-MAC therapy provided no further improvement. These results are suggestive of a hypersensitivity pneumonitis rather than an infectious etiology...
  59. ncbi Six-minute walk distance in chronic obstructive pulmonary disease: reproducibility and effect of walking course layout and length
    Frank Sciurba
    Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
    Am J Respir Crit Care Med 167:1522-7. 2003
    ..The training effect found in these patients with severe emphysema is less than in previous reports of patients with chronic obstructive pulmonary disease. Furthermore, the layout of the track may influence the 6-minute walk performance...
  60. ncbi Efficacy of tiotropium inhalation powder in african-american patients with chronic obstructive pulmonary disease
    Gerard J Criner
    Temple University School of Medicine, Temple University Hospital, Philadelphia, PA 19140, USA
    COPD 5:35-41. 2008
    ..In patients of African descent, possible differences have been observed for inhaled beta-agonists. However, pharmacologic responsiveness to a long-acting anticholinergic has not been prospectively evaluated...
  61. ncbi Automated telecommunication to obtain longitudinal follow-up in a multicenter cross-sectional COPD study
    Jeffrey I Stewart
    Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
    COPD 9:466-72. 2012
    ..To obtain follow-up data on patient's vital status and outcomes, the COPDGene Longitudinal Follow-up (LFU) Program was developed to supplement its parent study...
  62. ncbi Respiratory failure after lung transplantation
    Wissam M Chatila
    Division of Pulmonary and Critical Care Medicine, Temple University School of Medicine, 3401 N Broad St, Philadelphia, PA 19140, USA
    Chest 123:165-73. 2003
    ..To characterize patients who acquired postoperative respiratory failure after lung transplantation (LT), and to identify risks associated with postoperative respiratory failure and poor surgical outcome...
  63. ncbi Circulating tissue factor procoagulant activity is elevated in stable moderate to severe chronic obstructive pulmonary disease
    Vijender Reddy Vaidyula
    Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Thromb Res 124:259-61. 2009
    ..Chronic obstructive pulmonary disease (COPD) patients have increased risk for cardiovascular mortality and venous thromboembolism. Tissue factor (TF) is the physiological initiating mechanism for blood coagulation and is pro-inflammatory...
  64. ncbi The small airways in chronic obstructive pulmonary disease: pathology and effects on disease progression and survival
    Jeffrey I Stewart
    Pulmonary and Critical Care Medicine, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA
    Curr Opin Pulm Med 19:109-15. 2013
    ..The relative contributions of these two pathologic states vary from person to person. Having the ability to phenotype patients into predominately small airways disease or emphysema may affect the clinical management...
  65. ncbi Tiotropium bromide for chronic obstructive pulmonary disease
    A James Mamary
    Temple Lung Center, 745 Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA
    Expert Rev Respir Med 3:211-20. 2009
    ..Additional review of airway muscarinic receptor physiology and cholinergic pathobiology relevant to COPD and asthma provides context for future experimental and therapeutic roles for tiotropium...
  66. ncbi Intralobar sequestration in the middle-aged and elderly adult: recognition and radiographic evaluation
    Gerard Petersen
    Division of Pulmonary Disease and Critical Care Medicine, Temple University Hospital, Philadelphia, PA 19140, USA
    J Thorac Cardiovasc Surg 126:2086-90. 2003
  67. ncbi Conversion to bosentan from prostacyclin infusion therapy in pulmonary arterial hypertension: a pilot study
    M Kathryn Steiner
    Tufts New England Medical Center, Boston, MA, USA
    Chest 130:1471-80. 2006
    ..We assessed the efficacy of bosentan in transitioning from prostacyclin infusions in patients with pulmonary arterial hypertension (PAH)...
  68. ncbi Cardiac safety of formoterol 12 microg twice daily in patients with chronic obstructive pulmonary disease
    Sammy C Campbell
    Arizona Respiratory Center, University of Arizona and Pulmonary Section, VA Medical Center, Southern Arizona VA Health Care System, Tucson, AZ, USA
    Pulm Pharmacol Ther 20:571-9. 2007
    ..This prospective, multicenter, randomized, double-blind, placebo-controlled study compared the cardiac safety of formoterol and placebo in patients with COPD...
  69. ncbi Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology
    James C Hogg
    University of British Columbia iCAPTURE Centre for Cardiovascular and Pulmonary Research, St Paul s Hospital, Vancouver, BC, Canada
    Am J Respir Crit Care Med 176:454-9. 2007
    ..COPD is associated with reduced life expectancy...
  70. ncbi Lung elastic recoil does not correlate with pulmonary hemodynamics in severe emphysema
    Jeremy A Falk
    Department of Medicine, Cedars Sinai Medical Center, David Geffen School of Medicine at UCLA, 8700 Beverly Blvd, Room 6732, Los Angeles, CA 90048, USA
    Chest 132:1476-84. 2007
    ..Whether a relationship exists between static elastic lung recoil and pulmonary hemodynamics in severe emphysema, however, is unknown...
  71. ncbi Predictors of operative mortality and cardiopulmonary morbidity in the National Emphysema Treatment Trial
    Keith S Naunheim
    Division of Cardiothoracic Surgery, St Louis University Health Sciences Center, St Louis, Mo 63110 0250, USA
    J Thorac Cardiovasc Surg 131:43-53. 2006
    ..We sought to identify predictors of operative mortality, pulmonary morbidity, and cardiovascular morbidity after lung volume reduction surgery...
  72. ncbi Long-term follow-up of patients receiving lung-volume-reduction surgery versus medical therapy for severe emphysema by the National Emphysema Treatment Trial Research Group
    Keith S Naunheim
    St Louis University, 3635 Vista Blvd, St Louis, Mo 63110 0250, USA
    Ann Thorac Surg 82:431-43. 2006
    ..Two additional years of follow-up provide valuable information regarding durability...
  73. ncbi Advanced emphysema in African-American and white patients: do differences exist?
    Wissam M Chatila
    Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, USA
    Chest 130:108-18. 2006
    ..Epidemiologic studies have not addressed, nor explained, the observed racial differences in emphysema...
  74. ncbi Pulmonary diseases and the heart
    MeiLan K Han
    University of Michigan Health System, Ann Arbor, MI, USA
    Circulation 116:2992-3005. 2007
    ....
  75. ncbi Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial
    Robert W Taylor
    Critical Care Medicine, St Louis University/St John's Mercy Medical Center, St Louis, MO, USA
    JAMA 291:1603-9. 2004
    ....
  76. ncbi Optimal treatment of chronic obstructive pulmonary disease: the search for the magic combination of inhaled bronchodilators and corticosteroids
    Gerard J Criner
    Ann Intern Med 146:606-8. 2007
  77. ncbi National Emphysema Treatment Trial: the state-of-the-art of the evaluation and treatment of emphysema. Introduction
    Gerard J Criner
    Proc Am Thorac Soc 5:380. 2008

Research Grants2

  1. COPD Clinical Research Network & Clinical Research Skills Core Development
    Gerard Criner; Fiscal Year: 2007
    ..abstract_text> ..