Seo Hee Cho
Affiliation: Temple University
Cho S, Song J, Shin J, Kim S. Neonatal disease environment limits the efficacy of retinal transplantation in the LCA8 mouse model. BMC Ophthalmol. 2016;16:193 pubmed
Cho S, Kim J, Simons D, Song J, Le J, Swindell E, et al
. Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. Hum Mol Genet. 2012;21:2663-76 pubmed publisher
..Our data uncover the indispensible role of Pals1 in retinal development, likely involving the maintenance of retinal polarity and survival of retinal neurons, thus providing the basis for the pathologic mechanisms of LCA8. ..
Song J, Park R, Kim J, Hughes L, Lu L, Kim S, et al
. Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014;386:281-90 pubmed publisher
..Taken together, our results shed new light on Yap's indispensable and novel organizing role in mammalian organ size control by coordinating multiple events including cell proliferation, differentiation, and polarity. ..
Kim J, Song J, Karnam S, Park J, Lee J, Kim S, et al
. Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns. 2015;17:31-7 pubmed publisher
..These findings suggest that core Crumbs polarity complex proteins exert common and independent functions depending on cellular context. ..
Kim J, Park R, Lee J, Shin J, Nickas J, Kim S, et al
. Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016;419:336-347 pubmed publisher